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Showing 1 to 12 of 46 entries
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Xylitol toxicosis and serotonin-like syndrome occurring simultaneously in a dog secondary to ingestion of Natrol 5-HTP Fast Dissolve Tablets.

Clinical case reports

Ortolani JM, Bellis TJ, Griego MD.
PMID: 30655997
Clin Case Rep. 2018 Nov 08;7(1):5-10. doi: 10.1002/ccr3.1869. eCollection 2019 Jan.

Xylitol and serotonergic compounds are included in the manufacture of numerous over-the-counter products. Both compounds have been documented to cause toxicosis in dogs. This report details the first case of simultaneous xylitol toxicosis and serotonin-like syndrome in a dog,...

Emergency Medicine Residency Curricular Innovations: Creating a Virtual Emergency Medicine Didactic Conference.

AEM education and training

Rotoli J, Bodkin R, Pereira J, Adler D, Lou V, Moriarty J, Williams J, Nobay F.
PMID: 32704598
AEM Educ Train. 2020 Jun 13;4(3):270-274. doi: 10.1002/aet2.10477. eCollection 2020 Jul.

Currently, there is a pandemic forcing social distancing and, consequently, traditional in-person education must shift to a virtual curriculum to protect all parties and continue professional development. Recognizing that not all emergency medicine (EM) content can be taught through...

Urine Endocannabinoids as Novel Non-Invasive Biomarkers for Bladder Cancer at Early Stage.

Cancers

Vago R, Ravelli A, Bettiga A, Casati S, Lavorgna G, Benigni F, Salonia A, Montorsi F, Orioli M, Ciuffreda P, Ottria R.
PMID: 32260109
Cancers (Basel). 2020 Apr 03;12(4). doi: 10.3390/cancers12040870.

Due to the involvement of the endocannabinoid system (ECS) in cancer onset and progression and the less studied connection between ECS and bladder cancer, here an evaluation of the ECS modifications associated with bladder cancer is reported. Urine samples...

Prevalence of microcephaly: the Latin American Network of Congenital Malformations 2010-2017.

BMJ paediatrics open

Morris J, Orioli IM, Benavides-Lara A, de la Paz Barboza-Arguello M, Tapia MAC, de França GVA, Groisman B, Holguin J, Hurtado-Villa PM, Ibarra Ramirez M, Mellado C, Pardo R, Pastora Bucardo DM, Rodríguez C, Zarante I, Limb E, Dolk H.
PMID: 34901471
BMJ Paediatr Open. 2021 Nov 23;5(1):e001235. doi: 10.1136/bmjpo-2021-001235. eCollection 2021.

OBJECTIVE: The Latin American Network of Congenital Malformations: ReLAMC was established in 2017 to provide accurate congenital anomaly surveillance. This study used data from ReLAMC registries to quantify the prevalence of microcephaly from 2010 to 2017 (before, during and...

Organic Cation Transporters (OCTs) in EpiAirway™, A Cellular Model of Normal Human Bronchial Epithelium.

Biomedicines

Barilli A, Visigalli R, Ferrari F, Di Lascia M, Riccardi B, Puccini P, Dall'Asta V, Rotoli BM.
PMID: 32438722
Biomedicines. 2020 May 19;8(5). doi: 10.3390/biomedicines8050127.

Organic cation transporters (OCTs) and novel organic cation transporters (OCTNs) are responsible for drug delivery in the intestine and kidney; in the lung, OCTs mediate inhaled drugs' transport, although their physiological role in airways remains poorly understood. The studies...

Drug Design: Where We Are and Future Prospects.

Molecules (Basel, Switzerland)

Zagotto G, Bortoli M.
PMID: 34834152
Molecules. 2021 Nov 22;26(22). doi: 10.3390/molecules26227061.

Medicinal chemistry is facing new challenges in approaching precision medicine. Several powerful new tools or improvements of already used tools are now available to medicinal chemists to help in the process of drug discovery, from a hit molecule to...

WE43 and WE43-T5 Mg alloys screws tested in-vitro cellular adhesion and differentiation assay and in-vivo histomorphologic analysis in an ovine model.

