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Chiral amine synthesis–recent developments and trends for enamide reduction, reductive amination, and imine reduction

science campus

Nugent TC, El‐Shazly M.
GSID: bhsgcF8sjGgJ
TC Nugent, M El‐Shazly - Advanced Synthesis & Catalysis, 2010 - Wiley Online Library

The review examines the chiral amine literature from 2000–2009 (May) concerning enantioselective and diastereoselective methods for N‐acylenamide and enamine reduction, reductive amination, and imine reduction. The reaction steps for each strategy, from ketone to …

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Nugent, T. C., & El‐Shazly, M. (2010). Chiral amine synthesis–recent developments and trends for enamide reduction, reductive amination, and imine reduction. Advanced Synthesis & Catalysis, 352(5), 753-819.
Nugent, Thomas C., and Mohamed El‐Shazly. "Chiral amine synthesis–recent developments and trends for enamide reduction, reductive amination, and imine reduction." Advanced Synthesis & Catalysis 352.5 (2010): 753-819.
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Roads, rails and race cars

STEM training programs

Nugent GC, Rilett LR.
GSID: OzGoSs8V-AEJ
CM Baker, LR Rilett, GM Kunz, GC Nugent - American Society for Engineering …, 2014

No abstract available.

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Baker, C. M., Rilett, L. R., Kunz, G. M., & Nugent, G. C. (2014). Roads, rails and race cars. In American Society for Engineering Education.
Baker, Cynthia Marie, et al. "Roads, rails and race cars." American Society for Engineering Education. 2014.
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Indoor localisation through object detection within multiple environments utilising a single wearable camera.

Health and technology

Shewell C, Nugent C, Donnelly M, Wang H, Espinilla M.
PMID: 28344913
Health Technol (Berl). 2017;7(1):51-60. doi: 10.1007/s12553-016-0159-x. Epub 2016 Dec 22.

The recent growth in the wearable sensor market has stimulated new opportunities within the domain of Ambient Assisted Living, providing unique methods of collecting occupant information. This approach leverages contemporary wearable technology, Google Glass, to facilitate a unique first-person...

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Shewell C, Nugent C, Donnelly M, et al. Indoor localisation through object detection within multiple environments utilising a single wearable camera. Health Technol (Berl). 2016;7(1):51-60doi: 10.1007/s12553-016-0159-x.
Shewell, C., Nugent, C., Donnelly, M., Wang, H., & Espinilla, M. (2017). Indoor localisation through object detection within multiple environments utilising a single wearable camera. Health and technology, 7(1), 51-60. https://doi.org/10.1007/s12553-016-0159-x
Shewell, Colin, et al. "Indoor localisation through object detection within multiple environments utilising a single wearable camera." Health and technology vol. 7,1 (2017): 51-60. doi: https://doi.org/10.1007/s12553-016-0159-x
Shewell C, Nugent C, Donnelly M, Wang H, Espinilla M. Indoor localisation through object detection within multiple environments utilising a single wearable camera. Health Technol (Berl). 2017;7(1):51-60. doi: 10.1007/s12553-016-0159-x. Epub 2016 Dec 22. PMID: 28344913; PMCID: PMC5346438.
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Rich context information for just-in-time adaptive intervention promoting physical activity.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Cruciani F, Nugent C, Cleland I, McCullagh P.
PMID: 29060005
Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul;2017:849-852. doi: 10.1109/EMBC.2017.8036957.

Sedentary lifestyle and inadequate levels of physical activity represent two serious health risk factors. Nevertheless, within developed countries, 60% of people aged over 60 are deemed to be sedentary. Consequently, interest in behavior change to promote physical activity is...

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Cruciani F, Nugent C, Cleland I, et al. Rich context information for just-in-time adaptive intervention promoting physical activity. Annu Int Conf IEEE Eng Med Biol Soc. 2017;2017:849-852doi: 10.1109/EMBC.2017.8036957.
Cruciani, F., Nugent, C., Cleland, I., & McCullagh, P. (2017). Rich context information for just-in-time adaptive intervention promoting physical activity. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2017849-852. https://doi.org/10.1109/EMBC.2017.8036957
Cruciani, F, et al. "Rich context information for just-in-time adaptive intervention promoting physical activity." Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference vol. 2017 (2017): 849-852. doi: https://doi.org/10.1109/EMBC.2017.8036957
Cruciani F, Nugent C, Cleland I, McCullagh P. Rich context information for just-in-time adaptive intervention promoting physical activity. Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul;2017:849-852. doi: 10.1109/EMBC.2017.8036957. PMID: 29060005.
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Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review.

