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T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours.

Nature biomedical engineering

Lesch S, Blumenberg V, Stoiber S, Gottschlich A, Ogonek J, Cadilha BL, Dantes Z, Rataj F, Dorman K, Lutz J, Karches CH, Heise C, Kurzay M, Larimer BM, Grassmann S, Rapp M, Nottebrock A, Kruger S, Tokarew N, Metzger P, Hoerth C, Benmebarek MR, Dhoqina D, Grünmeier R, Seifert M, Oener A, Umut Ö, Joaquina S, Vimeux L, Tran T, Hank T, Baba T, Huynh D, Megens RTA, Janssen KP, Jastroch M, Lamp D, Ruehland S, Di Pilato M, Pruessmann JN, Thomas M, Marr C, Ormanns S, Reischer A, Hristov M, Tartour E, Donnadieu E, Rothenfusser S, Duewell P, König LM, Schnurr M, Subklewe M, Liss AS, Halama N, Reichert M, Mempel TR, Endres S, Kobold S.
PMID: 34083764
Nat Biomed Eng. 2021 Nov;5(11):1246-1260. doi: 10.1038/s41551-021-00737-6. Epub 2021 Jun 03.

The efficacy of adoptive cell therapy for solid tumours is hampered by the poor accumulation of the transferred T cells in tumour tissue. Here, we show that forced expression of C-X-C chemokine receptor type 6 (whose ligand is highly...

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Lesch S, Blumenberg V, Stoiber S, et al. T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours. Nat Biomed Eng. 2021;5(11):1246-1260doi: 10.1038/s41551-021-00737-6.
Lesch, S., Blumenberg, V., Stoiber, S., Gottschlich, A., Ogonek, J., Cadilha, B. L., Dantes, Z., Rataj, F., Dorman, K., Lutz, J., Karches, C. H., Heise, C., Kurzay, M., Larimer, B. M., Grassmann, S., Rapp, M., Nottebrock, A., Kruger, S., Tokarew, N., Metzger, P., Hoerth, C., Benmebarek, M. R., Dhoqina, D., Grünmeier, R., Seifert, M., Oener, A., Umut, �. �., Joaquina, S., Vimeux, L., Tran, T., Hank, T., Baba, T., Huynh, D., Megens, R. T. A., Janssen, K. P., Jastroch, M., Lamp, D., Ruehland, S., Di Pilato, M., Pruessmann, J. N., Thomas, M., Marr, C., Ormanns, S., Reischer, A., Hristov, M., Tartour, E., Donnadieu, E., Rothenfusser, S., Duewell, P., König, L. M., Schnurr, M., Subklewe, M., Liss, A. S., Halama, N., Reichert, M., Mempel, T. R., Endres, S., & Kobold, S. (2021). T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours. Nature biomedical engineering, 5(11), 1246-1260. https://doi.org/10.1038/s41551-021-00737-6
Lesch, Stefanie, et al. "T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours." Nature biomedical engineering vol. 5,11 (2021): 1246-1260. doi: https://doi.org/10.1038/s41551-021-00737-6
Lesch S, Blumenberg V, Stoiber S, Gottschlich A, Ogonek J, Cadilha BL, Dantes Z, Rataj F, Dorman K, Lutz J, Karches CH, Heise C, Kurzay M, Larimer BM, Grassmann S, Rapp M, Nottebrock A, Kruger S, Tokarew N, Metzger P, Hoerth C, Benmebarek MR, Dhoqina D, Grünmeier R, Seifert M, Oener A, Umut Ö, Joaquina S, Vimeux L, Tran T, Hank T, Baba T, Huynh D, Megens RTA, Janssen KP, Jastroch M, Lamp D, Ruehland S, Di Pilato M, Pruessmann JN, Thomas M, Marr C, Ormanns S, Reischer A, Hristov M, Tartour E, Donnadieu E, Rothenfusser S, Duewell P, König LM, Schnurr M, Subklewe M, Liss AS, Halama N, Reichert M, Mempel TR, Endres S, Kobold S. T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours. Nat Biomed Eng. 2021 Nov;5(11):1246-1260. doi: 10.1038/s41551-021-00737-6. Epub 2021 Jun 03. PMID: 34083764; PMCID: PMC7611996.
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Predictive ability of a process-based versus a correlative species distribution model.

