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Showing 1 to 12 of 18 entries
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Relating SARS-CoV-2 shedding rate in wastewater to daily positive tests data: A consistent model based approach.

The Science of the total environment

Petala M, Kostoglou M, Karapantsios T, Dovas CI, Lytras T, Paraskevis D, Roilides E, Koutsolioutsou-Benaki A, Panagiotakopoulos G, Sypsa V, Metallidis S, Papa A, Stylianidis E, Papadopoulos A, Tsiodras S, Papaioannou N.
PMID: 34627900
Sci Total Environ. 2022 Feb 10;807:150838. doi: 10.1016/j.scitotenv.2021.150838. Epub 2021 Oct 08.

During the COVID-19 pandemic, wastewater-based epidemiology (WBE) has been engaged to complement medical surveillance and in some cases to also act as an early diagnosis indicator of viral spreading in the community. Most efforts worldwide by the scientific community...

Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids.

Molecular psychiatry

Pérez MJ, Ivanyuk D, Panagiotakopoulou V, Di Napoli G, Kalb S, Brunetti D, Al-Shaana R, Kaeser SA, Fraschka SA, Jucker M, Zeviani M, Viscomi C, Deleidi M.
PMID: 32632204
Mol Psychiatry. 2021 Oct;26(10):5733-5750. doi: 10.1038/s41380-020-0807-4. Epub 2020 Jul 07.

Mutations in pitrilysin metallopeptidase 1 (PITRM1), a mitochondrial protease involved in mitochondrial precursor processing and degradation, result in a slow-progressing syndrome characterized by cerebellar ataxia, psychotic episodes, and obsessive behavior, as well as cognitive decline. To investigate the pathogenetic...

Author Correction: A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration.

Nature communications

Corallino S, Malinverno C, Neumann B, Tischer C, Palamidessi A, Frittoli E, Panagiotakopoulou M, Disanza A, Malet-Engra G, Nastaly P, Galli C, Luise C, Bertalot G, Pece S, Di Fiore PP, Gauthier N, Ferrari A, Maiuri P, Scita G.
PMID: 29789562
Nat Commun. 2018 May 22;9(1):2085. doi: 10.1038/s41467-018-04515-y.

The originally published version of this Article contained an error in the name of the author Salvatore Corallino, which was incorrectly given as Corallino Salvatore. This has now been corrected in both the PDF and HTML versions of the...

Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids.

Molecular psychiatry

Pérez MJ, Ivanyuk D, Panagiotakopoulou V, Di Napoli G, Kalb S, Brunetti D, Al-Shaana R, Kaeser SA, Fraschka SA, Jucker M, Zeviani M, Viscomi C, Deleidi M.
PMID: 32632204
Mol Psychiatry. 2021 Oct;26(10):5733-5750. doi: 10.1038/s41380-020-0807-4. Epub 2020 Jul 07.

Mutations in pitrilysin metallopeptidase 1 (PITRM1), a mitochondrial protease involved in mitochondrial precursor processing and degradation, result in a slow-progressing syndrome characterized by cerebellar ataxia, psychotic episodes, and obsessive behavior, as well as cognitive decline. To investigate the pathogenetic...

Amidoxime prodrugs convert to potent cell-active multimodal inhibitors of the dengue virus protease.

European journal of medicinal chemistry

Swarbrick C, Zogali V, Chan KWK, Kiousis D, Gwee CP, Wang S, Lescar J, Luo D, von Itzstein M, Matsoukas MT, Panagiotakopoulos G, Vasudevan SG, Rassias G.
PMID: 34298282
Eur J Med Chem. 2021 Nov 15;224:113695. doi: 10.1016/j.ejmech.2021.113695. Epub 2021 Jul 10.

The flavivirus genus of the Flaviviridae family comprises Dengue, Zika and West-Nile viruses which constitute unmet medical needs as neither appropriate antivirals nor safe vaccines are available. The dengue NS2BNS3 protease is one of the most promising validated targets...

Cellular mechanisms underlying the effects of an early experience on cognitive abilities and affective states.

Annals of general psychiatry

Garoflos E, Panagiotaropoulos T, Pondiki S, Stamatakis A, Philippidis E, Stylianopoulou F.
PMID: 15876359
Ann Gen Psychiatry. 2005 Apr 06;4:8. doi: 10.1186/1744-859X-4-8. eCollection 2005.