Therapeutic advances in chronic disease

Iadarola ND, Niciu MJ, Richards EM, Vande Voort JL, Ballard ED, Lundin NB, Nugent AC, Machado-Vieira R, Zarate CA.
PMID: 25954495
Ther Adv Chronic Dis. 2015 May;6(3):97-114. doi: 10.1177/2040622315579059.

Current pharmacotherapies for major depressive disorder (MDD) and bipolar depression (BDep) have a distinct lag of onset that can generate great distress and impairment in patients. Furthermore, as demonstrated by several real-world effectiveness trials, their efficacy is limited. All...

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Iadarola ND, Niciu MJ, Richards EM, et al. Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review. Ther Adv Chronic Dis. 2015;6(3):97-114doi: 10.1177/2040622315579059.
Iadarola, N. D., Niciu, M. J., Richards, E. M., Vande Voort, J. L., Ballard, E. D., Lundin, N. B., Nugent, A. C., Machado-Vieira, R., & Zarate, C. A. (2015). Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review. Therapeutic advances in chronic disease, 6(3), 97-114. https://doi.org/10.1177/2040622315579059
Iadarola, Nicolas D, et al. "Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review." Therapeutic advances in chronic disease vol. 6,3 (2015): 97-114. doi: https://doi.org/10.1177/2040622315579059
Iadarola ND, Niciu MJ, Richards EM, Vande Voort JL, Ballard ED, Lundin NB, Nugent AC, Machado-Vieira R, Zarate CA. Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review. Ther Adv Chronic Dis. 2015 May;6(3):97-114. doi: 10.1177/2040622315579059. PMID: 25954495; PMCID: PMC4416968.
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Technology adoption and prediction tools for everyday technologies aimed at people with dementia.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Chaurasia P, McClean SI, Nugent CD, Cleland I, Shuai Zhang, Donnelly MP, Scotney BW, Sanders C, Smith K, Norton MC, Tschanz J.
PMID: 28269255
Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug;2016:4407-4410. doi: 10.1109/EMBC.2016.7591704.

A wide range of assistive technologies have been developed to support the elderly population with the goal of promoting independent living. The adoption of these technology based solutions is, however, critical to their overarching success. In our previous research...

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Chaurasia P, McClean SI, Nugent CD, et al. Technology adoption and prediction tools for everyday technologies aimed at people with dementia. Annu Int Conf IEEE Eng Med Biol Soc. 2016;2016:4407-4410doi: 10.1109/EMBC.2016.7591704.
Chaurasia, P., McClean, S. I., Nugent, C. D., Cleland, I., Shuai Zhang, Donnelly, M. P., Scotney, B. W., Sanders, C., Smith, K., Norton, M. C., & Tschanz, J. (2016). Technology adoption and prediction tools for everyday technologies aimed at people with dementia. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 20164407-4410. https://doi.org/10.1109/EMBC.2016.7591704
Chaurasia, Priyanka, et al. "Technology adoption and prediction tools for everyday technologies aimed at people with dementia." Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference vol. 2016 (2016): 4407-4410. doi: https://doi.org/10.1109/EMBC.2016.7591704
Chaurasia P, McClean SI, Nugent CD, Cleland I, Shuai Zhang, Donnelly MP, Scotney BW, Sanders C, Smith K, Norton MC, Tschanz J. Technology adoption and prediction tools for everyday technologies aimed at people with dementia. Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug;2016:4407-4410. doi: 10.1109/EMBC.2016.7591704. PMID: 28269255.
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Metabolic profiling of human peripheral blood mononuclear cells: influence of vitamin d status and gender.

Metabolites

Stepien M, Nugent AP, Brennan L.
PMID: 24957025
Metabolites. 2014 Apr 22;4(2):248-59. doi: 10.3390/metabo4020248.

Metabolic profiling of peripheral blood mononuclear cells (PBMC) could serve as a less invasive and more direct alternative to tissue biopsies or serum in metabolomic research. We conducted two exploratory independent studies in order to characterise PBMC's metabolomic profile...

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Stepien M, Nugent AP, Brennan L. Metabolic profiling of human peripheral blood mononuclear cells: influence of vitamin d status and gender. Metabolites. 2014;4(2):248-59doi: 10.3390/metabo4020248.
Stepien, M., Nugent, A. P., & Brennan, L. (2014). Metabolic profiling of human peripheral blood mononuclear cells: influence of vitamin d status and gender. Metabolites, 4(2), 248-59. https://doi.org/10.3390/metabo4020248
Stepien, Magdalena, et al. "Metabolic profiling of human peripheral blood mononuclear cells: influence of vitamin d status and gender." Metabolites vol. 4,2 (2014): 248-59. doi: https://doi.org/10.3390/metabo4020248
Stepien M, Nugent AP, Brennan L. Metabolic profiling of human peripheral blood mononuclear cells: influence of vitamin d status and gender. Metabolites. 2014 Apr 22;4(2):248-59. doi: 10.3390/metabo4020248. PMID: 24957025; PMCID: PMC4101505.
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Method for combinatorial screening of moisture vapor transmission rate.

