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Could Non-contrast 3DCT-Venography Be the First-Choice Diagnostic Imaging Modality for the Treatment of Varicose Vein?.

Annals of vascular diseases

Takahashi Y, Kokubo M, Nozaka T.
PMID: 27087867
Ann Vasc Dis. 2016;9(1):8-14. doi: 10.3400/avd.oa.15-00132. Epub 2016 Jan 25.

We investigated whether non-contrast three-dimensional computed tomography-venography (3DCTV) using 128-row multidetector computed tomography (MDCT) could be the first-choice diagnostic imaging modality for the treatment of varicose veins. Its utility was assessed in terms of estimation of the venous function,...

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Takahashi Y, Kokubo M, Nozaka T. Could Non-contrast 3DCT-Venography Be the First-Choice Diagnostic Imaging Modality for the Treatment of Varicose Vein?. Ann Vasc Dis. 2016;9(1):8-14doi: 10.3400/avd.oa.15-00132.
Takahashi, Y., Kokubo, M., & Nozaka, T. (2016). Could Non-contrast 3DCT-Venography Be the First-Choice Diagnostic Imaging Modality for the Treatment of Varicose Vein?. Annals of vascular diseases, 9(1), 8-14. https://doi.org/10.3400/avd.oa.15-00132
Takahashi, Yoshifumi, et al. "Could Non-contrast 3DCT-Venography Be the First-Choice Diagnostic Imaging Modality for the Treatment of Varicose Vein?." Annals of vascular diseases vol. 9,1 (2016): 8-14. doi: https://doi.org/10.3400/avd.oa.15-00132
Takahashi Y, Kokubo M, Nozaka T. Could Non-contrast 3DCT-Venography Be the First-Choice Diagnostic Imaging Modality for the Treatment of Varicose Vein?. Ann Vasc Dis. 2016;9(1):8-14. doi: 10.3400/avd.oa.15-00132. Epub 2016 Jan 25. PMID: 27087867; PMCID: PMC4807209.
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Hetero Bis-Addition of Spiro-Acetalized or Cyclohexanone Ring to 58π Fullerene Impacts Solubility and Mobility Balance in Polymer Solar Cells.

ACS applied materials & interfaces

Mikie T, Saeki A, Ikuma N, Kokubo K, Seki S.
PMID: 26010767
ACS Appl Mater Interfaces. 2015 Jun 17;7(23):12894-902. doi: 10.1021/acsami.5b02456. Epub 2015 Jun 08.

Fullerene bis-adducts are increasingly being studied to gain a high open circuit voltage (Voc) in bulk heterojunction organic photovoltaics (OPVs). We designed and synthesized homo and hetero bis-adduct [60]fullerenes by combining fused cyclohexanone or a five-membered spiro-acetalized unit (SAF5)...

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Mikie T, Saeki A, Ikuma N, et al. Hetero Bis-Addition of Spiro-Acetalized or Cyclohexanone Ring to 58π Fullerene Impacts Solubility and Mobility Balance in Polymer Solar Cells. ACS Appl Mater Interfaces. 2015;7(23):12894-902doi: 10.1021/acsami.5b02456.
Mikie, T., Saeki, A., Ikuma, N., Kokubo, K., & Seki, S. (2015). Hetero Bis-Addition of Spiro-Acetalized or Cyclohexanone Ring to 58π Fullerene Impacts Solubility and Mobility Balance in Polymer Solar Cells. ACS applied materials & interfaces, 7(23), 12894-902. https://doi.org/10.1021/acsami.5b02456
Mikie, Tsubasa, et al. "Hetero Bis-Addition of Spiro-Acetalized or Cyclohexanone Ring to 58π Fullerene Impacts Solubility and Mobility Balance in Polymer Solar Cells." ACS applied materials & interfaces vol. 7,23 (2015): 12894-902. doi: https://doi.org/10.1021/acsami.5b02456
Mikie T, Saeki A, Ikuma N, Kokubo K, Seki S. Hetero Bis-Addition of Spiro-Acetalized or Cyclohexanone Ring to 58π Fullerene Impacts Solubility and Mobility Balance in Polymer Solar Cells. ACS Appl Mater Interfaces. 2015 Jun 17;7(23):12894-902. doi: 10.1021/acsami.5b02456. Epub 2015 Jun 08. PMID: 26010767.
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Preparation of stimuli-responsive "mushroom-like" janus polymer particles as particulate surfactant by site-selective surface-initiated AGET ATRP in aqueous dispersed systems.

