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Intermittent docetaxel chemotherapy is feasible for castration-resistant prostate cancer.

Molecular and clinical oncology

Kume H, Kawai T, Nagata M, Azuma T, Miyazaki H, Suzuki M, Fujimura T, Nakagawa T, Fukuhara H, Homma Y.
PMID: 25798258
Mol Clin Oncol. 2015 Mar;3(2):303-307. doi: 10.3892/mco.2014.469. Epub 2014 Dec 01.

This study was conducted with the aim to investigate the feasibility of intermittent treatment with docetaxel chemotherapy for castration-resistant prostate cancer (CRPC). A total of 51 men with CRPC received docetaxel at 75 mg/m

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Kume H, Kawai T, Nagata M, et al. Intermittent docetaxel chemotherapy is feasible for castration-resistant prostate cancer. Mol Clin Oncol. 2014;3(2):303-307doi: 10.3892/mco.2014.469.
Kume, H., Kawai, T., Nagata, M., Azuma, T., Miyazaki, H., Suzuki, M., Fujimura, T., Nakagawa, T., Fukuhara, H., & Homma, Y. (2015). Intermittent docetaxel chemotherapy is feasible for castration-resistant prostate cancer. Molecular and clinical oncology, 3(2), 303-307. https://doi.org/10.3892/mco.2014.469
Kume, Haruki, et al. "Intermittent docetaxel chemotherapy is feasible for castration-resistant prostate cancer." Molecular and clinical oncology vol. 3,2 (2015): 303-307. doi: https://doi.org/10.3892/mco.2014.469
Kume H, Kawai T, Nagata M, Azuma T, Miyazaki H, Suzuki M, Fujimura T, Nakagawa T, Fukuhara H, Homma Y. Intermittent docetaxel chemotherapy is feasible for castration-resistant prostate cancer. Mol Clin Oncol. 2015 Mar;3(2):303-307. doi: 10.3892/mco.2014.469. Epub 2014 Dec 01. PMID: 25798258; PMCID: PMC4360872.
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Evaluation of rifampicin resistance and 81-bp rifampicin resistant determinant region of rpoB gene mutations of Mycobacterium tuberculosis detected with XpertMTB/Rif in Cross River State, Nigeria.

International journal of mycobacteriology

Ochang EA, Udoh UA, Emanghe UE, Tiku GO, Offor JB, Odo M, Nkombe E, Owuna OE, Obeten SM, Meremikwu MM.
PMID: 28043515
Int J Mycobacteriol. 2016 Dec;5:S145-S146. doi: 10.1016/j.ijmyco.2016.09.007. Epub 2016 Oct 21.

OBJECTIVE/BACKGROUND: World Health Organization tuberculosis (TB) indices from 2014 to 2016 showed that Nigeria had the 6th highest prevalence, 4th highest incidence, and the highest mortality rate globally. In efforts to improve TB care, the XpertMTB/Rif (GeneXpert) technology, Cepheid,...

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Ochang EA, Udoh UA, Emanghe UE, et al. Evaluation of rifampicin resistance and 81-bp rifampicin resistant determinant region of rpoB gene mutations of Mycobacterium tuberculosis detected with XpertMTB/Rif in Cross River State, Nigeria. Int J Mycobacteriol. 2016;5:S145-S146doi: 10.1016/j.ijmyco.2016.09.007.
Ochang, E. A., Udoh, U. A., Emanghe, U. E., Tiku, G. O., Offor, J. B., Odo, M., Nkombe, E., Owuna, O. E., Obeten, S. M., & Meremikwu, M. M. (2016). Evaluation of rifampicin resistance and 81-bp rifampicin resistant determinant region of rpoB gene mutations of Mycobacterium tuberculosis detected with XpertMTB/Rif in Cross River State, Nigeria. International journal of mycobacteriology, 5S145-S146. https://doi.org/10.1016/j.ijmyco.2016.09.007
Ochang, Ernest A, et al. "Evaluation of rifampicin resistance and 81-bp rifampicin resistant determinant region of rpoB gene mutations of Mycobacterium tuberculosis detected with XpertMTB/Rif in Cross River State, Nigeria." International journal of mycobacteriology vol. 5 (2016): S145-S146. doi: https://doi.org/10.1016/j.ijmyco.2016.09.007
Ochang EA, Udoh UA, Emanghe UE, Tiku GO, Offor JB, Odo M, Nkombe E, Owuna OE, Obeten SM, Meremikwu MM. Evaluation of rifampicin resistance and 81-bp rifampicin resistant determinant region of rpoB gene mutations of Mycobacterium tuberculosis detected with XpertMTB/Rif in Cross River State, Nigeria. Int J Mycobacteriol. 2016 Dec;5:S145-S146. doi: 10.1016/j.ijmyco.2016.09.007. Epub 2016 Oct 21. PMID: 28043515.
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Neuronal β-amyloid generation is independent of lipid raft association of β-secretase BACE1: analysis with a palmitoylation-deficient mutant.

