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Showing 1 to 12 of 102 entries
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Coefficients of inbreeding and homozygosity in recurrent selection: the one-locus case.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

Cain RL, Hinkelmann K.
PMID: 24435909
Theor Appl Genet. 1970 Jan;40(7):327-35. doi: 10.1007/BF00264576.

For selection programs which can be represented by successive self-select-intercross cycles (such as recurrent selection or reciprocal recurrent selection) general recurrence formulae are developed for obtaining the coefficients of inbreeding and homozygosity in each cycle. The formula for the...

"On-Droplet" Chemistry: The Cycloaddition of Diethyl Azodicarboxylate and Quadricyclane.

Angewandte Chemie (International ed. in English)

Bain RM, Sathyamoorthi S, Zare RN.
PMID: 28992393
Angew Chem Int Ed Engl. 2017 Nov 20;56(47):15083-15087. doi: 10.1002/anie.201708413. Epub 2017 Oct 24.

Sharpless and co-workers previously studied the [2σ+2σ+2π] cycloaddition of diethyl azodicarboxylate (DEAD) and quadricyclane and reported that the addition of water to the neat reagents caused an acceleration in the reaction rate, giving birth to what has been called...

Restrictions on Soviet scientists.

Nature

Cahn RW.
PMID: 16058568
Nature. 1970 Oct 31;228(5270):485. doi: 10.1038/228485a0.

No abstract available.

Man and the machine.

British medical journal

BAIN CW.
PMID: 18133680
Br Med J. 1949 Jul 02;2(4617):1-6. doi: 10.1136/bmj.2.4617.1.

No abstract available.

PERICARDITIS AND COMPLETE HEART BLOCK DURING THIOURACIL THERAPY.

British heart journal

Bain CW.
PMID: 18609989
Br Heart J. 1945 Jan;7(1):49-51. doi: 10.1136/hrt.7.1.49.

No abstract available.

Update on the management of chronic rhinosinusitis.

Infection and drug resistance

Cain RB, Lal D.
PMID: 23378777
Infect Drug Resist. 2013;6:1-14. doi: 10.2147/IDR.S26134. Epub 2013 Jan 23.

Chronic rhinosinusitis (CRS) is a common disorder characterized by mucosal inflammation of the nose and paranasal sinuses with sinonasal symptoms persisting for greater than 12 weeks. The etiology of CRS is incompletely understood. Current understanding supports inflammation, rather than...

Chronic kidney disease and associated cardiovascular risk factors in chinese with type 2 diabetes.

Diabetes & metabolism journal

Lou QL, Ouyang XJ, Gu LB, Mo YZ, Ma R, Nan J, Kong A, So WY, Ko G, Chan J, Chow CC, Bian RW.
PMID: 23275937
Diabetes Metab J. 2012 Dec;36(6):433-42. doi: 10.4093/dmj.2012.36.6.433. Epub 2012 Dec 12.

BACKGROUND: To determine the frequency of chronic kidney disease (CKD) and its associated risk factors in Chinese type 2 diabetic patients, we conducted a cross-sectional study in Nanjing, China, in the period between January 2008 and December 2009.METHODS: Patients...

Coefficients of inbreeding and homozygosity in recurrent selection: The case of m linked loci.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

Cain RL, Hinkelmann K.
PMID: 24430979
Theor Appl Genet. 1972 Jan;42(5):196-207. doi: 10.1007/BF00282507.

Methods of calculating the coefficients of inbreeding and homozygosity in a finite population undergoing recurrent selection (self-select-intercross in succeeding generations) are investigated for the case of m linked loci and effective directional selection. These coefficients are derived in terms...

Role of the aryl hydrocarbon receptor-interacting protein in familial isolated pituitary adenoma.

Expert review of endocrinology & metabolism

Cain JW, Miljic D, Popovic V, Korbonits M.
PMID: 30764022
Expert Rev Endocrinol Metab. 2010 Sep;5(5):681-695. doi: 10.1586/eem.10.42.

Pituitary adenomas are typically sporadic benign tumors. However, approximately 5% of cases have been found to be familial in origin. Of these, approximately 40% occur in the absence of multiple endocrine neoplasia type 1 or Carney complex and have...

Accelerated Hantzsch electrospray synthesis with temporal control of reaction intermediates.

Chemical science

Bain RM, Pulliam CJ, Cooks RG.
PMID: 28694938
Chem Sci. 2015 Jan 01;6(1):397-401. doi: 10.1039/c4sc02436b. Epub 2014 Sep 09.

Complex chemical reactions can occur in electrosprayed droplets on the millisecond time scale. The Hantzsch synthesis of 1,4-dihydropyridines was studied in this way using on-line mass spectral analysis to optimize conditions and characterize the product mixture. Changing the distance...

Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques.

Molecular therapy. Nucleic acids

Pardi N, LaBranche CC, Ferrari G, Cain DW, Tombácz I, Parks RJ, Muramatsu H, Mui BL, Tam YK, Karikó K, Polacino P, Barbosa CJ, Madden TD, Hope MJ, Haynes BF, Montefiori DC, Hu SL, Weissman D.
PMID: 30974332
Mol Ther Nucleic Acids. 2019 Apr 15;15:36-47. doi: 10.1016/j.omtn.2019.03.003. Epub 2019 Mar 21.

Despite the enormous effort in the development of effective vaccines against HIV-1, no vaccine candidate has elicited broadly neutralizing antibodies in humans. Thus, generation of more effective anti-HIV vaccines is critically needed. Here we characterize the immune responses induced...

A case for multiscale habitat selection studies of small mammals.

Journal of mammalogy

Schweiger BR, Frey JK, Cain JW.
PMID: 34650347
J Mammal. 2021 Jul 12;102(5):1249-1265. doi: 10.1093/jmammal/gyab071. eCollection 2021 Oct.

Habitat information for small mammals typically consists of anecdotal descriptions or infrequent analyses of habitat use, which often are reported erroneously as signifying habitat preference, requirements, or quality. Habitat preferences can be determined only by analysis of habitat selection,...

Showing 1 to 12 of 102 entries