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Showing 1 to 12 of 59 entries
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Impact of the number of mutations in survival and response outcomes to hypomethylating agents in patients with myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms.

Oncotarget

Montalban-Bravo G, Takahashi K, Patel K, Wang F, Xingzhi S, Nogueras GM, Huang X, Pierola AA, Jabbour E, Colla S, Gañan-Gomez I, Borthakur G, Daver N, Estrov Z, Kadia T, Pemmaraju N, Ravandi F, Bueso-Ramos C, Chamseddine A, Konopleva M, Zhang J, Kantarjian H, Futreal A, Garcia-Manero G.
PMID: 29515765
Oncotarget. 2018 Jan 03;9(11):9714-9727. doi: 10.18632/oncotarget.23882. eCollection 2018 Feb 09.

The prognostic and predictive value of sequencing analysis in myelodysplastic syndromes (MDS) has not been fully integrated into clinical practice. We performed whole exome sequencing (WES) of bone marrow samples from 83 patients with MDS and 31 with MDS/MPN...

5,5-Dimethyl-3-(5-methyl-1H-pyrazol-3-ylamino)cyclohex-3-en-1-one.

Acta crystallographica. Section C, Crystal structure communications

Quiroga J, Insuasty B, Abonia R, Mejia D, Cobo J, Nogueras M, Sanchez A, Low JN.
PMID: 11118988
Acta Crystallogr C. 2000 Dec;56:1457-9. doi: 10.1107/s0108270100012300.

The molecules of the title compound, C(12)H(17)N(3)O, are linked by two N-H.O hydrogen bonds to form a three-dimensional network. The N. O distances are 2.804 (3) and 2.766 (3) A, both involving a common acceptor O atom.

Ethyl N-(2-benzylamino-6-benzyloxy-5-nitrosopyrimidin-4-yl)glycinate: sheets built from a three-centre N[bond]H...(N,O), and two-centre C[bond]H...O and C[bond]H...pi(arene) hydrogen bonds.

Acta crystallographica. Section C, Crystal structure communications

Low JN, Glidewell C, Quesada A, Nogueras M, Sánchez A.
PMID: 12094066
Acta Crystallogr C. 2002 Jul;58:o425-7. doi: 10.1107/s0108270102009575. Epub 2002 Jun 20.

In the title compound, C(22)H(23)N(5)O(4), the molecules are linked into chains by a three-centre N[bond]H...(N,O) hydrogen bond, reinforced by a two-centre C[bond]H...O hydrogen bond, and the chains are further linked into sheets by a combination of C[bond]H...O and C[bond]H...pi(arene)...

4-(allylamino)-2-amino-6-benzyloxy-5-nitrosopyrimidine from synchrotron data at 150 K: double chains built from N[bond]H...N, N[bond]H...O, N[bond]H...pi(arene) and aromatic pi-pi-stacking interactions.

Acta crystallographica. Section C, Crystal structure communications

MacLean EJ, Low JN, Quesada A, Melguizo M, Nogueras M, Glidewell C.
PMID: 12094072
Acta Crystallogr C. 2002 Jul;58:o442-4. doi: 10.1107/s0108270102010387. Epub 2002 Jun 29.

In the title compound, C(14)H(15)N(5)O(2), the intramolecular dimensions are consistent with a highly polarized electronic structure. The molecules are linked into chains by a combination of N[bond]H...N, N[bond]H...O and N[bond]H...pi(arene) hydrogen bonds, and the chains are linked in pairs...

5-[N-(1H-Benzotriazol-1-ylmethyl)amino]-3-tert-butyl-1-phenylpyrazole: sheets built from N[bond]H...N, C[bond]H...N and C[bond]H...pi(pyrazole) interactions.

Acta crystallographica. Section C, Crystal structure communications

Glidewell C, Low JN, Cobo J, Nogueras M, Sánchez A, Rengifo E, Abonia R.
PMID: 12050426
Acta Crystallogr C. 2002 Jun;58:o314-7. doi: 10.1107/s0108270102006881. Epub 2002 May 11.

In the title compound, C(20)H(22)N(6), the molecules are linked into a chain of rings by N[bond]H...N [H...N 2.16 A, N...N 2.950 (3) A and N[bond]H...N 149 degrees] and C[bond]H...N [H...N 2.55 A, C...N 3.481 (3) A and C[bond]H...N 165...