Brain and behavior

Motoki K, Kume H, Oda A, Tamaoka A, Hosaka A, Kametani F, Araki W.
PMID: 22741101
Brain Behav. 2012 May;2(3):270-82. doi: 10.1002/brb3.52.

β-Secretase, BACE1 is a neuron-specific membrane-associated protease that cleaves amyloid precursor protein (APP) to generate β-amyloid protein (Aβ). BACE1 is partially localized in lipid rafts. We investigated whether lipid raft localization of BACE1 affects Aβ production in neurons using...

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Motoki K, Kume H, Oda A, et al. Neuronal β-amyloid generation is independent of lipid raft association of β-secretase BACE1: analysis with a palmitoylation-deficient mutant. Brain Behav. 2012;2(3):270-82doi: 10.1002/brb3.52.
Motoki, K., Kume, H., Oda, A., Tamaoka, A., Hosaka, A., Kametani, F., & Araki, W. (2012). Neuronal β-amyloid generation is independent of lipid raft association of β-secretase BACE1: analysis with a palmitoylation-deficient mutant. Brain and behavior, 2(3), 270-82. https://doi.org/10.1002/brb3.52
Motoki, Kazumi, et al. "Neuronal β-amyloid generation is independent of lipid raft association of β-secretase BACE1: analysis with a palmitoylation-deficient mutant." Brain and behavior vol. 2,3 (2012): 270-82. doi: https://doi.org/10.1002/brb3.52
Motoki K, Kume H, Oda A, Tamaoka A, Hosaka A, Kametani F, Araki W. Neuronal β-amyloid generation is independent of lipid raft association of β-secretase BACE1: analysis with a palmitoylation-deficient mutant. Brain Behav. 2012 May;2(3):270-82. doi: 10.1002/brb3.52. PMID: 22741101; PMCID: PMC3381632.
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Donations: how to ensure you really benefit.

Community eye health

Cordero I, Murray N, Nkumbe HE.
PMID: 21119920
Community Eye Health. 2010 Sep;23(73):32-3.

No abstract available.

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Cordero I, Murray N, Nkumbe HE. Donations: how to ensure you really benefit. Community Eye Health. 2010;23(73):32-3
Cordero, I., Murray, N., & Nkumbe, H. E. (2010). Donations: how to ensure you really benefit. Community eye health, 23(73), 32-3.
Cordero, Ismael, et al. "Donations: how to ensure you really benefit." Community eye health vol. 23,73 (2010): 32-3.
Cordero I, Murray N, Nkumbe HE. Donations: how to ensure you really benefit. Community Eye Health. 2010 Sep;23(73):32-3. PMID: 21119920; PMCID: PMC2975117.
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High expression of heat shock protein 105 predicts a favorable prognosis for patients with urinary bladder cancer treated with radical cystectomy.

Molecular and clinical oncology

Kawai T, Enomoto Y, Morikawa T, Matsushita H, Kume H, Fukayama M, Yamaguchi H, Kakimi K, Homma Y.
PMID: 24649305
Mol Clin Oncol. 2014 Jan;2(1):38-42. doi: 10.3892/mco.2013.203. Epub 2013 Oct 18.

