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Showing 1 to 12 of 188 entries
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Impact of the New Delhi metallo-beta-lactamase on beta-lactam antibiotics.

Infection and drug resistance

Zmarlicka MT, Nailor MD, Nicolau DP.
PMID: 26345624
Infect Drug Resist. 2015 Aug 24;8:297-309. doi: 10.2147/IDR.S39186. eCollection 2015.

Since the first New Delhi metallo-beta-lactamase (NDM) report in 2009, NDM has spread globally causing various types of infections. NDM-positive organisms produce in vitro resistance phenotypes to carbapenems and many other antimicrobials. It is thus surprising that the literature...

Stability of Ertapenem 100 mg/mL at Room Temperature.

The Canadian journal of hospital pharmacy

Kuti JL, Nicolau DP.
PMID: 27403009
Can J Hosp Pharm. 2016 May-Jun;69(3):256-9. Epub 2016 Jun 30.

No abstract available.

Interaction of demographic factors with the results of the surgery for degenerative disease of the cervical spine: a retrospective evaluation.

Revista brasileira de ortopedia

Dias CGP, Roberto BB, Basaglia L, Lenza M, Nicolau RJ, Ferretti M.
PMID: 29062823
Rev Bras Ortop. 2017 Aug 24;52(5):575-581. doi: 10.1016/j.rboe.2017.08.007. eCollection 2017.

OBJECTIVE: Degenerative disease of the cervical spine is a frequent source of intermittent neck pain, where the predominant symptom is axial neck pain. The indications for surgical treatment are reserved for the cases where the conservative treatment has not...

Technological and sensorial role of yeast .

Journal of food science and technology

Apostu PM, Mihociu TE, Nicolau AI.
PMID: 28928505
J Food Sci Technol. 2017 Aug;54(9):2653-2660. doi: 10.1007/s13197-017-2696-3. Epub 2017 Jul 12.

This study shows that apart from acting as nutritional value improver, yeast β-glucan can be successfully used to reformulate meat products. When added to meat batters, yeast derived ingredients containing β-glucans (GOLDCELL

In Vitro Activity of Cefepime/AAI101 and Comparators against Cefepime Non-susceptible Enterobacteriaceae.

Pathogens (Basel, Switzerland)

Crandon JL, Nicolau DP.
PMID: 26295262
Pathogens. 2015 Aug 18;4(3):620-5. doi: 10.3390/pathogens4030620.

We evaluated the in vitro potency of cefepime combined with AAI101, a novel extended-spectrum β-lactamase inhibitor, against a population of clinical Escherichia coli and Klebsiella pneumoniae collected from USA hospitals. Of the 223 cefepime non-susceptible isolates, 95% were ceftazidime...

Discovery and Characterization of a Water-Soluble Prodrug of a Dual Inhibitor of Bacterial DNA Gyrase and Topoisomerase IV.

ACS medicinal chemistry letters

O'Dowd H, Shannon DE, Chandupatla KR, Dixit V, Engtrakul JJ, Ye Z, Jones SM, O'Brien CF, Nicolau DP, Tessier PR, Crandon JL, Song B, Macikenas D, Hanzelka BL, Le Tiran A, Bennani YL, Charifson PS, Grillot AL.
PMID: 26191374
ACS Med Chem Lett. 2015 Jun 22;6(7):822-6. doi: 10.1021/acsmedchemlett.5b00196. eCollection 2015 Jul 09.

Benzimidazole 1 is the lead compound resulting from an antibacterial program targeting dual inhibitors of bacterial DNA gyrase and topoisomerase IV. With the goal of improving key drug-like properties, namely, the solubility and the formulability of 1, an effort...

The Smartphone-Based Offline Indoor Location Competition at IPIN 2016: Analysis and Future Work.

Sensors (Basel, Switzerland)

Torres-Sospedra J, Jiménez AR, Knauth S, Moreira A, Beer Y, Fetzer T, Ta VC, Montoliu R, Seco F, Mendoza-Silva GM, Belmonte O, Koukofikis A, Nicolau MJ, Costa A, Meneses F, Ebner F, Deinzer F, Vaufreydaz D, Dao TK, Castelli E.
PMID: 28287447
Sensors (Basel). 2017 Mar 10;17(3). doi: 10.3390/s17030557.

This paper presents the analysis and discussion of the off-site localization competition track, which took place during the Seventh International Conference on Indoor Positioning and Indoor Navigation (IPIN 2016). Five international teams proposed different strategies for smartphone-based indoor positioning...

Angular scattering of 1-50 keV ions through graphene and thin carbon foils: potential applications for space plasma instrumentation.

The Review of scientific instruments

Ebert RW, Allegrini F, Fuselier SA, Nicolaou G, Bedworth P, Sinton S, Trattner KJ.
PMID: 24689570
Rev Sci Instrum. 2014 Mar;85(3):033302. doi: 10.1063/1.4866850.

We present experimental results for the angular scattering of ~1-50 keV H, He, C, O, N, Ne, and Ar ions transiting through graphene foils and compare them with scattering through nominal ~0.5 μg cm(-2) carbon foils. Thin carbon foils...

[The High Committee of public health: an experience of 10 years].

Bulletin de l'Academie nationale de medecine

Nicolas G, Sambuc R.
PMID: 12669365
Bull Acad Natl Med. 2002;186(8):1503-11; discussion 1511-3.

According to The Patients' Rights law of 4 March 2002, a High Council on Health is presently to supersede the High Committee on Public Health created in december 1991. For the last ten years, the HCPH has fulfilled its...

Infusion phlebitis: relative incidence associated with cefuroxime administered by intermittent and continuous infusion.

Clinical drug investigation

Owens CA, Ambrose PG, Quintiliani R, Nightingale CH, Nicolau DP.
PMID: 18370511
Clin Drug Investig. 1998;15(6):531-5. doi: 10.2165/00044011-199815060-00010.

No abstract available.

Detection of putative new mutacins by bioinformatic analysis using available web tools.

BioData mining

Nicolas GG.
PMID: 21756306
BioData Min. 2011 Jul 14;4:22. doi: 10.1186/1756-0381-4-22.

In order to characterise new bacteriocins produced by Streptococcus mutans we perform a complete bioinformatic analyses by scanning the genome sequence of strains UA159 and NN2025. By searching in the adjacent genomic context of the two-component signal transduction system...

Influence of ticlopidine on the development of experimental Staphylococcus aureus endocarditis.

International journal of antimicrobial agents

Nicolau DP, Tessier PR, Nightingale CH, Quintiliani R.
PMID: 18611768
Int J Antimicrob Agents. 1996 Oct;7(4):271-4. doi: 10.1016/s0924-8579(96)00337-8.

Previously, we have shown that aspirin administration reduces the bacterial density and weight of aortic vegetations in a rabbit model of Staphylococcus aureus endocarditis. In the present paper, we sought to determine if ticlopidine, another potent inhibitor of platelet...

Showing 1 to 12 of 188 entries