Journal of combinatorial chemistry

Grunlan JC, Mehrabi AR, Chavira AT, Nugent AB, Saunders DL.
PMID: 12857103
J Comb Chem. 2003 Jul-Aug;5(4):362-8. doi: 10.1021/cc020112h.

A high-throughput method for screening the moisture vapor transmission rate of barrier films was developed. This moisture high-throughput screening (MHTS) technique is based upon a Nafion-crystal violet (CVN) sensor that changes color from yellow to green upon absorption of...

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Grunlan JC, Mehrabi AR, Chavira AT, et al. Method for combinatorial screening of moisture vapor transmission rate. J Comb Chem. 2003;5(4):362-8doi: 10.1021/cc020112h.
Grunlan, J. C., Mehrabi, A. R., Chavira, A. T., Nugent, A. B., & Saunders, D. L. (2003). Method for combinatorial screening of moisture vapor transmission rate. Journal of combinatorial chemistry, 5(4), 362-8. https://doi.org/10.1021/cc020112h
Grunlan, Jaime C, et al. "Method for combinatorial screening of moisture vapor transmission rate." Journal of combinatorial chemistry vol. 5,4 (2003): 362-8. doi: https://doi.org/10.1021/cc020112h
Grunlan JC, Mehrabi AR, Chavira AT, Nugent AB, Saunders DL. Method for combinatorial screening of moisture vapor transmission rate. J Comb Chem. 2003 Jul-Aug;5(4):362-8. doi: 10.1021/cc020112h. PMID: 12857103.
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Chiral proton catalysis: a catalytic enantioselective direct aza-Henry reaction.

Journal of the American Chemical Society

Nugent BM, Yoder RA, Johnston JN.
PMID: 15025457
J Am Chem Soc. 2004 Mar 24;126(11):3418-9. doi: 10.1021/ja031906i.

Despite Nature's longstanding ability to use a proton, the most prevalent Lewis acid, to both activate and orient a substrate during an enantioselective reaction, this work represents the first example of this phenomenon outside of a protein. A chiral,...

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Nugent BM, Yoder RA, Johnston JN. Chiral proton catalysis: a catalytic enantioselective direct aza-Henry reaction. J Am Chem Soc. 2004;126(11):3418-9doi: 10.1021/ja031906i.
Nugent, B. M., Yoder, R. A., & Johnston, J. N. (2004). Chiral proton catalysis: a catalytic enantioselective direct aza-Henry reaction. Journal of the American Chemical Society, 126(11), 3418-9. https://doi.org/10.1021/ja031906i
Nugent, Benjamin M, et al. "Chiral proton catalysis: a catalytic enantioselective direct aza-Henry reaction." Journal of the American Chemical Society vol. 126,11 (2004): 3418-9. doi: https://doi.org/10.1021/ja031906i
Nugent BM, Yoder RA, Johnston JN. Chiral proton catalysis: a catalytic enantioselective direct aza-Henry reaction. J Am Chem Soc. 2004 Mar 24;126(11):3418-9. doi: 10.1021/ja031906i. PMID: 15025457.
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Catecholamine depletion in first-degree relatives of individuals with mood disorders: An [(18)F]fluorodeoxyglucose positron emission tomography study.

NeuroImage. Clinical

Savitz J, Nugent AC, Bellgowan PS, Wright N, Tinsley R, Zarate CA, Herscovitch P, Drevets WC.
PMID: 24179788
Neuroimage Clin. 2013 Mar 05;2:341-55. doi: 10.1016/j.nicl.2013.02.004. eCollection 2013.

Catecholamine depletion with alpha-methylparatyrosine (AMPT) has previously been shown to induce depressive symptoms in currently remitted patients with major depressive disorder (MDD) but not healthy controls. Thus sensitivity to catecholamine depletion has been hypothesized to be an endophenotype of...