Heat shock protein 105 (Hsp105) is one of the cancer/testis antigens, which is overexpressed in a variety of cancer cells, including urinary bladder cancer, and has been investigated as a target molecule for immunotherapy due to its immunogenicity. In...

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Kawai T, Enomoto Y, Morikawa T, et al. High expression of heat shock protein 105 predicts a favorable prognosis for patients with urinary bladder cancer treated with radical cystectomy. Mol Clin Oncol. 2013;2(1):38-42doi: 10.3892/mco.2013.203.
Kawai, T., Enomoto, Y., Morikawa, T., Matsushita, H., Kume, H., Fukayama, M., Yamaguchi, H., Kakimi, K., & Homma, Y. (2014). High expression of heat shock protein 105 predicts a favorable prognosis for patients with urinary bladder cancer treated with radical cystectomy. Molecular and clinical oncology, 2(1), 38-42. https://doi.org/10.3892/mco.2013.203
Kawai, Taketo, et al. "High expression of heat shock protein 105 predicts a favorable prognosis for patients with urinary bladder cancer treated with radical cystectomy." Molecular and clinical oncology vol. 2,1 (2014): 38-42. doi: https://doi.org/10.3892/mco.2013.203
Kawai T, Enomoto Y, Morikawa T, Matsushita H, Kume H, Fukayama M, Yamaguchi H, Kakimi K, Homma Y. High expression of heat shock protein 105 predicts a favorable prognosis for patients with urinary bladder cancer treated with radical cystectomy. Mol Clin Oncol. 2014 Jan;2(1):38-42. doi: 10.3892/mco.2013.203. Epub 2013 Oct 18. PMID: 24649305; PMCID: PMC3915630.
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Elucidation of the molecular mechanisms underlying adverse reactions associated with a kinase inhibitor using systems toxicology.

NPJ systems biology and applications

Amemiya T, Honma M, Kariya Y, Ghosh S, Kitano H, Kurachi Y, Fujita KI, Sasaki Y, Homma Y, Abernethy DR, Kume H, Suzuki H.
PMID: 28725458
NPJ Syst Biol Appl. 2015 Sep 28;1:15005. doi: 10.1038/npjsba.2015.5. eCollection 2015.

CONCLUSIONS: A systems toxicological approach successfully predicted the molecular mechanisms underlying clinically adverse reactions associated with sunitinib and was used to plan a rational method for the management of these adverse reactions.

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Amemiya T, Honma M, Kariya Y, et al. Elucidation of the molecular mechanisms underlying adverse reactions associated with a kinase inhibitor using systems toxicology. NPJ Syst Biol Appl. 2015;1:15005doi: 10.1038/npjsba.2015.5.
Amemiya, T., Honma, M., Kariya, Y., Ghosh, S., Kitano, H., Kurachi, Y., Fujita, K. I., Sasaki, Y., Homma, Y., Abernethy, D. R., Kume, H., & Suzuki, H. (2015). Elucidation of the molecular mechanisms underlying adverse reactions associated with a kinase inhibitor using systems toxicology. NPJ systems biology and applications, 115005. https://doi.org/10.1038/npjsba.2015.5
Amemiya, Takahiro, et al. "Elucidation of the molecular mechanisms underlying adverse reactions associated with a kinase inhibitor using systems toxicology." NPJ systems biology and applications vol. 1 (2015): 15005. doi: https://doi.org/10.1038/npjsba.2015.5
Amemiya T, Honma M, Kariya Y, Ghosh S, Kitano H, Kurachi Y, Fujita KI, Sasaki Y, Homma Y, Abernethy DR, Kume H, Suzuki H. Elucidation of the molecular mechanisms underlying adverse reactions associated with a kinase inhibitor using systems toxicology. NPJ Syst Biol Appl. 2015 Sep 28;1:15005. doi: 10.1038/npjsba.2015.5. eCollection 2015. PMID: 28725458; PMCID: PMC5516806.
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Development of a multi-channel 320 GHz interferometer for high density plasma measurement in Heliotron J.