Effect of age on the functional outcome of total abdominal colectomy for colonic inertia.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Pikarsky AJ, Efron J, Hamel CT, Weiss EG, Nogueras JJ, Wexner SD.
PMID: 12790953
Colorectal Dis. 2001 Sep;3(5):318-22. doi: 10.1046/j.1463-1318.2001.00259.x.

OBJECTIVE: Colonic inertia (CI) usually presents in women in the third decade of life; however, elderly patients are at times diagnosed with the disease. Total abdominal colectomy (TAC) is considered the preferred surgical treatment for patients with well established...

Layer-by-layer deposited chitosan/silk fibroin thin films with anisotropic nanofiber alignment.

Langmuir : the ACS journal of surfaces and colloids

Nogueira GM, Swiston AJ, Beppu MM, Rubner MF.
PMID: 20158176
Langmuir. 2010 Jun 01;26(11):8953-8. doi: 10.1021/la904741h.

Chitosan/silk fibroin multilayer thin films were assembled using layer-by-layer deposition. The resultant multilayer films contained nanofibers aligned parallel to the dipping direction. Fiber deposition and orientation was enabled uniquely by a judicious choice of solvent and drying conditions and...

Slow transit constipation: a review of a colonic functional disorder.

Clinics in colon and rectal surgery

Frattini JC, Nogueras JJ.
PMID: 20011411
Clin Colon Rectal Surg. 2008 May;21(2):146-52. doi: 10.1055/s-2008-1075864.

Constipation is a common gastrointestinal complaint that can cause significant physical and psychosocial problems. It has been categorized as slow transit constipation, normal transit constipation, and obstructed defecation. Both the definition and pathophysiology of constipation are unclear, but attempts...

Bats from different foraging guilds prey upon the pine processionary moth.

PeerJ

Garin I, Aihartza J, Goiti U, Arrizabalaga-Escudero A, Nogueras J, Ibáñez C.
PMID: 31316870
PeerJ. 2019 Jul 05;7:e7169. doi: 10.7717/peerj.7169. eCollection 2019.

Outbreaks of the processionary moth

A PROPRIETARY GMP HUMAN PLATELET LYSATE FOR THE EXPANSION OF DERMAL FIBROBLASTS FOR CLINICAL APPLICATIONS.

Platelets

Fernández Muñoz B, Lopez-Navas L, Gonzalez Bermejo M, Lomas Romero IM, Montiel Aguilera MÁ, Campos Cuerva R, Arribas Arribas B, Nogueras S, Carmona Sánchez G, Santos González M.
PMID: 33393414
Platelets. 2021 Jan 03;1-12. doi: 10.1080/09537104.2020.1856356. Epub 2021 Jan 03.

Recent years have witnessed the introduction of

COVID-19 in dialysis units: A comprehensive review.

World journal of virology

Nogueira GM, Oliveira MS, Moura AF, Cruz CMS, Moura-Neto JA.
PMID: 34631476
World J Virol. 2021 Sep 25;10(5):264-274. doi: 10.5501/wjv.v10.i5.264.

The coronavirus disease 2019 (COVID-19) pandemic has been challenging for healthcare professionals worldwide. One of the populations affected by the pandemic are patients on renal replacement therapy, as kidney disease is an independent risk factor for severe COVID-19 and...

Peptide-Functionalized Dendrimer Nanocarriers for Targeted Microdystrophin Gene Delivery.

Pharmaceutics

Hersh J, Condor Capcha JM, Iansen Irion C, Lambert G, Noguera M, Singh M, Kaur A, Dikici E, Jiménez JJ, Shehadeh LA, Daunert S, Deo SK.
PMID: 34959441
Pharmaceutics. 2021 Dec 15;13(12). doi: 10.3390/pharmaceutics13122159.

Gene therapy is a good alternative for determined congenital disorders; however, there are numerous limitations for gene delivery in vivo including targeted cellular uptake, intracellular trafficking, and transport through the nuclear membrane. Here, a modified G5 polyamidoamine (G5 PAMAM)...

Showing 1 to 12 of 59 entries