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Showing 1 to 12 of 46 entries
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Human Bioequivalence Study of Clarithromycin from Two Tablet Formulations after Single Oral Administration.

Clinical drug investigation

Niopas I, Daftsios AC, Nikolaidis N.
PMID: 27517551
Clin Drug Investig. 2001 Mar;21(3):211-7. doi: 10.2165/00044011-200121030-00007.

OBJECTIVE: The objective of this study was to compare the relative bioavailability and bioequivalence of a test (Claromycin®, GA Pharmaceuticals) and a reference (Klaricid®, Abbott) tablet containing 500mg clarithromycin in healthy volunteers under fasting conditions.METHODS: This was a nonblinded,...

Seismic evidence for overpressured subducted oceanic crust and megathrust fault sealing.

Nature

Audet P, Bostock MG, Christensen NI, Peacock SM.
PMID: 19122639
Nature. 2009 Jan 01;457(7225):76-8. doi: 10.1038/nature07650.

Water and hydrous minerals play a key part in geodynamic processes at subduction zones by weakening the plate boundary, aiding slip and permitting subduction-and indeed plate tectonics-to occur. The seismological signature of water within the forearc mantle wedge is...

Toward a reverse hierarchy of halogen bonding between bromine and iodine.

Faraday discussions

Aubert E, Espinosa E, Nicolas I, Jeannin O, Fourmigué M.
PMID: 28745381
Faraday Discuss. 2017 Oct 13;203:389-406. doi: 10.1039/c7fd00067g.

We compare here the halogen bond characteristics of bimolecular adducts involving either N-bromo- or N-iodosaccharin as strong halogen bond donors, with 4-picoline as a common XB acceptor. In the NBSac·Pic system, the bromine atom of NBSac is displaced toward...

Targeting of copper-trafficking chaperones causes gene-specific systemic pathology in .

Biology open

Theotoki EI, Velentzas AD, Katarachia SA, Papandreou NC, Kalavros NI, Pasadaki SN, Giannopoulou AF, Giannios P, Iconomidou VA, Konstantakou EG, Anastasiadou E, Papassideri IS, Stravopodis DJ.
PMID: 31575544
Biol Open. 2019 Oct 15;8(10). doi: 10.1242/bio.046961.

Copper, a transition metal, is an essential component for normal growth and development. It acts as a critical co-factor of many enzymes that play key roles in diverse cellular processes. The present study attempts to investigate the regulatory functions...

Pediatric infratentorial subdural empyema: A case report.

Surgical neurology international

Neromyliotis E, Giakoumettis D, Drosos E, Nikas I, Blionas A, Sfakianos G, Themistocleous MS.
PMID: 29930870
Surg Neurol Int. 2018 May 24;9:104. doi: 10.4103/sni.sni_394_17. eCollection 2018.

BACKGROUND: Infratentorial subdural empyemas in children are extremely rare and potentially lethal intracranial infections. Delay in diagnosis and therapy is associated with increased morbidity and mortality.CASE DESCRIPTION: A 4-year-old boy presented with cerebellar signs following a failed treatment of...

Fetal subependymal giant cell astrocytoma: A case report and review of the literature.

Surgical neurology international

Karagianni A, Karydakis P, Giakoumettis D, Nikas I, Sfakianos G, Themistocleous M.
PMID: 32123614
Surg Neurol Int. 2020 Feb 25;11:26. doi: 10.25259/SNI_10_2019. eCollection 2020.

BACKGROUND: Subependymal giant cell astrocytomas (SEGAs) appear approximately in 10% of patients with tuberous sclerosis. These tumors are most commonly diagnosed in childhood and adolescence, with CASE DESCRIPTION: We present the case of a congenital SEGA detected in an...

Shape-Persistent Tetrahedral [4+6] Boronic Ester Cages with Different Degrees of Fluoride Substitution.

