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Comparison of conventional dried blood spots and volumetric absorptive microsampling for tacrolimus and mycophenolic acid determination.

Journal of pharmaceutical and biomedical analysis

Paniagua-González L, Lendoiro E, Otero-Antón E, López-Rivadulla M, de-Castro-Ríos A, Cruz A.
PMID: 34735994
J Pharm Biomed Anal. 2022 Jan 20;208:114443. doi: 10.1016/j.jpba.2021.114443. Epub 2021 Oct 26.

Therapeutic drug monitoring (TDM) of immunosuppressants is essential to avoid either rejection or toxicity after solid organ transplantations. Capillary microsampling approaches are an outstanding alternative to conventional venous sampling for TDM (easy and non-invasive collection, enabling self-sampling, and cost-saving...

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