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Complementary and synergistic therapeutic effects of compounds found in Kampo medicine: analysis of daikenchuto.

Frontiers in pharmacology

Kono T, Shimada M, Yamamoto M, Kaneko A, Oomiya Y, Kubota K, Kase Y, Lee K, Uezono Y.
PMID: 26300774
Front Pharmacol. 2015 Aug 04;6:159. doi: 10.3389/fphar.2015.00159. eCollection 2015.

Herbal medicines have been used in Japan for more than 1500 years and traditional Japanese medicines (Kampo medicines) are now fully integrated into the modern healthcare system. In total, 148 Kampo formulae are officially approved as prescription drugs and...

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Kono T, Shimada M, Yamamoto M, et al. Complementary and synergistic therapeutic effects of compounds found in Kampo medicine: analysis of daikenchuto. Front Pharmacol. 2015;6:159doi: 10.3389/fphar.2015.00159.
Kono, T., Shimada, M., Yamamoto, M., Kaneko, A., Oomiya, Y., Kubota, K., Kase, Y., Lee, K., & Uezono, Y. (2015). Complementary and synergistic therapeutic effects of compounds found in Kampo medicine: analysis of daikenchuto. Frontiers in pharmacology, 6159. https://doi.org/10.3389/fphar.2015.00159
Kono, Toru, et al. "Complementary and synergistic therapeutic effects of compounds found in Kampo medicine: analysis of daikenchuto." Frontiers in pharmacology vol. 6 (2015): 159. doi: https://doi.org/10.3389/fphar.2015.00159
Kono T, Shimada M, Yamamoto M, Kaneko A, Oomiya Y, Kubota K, Kase Y, Lee K, Uezono Y. Complementary and synergistic therapeutic effects of compounds found in Kampo medicine: analysis of daikenchuto. Front Pharmacol. 2015 Aug 04;6:159. doi: 10.3389/fphar.2015.00159. eCollection 2015. PMID: 26300774; PMCID: PMC4523940.
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Associations in tumor infiltrating lymphocytes between clinicopathological factors and clinical outcomes in estrogen receptor-positive/human epidermal growth factor receptor type 2 negative breast cancer.

Oncology letters

Miyoshi Y, Shien T, Ogiya A, Ishida N, Yamazaki K, Horii R, Horimoto Y, Masuda N, Yasojima H, Inao T, Osako T, Takahashi M, Tomioka N, Wanifuchi-Endo Y, Hosoda M, Doihara H, Yamashita H.
PMID: 30675282
Oncol Lett. 2019 Feb;17(2):2177-2186. doi: 10.3892/ol.2018.9853. Epub 2018 Dec 19.

The value of assessing tumor infiltrating lymphocytes (TILs) in estrogen receptor (ER) positive/human epidermal growth factor receptor type 2 (HER2) negative breast cancer has yet to be determined. In the present study, a total of 184 cases with early...

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Miyoshi Y, Shien T, Ogiya A, et al. Associations in tumor infiltrating lymphocytes between clinicopathological factors and clinical outcomes in estrogen receptor-positive/human epidermal growth factor receptor type 2 negative breast cancer. Oncol Lett. 2018;17(2):2177-2186doi: 10.3892/ol.2018.9853.
Miyoshi, Y., Shien, T., Ogiya, A., Ishida, N., Yamazaki, K., Horii, R., Horimoto, Y., Masuda, N., Yasojima, H., Inao, T., Osako, T., Takahashi, M., Tomioka, N., Wanifuchi-Endo, Y., Hosoda, M., Doihara, H., & Yamashita, H. (2019). Associations in tumor infiltrating lymphocytes between clinicopathological factors and clinical outcomes in estrogen receptor-positive/human epidermal growth factor receptor type 2 negative breast cancer. Oncology letters, 17(2), 2177-2186. https://doi.org/10.3892/ol.2018.9853
Miyoshi, Yuichiro, et al. "Associations in tumor infiltrating lymphocytes between clinicopathological factors and clinical outcomes in estrogen receptor-positive/human epidermal growth factor receptor type 2 negative breast cancer." Oncology letters vol. 17,2 (2019): 2177-2186. doi: https://doi.org/10.3892/ol.2018.9853
Miyoshi Y, Shien T, Ogiya A, Ishida N, Yamazaki K, Horii R, Horimoto Y, Masuda N, Yasojima H, Inao T, Osako T, Takahashi M, Tomioka N, Wanifuchi-Endo Y, Hosoda M, Doihara H, Yamashita H. Associations in tumor infiltrating lymphocytes between clinicopathological factors and clinical outcomes in estrogen receptor-positive/human epidermal growth factor receptor type 2 negative breast cancer. Oncol Lett. 2019 Feb;17(2):2177-2186. doi: 10.3892/ol.2018.9853. Epub 2018 Dec 19. PMID: 30675282; PMCID: PMC6341802.
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Molecular evolutionary engineering of xylose isomerase to improve its catalytic activity and performance of micro-aerobic glucose/xylose co-fermentation in .

