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Showing 1 to 7 of 7 entries
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Multicenter reliability of semiautomatic retinal layer segmentation using OCT.

Neurology(R) neuroimmunology & neuroinflammation

Oberwahrenbrock T, Traber GL, Lukas S, Gabilondo I, Nolan R, Songster C, Balk L, Petzold A, Paul F, Villoslada P, Brandt AU, Green AJ, Schippling S.
PMID: 29552598
Neurol Neuroimmunol Neuroinflamm. 2018 Mar 13;5(3):e449. doi: 10.1212/NXI.0000000000000449. eCollection 2018 May.

OBJECTIVE: To evaluate the inter-rater reliability of semiautomated segmentation of spectral domain optical coherence tomography (OCT) macular volume scans.METHODS: Macular OCT volume scans of left eyes from 17 subjects (8 patients with MS and 9 healthy controls) were automatically...

Optical coherence tomography for retinal imaging in multiple sclerosis.

Degenerative neurological and neuromuscular disease

Zimmermann H, Oberwahrenbrock T, Brandt AU, Paul F, Dörr J.
PMID: 32669908
Degener Neurol Neuromuscul Dis. 2014 Dec 09;4:153-162. doi: 10.2147/DNND.S73506. eCollection 2014.

Visual disturbances caused by inflammatory and demyelinating processes of the visual system, mainly in the optic nerve, are a common symptom in multiple sclerosis (MS). Optical coherence tomography (OCT) is a tool that is increasingly used for quantifying retinal...

Retinal damage in multiple sclerosis disease subtypes measured by high-resolution optical coherence tomography.

Multiple sclerosis international

Oberwahrenbrock T, Schippling S, Ringelstein M, Kaufhold F, Zimmermann H, Keser N, Young KL, Harmel J, Hartung HP, Martin R, Paul F, Aktas O, Brandt AU.
PMID: 22888431
Mult Scler Int. 2012;2012:530305. doi: 10.1155/2012/530305. Epub 2012 Jul 25.

Background. Optical coherence tomography (OCT) has facilitated characterisation of retinal alterations in MS patients. Only scarce and in part conflicting data exists on different MS subtypes. Objective. To analyse patterns of retinal changes in different subtypes of MS with...

Contribution of blood vessels to retinal nerve fiber layer thickness in NMOSD.

Neurology(R) neuroimmunology & neuroinflammation

Oertel FC, Zimmermann H, Mikolajczak J, Weinhold M, Kadas EM, Oberwahrenbrock T, Pache F, Bellmann-Strobl J, Ruprecht K, Paul F, Brandt AU.
PMID: 28451626
Neurol Neuroimmunol Neuroinflamm. 2017 Apr 18;4(3):e338. doi: 10.1212/NXI.0000000000000338. eCollection 2017 May.

No abstract available.

Visual dysfunction, but not retinal thinning, following anti-NMDA receptor encephalitis.

Neurology(R) neuroimmunology & neuroinflammation

Brandt AU, Oberwahrenbrock T, Mikolajczak J, Zimmermann H, Prüss H, Paul F, Finke C.
PMID: 26894203
Neurol Neuroimmunol Neuroinflamm. 2016 Feb 02;3(2):e198. doi: 10.1212/NXI.0000000000000198. eCollection 2016 Apr.

OBJECTIVE: To assess structural and functional changes in the afferent visual system following anti-NMDA receptor (NMDAR) encephalitis.METHODS: In this cross-sectional study including 31 patients after acute NMDAR encephalitis and matched healthy controls, visual function was assessed as high-contrast visual...

CuBe: parametric modeling of 3D foveal shape using cubic Bézier.

Biomedical optics express

Yadav SK, Motamedi S, Oberwahrenbrock T, Oertel FC, Polthier K, Paul F, Kadas EM, Brandt AU.
PMID: 28966857
Biomed Opt Express. 2017 Aug 22;8(9):4181-4199. doi: 10.1364/BOE.8.004181. eCollection 2017 Sep 01.

Optical coherence tomography (OCT) allows three-dimensional (3D) imaging of the retina, and is commonly used for assessing pathological changes of fovea and macula in many diseases. Many neuroinflammatory conditions are known to cause modifications to the fovea shape. In...

Spinocerebellar ataxia type 14: refining clinicogenetic diagnosis in a rare adult-onset disorder.

Annals of clinical and translational neurology

Schmitz-Hübsch T, Lux S, Bauer P, Brandt AU, Schlapakow E, Greschus S, Scheel M, Gärtner H, Kirlangic ME, Gras V, Timmann D, Synofzik M, Giorgetti A, Carloni P, Shah JN, Schöls L, Kopp U, Bußenius L, Oberwahrenbrock T, Zimmermann H, Pfueller C, Kadas EM, Rönnefarth M, Grosch AS, Endres M, Amunts K, Paul F, Doss S, Minnerop M.
PMID: 33739604
Ann Clin Transl Neurol. 2021 Apr;8(4):774-789. doi: 10.1002/acn3.51315. Epub 2021 Mar 19.

OBJECTIVES: Genetic variant classification is a challenge in rare adult-onset disorders as in SCA-PRKCG (prior spinocerebellar ataxia type 14) with mostly private conventional mutations and nonspecific phenotype. We here propose a refined approach for clinicogenetic diagnosis by including protein...

Showing 1 to 7 of 7 entries