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Showing 1 to 12 of 22 entries
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Frontotemporal dementia and psychiatry.

International review of psychiatry (Abingdon, England)

Onyike CU, Huey ED.
PMID: 23611342
Int Rev Psychiatry. 2013 Apr;25(2):127-9. doi: 10.3109/09540261.2013.785169.

No abstract available.

Rheumatoid pannus presenting as a large epidural mass in the subaxial cervical spine: A case report.

Neuro-Chirurgie

Leclair NK, Knopf J, Baldwin M, Forouhar F, Onyiuke H.
PMID: 33667534
Neurochirurgie. 2022 Jan;68(1):129-132. doi: 10.1016/j.neuchi.2021.02.009. Epub 2021 Mar 02.

Rheumatoid arthritis (RA) is a debilitating inflammatory condition characterised by joint damage that affects the cervical spine most commonly at the atlantoaxial joint resulting in neck pain and myelopathy. The pathogenesis of RA involves the formation of a hyperplastic...

Characterization of Lifestyle in Spinocerebellar Ataxia Type 3 and Association with Disease Severity.

Movement disorders : official journal of the Movement Disorder Society

Hengel H, Martus P, Faber J, Garcia-Moreno H, Solanky N, Giunti P, Klockgether T, Reetz K, van de Warrenburg BP, Pereira de Almeida L, Santana MM, Januário C, Silva P, Thieme A, Infante J, de Vries J, Lima M, Ferreira AF, Bushara K, Jacobi H, Onyike C, Schmahmann JD, Hübener-Schmid J, Synofzik M, Schöls L.
PMID: 34713931
Mov Disord. 2021 Oct 29; doi: 10.1002/mds.28844. Epub 2021 Oct 29.

BACKGROUND: Lifestyle could influence the course of hereditary ataxias, but representative data are missing.OBJECTIVE: The objective of this study was to characterize lifestyle in spinocerebellar ataxia type 3 (SCA3) and investigate possible associations with disease parameters.METHODS: In a prospective...

The contribution of behavioral features to caregiver burden in FTLD spectrum disorders.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Silverman HE, Ake JM, Manoochehri M, Appleby BS, Brushaber D, Devick KL, Dickerson BC, Fields JA, Forsberg LK, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Kornak J, Lapid MI, Litvan I, Mackenzie IR, Mendez MF, Onyike CU, Pascual B, Tartaglia MC, Boeve BF, Boxer AL, Rosen HJ, Cosentino S, Huey ED, Barker MS, Goldman JS.
PMID: 34854532
Alzheimers Dement. 2021 Dec 02; doi: 10.1002/alz.12494. Epub 2021 Dec 02.

INTRODUCTION: Caregivers of patients with frontotemporal lobar degeneration (FTLD) spectrum disorders experience tremendous burden, which has been associated with the neuropsychiatric and behavioral features of the disorders.METHODS: In a sample of 558 participants with FTLD spectrum disorders, we performed...

The Longitudinal Early-onset Alzheimer's Disease Study (LEADS): Framework and methodology.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Apostolova LG, Aisen P, Eloyan A, Fagan A, Fargo KN, Foroud T, Gatsonis C, Grinberg LT, Jack CR, Kramer J, Koeppe R, Kukull WA, Murray ME, Nudelman K, Rumbaugh M, Toga A, Vemuri P, Trullinger A, Iaccarino L, Day GS, Graff-Radford NR, Honig LS, Jones DT, Masdeu J, Mendez M, Musiek E, Onyike CU, Rogalski E, Salloway S, Wolk DA, Wingo TS, Carrillo MC, Dickerson BC, Rabinovici GD.
PMID: 34018654
Alzheimers Dement. 2021 May 21; doi: 10.1002/alz.12350. Epub 2021 May 21.

Patients with early-onset Alzheimer's disease (EOAD) are commonly excluded from large-scale observational and therapeutic studies due to their young age, atypical presentation, or absence of pathogenic mutations. The goals of the Longitudinal EOAD Study (LEADS) are to (1) define...

Hippocampal sclerosis dementia: An amnesic variant of frontotemporal degeneration.

Dementia & neuropsychologia

Onyike CU, Pletnikova O, Sloane KL, Sullivan C, Troncoso JC, Rabins PV.
PMID: 24363834
Dement Neuropsychol. 2013 Mar 01;7(1):83-87. doi: 10.1590/s1980-57642013dn70100013.