The Review of scientific instruments

Ohshima S, Zhang P, Kume H, Deng C, Miyashita A, Kobayashi S, Okada H, Minami T, Kado S, Adulsiriswad P, Qiu D, Luo M, Matoike R, Suzuki T, Konoshima S, Mizuuchi T, Nagasaki K.
PMID: 34243360
Rev Sci Instrum. 2021 May 01;92(5):053519. doi: 10.1063/5.0043581.

We report the development of a new interferometer with two stable, high-power, 320 GHz solid-state sources in Heliotron J. A heterodyne Michelson interferometer optical scheme is employed. Two solid-state oscillators are utilized as sources with a fixed frequency at...

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Ohshima S, Zhang P, Kume H, et al. Development of a multi-channel 320 GHz interferometer for high density plasma measurement in Heliotron J. Rev Sci Instrum. 2021;92(5):053519doi: 10.1063/5.0043581.
Ohshima, S., Zhang, P., Kume, H., Deng, C., Miyashita, A., Kobayashi, S., Okada, H., Minami, T., Kado, S., Adulsiriswad, P., Qiu, D., Luo, M., Matoike, R., Suzuki, T., Konoshima, S., Mizuuchi, T., & Nagasaki, K. (2021). Development of a multi-channel 320 GHz interferometer for high density plasma measurement in Heliotron J. The Review of scientific instruments, 92(5), 053519. https://doi.org/10.1063/5.0043581
Ohshima, S, et al. "Development of a multi-channel 320 GHz interferometer for high density plasma measurement in Heliotron J." The Review of scientific instruments vol. 92,5 (2021): 053519. doi: https://doi.org/10.1063/5.0043581
Ohshima S, Zhang P, Kume H, Deng C, Miyashita A, Kobayashi S, Okada H, Minami T, Kado S, Adulsiriswad P, Qiu D, Luo M, Matoike R, Suzuki T, Konoshima S, Mizuuchi T, Nagasaki K. Development of a multi-channel 320 GHz interferometer for high density plasma measurement in Heliotron J. Rev Sci Instrum. 2021 May 01;92(5):053519. doi: 10.1063/5.0043581. PMID: 34243360.
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Helping older people get the eye care they need.

Community eye health

Nkumbe H.
PMID: 18670599
Community Eye Health. 2008 Jun;21(66):26-8.

No abstract available.

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Nkumbe H. Helping older people get the eye care they need. Community Eye Health. 2008;21(66):26-8
Nkumbe, H. (2008). Helping older people get the eye care they need. Community eye health, 21(66), 26-8.
Nkumbe, Henry. "Helping older people get the eye care they need." Community eye health vol. 21,66 (2008): 26-8.
Nkumbe H. Helping older people get the eye care they need. Community Eye Health. 2008 Jun;21(66):26-8. PMID: 18670599; PMCID: PMC2467467.
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Molecular classification and diagnostics of upper urinary tract urothelial carcinoma.

Cancer cell

Fujii Y, Sato Y, Suzuki H, Kakiuchi N, Yoshizato T, Lenis AT, Maekawa S, Yokoyama A, Takeuchi Y, Inoue Y, Ochi Y, Shiozawa Y, Aoki K, Yoshida K, Kataoka K, Nakagawa MM, Nannya Y, Makishima H, Miyakawa J, Kawai T, Morikawa T, Shiraishi Y, Chiba K, Tanaka H, Nagae G, Sanada M, Sugihara E, Sato TA, Nakagawa T, Fukayama M, Ushiku T, Aburatani H, Miyano S, Coleman JA, Homma Y, Solit DB, Kume H, Ogawa S.
PMID: 34129823
Cancer Cell. 2021 Jun 14;39(6):793-809.e8. doi: 10.1016/j.ccell.2021.05.008.

Upper urinary tract urothelial carcinoma (UTUC) is one of the common urothelial cancers. Its molecular pathogenesis, however, is poorly understood, with no useful biomarkers available for accurate diagnosis and molecular classification. Through an integrated genetic study involving 199 UTUC...