Ecology and evolution

Higgins SI, Larcombe MJ, Beeton NJ, Conradi T, Nottebrock H.
PMID: 33144947
Ecol Evol. 2020 Oct 08;10(20):11043-11054. doi: 10.1002/ece3.6712. eCollection 2020 Oct.

Species distribution modeling is a widely used tool in many branches of ecology and evolution. Evaluations of the transferability of species distribution models-their ability to predict the distribution of species in independent data domains-are, however, rare. In this study,...

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Higgins SI, Larcombe MJ, Beeton NJ, et al. Predictive ability of a process-based versus a correlative species distribution model. Ecol Evol. 2020;10(20):11043-11054doi: 10.1002/ece3.6712.
Higgins, S. I., Larcombe, M. J., Beeton, N. J., Conradi, T., & Nottebrock, H. (2020). Predictive ability of a process-based versus a correlative species distribution model. Ecology and evolution, 10(20), 11043-11054. https://doi.org/10.1002/ece3.6712
Higgins, Steven I, et al. "Predictive ability of a process-based versus a correlative species distribution model." Ecology and evolution vol. 10,20 (2020): 11043-11054. doi: https://doi.org/10.1002/ece3.6712
Higgins SI, Larcombe MJ, Beeton NJ, Conradi T, Nottebrock H. Predictive ability of a process-based versus a correlative species distribution model. Ecol Evol. 2020 Oct 08;10(20):11043-11054. doi: 10.1002/ece3.6712. eCollection 2020 Oct. PMID: 33144947; PMCID: PMC7593166.
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Preoperative medication use and development of postoperative delirium and cognitive dysfunction.

Clinical and translational science

Heinrich M, Nottbrock A, Borchers F, Mörgeli R, Kruppa J, Winterer G, Slooter AJC, Spies C.
PMID: 33934508
Clin Transl Sci. 2021 Sep;14(5):1830-1840. doi: 10.1111/cts.13031. Epub 2021 May 02.

Postoperative delirium (POD) and postoperative (neuro-)cognitive disorder (POCD) are frequent and serious complications after operations. We aim to investigate the association between pre-operative polypharmacy and potentially inappropriate medications and the development of POD/POCD in elderly patients. This investigation is...

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Heinrich M, Nottbrock A, Borchers F, et al. Preoperative medication use and development of postoperative delirium and cognitive dysfunction. Clin Transl Sci. 2021;14(5):1830-1840doi: 10.1111/cts.13031.
Heinrich, M., Nottbrock, A., Borchers, F., Mörgeli, R., Kruppa, J., Winterer, G., Slooter, A. J. C., Spies, C. (2021). Preoperative medication use and development of postoperative delirium and cognitive dysfunction. Clinical and translational science, 14(5), 1830-1840. https://doi.org/10.1111/cts.13031
Heinrich, Maria, et al. "Preoperative medication use and development of postoperative delirium and cognitive dysfunction." Clinical and translational science vol. 14,5 (2021): 1830-1840. doi: https://doi.org/10.1111/cts.13031
Heinrich M, Nottbrock A, Borchers F, Mörgeli R, Kruppa J, Winterer G, Slooter AJC, Spies C. Preoperative medication use and development of postoperative delirium and cognitive dysfunction. Clin Transl Sci. 2021 Sep;14(5):1830-1840. doi: 10.1111/cts.13031. Epub 2021 May 02. PMID: 33934508; PMCID: PMC8504833.
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Showing 1 to 3 of 3 entries