Biotechnology for biofuels

Seike T, Kobayashi Y, Sahara T, Ohgiya S, Kamagata Y, Fujimori KE.
PMID: 31178927
Biotechnol Biofuels. 2019 Jun 06;12:139. doi: 10.1186/s13068-019-1474-z. eCollection 2019.

BACKGROUND: Expression of d-xylose isomerase having high catalytic activity in RESULTS: Eight XI genes shown to have good expression in CONCLUSIONS: This study demonstrated that

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Seike T, Kobayashi Y, Sahara T, et al. Molecular evolutionary engineering of xylose isomerase to improve its catalytic activity and performance of micro-aerobic glucose/xylose co-fermentation in . Biotechnol Biofuels. 2019;12:139doi: 10.1186/s13068-019-1474-z.
Seike, T., Kobayashi, Y., Sahara, T., Ohgiya, S., Kamagata, Y., & Fujimori, K. E. (2019). Molecular evolutionary engineering of xylose isomerase to improve its catalytic activity and performance of micro-aerobic glucose/xylose co-fermentation in . Biotechnology for biofuels, 12139. https://doi.org/10.1186/s13068-019-1474-z
Seike, Taisuke, et al. "Molecular evolutionary engineering of xylose isomerase to improve its catalytic activity and performance of micro-aerobic glucose/xylose co-fermentation in ." Biotechnology for biofuels vol. 12 (2019): 139. doi: https://doi.org/10.1186/s13068-019-1474-z
Seike T, Kobayashi Y, Sahara T, Ohgiya S, Kamagata Y, Fujimori KE. Molecular evolutionary engineering of xylose isomerase to improve its catalytic activity and performance of micro-aerobic glucose/xylose co-fermentation in . Biotechnol Biofuels. 2019 Jun 06;12:139. doi: 10.1186/s13068-019-1474-z. eCollection 2019. PMID: 31178927; PMCID: PMC6551904.
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Anti-tumor activity of the pan-RAF inhibitor TAK-580 in combination with KPT-330 (selinexor) in multiple myeloma.

International journal of hematology

Suzuki R, Kitamura Y, Ogiya D, Ogawa Y, Kawada H, Ando K.
PMID: 34741230
Int J Hematol. 2021 Nov 05; doi: 10.1007/s12185-021-03244-1. Epub 2021 Nov 05.

RAS/RAF/MEK/ERK pathway inhibitors exhibit significant anti-tumor effects against various tumor types, including multiple myeloma (MM), and they are predicted to play a pivotal role in precision medicine. The XPO1 inhibitor KPT-330 has also exhibited promising efficacy in combination with...

