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Showing 1 to 12 of 16 entries
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Antimicrobial activity of four essential oils against pigmenting .

Italian journal of food safety

Pedonese F, Fratini F, Pistelli L, Porta FM, Ciccio PD, Fischetti R, Turchi B, Nuvoloni R.
PMID: 29564238
Ital J Food Saf. 2017 Dec 11;6(4):6939. doi: 10.4081/ijfs.2017.6939. eCollection 2017 Oct 20.

Essential oils (EOs) are mixtures of secondary metabolites of plant origin with many useful properties, among which the antimicrobial activity is also of interest for the food industry. EOs can exert their antimicrobial potential both directly, in food products...

Tumor cells in light-chain amyloidosis and myeloma show distinct transcriptional rewiring of normal plasma cell development.

Blood

Alameda D, Goicoechea I, Vicari M, Arriazu E, Nevone A, Rodriguez S, Lasa M, Puig N, Cedena MT, Alignani D, Garate S, Lara-Astiaso D, Vilas-Zornoza A, Sarvide S, Ocio EM, Lecumberri R, Garcia de Coca A, Labrador J, Gonzalez ME, Palomera L, Gironella M, Cabañas V, Casanova M, Oriol A, Krsnik I, Perez-Montaña A, de la Rubia J, de la Puerta JE, de Arriba F, Fazio VM, Martinez-Lopez J, Lahuerta JJ, Mateos MV, Odero MD, Prosper F, Weiner A, Amit I, Nuvolone M, San Miguel JF, Paiva B.
PMID: 34133718
Blood. 2021 Oct 28;138(17):1583-1589. doi: 10.1182/blood.2020009754.

Although light-chain amyloidosis (AL) and multiple myeloma (MM) are characterized by tumor plasma cell (PC) expansion in bone marrow (BM), their clinical presentation differs. Previous attempts to identify unique pathogenic mechanisms behind such differences were unsuccessful, and no studies...

Factors Predicting the Intention of Eating an Insect-Based Product.

Foods (Basel, Switzerland)

Mancini S, Sogari G, Menozzi D, Nuvoloni R, Torracca B, Moruzzo R, Paci G.
PMID: 31331106
Foods. 2019 Jul 19;8(7). doi: 10.3390/foods8070270.

This study provides a framework of the factors predicting the intention of eating an insect-based product. As part of the study, a seminar was carried out to explore how the provision of information about ecological, health, and gastronomic aspects...

Prospective urinary albumin/creatinine ratio for diagnosis, staging, and organ response assessment in renal AL amyloidosis: results from a large cohort of patients.

Clinical chemistry and laboratory medicine

Basset M, Milani P, Ferretti VV, Nuvolone M, Foli A, Benigna F, Nanci M, Bozzola M, Ripepi J, Sesta M, Russo F, Bosoni T, Klersy C, Albertini R, Merlini G, Palladini G.
PMID: 35018751
Clin Chem Lab Med. 2022 Jan 13; doi: 10.1515/cclm-2021-0912. Epub 2022 Jan 13.

OBJECTIVES: Quantification of 24 h-proteinuria is the gold standard for diagnosing, staging, and monitoring of patients with renal AL amyloidosis. However, 24 h-urine collection is cumbersome and may result in preanalytical error. In this prospective study, we investigated the...

Effects of Garlic Powder and Salt on Meat Quality and Microbial Loads of Rabbit Burgers.

Foods (Basel, Switzerland)

Mancini S, Mattioli S, Nuvoloni R, Pedonese F, Dal Bosco A, Paci G.
PMID: 32751777
Foods. 2020 Jul 31;9(8). doi: 10.3390/foods9081022.

The aim of the research study was to evaluate the effects of a common culinary spice such as garlic powder and salt addition on the quality and microbial shelf life of rabbit meat burgers. Rabbit burgers were evaluated for...

Effect of an Italian propolis on the growth of .

Italian journal of food safety

Pedonese F, Verani G, Torracca B, Turchi B, Felicioli A, Nuvoloni R.
PMID: 31897395
Ital J Food Saf. 2019 Dec 05;8(4):8036. doi: 10.4081/ijfs.2019.8036. eCollection 2019 Dec 05.