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Fujii Y, Sato Y, Suzuki H, et al. Molecular classification and diagnostics of upper urinary tract urothelial carcinoma. Cancer Cell. 2021;39(6):793-809.e8doi: 10.1016/j.ccell.2021.05.008.
Fujii, Y., Sato, Y., Suzuki, H., Kakiuchi, N., Yoshizato, T., Lenis, A. T., Maekawa, S., Yokoyama, A., Takeuchi, Y., Inoue, Y., Ochi, Y., Shiozawa, Y., Aoki, K., Yoshida, K., Kataoka, K., Nakagawa, M. M., Nannya, Y., Makishima, H., Miyakawa, J., Kawai, T., Morikawa, T., Shiraishi, Y., Chiba, K., Tanaka, H., Nagae, G., Sanada, M., Sugihara, E., Sato, T. A., Nakagawa, T., Fukayama, M., Ushiku, T., Aburatani, H., Miyano, S., Coleman, J. A., Homma, Y., Solit, D. B., Kume, H., & Ogawa, S. (2021). Molecular classification and diagnostics of upper urinary tract urothelial carcinoma. Cancer cell, 39(6), 793-809.e8. https://doi.org/10.1016/j.ccell.2021.05.008
Fujii, Yoichi, et al. "Molecular classification and diagnostics of upper urinary tract urothelial carcinoma." Cancer cell vol. 39,6 (2021): 793-809.e8. doi: https://doi.org/10.1016/j.ccell.2021.05.008
Fujii Y, Sato Y, Suzuki H, Kakiuchi N, Yoshizato T, Lenis AT, Maekawa S, Yokoyama A, Takeuchi Y, Inoue Y, Ochi Y, Shiozawa Y, Aoki K, Yoshida K, Kataoka K, Nakagawa MM, Nannya Y, Makishima H, Miyakawa J, Kawai T, Morikawa T, Shiraishi Y, Chiba K, Tanaka H, Nagae G, Sanada M, Sugihara E, Sato TA, Nakagawa T, Fukayama M, Ushiku T, Aburatani H, Miyano S, Coleman JA, Homma Y, Solit DB, Kume H, Ogawa S. Molecular classification and diagnostics of upper urinary tract urothelial carcinoma. Cancer Cell. 2021 Jun 14;39(6):793-809.e8. doi: 10.1016/j.ccell.2021.05.008. PMID: 34129823.
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A case report of intersigmoid hernia treated using laparoscopic surgery.

International journal of surgery case reports

Kambe H, Kitamura K, Kaihara S.
PMID: 33887854
Int J Surg Case Rep. 2021 Apr;81:105822. doi: 10.1016/j.ijscr.2021.105822. Epub 2021 Mar 26.

INTRODUCTION AND IMPORTANCE: Intersigmoid hernia (ISH) is a rare disease that is difficult to diagnose preoperatively and sometimes causes intestinal necrosis that requires emergency surgery.CASE PRESENTATION: The patient was an 87-year-old male with no history of abdominal surgery who...

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Kambe H, Kitamura K, Kaihara S. A case report of intersigmoid hernia treated using laparoscopic surgery. Int J Surg Case Rep. 2021;81:105822doi: 10.1016/j.ijscr.2021.105822.
Kambe, H., Kitamura, K., & Kaihara, S. (2021). A case report of intersigmoid hernia treated using laparoscopic surgery. International journal of surgery case reports, 81105822. https://doi.org/10.1016/j.ijscr.2021.105822
Kambe, Hiroyuki, et al. "A case report of intersigmoid hernia treated using laparoscopic surgery." International journal of surgery case reports vol. 81 (2021): 105822. doi: https://doi.org/10.1016/j.ijscr.2021.105822
Kambe H, Kitamura K, Kaihara S. A case report of intersigmoid hernia treated using laparoscopic surgery. Int J Surg Case Rep. 2021 Apr;81:105822. doi: 10.1016/j.ijscr.2021.105822. Epub 2021 Mar 26. PMID: 33887854; PMCID: PMC8049999.
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Clinicopathological features and oncological outcomes of urothelial carcinoma involving the ureterovesical junction.