Langmuir : the ACS journal of surfaces and colloids

Yamagami T, Kitayama Y, Okubo M.
PMID: 24934829
Langmuir. 2014 Jul 08;30(26):7823-32. doi: 10.1021/la501266t. Epub 2014 Jun 26.

Micrometer-sized, monodisperse, "mushroom-like" Janus poly(methyl methacrylate)/poly(styrene-2-(2-bromoisobutyryloxy)ethyl methacrylate)-graft-poly(2-(dimethyl amino)ethyl methacrylate) (PMMA/P(S-BIEM)-g-PDM) particles were successfully synthesized by site-selective surface-initiated activator generated by electron transfer for atom transfer radical polymerization in aqueous dispersed systems with spherical PMMA/P(S-BIEM) composite particles having controlled morphologies...

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Yamagami T, Kitayama Y, Okubo M. Preparation of stimuli-responsive "mushroom-like" janus polymer particles as particulate surfactant by site-selective surface-initiated AGET ATRP in aqueous dispersed systems. Langmuir. 2014;30(26):7823-32doi: 10.1021/la501266t.
Yamagami, T., Kitayama, Y., & Okubo, M. (2014). Preparation of stimuli-responsive "mushroom-like" janus polymer particles as particulate surfactant by site-selective surface-initiated AGET ATRP in aqueous dispersed systems. Langmuir : the ACS journal of surfaces and colloids, 30(26), 7823-32. https://doi.org/10.1021/la501266t
Yamagami, Tomoe, et al. "Preparation of stimuli-responsive "mushroom-like" janus polymer particles as particulate surfactant by site-selective surface-initiated AGET ATRP in aqueous dispersed systems." Langmuir : the ACS journal of surfaces and colloids vol. 30,26 (2014): 7823-32. doi: https://doi.org/10.1021/la501266t
Yamagami T, Kitayama Y, Okubo M. Preparation of stimuli-responsive "mushroom-like" janus polymer particles as particulate surfactant by site-selective surface-initiated AGET ATRP in aqueous dispersed systems. Langmuir. 2014 Jul 08;30(26):7823-32. doi: 10.1021/la501266t. Epub 2014 Jun 26. PMID: 24934829.
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Kinetic study of the Diels-Alder reaction of Li⁺@C₆₀ with cyclohexadiene: greatly increased reaction rate by encapsulated Li⁺.

Journal of the American Chemical Society

Ueno H, Kawakami H, Nakagawa K, Okada H, Ikuma N, Aoyagi S, Kokubo K, Matsuo Y, Oshima T.
PMID: 25006694
J Am Chem Soc. 2014 Aug 06;136(31):11162-7. doi: 10.1021/ja505952y. Epub 2014 Jul 23.

We studied the kinetics of the Diels-Alder reaction of Li(+)-encapsulated [60]fullerene with 1,3-cyclohexadiene and characterized the obtained product, [Li(+)@C60(C6H8)](PF6(-)). Compared with empty C60, Li(+)@C60 reacted 2400-fold faster at 303 K, a rate enhancement that corresponds to lowering the activation...

