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Showing 1 to 12 of 88 entries
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Behaviour in aggregates of irradiated imaginal disk cells ofDrosophila.

Wilhelm Roux' Archiv fur Entwicklungsmechanik der Organismen

Morata G, Garcia-Bellido A.
PMID: 28305244
Wilhelm Roux Arch Entwickl Mech Org. 1973 Sep;172(3):187-195. doi: 10.1007/BF00582074.

The ability of dissociated cells to reaggregate, grow in culture (in vivo) and differentiate cuticular structures following increasing doses of X-ray radiation has been studied.At low doses (up to 5 Kr) reaggregation, but not cell viability, is affected. The...

Draft Genome Sequences of Four Bacterial Strains Isolated from a Polymicrobial Culture of Naked (N-Type) Emiliania huxleyi CCMP1516.

Genome announcements

Orata FD, Rosana AR, Xu Y, Simkus DN, Bramucci AR, Boucher Y, Case RJ.
PMID: 27417846
Genome Announc. 2016 Jul 14;4(4). doi: 10.1128/genomeA.00674-16.

Strains of Sulfitobacter spp., Erythrobacter sp., and Marinobacter sp. were isolated from a polymicrobial culture of the naked (N-type) haptophyte Emiliania huxleyi strain CCMP1516. The genomes encode genes for the production of phytohormones, vitamins, and the consumption of their...

High density lipoproteins and atherosclerosis: emerging aspects.

Journal of geriatric cardiology : JGC

Sala F, Catapano AL, Norata GD.
PMID: 23341845
J Geriatr Cardiol. 2012 Dec;9(4):401-7. doi: 10.3724/SP.J.1263.2011.12282.

High density lipoproteins (HDL) promote the efflux of excess cholesterol from peripheral tissues to the liver for excretion. This ability is responsible for the most relevant anti-atherogenic effect of HDL. The ability of HDL to promote cholesterol efflux results...

Established and emerging approaches for the management of dyslipidaemia.

Scientifica

Norata GD.
PMID: 24278703
Scientifica (Cairo). 2012;2012:482423. doi: 10.6064/2012/482423. Epub 2012 Sep 10.

The key role of dyslipidaemia in determining cardiovascular disease (CVD) has been proved beyond reasonable doubt, and therefore several dietary and pharmacological approaches have been developed. The discovery of statins has provided a very effective approach in reducing cardiovascular...

Palaeopermeability anisotropy and geometrical properties of sealed-microfractures from micro-CT analyses: An open-source implementation.

Micron (Oxford, England : 1993)

Gomila R, Arancibia G, Mery D, Nehler M, Bracke R, Morata D.
PMID: 30458300
Micron. 2019 Feb;117:29-39. doi: 10.1016/j.micron.2018.11.001. Epub 2018 Nov 10.

Fault zone permeability and the real 3D-spatial distribution of the fault-related fracture networks are critical in the assessment of fault zones behavior for fluids. The study of the real 3D-spatial distribution of the microfracture network, using X-ray micro-computed tomography,...

Phylogenomic Analysis of the Gammaproteobacterial Methanotrophs (Order .

Frontiers in microbiology

Orata FD, Meier-Kolthoff JP, Sauvageau D, Stein LY.
PMID: 30631317
Front Microbiol. 2018 Dec 19;9:3162. doi: 10.3389/fmicb.2018.03162. eCollection 2018.

The order

Influence of Research Continuity on Physician-Scientists' Career Success.

Neurology

Brownrout J, Norato G, Bensken W, Squirewell C, Gordon T, Heiss J, Nath A, Khan OI.
PMID: 34670817
Neurology. 2021 Nov 16;97(20):e2039-e2045. doi: 10.1212/WNL.0000000000012867. Epub 2021 Oct 20.

OBJECTIVE: To determine if maintaining continuity in research topic and method from early to late career yields a greater likelihood of physician-scientists' research career success; that is, achieving research independence and producing impactful publications.METHODS: To explore the effect of...

A Randomized Controlled Trial of SGS-742, a γ-aminobutyric acid B (GABA-B) Receptor Antagonist, for Succinic Semialdehyde Dehydrogenase Deficiency.

Journal of child neurology

Schreiber JM, Wiggs E, Cuento R, Norato G, Dustin IH, Rolinski R, Austermuehle A, Zhou X, Inati SK, Gibson KM, Pearl PL, Theodore WH.
PMID: 34015244
J Child Neurol. 2021 Nov;36(13):1189-1199. doi: 10.1177/08830738211012804. Epub 2021 May 20.

We examined safety, tolerability, and efficacy of SGS-742, a γ-aminobutyric acid B (GABA-B) receptor antagonist, in patients with succinic semialdehyde dehydrogenase deficiency. This was a single-center randomized, double-blind crossover phase II clinical trial of SGS-742 versus placebo in patients...

Genetically determined hypercholesterolaemia results into premature leucocyte telomere length shortening and reduced haematopoietic precursors.

European journal of preventive cardiology

Baragetti A, Bonacina F, Da Dalt L, Moregola A, Zampoleri V, Pellegatta F, Grigore L, Pirillo A, Spina R, Cefalù AB, Averna M, Norata GD, Catapano AL.
PMID: 33624064
Eur J Prev Cardiol. 2020 Nov 17; doi: 10.1093/eurjpc/zwaa115. Epub 2020 Nov 17.

AIMS: Leucocyte telomere length (LTL) shortening is a marker of cellular senescence and associates with increased risk of cardiovascular disease (CVD). A number of cardiovascular risk factors affect LTL, but the correlation between elevated LDL cholesterol (LDL-C) and shorter...

Therapeutic Targeting of Acute Myeloid Leukemia by Gemtuzumab Ozogamicin.

Cancers

Gottardi M, Simonetti G, Sperotto A, Nappi D, Ghelli Luserna di Rorà A, Padella A, Norata M, Giannini MB, Musuraca G, Lanza F, Cerchione C, Martinelli G.
PMID: 34572794
Cancers (Basel). 2021 Sep 11;13(18). doi: 10.3390/cancers13184566.

Acute myeloid leukemia (AML) is a complex hematological malignancy characterized by genetic and clinical heterogeneity and high mortality. Despite the recent introduction of novel pharmaceutical agents in hemato-oncology, few advancements have been made in AML for decades. In the...

Impact of protein glycosylation on lipoprotein metabolism and atherosclerosis.

Cardiovascular research

Pirillo A, Svecla M, Catapano AL, Holleboom AG, Norata GD.
PMID: 32886765
Cardiovasc Res. 2021 Mar 21;117(4):1033-1045. doi: 10.1093/cvr/cvaa252.

Protein glycosylation is a post-translational modification consisting in the enzymatic attachment of carbohydrate chains to specific residues of the protein sequence. Several types of glycosylation have been described, with N-glycosylation and O-glycosylation being the most common types impacting on...

Chromatin remodelling and retrotransposons activities during regeneration in Drosophila.

Developmental biology

Azpiazu N, Morata G.
PMID: 34822846
Dev Biol. 2021 Nov 22;482:7-16. doi: 10.1016/j.ydbio.2021.11.005. Epub 2021 Nov 22.

Regeneration is a response mechanism aiming to reconstruct lost or damaged structures. To achieve this, the cells repopulating the lost tissue often have to change their original identity, a process that involves chromatin remodelling.We have analysed the issue of...

Showing 1 to 12 of 88 entries