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Savitz J, Nugent AC, Bellgowan PS, et al. Catecholamine depletion in first-degree relatives of individuals with mood disorders: An [(18)F]fluorodeoxyglucose positron emission tomography study. Neuroimage Clin. 2013;2:341-55doi: 10.1016/j.nicl.2013.02.004.
Savitz, J., Nugent, A. C., Bellgowan, P. S., Wright, N., Tinsley, R., Zarate, C. A., Herscovitch, P., & Drevets, W. C. (2013). Catecholamine depletion in first-degree relatives of individuals with mood disorders: An [(18)F]fluorodeoxyglucose positron emission tomography study. NeuroImage. Clinical, 2341-55. https://doi.org/10.1016/j.nicl.2013.02.004
Savitz, Jonathan, et al. "Catecholamine depletion in first-degree relatives of individuals with mood disorders: An [(18)F]fluorodeoxyglucose positron emission tomography study." NeuroImage. Clinical vol. 2 (2013): 341-55. doi: https://doi.org/10.1016/j.nicl.2013.02.004
Savitz J, Nugent AC, Bellgowan PS, Wright N, Tinsley R, Zarate CA, Herscovitch P, Drevets WC. Catecholamine depletion in first-degree relatives of individuals with mood disorders: An [(18)F]fluorodeoxyglucose positron emission tomography study. Neuroimage Clin. 2013 Mar 05;2:341-55. doi: 10.1016/j.nicl.2013.02.004. eCollection 2013. PMID: 24179788; PMCID: PMC3778263.
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Prevalence of Delayed Nausea and/or Vomiting in Patients Treated With Oxaliplatin-Based Regimens for Colorectal Cancer.

Journal of oncology practice

Fleishman SB, Mahajan D, Rosenwald V, Nugent AV, Mirzoyev T.
PMID: 22942805
J Oncol Pract. 2012 May;8(3):136-40. doi: 10.1200/JOP.2010.000151. Epub 2011 Dec 20.

PURPOSE: To measure the prevalence of nausea and vomiting 2 to 5 days after oxaliplatin-based chemotherapy.PATIENTS AND METHODS: Sixty-four patients (55% men; 44% women) enrolled onto this cross-sectional study. Fifty-three (83%) had colon cancer and received oxaliplatin biweekly. Eleven...

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Fleishman SB, Mahajan D, Rosenwald V, et al. Prevalence of Delayed Nausea and/or Vomiting in Patients Treated With Oxaliplatin-Based Regimens for Colorectal Cancer. J Oncol Pract. 2011;8(3):136-40doi: 10.1200/JOP.2010.000151.
Fleishman, S. B., Mahajan, D., Rosenwald, V., Nugent, A. V., & Mirzoyev, T. (2012). Prevalence of Delayed Nausea and/or Vomiting in Patients Treated With Oxaliplatin-Based Regimens for Colorectal Cancer. Journal of oncology practice, 8(3), 136-40. https://doi.org/10.1200/JOP.2010.000151
Fleishman, Stewart B, et al. "Prevalence of Delayed Nausea and/or Vomiting in Patients Treated With Oxaliplatin-Based Regimens for Colorectal Cancer." Journal of oncology practice vol. 8,3 (2012): 136-40. doi: https://doi.org/10.1200/JOP.2010.000151
Fleishman SB, Mahajan D, Rosenwald V, Nugent AV, Mirzoyev T. Prevalence of Delayed Nausea and/or Vomiting in Patients Treated With Oxaliplatin-Based Regimens for Colorectal Cancer. J Oncol Pract. 2012 May;8(3):136-40. doi: 10.1200/JOP.2010.000151. Epub 2011 Dec 20. PMID: 22942805; PMCID: PMC3396799.
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The .

Proceedings (Baylor University. Medical Center)

Nugent C, Berdine G, Nugent K.
PMID: 29706835
Proc (Bayl Univ Med Cent). 2018 Apr 11;31(2):244-249. doi: 10.1080/08998280.2018.1441216. eCollection 2018 Apr.

The

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Nugent C, Berdine G, Nugent K. The . Proc (Bayl Univ Med Cent). 2018;31(2):244-249doi: 10.1080/08998280.2018.1441216.
Nugent, C., Berdine, G., & Nugent, K. (2018). The . Proceedings (Baylor University. Medical Center), 31(2), 244-249. https://doi.org/10.1080/08998280.2018.1441216
Nugent, Connie, et al. "The ." Proceedings (Baylor University. Medical Center) vol. 31,2 (2018): 244-249. doi: https://doi.org/10.1080/08998280.2018.1441216
Nugent C, Berdine G, Nugent K. The . Proc (Bayl Univ Med Cent). 2018 Apr 11;31(2):244-249. doi: 10.1080/08998280.2018.1441216. eCollection 2018 Apr. PMID: 29706835; PMCID: PMC5914483.
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Showing 1 to 12 of 223 entries