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Suzuki R, Kitamura Y, Ogiya D, et al. Anti-tumor activity of the pan-RAF inhibitor TAK-580 in combination with KPT-330 (selinexor) in multiple myeloma. Int J Hematol. 2021;doi: 10.1007/s12185-021-03244-1.
Suzuki, R., Kitamura, Y., Ogiya, D., Ogawa, Y., Kawada, H., & Ando, K. (2021). Anti-tumor activity of the pan-RAF inhibitor TAK-580 in combination with KPT-330 (selinexor) in multiple myeloma. International journal of hematology, . https://doi.org/10.1007/s12185-021-03244-1
Suzuki, Rikio, et al. "Anti-tumor activity of the pan-RAF inhibitor TAK-580 in combination with KPT-330 (selinexor) in multiple myeloma." International journal of hematology vol. (2021). doi: https://doi.org/10.1007/s12185-021-03244-1
Suzuki R, Kitamura Y, Ogiya D, Ogawa Y, Kawada H, Ando K. Anti-tumor activity of the pan-RAF inhibitor TAK-580 in combination with KPT-330 (selinexor) in multiple myeloma. Int J Hematol. 2021 Nov 05; doi: 10.1007/s12185-021-03244-1. Epub 2021 Nov 05. PMID: 34741230.
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Current status of MRI-guided vacuum-assisted breast biopsy in Japan.

Breast cancer (Tokyo, Japan)

Takahama N, Tozaki M, Ohgiya Y.
PMID: 32632846
Breast Cancer. 2021 Nov;28(6):1188-1194. doi: 10.1007/s12282-020-01107-x. Epub 2020 Jul 06.

In April 2018, the national health insurance coverage of MRI-guided vacuum-assisted breast biopsy (VAB) was instituted with the application of the Japan Breast Cancer Society. Although MRI-guided VAB has been considered as a special procedure for a long time,...

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Takahama N, Tozaki M, Ohgiya Y. Current status of MRI-guided vacuum-assisted breast biopsy in Japan. Breast Cancer. 2020;28(6):1188-1194doi: 10.1007/s12282-020-01107-x.
Takahama, N., Tozaki, M., & Ohgiya, Y. (2021). Current status of MRI-guided vacuum-assisted breast biopsy in Japan. Breast cancer (Tokyo, Japan), 28(6), 1188-1194. https://doi.org/10.1007/s12282-020-01107-x
Takahama, Noritsugu, et al. "Current status of MRI-guided vacuum-assisted breast biopsy in Japan." Breast cancer (Tokyo, Japan) vol. 28,6 (2021): 1188-1194. doi: https://doi.org/10.1007/s12282-020-01107-x
Takahama N, Tozaki M, Ohgiya Y. Current status of MRI-guided vacuum-assisted breast biopsy in Japan. Breast Cancer. 2021 Nov;28(6):1188-1194. doi: 10.1007/s12282-020-01107-x. Epub 2020 Jul 06. PMID: 32632846.
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Effectiveness of empirical anti-pseudomonal antibiotics for recurrent COPD exacerbation: a multicenter retrospective cohort study.

Scientific reports

Shiroshita A, Miyakoshi C, Tsutsumi S, Shiba H, Shirakawa C, Sato K, Matsushita S, Kimura Y, Tomii K, Ohgiya M, Kataoka Y.
PMID: 34625632
Sci Rep. 2021 Oct 08;11(1):20066. doi: 10.1038/s41598-021-99640-y.

Although frequent chronic obstructive pulmonary disease (COPD) exacerbation has been associated with the isolation of Pseudomonas aeruginosa (PA) in sputum cultures, it remains unknown whether the empirical use of anti-pseudomonal antibiotics can improve outcomes in patients with frequent COPD...