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Ueno H, Kawakami H, Nakagawa K, et al. Kinetic study of the Diels-Alder reaction of Li⁺@C₆₀ with cyclohexadiene: greatly increased reaction rate by encapsulated Li⁺. J Am Chem Soc. 2014;136(31):11162-7doi: 10.1021/ja505952y.
Ueno, H., Kawakami, H., Nakagawa, K., Okada, H., Ikuma, N., Aoyagi, S., Kokubo, K., Matsuo, Y., & Oshima, T. (2014). Kinetic study of the Diels-Alder reaction of Li⁺@C₆₀ with cyclohexadiene: greatly increased reaction rate by encapsulated Li⁺. Journal of the American Chemical Society, 136(31), 11162-7. https://doi.org/10.1021/ja505952y
Ueno, Hiroshi, et al. "Kinetic study of the Diels-Alder reaction of Li⁺@C₆₀ with cyclohexadiene: greatly increased reaction rate by encapsulated Li⁺." Journal of the American Chemical Society vol. 136,31 (2014): 11162-7. doi: https://doi.org/10.1021/ja505952y
Ueno H, Kawakami H, Nakagawa K, Okada H, Ikuma N, Aoyagi S, Kokubo K, Matsuo Y, Oshima T. Kinetic study of the Diels-Alder reaction of Li⁺@C₆₀ with cyclohexadiene: greatly increased reaction rate by encapsulated Li⁺. J Am Chem Soc. 2014 Aug 06;136(31):11162-7. doi: 10.1021/ja505952y. Epub 2014 Jul 23. PMID: 25006694.
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Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells.

Nature communications

Kato Y, Katsuki T, Kokubo H, Masuda A, Saga Y.
PMID: 27072294
Nat Commun. 2016 Apr 13;7:11272. doi: 10.1038/ncomms11272.

Evolutionally conserved Nanos RNA-binding proteins play crucial roles in germ cell development. While a mammalian Nanos family protein, NANOS2, is required for sexual differentiation of male (XY) germ cells in mice, the underlying mechanisms and the identities of its...

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Kato Y, Katsuki T, Kokubo H, et al. Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells. Nat Commun. 2016;7:11272doi: 10.1038/ncomms11272.
Kato, Y., Katsuki, T., Kokubo, H., Masuda, A., & Saga, Y. (2016). Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells. Nature communications, 711272. https://doi.org/10.1038/ncomms11272
Kato, Yuzuru, et al. "Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells." Nature communications vol. 7 (2016): 11272. doi: https://doi.org/10.1038/ncomms11272
Kato Y, Katsuki T, Kokubo H, Masuda A, Saga Y. Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells. Nat Commun. 2016 Apr 13;7:11272. doi: 10.1038/ncomms11272. PMID: 27072294; PMCID: PMC4833867.
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Distinguishing between High- and Low-Spin States for Divalent Mn in Mn-Based Prussian Blue Analogue by High-Resolution Soft X-ray Emission Spectroscopy.

The journal of physical chemistry letters

Asakura D, Nanba Y, Okubo M, Mizuno Y, Niwa H, Oshima M, Zhou H, Okada K, Harada Y.
PMID: 26276486
J Phys Chem Lett. 2014 Nov 20;5(22):4008-13. doi: 10.1021/jz501738m. Epub 2014 Nov 05.

We combine Mn L2,3-edge X-ray absorption, high resolution Mn 2p-3d-2p resonant X-ray emission, and configuration-interaction full-multiplet (CIFM) calculation to analyze the electronic structure of Mn-based Prussian blue analogue. We clarified the Mn 3d energy diagram for the Mn(2+) low-spin...