Chemistry (Weinheim an der Bergstrasse, Germany)

Elbert SM, Regenauer NI, Schindler D, Zhang WS, Rominger F, Schröder RR, Mastalerz M.
PMID: 29897652
Chemistry. 2018 Aug 06;24(44):11438-11443. doi: 10.1002/chem.201802123. Epub 2018 Jul 06.

In recent years the interest of shape-persistent organic cage compounds synthesized by dynamic covalent chemistry (DCC) has risen, because these cages are potentially interesting for gas sorption or -separation. One such reaction in DCC is the condensation of boronic...

Intraparenchymal Pericatheter Cyst after Cerebrospinal Fluid Shunt: A Rare Complication with Challenging Diagnosis - Case Presentation and Review of the Literature.

Asian journal of neurosurgery

Karydakis P, Nikas I, Panagopoulos D, Filippidou M, Sfakianos G, Themistocleous M.
PMID: 31143289
Asian J Neurosurg. 2019 Apr-Jun;14(2):581-584. doi: 10.4103/ajns.AJNS_288_18.

An intraparenchymal pericatheter cyst is a rare complication of ventriculoperitoneal shunt, which is not well described yet. Due to its rarity, lack of characteristic symptoms and radiological features that often mimic brain tumors or abscesses, especially in head computed...

Redox Activity of Iron Diazine-Diimine Carbonyl and Dinitrogen Complexes: A Comparative Study of the Influence of the Heterocyclic Ring.

Inorganic chemistry

Doll JS, Regenauer NI, Bothe VP, Wadepohl H, Roşca DA.
PMID: 34913670
Inorg Chem. 2022 Jan 10;61(1):520-532. doi: 10.1021/acs.inorgchem.1c03212. Epub 2021 Dec 16.

A detailed investigation of the electronic structure of diazinediimine iron complexes and their comparison with the pyridine analogues reveals subtle but important differences, imparted by the supporting heterocycle. In the case of LFe(CO)

Polyphenols and Novel Insights Into Post-kidney Transplant Complications and Cardiovascular Disease: A Narrative Review.

Frontiers in cardiovascular medicine

Bustos NI, Sotomayor CG, Pol RA, Navis GJ, Bakker SJL.
PMID: 34869655
Front Cardiovasc Med. 2021 Nov 16;8:751036. doi: 10.3389/fcvm.2021.751036. eCollection 2021.

Kidney transplantation is the preferred treatment for end-stage kidney disease. It is, however, not devoid of complications. Delayed graft function related to ischemia-reperfusion injury (IRI), calcineurin inhibitor (CNI) nephrotoxicity, diabetes, and a particularly high-rate cardiovascular disease (CVD) risk, represent...

Plasma Vitamin C and Risk of Late Graft Failure in Kidney Transplant Recipients: Results of the TransplantLines Biobank and Cohort Study.

Antioxidants (Basel, Switzerland)

Sotomayor CG, Bustos NI, Yepes-Calderon M, Arauna D, de Borst MH, Berger SP, Rodrigo R, Dullaart RPF, Navis GJ, Bakker SJL.
PMID: 33919075
Antioxidants (Basel). 2021 Apr 21;10(5). doi: 10.3390/antiox10050631.

Recent studies have shown that depletion of vitamin C is frequent in outpatient kidney transplant recipients (KTR) and that vitamin C is inversely associated with risk of death. Whether plasma vitamin C is associated with death-censored kidney graft failure...

Going deep into schizophrenia with artificial intelligence.

Schizophrenia research

Cortes-Briones JA, Tapia-Rivas NI, D'Souza DC, Estevez PA.
PMID: 34103242
Schizophr Res. 2021 Jun 05; doi: 10.1016/j.schres.2021.05.018. Epub 2021 Jun 05.

Despite years of research, the mechanisms governing the onset, relapse, symptomatology, and treatment of schizophrenia (SZ) remain elusive. The lack of appropriate analytic tools to deal with the heterogeneity and complexity of SZ may be one of the reasons...

Showing 1 to 12 of 46 entries