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Shiroshita A, Miyakoshi C, Tsutsumi S, et al. Effectiveness of empirical anti-pseudomonal antibiotics for recurrent COPD exacerbation: a multicenter retrospective cohort study. Sci Rep. 2021;11(1):20066doi: 10.1038/s41598-021-99640-y.
Shiroshita, A., Miyakoshi, C., Tsutsumi, S., Shiba, H., Shirakawa, C., Sato, K., Matsushita, S., Kimura, Y., Tomii, K., Ohgiya, M., & Kataoka, Y. (2021). Effectiveness of empirical anti-pseudomonal antibiotics for recurrent COPD exacerbation: a multicenter retrospective cohort study. Scientific reports, 11(1), 20066. https://doi.org/10.1038/s41598-021-99640-y
Shiroshita, Akihiro, et al. "Effectiveness of empirical anti-pseudomonal antibiotics for recurrent COPD exacerbation: a multicenter retrospective cohort study." Scientific reports vol. 11,1 (2021): 20066. doi: https://doi.org/10.1038/s41598-021-99640-y
Shiroshita A, Miyakoshi C, Tsutsumi S, Shiba H, Shirakawa C, Sato K, Matsushita S, Kimura Y, Tomii K, Ohgiya M, Kataoka Y. Effectiveness of empirical anti-pseudomonal antibiotics for recurrent COPD exacerbation: a multicenter retrospective cohort study. Sci Rep. 2021 Oct 08;11(1):20066. doi: 10.1038/s41598-021-99640-y. PMID: 34625632; PMCID: PMC8501095.
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A successful pregnancy and delivery outcome for a 46-year-old woman following .

Reproductive medicine and biology

Yoshida H, Oomiya Y, Sato T, Aono N, Araki Y.
PMID: 29699182
Reprod Med Biol. 2004 Mar 30;3(1):39-42. doi: 10.1111/j.1447-0578.2004.00050.x. eCollection 2004 Mar.

No abstract available.

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Yoshida H, Oomiya Y, Sato T, et al. A successful pregnancy and delivery outcome for a 46-year-old woman following . Reprod Med Biol. 2004;3(1):39-42doi: 10.1111/j.1447-0578.2004.00050.x.
Yoshida, H., Oomiya, Y., Sato, T., Aono, N., & Araki, Y. (2004). A successful pregnancy and delivery outcome for a 46-year-old woman following . Reproductive medicine and biology, 3(1), 39-42. https://doi.org/10.1111/j.1447-0578.2004.00050.x
Yoshida, Hiroaki, et al. "A successful pregnancy and delivery outcome for a 46-year-old woman following ." Reproductive medicine and biology vol. 3,1 (2004): 39-42. doi: https://doi.org/10.1111/j.1447-0578.2004.00050.x
Yoshida H, Oomiya Y, Sato T, Aono N, Araki Y. A successful pregnancy and delivery outcome for a 46-year-old woman following . Reprod Med Biol. 2004 Mar 30;3(1):39-42. doi: 10.1111/j.1447-0578.2004.00050.x. eCollection 2004 Mar. PMID: 29699182; PMCID: PMC5904586.
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PRDM14 is overexpressed in chronic pancreatitis prior to pancreatic cancer.

FEBS open bio

Moriya C, Imai K, Taniguchi H.
PMID: 30338223
FEBS Open Bio. 2018 Sep 17;8(10):1733-1741. doi: 10.1002/2211-5463.12519. eCollection 2018 Oct.

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and lethal cancer that is typically diagnosed at a later stage with metastases and is difficult to treat. Therefore, investigating the mechanism of PDAC initiation is important to aid early-stage cancer detection....

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Moriya C, Imai K, Taniguchi H. PRDM14 is overexpressed in chronic pancreatitis prior to pancreatic cancer. FEBS Open Bio. 2018;8(10):1733-1741doi: 10.1002/2211-5463.12519.
Moriya, C., Imai, K., & Taniguchi, H. (2018). PRDM14 is overexpressed in chronic pancreatitis prior to pancreatic cancer. FEBS open bio, 8(10), 1733-1741. https://doi.org/10.1002/2211-5463.12519
Moriya, Chiharu, et al. "PRDM14 is overexpressed in chronic pancreatitis prior to pancreatic cancer." FEBS open bio vol. 8,10 (2018): 1733-1741. doi: https://doi.org/10.1002/2211-5463.12519
Moriya C, Imai K, Taniguchi H. PRDM14 is overexpressed in chronic pancreatitis prior to pancreatic cancer. FEBS Open Bio. 2018 Sep 17;8(10):1733-1741. doi: 10.1002/2211-5463.12519. eCollection 2018 Oct. PMID: 30338223; PMCID: PMC6168686.
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Comparison of immune microenvironments between primary tumors and brain metastases in patients with breast cancer.