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Asakura D, Nanba Y, Okubo M, et al. Distinguishing between High- and Low-Spin States for Divalent Mn in Mn-Based Prussian Blue Analogue by High-Resolution Soft X-ray Emission Spectroscopy. J Phys Chem Lett. 2014;5(22):4008-13doi: 10.1021/jz501738m.
Asakura, D., Nanba, Y., Okubo, M., Mizuno, Y., Niwa, H., Oshima, M., Zhou, H., Okada, K., & Harada, Y. (2014). Distinguishing between High- and Low-Spin States for Divalent Mn in Mn-Based Prussian Blue Analogue by High-Resolution Soft X-ray Emission Spectroscopy. The journal of physical chemistry letters, 5(22), 4008-13. https://doi.org/10.1021/jz501738m
Asakura, Daisuke, et al. "Distinguishing between High- and Low-Spin States for Divalent Mn in Mn-Based Prussian Blue Analogue by High-Resolution Soft X-ray Emission Spectroscopy." The journal of physical chemistry letters vol. 5,22 (2014): 4008-13. doi: https://doi.org/10.1021/jz501738m
Asakura D, Nanba Y, Okubo M, Mizuno Y, Niwa H, Oshima M, Zhou H, Okada K, Harada Y. Distinguishing between High- and Low-Spin States for Divalent Mn in Mn-Based Prussian Blue Analogue by High-Resolution Soft X-ray Emission Spectroscopy. J Phys Chem Lett. 2014 Nov 20;5(22):4008-13. doi: 10.1021/jz501738m. Epub 2014 Nov 05. PMID: 26276486.
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Squamous Cell Carcinoma of the Tongue Dorsum: Incidence and Treatment Considerations.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

Okubo M, Iwai T, Nakashima H, Koizumi T, Oguri S, Hirota M, Mitsudo K, Tohnai I.
PMID: 28239570
Indian J Otolaryngol Head Neck Surg. 2017 Mar;69(1):6-10. doi: 10.1007/s12070-016-0979-z. Epub 2016 May 07.

Squamous cell carcinoma (SCC) of the tongue is the most common oral cancer. Most cases occur on the lateral border of the tongue and only very rarely on the dorsum. We retrospectively investigated the incidence of SCC of the...

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Okubo M, Iwai T, Nakashima H, et al. Squamous Cell Carcinoma of the Tongue Dorsum: Incidence and Treatment Considerations. Indian J Otolaryngol Head Neck Surg. 2016;69(1):6-10doi: 10.1007/s12070-016-0979-z.
Okubo, M., Iwai, T., Nakashima, H., Koizumi, T., Oguri, S., Hirota, M., Mitsudo, K., & Tohnai, I. (2017). Squamous Cell Carcinoma of the Tongue Dorsum: Incidence and Treatment Considerations. Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 69(1), 6-10. https://doi.org/10.1007/s12070-016-0979-z
Okubo, Makiko, et al. "Squamous Cell Carcinoma of the Tongue Dorsum: Incidence and Treatment Considerations." Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India vol. 69,1 (2017): 6-10. doi: https://doi.org/10.1007/s12070-016-0979-z
Okubo M, Iwai T, Nakashima H, Koizumi T, Oguri S, Hirota M, Mitsudo K, Tohnai I. Squamous Cell Carcinoma of the Tongue Dorsum: Incidence and Treatment Considerations. Indian J Otolaryngol Head Neck Surg. 2017 Mar;69(1):6-10. doi: 10.1007/s12070-016-0979-z. Epub 2016 May 07. PMID: 28239570; PMCID: PMC5305651.
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Transcriptomic analyses of Hand2 transgenic embryos.

Genomics data

Funato N, Kokubo H, Saga Y.
PMID: 27408813
Genom Data. 2016 Jun 25;9:60-2. doi: 10.1016/j.gdata.2016.06.015. eCollection 2016 Sep.

In this article, we further provide the data generated for the previously published research article "Specification of jaw identity by the Hand2 transcription factor." To better understand the downstream genes of the basic helix-loop-helix transcription factor Hand2, we generated...

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Funato N, Kokubo H, Saga Y. Transcriptomic analyses of Hand2 transgenic embryos. Genom Data. 2016;9:60-2doi: 10.1016/j.gdata.2016.06.015.
Funato, N., Kokubo, H., & Saga, Y. (2016). Transcriptomic analyses of Hand2 transgenic embryos. Genomics data, 960-2. https://doi.org/10.1016/j.gdata.2016.06.015
Funato, Noriko, et al. "Transcriptomic analyses of Hand2 transgenic embryos." Genomics data vol. 9 (2016): 60-2. doi: https://doi.org/10.1016/j.gdata.2016.06.015
Funato N, Kokubo H, Saga Y. Transcriptomic analyses of Hand2 transgenic embryos. Genom Data. 2016 Jun 25;9:60-2. doi: 10.1016/j.gdata.2016.06.015. eCollection 2016 Sep. PMID: 27408813; PMCID: PMC4932614.
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Spatial and temporal expression pattern of Bombyx fork head/SGF-1 gene in embryogenesis.