In the present study we investigated the effects of neonatal handling, an animal model of early experience, on spatial learning and memory, on hippocampal glucocorticoid (GR), mineralocorticoid (MR) and type 1A serotonin (5-HT1A) receptors, as well as brain derived...

["Continuum" and "Spectrum" hypotheses of depressive disorders].

Psychiatrike = Psychiatriki

Panagiotakopoulou A, Kontaxaki MI.
PMID: 22466628
Psychiatriki. 2007 Jul;18(3):239-50.

Nowadays, the acceptance of depressive disorders as distinct entities in a categorical system with clearly defined diagnostic criteria has been considered by many researchers to be dysfunctional and stringent. An increasing number of patients with mild depressive symptomatology and...

Effects of an Early Experience Involving Training in a T-Maze Under either Denial or Receipt of Expected Reward through Maternal Contact.

Frontiers in endocrinology

Stamatakis A, Diamantopoulou A, Panagiotaropoulos T, Raftogianni A, Stylianopoulou F.
PMID: 24298269
Front Endocrinol (Lausanne). 2013 Nov 15;4:178. doi: 10.3389/fendo.2013.00178.

The mother is the most salient stimulus for the developing pups and a number of early experience models employ manipulation of the mother-infant interaction. We have developed a new model which in addition to changes in maternal behavior includes...

Relating SARS-CoV-2 shedding rate in wastewater to daily positive tests data: A consistent model based approach.

The Science of the total environment

Petala M, Kostoglou M, Karapantsios T, Dovas CI, Lytras T, Paraskevis D, Roilides E, Koutsolioutsou-Benaki A, Panagiotakopoulos G, Sypsa V, Metallidis S, Papa A, Stylianidis E, Papadopoulos A, Tsiodras S, Papaioannou N.
PMID: 34627900
Sci Total Environ. 2021 Oct 08;807:150838. doi: 10.1016/j.scitotenv.2021.150838. Epub 2021 Oct 08.

During the COVID-19 pandemic, wastewater-based epidemiology (WBE) has been engaged to complement medical surveillance and in some cases to also act as an early diagnosis indicator of viral spreading in the community. Most efforts worldwide by the scientific community...

["Continuum" and "Spectrum" hypotheses of depressive disorders].

Psychiatrike = Psychiatriki

Panagiotakopoulou A, Kontaxaki MI.
PMID: 22466628
Psychiatriki. 2007 Jul;18(3):239-50.

Nowadays, the acceptance of depressive disorders as distinct entities in a categorical system with clearly defined diagnostic criteria has been considered by many researchers to be dysfunctional and stringent. An increasing number of patients with mild depressive symptomatology and...

Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids.

Molecular psychiatry

Pérez MJ, Ivanyuk D, Panagiotakopoulou V, Di Napoli G, Kalb S, Brunetti D, Al-Shaana R, Kaeser SA, Fraschka SA, Jucker M, Zeviani M, Viscomi C, Deleidi M.
PMID: 32632204
Mol Psychiatry. 2020 Jul 07; doi: 10.1038/s41380-020-0807-4. Epub 2020 Jul 07.

Mutations in pitrilysin metallopeptidase 1 (PITRM1), a mitochondrial protease involved in mitochondrial precursor processing and degradation, result in a slow-progressing syndrome characterized by cerebellar ataxia, psychotic episodes, and obsessive behavior, as well as cognitive decline. To investigate the pathogenetic...

Relating SARS-CoV-2 shedding rate in wastewater to daily positive tests data: A consistent model based approach.

The Science of the total environment

Petala M, Kostoglou M, Karapantsios T, Dovas CI, Lytras T, Paraskevis D, Roilides E, Koutsolioutsou-Benaki A, Panagiotakopoulos G, Sypsa V, Metallidis S, Papa A, Stylianidis E, Papadopoulos A, Tsiodras S, Papaioannou N.
PMID: 34627900
Sci Total Environ. 2022 Feb 10;807:150838. doi: 10.1016/j.scitotenv.2021.150838. Epub 2021 Oct 08.

During the COVID-19 pandemic, wastewater-based epidemiology (WBE) has been engaged to complement medical surveillance and in some cases to also act as an early diagnosis indicator of viral spreading in the community. Most efforts worldwide by the scientific community...

Showing 1 to 12 of 18 entries