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Showing 1 to 12 of 32 entries
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Corrigendum: Complex pectin metabolism by gut bacteria reveals novel catalytic functions.

Nature

Ndeh D, Rogowski A, Cartmell A, Luis AS, Baslé A, Gray J, Venditto I, Briggs J, Zhang X, Labourel A, Terrapon N, Buffetto F, Nepogodiev S, Xiao Y, Field RA, Zhu Y, O'Neill MA, Urbanowicz BR, York WS, Davies GJ, Abbott DW, Ralet MC, Martens EC, Henrissat B, Gilbert HJ.
PMID: 29411780
Nature. 2017 Aug 31;548(7669):612. doi: 10.1038/nature23659. Epub 2017 Aug 23.

This corrects the article DOI: 10.1038/nature21725.

Synthetic Cyclic Oligosaccharides-Syntheses and Structural Properties of a Cyclo[(1 → 4)-α-L-rhamnopyranosyl-(1 → 4)-α-D-mannopyranosyl]trioside and -tetraoside.

Chemistry (Weinheim an der Bergstrasse, Germany)

Ashton PR, Brown CL, Menzer S, Nepogodiev SA, Stoddart JF, Williams DJ.
PMID: 29178230
Chemistry. 1996 May;2(5):580-591. doi: 10.1002/chem.19960020518.

An efficient polycondensation-cyclization approach to the synthesis of cyclodextrin analogues is demonstrated by the preparation of cyclohexaoside 1 and cyclooctaoside 2. The key intermediate, disaccharide 3, bearing the cyanoethylidene group as a glycosyl donor function and the trityloxy group...

Methodological issues in economic evaluations of emergency transport systems in low-income and middle-income countries.

BMJ global health

Lilford R, Nepogodiev D, Chilton PJ, Watson SI, Erlangga D, Diggle P, Girling AJ, Sculpher M.
PMID: 33737285
BMJ Glob Health. 2021 Mar;6(3). doi: 10.1136/bmjgh-2020-004723.

A recent systematic review identified few papers on the economic evaluation of systems for emergency transport of acutely ill or injured patients. In addition, we found no articles dealing with the methodological challenges posed by such studies in low-income...

Lipopolysaccharide associated with β-2,6 fructan mediates TLR4-dependent immunomodulatory activity in vitro.

Carbohydrate polymers

Young ID, Nepogodiev SA, Black IM, Le Gall G, Wittmann A, Latousakis D, Visnapuu T, Azadi P, Field RA, Juge N, Kawasaki N.
PMID: 34893207
Carbohydr Polym. 2022 Feb 01;277:118606. doi: 10.1016/j.carbpol.2021.118606. Epub 2021 Aug 26.

Levan, a β-2,6 fructofuranose polymer produced by microbial species, has been reported for its immunomodulatory properties via interaction with toll-like receptor 4 (TLR4) which recognises lipopolysaccharide (LPS). However, the molecular mechanisms underlying these interactions remain elusive. Here, we investigated...

Cyclodextrin-Based Catenanes and Rotaxanes.

Chemical reviews

Nepogodiev SA, Stoddart JF.
PMID: 11848954
Chem Rev. 1998 Jul 30;98(5):1959-1976. doi: 10.1021/cr970049w.

No abstract available.

Stiff, and sticky in the right places: the dramatic influence of preorganizing guest binding sites on the hydrogen bond-directed assembly of rotaxanes.

Journal of the American Chemical Society

Gatti FG, Leigh DA, Nepogodiev SA, Slawin AM, Teat SJ, Wong JK.
PMID: 11414832
J Am Chem Soc. 2001 Jun 27;123(25):5983-9. doi: 10.1021/ja001697r.

Structural rigidity and the preorganization of thread binding sites are shown to have a major influence on template efficiency in the synthesis of hydrogen bond-assembled rotaxanes. Preorganization is so effective, in fact, that with good hydrogen bond acceptors (amides)...

Click chemistry oligomerisation of azido-alkyne-functionalised galactose accesses triazole-linked linear oligomers and macrocycles that inhibit .

Tetrahedron

Campo VL, Ivanova IM, Carvalho I, Lopes CD, Carneiro ZA, Saalbach G, Schenkman S, da Silva JS, Nepogodiev SA, Field RA.
PMID: 26435551
Tetrahedron. 2015 Sep 30;71(39):7344-7353. doi: 10.1016/j.tet.2015.04.085.

Reaction of 2-(2-(2-azidoethoxy)ethoxy)ethyl 6-

Synthesis of a 2,3,4-triglycosylated rhamnoside fragment of rhamnogalacturonan-II side chain A using a late stage oxidation approach.

The Journal of organic chemistry

Chauvin AL, Nepogodiev SA, Field RA.
PMID: 15675855
J Org Chem. 2005 Feb 04;70(3):960-6. doi: 10.1021/jo0482864.

Pectic polysaccharide RG-II, a key component of plant primary cell walls, is known to exist as a dimer formed by means of borate diester cross-links between apiosyl residues of one of its constituent side-chain oligosaccharides. Described herein is the...

Defining our destiny: trainee working group consensus statement on the future of emergency surgery training in the United Kingdom.

World journal of emergency surgery : WJES

Sharrock AE, Gokani VJ, Harries RL, Pearce L, Smith SR, Ali O, Chu H, Dubois A, Ferguson H, Humm G, Marsden M, Nepogodiev D, Venn M, Singh S, Swain C, Kirkby-Bott J.
PMID: 26161133
World J Emerg Surg. 2015 Jun 30;10:26. doi: 10.1186/s13017-015-0019-4. eCollection 2015.

The United Kingdom National Health Service treats both elective and emergency patients and seeks to provide high quality care, free at the point of delivery. Equal numbers of emergency and elective general surgical procedures are performed, yet surgical training...

Erratum to 'Perioperative mortality as a meaningful indicator: Challenges and solutions for measurement, interpretation, and health system improvement' [Anaesth. Crit. Care Pain Med. 39 (5) (2020) 673-681].

Anaesthesia, critical care & pain medicine

Ng-Kamstra JS, Nepogodiev D, Lawani I, Bhangu A.
PMID: 33109482
Anaesth Crit Care Pain Med. 2020 Dec;39(6):895. doi: 10.1016/j.accpm.2020.10.005. Epub 2020 Oct 24.

No abstract available.

Pan-genome analysis identifies intersecting roles for .

eLife

Pacheco-Moreno A, Stefanato FL, Ford JJ, Trippel C, Uszkoreit S, Ferrafiat L, Grenga L, Dickens R, Kelly N, Kingdon AD, Ambrosetti L, Nepogodiev SA, Findlay KC, Cheema J, Trick M, Chandra G, Tomalin G, Malone JG, Truman AW.
PMID: 34792466
Elife. 2021 Dec 31;10. doi: 10.7554/eLife.71900.

Agricultural soil harbors a diverse microbiome that can form beneficial relationships with plants, including the inhibition of plant pathogens.

Corrigendum to "Synthesis of glyceryl glycosides related to A-type prymnesin toxins" Carbohydr. Res. 463 (2018) 14-23.

Carbohydrate research

Hems ES, Nepogodiev SA, Rejzek M, Field RA.
PMID: 30312878
Carbohydr Res. 2018 Dec;470:26. doi: 10.1016/j.carres.2018.09.004. Epub 2018 Oct 09.

No abstract available.

Showing 1 to 12 of 32 entries