Development genes and evolution

Kokubo H, Takiya S, Mach V, Suzuki Y.
PMID: 24173400
Dev Genes Evol. 1996 Jun;206(1):80-5. doi: 10.1007/s004270050033.

The embryonic expression of Bombyx fkh/SGF-1 gene has been analysed using in situ hybridization and immunohistochemistry. Both transcripts and protein were first detected in the most anterior and posterior regions at the time of germ anlage formation, and were...

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Kokubo H, Takiya S, Mach V, et al. Spatial and temporal expression pattern of Bombyx fork head/SGF-1 gene in embryogenesis. Dev Genes Evol. 1996;206(1):80-5doi: 10.1007/s004270050033.
Kokubo, H., Takiya, S., Mach, V., & Suzuki, Y. (1996). Spatial and temporal expression pattern of Bombyx fork head/SGF-1 gene in embryogenesis. Development genes and evolution, 206(1), 80-5. https://doi.org/10.1007/s004270050033
Kokubo, H, et al. "Spatial and temporal expression pattern of Bombyx fork head/SGF-1 gene in embryogenesis." Development genes and evolution vol. 206,1 (1996): 80-5. doi: https://doi.org/10.1007/s004270050033
Kokubo H, Takiya S, Mach V, Suzuki Y. Spatial and temporal expression pattern of Bombyx fork head/SGF-1 gene in embryogenesis. Dev Genes Evol. 1996 Jun;206(1):80-5. doi: 10.1007/s004270050033. PMID: 24173400.
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Dialysis and quality of dialysate in southeast asian developing countries.

Nephron extra

Naramura T, Hyodo T, Kokubo K, Matsubara H, Wakai H, Nakajima F, Shibahara N, Yoshida K, Komaru Y, Kawanishi H, Kawamura A, Hidai H, Takesawa S.
PMID: 24926310
Nephron Extra. 2014 Apr 23;4(1):64-9. doi: 10.1159/000362454. eCollection 2014 Jan.

BACKGROUND: The number of dialysis patients has been increasing in Southeast Asia, but statistical data about these patients and on the quality of dialysates in Southeast Asian dialysis facilities are still imprecise. For this study, dialysis-related statistical data were...

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Naramura T, Hyodo T, Kokubo K, et al. Dialysis and quality of dialysate in southeast asian developing countries. Nephron Extra. 2014;4(1):64-9doi: 10.1159/000362454.
Naramura, T., Hyodo, T., Kokubo, K., Matsubara, H., Wakai, H., Nakajima, F., Shibahara, N., Yoshida, K., Komaru, Y., Kawanishi, H., Kawamura, A., Hidai, H., & Takesawa, S. (2014). Dialysis and quality of dialysate in southeast asian developing countries. Nephron extra, 4(1), 64-9. https://doi.org/10.1159/000362454
Naramura, Tomotaka, et al. "Dialysis and quality of dialysate in southeast asian developing countries." Nephron extra vol. 4,1 (2014): 64-9. doi: https://doi.org/10.1159/000362454
Naramura T, Hyodo T, Kokubo K, Matsubara H, Wakai H, Nakajima F, Shibahara N, Yoshida K, Komaru Y, Kawanishi H, Kawamura A, Hidai H, Takesawa S. Dialysis and quality of dialysate in southeast asian developing countries. Nephron Extra. 2014 Apr 23;4(1):64-9. doi: 10.1159/000362454. eCollection 2014 Jan. PMID: 24926310; PMCID: PMC4036132.
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A case of plummer-vinson syndrome showing rapid improvement of Dysphagia and esophageal web after two weeks of iron therapy.