Oncotarget

Ogiya R, Niikura N, Kumaki N, Yasojima H, Iwasa T, Kanbayashi C, Oshitanai R, Tsuneizumi M, Watanabe KI, Matsui A, Fujisawa T, Saji S, Masuda N, Tokuda Y, Iwata H.
PMID: 29262592
Oncotarget. 2017 Oct 27;8(61):103671-103681. doi: 10.18632/oncotarget.22110. eCollection 2017 Nov 28.

BACKGROUND: Immune checkpoint inhibitors are reported to be effective in patients with brain metastases. However, detailed characteristics of the brain metastasis immune microenvironment remain unexplored.RESULTS: The median tumor-infiltrating lymphocyte (TIL) category in brain metastases was 5% (1-70%). In 46...

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Ogiya R, Niikura N, Kumaki N, et al. Comparison of immune microenvironments between primary tumors and brain metastases in patients with breast cancer. Oncotarget. 2017;8(61):103671-103681doi: 10.18632/oncotarget.22110.
Ogiya, R., Niikura, N., Kumaki, N., Yasojima, H., Iwasa, T., Kanbayashi, C., Oshitanai, R., Tsuneizumi, M., Watanabe, K. I., Matsui, A., Fujisawa, T., Saji, S., Masuda, N., Tokuda, Y., & Iwata, H. (2017). Comparison of immune microenvironments between primary tumors and brain metastases in patients with breast cancer. Oncotarget, 8(61), 103671-103681. https://doi.org/10.18632/oncotarget.22110
Ogiya, Rin, et al. "Comparison of immune microenvironments between primary tumors and brain metastases in patients with breast cancer." Oncotarget vol. 8,61 (2017): 103671-103681. doi: https://doi.org/10.18632/oncotarget.22110
Ogiya R, Niikura N, Kumaki N, Yasojima H, Iwasa T, Kanbayashi C, Oshitanai R, Tsuneizumi M, Watanabe KI, Matsui A, Fujisawa T, Saji S, Masuda N, Tokuda Y, Iwata H. Comparison of immune microenvironments between primary tumors and brain metastases in patients with breast cancer. Oncotarget. 2017 Oct 27;8(61):103671-103681. doi: 10.18632/oncotarget.22110. eCollection 2017 Nov 28. PMID: 29262592; PMCID: PMC5732758.
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Spontaneous periodic pulsation of contact line in oil/water system--frequency control with divalent cations and applied voltage.

Journal of colloid and interface science

Oomiya K, Mori D, Ban T, Shioi A.
PMID: 21784428
J Colloid Interface Sci. 2011 Oct 15;362(2):553-9. doi: 10.1016/j.jcis.2011.06.075. Epub 2011 Jul 07.

Periodic oscillatory change of hydrophilicity (or hydrophobicity) of a glass surface was studied. A glass capillary was immersed normally at an oil/water interface. The water phase contained the cationic surfactant trimethyloctadecylammoniumchloride, and the oil phase contained bis(2ethylhexyl) phosphate. Adsorption...

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Oomiya K, Mori D, Ban T, et al. Spontaneous periodic pulsation of contact line in oil/water system--frequency control with divalent cations and applied voltage. J Colloid Interface Sci. 2011;362(2):553-9doi: 10.1016/j.jcis.2011.06.075.
Oomiya, K., Mori, D., Ban, T., & Shioi, A. (2011). Spontaneous periodic pulsation of contact line in oil/water system--frequency control with divalent cations and applied voltage. Journal of colloid and interface science, 362(2), 553-9. https://doi.org/10.1016/j.jcis.2011.06.075
Oomiya, Katsuhito, et al. "Spontaneous periodic pulsation of contact line in oil/water system--frequency control with divalent cations and applied voltage." Journal of colloid and interface science vol. 362,2 (2011): 553-9. doi: https://doi.org/10.1016/j.jcis.2011.06.075
Oomiya K, Mori D, Ban T, Shioi A. Spontaneous periodic pulsation of contact line in oil/water system--frequency control with divalent cations and applied voltage. J Colloid Interface Sci. 2011 Oct 15;362(2):553-9. doi: 10.1016/j.jcis.2011.06.075. Epub 2011 Jul 07. PMID: 21784428.
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Nutritional characteristics of a neoglycoprotein, casein modified covalently by glucose.