Japanese journal of clinical oncology

Oshina T, Taguchi S, Miyakawa J, Akiyama Y, Sato Y, Kawai T, Fukuhara H, Nakagawa T, Kume H.
PMID: 34510192
Jpn J Clin Oncol. 2021 Sep 11; doi: 10.1093/jjco/hyab143. Epub 2021 Sep 11.

BACKGROUND: The ureterovesical junction is the boundary between the urinary bladder and upper urinary tract. Because treatment strategies for bladder cancer and upper tract urothelial carcinoma are entirely different, urothelial carcinoma involving the ureterovesical junction requires special attention. Nevertheless,...

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Oshina T, Taguchi S, Miyakawa J, et al. Clinicopathological features and oncological outcomes of urothelial carcinoma involving the ureterovesical junction. Jpn J Clin Oncol. 2021;doi: 10.1093/jjco/hyab143.
Oshina, T., Taguchi, S., Miyakawa, J., Akiyama, Y., Sato, Y., Kawai, T., Fukuhara, H., Nakagawa, T., & Kume, H. (2021). Clinicopathological features and oncological outcomes of urothelial carcinoma involving the ureterovesical junction. Japanese journal of clinical oncology, . https://doi.org/10.1093/jjco/hyab143
Oshina, Takahiro, et al. "Clinicopathological features and oncological outcomes of urothelial carcinoma involving the ureterovesical junction." Japanese journal of clinical oncology vol. (2021). doi: https://doi.org/10.1093/jjco/hyab143
Oshina T, Taguchi S, Miyakawa J, Akiyama Y, Sato Y, Kawai T, Fukuhara H, Nakagawa T, Kume H. Clinicopathological features and oncological outcomes of urothelial carcinoma involving the ureterovesical junction. Jpn J Clin Oncol. 2021 Sep 11; doi: 10.1093/jjco/hyab143. Epub 2021 Sep 11. PMID: 34510192.
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Corrigendum to: Perinephric invasion as a prognostic factor in non-metastatic renal cell carcinoma: analysis of a nation-wide registry program.

Japanese journal of clinical oncology

Kume H, Homma Y, Shinohara N, Obara W, Kondo T, Kimura G, Fujimoto H, Nonomura N, Hongo F, Sugiyama T, Takahashi M, Kanayama HO, Fukumori T, Eto M.
PMID: 31693139
Jpn J Clin Oncol. 2019 Dec 18;49(11):1067. doi: 10.1093/jjco/hyz143.

No abstract available.

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Kume H, Homma Y, Shinohara N, et al. Corrigendum to: Perinephric invasion as a prognostic factor in non-metastatic renal cell carcinoma: analysis of a nation-wide registry program. Jpn J Clin Oncol. 2019;49(11):1067doi: 10.1093/jjco/hyz143.
Kume, H., Homma, Y., Shinohara, N., Obara, W., Kondo, T., Kimura, G., Fujimoto, H., Nonomura, N., Hongo, F., Sugiyama, T., Takahashi, M., Kanayama, H. O., Fukumori, T., & Eto, M. (2019). Corrigendum to: Perinephric invasion as a prognostic factor in non-metastatic renal cell carcinoma: analysis of a nation-wide registry program. Japanese journal of clinical oncology, 49(11), 1067. https://doi.org/10.1093/jjco/hyz143
Kume, Haruki, et al. "Corrigendum to: Perinephric invasion as a prognostic factor in non-metastatic renal cell carcinoma: analysis of a nation-wide registry program." Japanese journal of clinical oncology vol. 49,11 (2019): 1067. doi: https://doi.org/10.1093/jjco/hyz143
Kume H, Homma Y, Shinohara N, Obara W, Kondo T, Kimura G, Fujimoto H, Nonomura N, Hongo F, Sugiyama T, Takahashi M, Kanayama HO, Fukumori T, Eto M. Corrigendum to: Perinephric invasion as a prognostic factor in non-metastatic renal cell carcinoma: analysis of a nation-wide registry program. Jpn J Clin Oncol. 2019 Dec 18;49(11):1067. doi: 10.1093/jjco/hyz143. PMID: 31693139.
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Showing 1 to 12 of 76 entries