OBJECTIVE: To describe characteristics of hippocampal sclerosis dementia.METHODS: Convenience sample of Hippocampal sclerosis dementia (HSD) recruited from the Johns Hopkins University Brain Resource Center. Twenty-four cases with post-mortem pathological diagnosis of hippocampal sclerosis dementia were reviewed for clinical characterization.RESULTS:...

Childless Elders in Assisted Living: Findings from the Maryland Assisted Living Study.

Journal of housing for the elderly

de Medeiros K, Rubinstein RL, Onyike CU, Johnston DM, Baker A, McNabney M, Lyketsos CG, Rosenblatt A, Samus QM.
PMID: 24729653
J Hous Elderly. 2013;27(1):206-220. doi: 10.1080/02763893.2012.754823.

We compared data drawn from a random sample of 399 current assisted living (AL) residents and a subsample of 222 newly admitted residents for two groups: childless AL residents and AL residents with children. The percentage of childless AL...

A toolbox to visually explore cerebellar shape changes in cerebellar disease and dysfunction.

Proceedings of SPIE--the International Society for Optical Engineering

Abulnaga SM, Yang Z, Carass A, Kansal K, Jedynak BM, Onyike CU, Ying SH, Prince JL.
PMID: 28479655
Proc SPIE Int Soc Opt Eng. 2016 Feb 27;9785. doi: 10.1117/12.2216584. Epub 2016 Mar 24.

The cerebellum plays an important role in motor control and is also involved in cognitive processes. Cerebellar function is specialized by location, although the exact topographic functional relationship is not fully understood. The spinocerebellar ataxias are a group of...

Neuroleptic discontinuation during dementia care: a recent trial and its implications for practice.

Nature clinical practice. Neurology

Onyike CU.
PMID: 18725920
Nat Clin Pract Neurol. 2008 Oct;4(10):528-9. doi: 10.1038/ncpneuro0884. Epub 2008 Aug 26.

No abstract available.

Landmark Based Shape Analysis for Cerebellar Ataxia Classification and Cerebellar Atrophy Pattern Visualization.

Proceedings of SPIE--the International Society for Optical Engineering

Yang Z, Abulnaga SM, Carass A, Kansal K, Jedynak BM, Onyike C, Ying SH, Prince JL.
PMID: 27303111
Proc SPIE Int Soc Opt Eng. 2016 Feb 27;9784. doi: 10.1117/12.2217313. Epub 2016 Mar 21.

Cerebellar dysfunction can lead to a wide range of movement disorders. Studying the cerebellar atrophy pattern associated with different cerebellar disease types can potentially help in diagnosis, prognosis, and treatment planning. In this paper, we present a landmark based...

The Longitudinal Early-onset Alzheimer's Disease Study (LEADS): Framework and methodology.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Apostolova LG, Aisen P, Eloyan A, Fagan A, Fargo KN, Foroud T, Gatsonis C, Grinberg LT, Jack CR, Kramer J, Koeppe R, Kukull WA, Murray ME, Nudelman K, Rumbaugh M, Toga A, Vemuri P, Trullinger A, Iaccarino L, Day GS, Graff-Radford NR, Honig LS, Jones DT, Masdeu J, Mendez M, Musiek E, Onyike CU, Rogalski E, Salloway S, Wolk DA, Wingo TS, Carrillo MC, Dickerson BC, Rabinovici GD.
PMID: 34018654
Alzheimers Dement. 2021 May 21; doi: 10.1002/alz.12350. Epub 2021 May 21.

Patients with early-onset Alzheimer's disease (EOAD) are commonly excluded from large-scale observational and therapeutic studies due to their young age, atypical presentation, or absence of pathogenic mutations. The goals of the Longitudinal EOAD Study (LEADS) are to (1) define...

The contribution of behavioral features to caregiver burden in FTLD spectrum disorders.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Silverman HE, Ake JM, Manoochehri M, Appleby BS, Brushaber D, Devick KL, Dickerson BC, Fields JA, Forsberg LK, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Kornak J, Lapid MI, Litvan I, Mackenzie IR, Mendez MF, Onyike CU, Pascual B, Tartaglia MC, Boeve BF, Boxer AL, Rosen HJ, Cosentino S, Huey ED, Barker MS, Goldman JS.
PMID: 34854532
Alzheimers Dement. 2021 Dec 02; doi: 10.1002/alz.12494. Epub 2021 Dec 02.

INTRODUCTION: Caregivers of patients with frontotemporal lobar degeneration (FTLD) spectrum disorders experience tremendous burden, which has been associated with the neuropsychiatric and behavioral features of the disorders.METHODS: In a sample of 558 participants with FTLD spectrum disorders, we performed...

Showing 1 to 12 of 22 entries