Case reports in gastroenterology

Tahara T, Shibata T, Okubo M, Yoshioka D, Ishizuka T, Sumi K, Kawamura T, Nagasaka M, Nakagawa Y, Nakamura M, Arisawa T, Ohmiya N, Hirata I.
PMID: 25028578
Case Rep Gastroenterol. 2014 Jun 07;8(2):211-5. doi: 10.1159/000364820. eCollection 2014 May.

Plummer-Vinson syndrome (PVS) is a rare entity characterized by upper esophageal webs and iron deficiency anemia. We report a case of PVS whose esophageal web was rapidly improved by iron therapy. A 77-year-old woman was admitted to our hospital...

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Tahara T, Shibata T, Okubo M, et al. A case of plummer-vinson syndrome showing rapid improvement of Dysphagia and esophageal web after two weeks of iron therapy. Case Rep Gastroenterol. 2014;8(2):211-5doi: 10.1159/000364820.
Tahara, T., Shibata, T., Okubo, M., Yoshioka, D., Ishizuka, T., Sumi, K., Kawamura, T., Nagasaka, M., Nakagawa, Y., Nakamura, M., Arisawa, T., Ohmiya, N., & Hirata, I. (2014). A case of plummer-vinson syndrome showing rapid improvement of Dysphagia and esophageal web after two weeks of iron therapy. Case reports in gastroenterology, 8(2), 211-5. https://doi.org/10.1159/000364820
Tahara, Tomomitsu, et al. "A case of plummer-vinson syndrome showing rapid improvement of Dysphagia and esophageal web after two weeks of iron therapy." Case reports in gastroenterology vol. 8,2 (2014): 211-5. doi: https://doi.org/10.1159/000364820
Tahara T, Shibata T, Okubo M, Yoshioka D, Ishizuka T, Sumi K, Kawamura T, Nagasaka M, Nakagawa Y, Nakamura M, Arisawa T, Ohmiya N, Hirata I. A case of plummer-vinson syndrome showing rapid improvement of Dysphagia and esophageal web after two weeks of iron therapy. Case Rep Gastroenterol. 2014 Jun 07;8(2):211-5. doi: 10.1159/000364820. eCollection 2014 May. PMID: 25028578; PMCID: PMC4086037.
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Nonlinear piezoelectricity in PZT ceramics for generating ultrasonic phase conjugate waves.

Ultrasonics

Yamamoto K, Kokubo A, Sakai K, Takagi K.
PMID: 10829782
Ultrasonics. 2000 Mar;38(1):830-3. doi: 10.1016/s0041-624x(99)00070-0.

We have succeeded in the generation of acoustic phase conjugate waves with nonlinear PZT piezoelectric ceramics and applied them to ultrasonic imaging systems. Our aim is to make a phase conjugator with 100% efficiency. For this purpose, it is...

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Yamamoto K, Kokubo A, Sakai K, et al. Nonlinear piezoelectricity in PZT ceramics for generating ultrasonic phase conjugate waves. Ultrasonics. 2000;38(1):830-3doi: 10.1016/s0041-624x(99)00070-0.
Yamamoto, K., Kokubo, A., Sakai, K., & Takagi, K. (2000). Nonlinear piezoelectricity in PZT ceramics for generating ultrasonic phase conjugate waves. Ultrasonics, 38(1), 830-3. https://doi.org/10.1016/s0041-624x(99)00070-0
Yamamoto, et al. "Nonlinear piezoelectricity in PZT ceramics for generating ultrasonic phase conjugate waves." Ultrasonics vol. 38,1 (2000): 830-3. doi: https://doi.org/10.1016/s0041-624x(99)00070-0
Yamamoto K, Kokubo A, Sakai K, Takagi K. Nonlinear piezoelectricity in PZT ceramics for generating ultrasonic phase conjugate waves. Ultrasonics. 2000 Mar;38(1):830-3. doi: 10.1016/s0041-624x(99)00070-0. PMID: 10829782.
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