Propolis antimicrobial activity has been limitedly studied in food, particularly in dairy products. We studied the antimicrobial activity of an alcoholic extract of an Italian propolis in sterile skim milk, pasteurized cow's milk, and cow's and goat's whey cheese...

Pathotypes and Antimicrobial Susceptibility of .

Animals : an open access journal from MDPI

Bertelloni F, Cilia G, Bogi S, Ebani VV, Turini L, Nuvoloni R, Cerri D, Fratini F, Turchi B.
PMID: 32344604
Animals (Basel). 2020 Apr 24;10(4). doi: 10.3390/ani10040744.

Wild boar are among the most widespread wild mammals in Europe. Although this species can act as a reservoir for different pathogens, data about its role as a carrier of pathogenic and antimicrobial-resistant

Bone Marrow Microenvironment in Light-Chain Amyloidosis: In Vitro Expansion and Characterization of Mesenchymal Stromal Cells.

Biomedicines

Valsecchi C, Croce S, Maltese A, Montagna L, Lenta E, Nevone A, Girelli M, Milani P, Bosoni T, Massa M, Abbà C, Campanelli R, Ripepi J, De Silvestri A, Carolei A, Palladini G, Zecca M, Nuvolone M, Avanzini MA.
PMID: 34829752
Biomedicines. 2021 Oct 22;9(11). doi: 10.3390/biomedicines9111523.

Immunoglobulin light-chain amyloidosis (AL) is caused by misfolded light chains produced by a small B cell clone. Mesenchymal stromal cells (MSCs) have been reported to affect plasma cell behavior. We aimed to characterize bone marrow (BM)-MSCs from AL patients,...

A nationwide prospective registry of bortezomib-based therapy in light chain (AL) amyloidosis.

Leukemia & lymphoma

Palladini G, Celant S, Milani P, Summa V, Affronti G, Olimpieri PP, Petraglia S, Foli A, Nuvolone M, Merlini G, Russo P.
PMID: 34448427
Leuk Lymphoma. 2022 Jan;63(1):205-211. doi: 10.1080/10428194.2021.1971215. Epub 2021 Aug 27.

Until recently, no drug was labeled for AL amyloidosis. In 2011, the Italian Medicines Agency started a program to grant access to upfront bortezomib to patients with AL amyloidosis. All subjects were enrolled in a prospective online registry. Response...

Treating Protein Misfolding Diseases: Therapeutic Successes Against Systemic Amyloidoses.

Frontiers in pharmacology

Nevone A, Merlini G, Nuvolone M.
PMID: 32754033
Front Pharmacol. 2020 Jul 10;11:1024. doi: 10.3389/fphar.2020.01024. eCollection 2020.

Misfolding and extracellular deposition of proteins is the hallmark of a heterogeneous group of conditions collectively termed protein misfolding and deposition diseases or amyloidoses. These include both localized (e.g. Alzheimer's disease, prion diseases, type 2 diabetes mellitus) and systemic...

Correction: Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry.

PloS one

Marotta F, Garofolo G, Di Marcantonio L, Di Serafino G, Neri D, Romantini R, Sacchini L, Alessiani A, Di Donato G, Nuvoloni R, Janowicz A, Di Giannatale E.
PMID: 31697786
PLoS One. 2019 Nov 07;14(11):e0225231. doi: 10.1371/journal.pone.0225231. eCollection 2019.

[This corrects the article DOI: 10.1371/journal.pone.0223804.].

Protease-sensitive regions in amyloid light chains: what a common pattern of fragmentation across organs suggests about aggregation.

The FEBS journal

Mazzini G, Ricagno S, Caminito S, Rognoni P, Milani P, Nuvolone M, Basset M, Foli A, Russo R, Merlini G, Palladini G, Lavatelli F.
PMID: 34482629
FEBS J. 2021 Sep 05; doi: 10.1111/febs.16182. Epub 2021 Sep 05.

Light-chain (AL) amyloidosis is characterized by deposition of immunoglobulin light chains (LC) as fibrils in target organs. Alongside the full-length protein, abundant LC fragments are always present in AL deposits. Herein, by combining gel-based and mass spectrometry analyses, we...

Showing 1 to 12 of 16 entries