Journal of biomaterials applications

Torroni A, Witek L, Fahliogullari HP, Bortoli JP, Ibrahim A, Hacquebord J, Gupta N, Coelho P.
PMID: 32903065
J Biomater Appl. 2021 Mar;35(8):901-911. doi: 10.1177/0885328220956788. Epub 2020 Sep 09.

WE43 Mg alloy proved to be an ideal candidate for production of resorbable implants in both clinical and trial settings. In previous studies we tested biocompatibility and degradation properties of WE43 (as-cast) and artificially aged (WE43-T5) Mg alloys in...

Detection of Streptococcus mutans Genomic DNA in Human DNA Samples Extracted from Saliva and Blood.

ISRN dentistry

Vieira AR, Deeley KB, Callahan NF, Noel JB, Anjomshoaa I, Carricato WM, Schulhof LP, Desensi RS, Gandhi P, Resick JM, Brandon CA, Rozhon C, Patir A, Yildirim M, Poletta FA, Mereb JC, Letra A, Menezes R, Wendell S, Lopez-Camelo JS, Castilla EE, Orioli IM, Seymen F, Weyant RJ, Crout R, McNeil DW, Modesto A, Marazita ML.
PMID: 21731912
ISRN Dent. 2011;2011:543561. doi: 10.5402/2011/543561. Epub 2011 Apr 10.

Caries is a multifactorial disease, and studies aiming to unravel the factors modulating its etiology must consider all known predisposing factors. One major factor is bacterial colonization, and Streptococcus mutans is the main microorganism associated with the initiation of...

Beare-Stevenson cutis gyrata syndrome: A new case of a c.1124C↷G (Y375C) mutation in the FGFR2 gene.

Molecular medicine reports

Fonseca RF, Costa-Lima MA, Pereira ET, Castilla EE, Orioli IM.
PMID: 21479481
Mol Med Rep. 2008 Sep-Oct;1(5):753-5. doi: 10.3892/mmr_00000024.

Beare-Stevenson syndrome (BSS) (MIM#123790) is a rare disorder characterized by craniofacial anomalies and cutis gyrata associated with anogenital anomalies and prominent umbilical stump. There are few reports on the syndrome, and molecular analysis has revealed the involvement of two...

Determination of lead and cadmium in titanium dioxide by differential pulse anodic stripping voltammetry.

Talanta

Panigati M, Piccone M, D'Alfonso G, Orioli M, Carini M.
PMID: 18968775
Talanta. 2002 Sep 12;58(3):481-8. doi: 10.1016/s0039-9140(02)00251-5.

A procedure for the simultaneous determination of lead and cadmium in TiO(2) by differential pulse anodic stripping voltammetry (ASV) has been developed. The key feature of the method is the use of triethanolamine (TEA) to remove titanium interference: TiO(2)...

Family-based genome-wide association study in Patagonia confirms the association of the DMD locus and cleft lip and palate.

European journal of oral sciences

Fonseca RF, de Carvalho FM, Poletta FA, Montaner D, Dopazo J, Mereb JC, Moreira MAM, Seuanez HN, Vieira AR, Castilla EE, Orioli IM.
PMID: 26331285
Eur J Oral Sci. 2015 Oct;123(5):381-384. doi: 10.1111/eos.12212. Epub 2015 Sep 01.

The etiology of cleft lip with or without cleft palate (CL±P) is complex and heterogeneous, and multiple genetic and environmental factors are involved. Some candidate genes reported to be associated with oral clefts are located on the X chromosome....

Molecular analysis of holoprosencephaly in South America.

Genetics and molecular biology

Savastano CP, El-Jaick KB, Costa-Lima MA, Abath CM, Bianca S, Cavalcanti DP, Félix TM, Scarano G, Llerena JC, Vargas FR, Moreira MÂ, Seuánez HN, Castilla EE, Orioli IM.
PMID: 24764759
Genet Mol Biol. 2014 Mar;37(1):250-62. doi: 10.1590/s1415-47572014000200011.

Holoprosencephaly (HPE) is a spectrum of brain and facial malformations primarily reflecting genetic factors, such as chromosomal abnormalities and gene mutations. Here, we present a clinical and molecular analysis of 195 probands with HPE or microforms; approximately 72% of...

Showing 1 to 12 of 46 entries