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Showing 1 to 4 of 4 entries
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Pleiotropic vascular effects of ivabradine in streptozotocin-induced diabetes.

European journal of pharmacology

Kara Z, Güven B, Onay Besikci A, Yıldırım N, Altunay H.
PMID: 34906548
Eur J Pharmacol. 2022 Feb 05;916:174551. doi: 10.1016/j.ejphar.2021.174551. Epub 2021 Dec 11.

AIMS: Ivabradine (IVA) reduces heart rate (HR) by inhibiting hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in sinoatrial node. Studies suggest that IVA has other beneficial effects on cardiovascular system that are not related to its effect on HR such as...

Pleiotropic vascular effects of ivabradine in streptozotocin-induced diabetes.

European journal of pharmacology

Kara Z, Güven B, Onay Besikci A, Yıldırım N, Altunay H.
PMID: 34906548
Eur J Pharmacol. 2021 Dec 11;174551. doi: 10.1016/j.ejphar.2021.174551. Epub 2021 Dec 11.

AIMS: Ivabradine (IVA) reduces heart rate (HR) by inhibiting hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in sinoatrial node. Studies suggest that IVA has other beneficial effects on cardiovascular system that are not related to its effect on HR such as...

Synthesis and Pharmacologic Evaluation of Some Benzimidazole Acetohydrazide Derivatives as EGFR Inhibitors.

Turkish journal of pharmaceutical sciences

Demirel S, Ayhan Kilcigil G, Kara Z, Güven B, Onay Beşikci A.
PMID: 32454626
Turk J Pharm Sci. 2017 Dec;14(3):285-289. doi: 10.4274/tjps.24008. Epub 2017 Nov 20.

OBJECTIVES: In this study, some novel 2-(2-phenyl)-1MATERIALS AND METHODS: Compounds 1-12 were obtained by condensing 2-(2-phenyl)-1RESULTS: Following the structure elucidation, epidermal growth factor receptor kinase inhibitor activity was measured. The ADP-GloCONCLUSION: Almost all of the compounds' kinase inhibitor activities...

Pleiotropic vascular effects of ivabradine in streptozotocin-induced diabetes.

European journal of pharmacology

Kara Z, Güven B, Onay Besikci A, Yıldırım N, Altunay H.
PMID: 34906548
Eur J Pharmacol. 2021 Dec 11;174551. doi: 10.1016/j.ejphar.2021.174551. Epub 2021 Dec 11.

AIMS: Ivabradine (IVA) reduces heart rate (HR) by inhibiting hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in sinoatrial node. Studies suggest that IVA has other beneficial effects on cardiovascular system that are not related to its effect on HR such as...

Showing 1 to 4 of 4 entries