The Journal of nutritional biochemistry

Furuichi Y, Oogida T, Mitsui C, Matsuno M, Takahashi T.
PMID: 15539204
J Nutr Biochem. 1990 Apr;1(4):196-9. doi: 10.1016/0955-2863(90)90106-u.

Glucose was combined covalently with the epsilon-amino groups of lysyl residues of bovine casein in the presence of sodium cyanoborohydride as a reducing reagent by reductive alkylation, forming stable secondary amine linkages. Solubility characteristics and nutritional values of the...

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Furuichi Y, Oogida T, Mitsui C, et al. Nutritional characteristics of a neoglycoprotein, casein modified covalently by glucose. J Nutr Biochem. 1990;1(4):196-9doi: 10.1016/0955-2863(90)90106-u.
Furuichi, Y., Oogida, T., Mitsui, C., Matsuno, M., & Takahashi, T. (1990). Nutritional characteristics of a neoglycoprotein, casein modified covalently by glucose. The Journal of nutritional biochemistry, 1(4), 196-9. https://doi.org/10.1016/0955-2863(90)90106-u
Furuichi, Y, et al. "Nutritional characteristics of a neoglycoprotein, casein modified covalently by glucose." The Journal of nutritional biochemistry vol. 1,4 (1990): 196-9. doi: https://doi.org/10.1016/0955-2863(90)90106-u
Furuichi Y, Oogida T, Mitsui C, Matsuno M, Takahashi T. Nutritional characteristics of a neoglycoprotein, casein modified covalently by glucose. J Nutr Biochem. 1990 Apr;1(4):196-9. doi: 10.1016/0955-2863(90)90106-u. PMID: 15539204.
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N(2)O induces mitotic polyploidization in anther somatic cells and restores fertility in sterile interspecific hybrid lilies.

Breeding science

Nukui S, Kitamura S, Hioki T, Ootsuka H, Miyoshi K, Satou T, Takatori Y, Oomiya T, Okazaki K.
PMID: 23136469
Breed Sci. 2011 Dec;61(4):327-37. doi: 10.1270/jsbbs.61.327. Epub 2011 Dec 15.

Fertile plants undergoing male gametogenesis can be treated with nitrous oxide (N(2)O) gas to obtain 2n male gametes. N(2)O treatment is also expected to restore the fertility of interspecific hybrids through meiotic restitution or mitotic amphidiploidization. However, this technique...

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Nukui S, Kitamura S, Hioki T, et al. N(2)O induces mitotic polyploidization in anther somatic cells and restores fertility in sterile interspecific hybrid lilies. Breed Sci. 2011;61(4):327-37doi: 10.1270/jsbbs.61.327.
Nukui, S., Kitamura, S., Hioki, T., Ootsuka, H., Miyoshi, K., Satou, T., Takatori, Y., Oomiya, T., & Okazaki, K. (2011). N(2)O induces mitotic polyploidization in anther somatic cells and restores fertility in sterile interspecific hybrid lilies. Breeding science, 61(4), 327-37. https://doi.org/10.1270/jsbbs.61.327
Nukui, Shotarou, et al. "N(2)O induces mitotic polyploidization in anther somatic cells and restores fertility in sterile interspecific hybrid lilies." Breeding science vol. 61,4 (2011): 327-37. doi: https://doi.org/10.1270/jsbbs.61.327
Nukui S, Kitamura S, Hioki T, Ootsuka H, Miyoshi K, Satou T, Takatori Y, Oomiya T, Okazaki K. N(2)O induces mitotic polyploidization in anther somatic cells and restores fertility in sterile interspecific hybrid lilies. Breed Sci. 2011 Dec;61(4):327-37. doi: 10.1270/jsbbs.61.327. Epub 2011 Dec 15. PMID: 23136469; PMCID: PMC3406768.
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