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Showing 1 to 12 of 174 entries
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International trends in treatment in training schools and institutions.

The American journal of orthopsychiatry

PAPANEK E.
PMID: 14894640
Am J Orthopsychiatry. 1952 Jan;22(1):118-26.

No abstract available.

Draft Genome Sequence of the Fast-Growing Bacterium Vibrio natriegens Strain DSMZ 759.

Genome announcements

Maida I, Bosi E, Perrin E, Papaleo MC, Orlandini V, Fondi M, Fani R, Wiegel J, Bianconi G, Canganella F.
PMID: 23969053
Genome Announc. 2013 Aug 22;1(4). doi: 10.1128/genomeA.00648-13.

Vibrio natriegens is a Gram-negative bacterium known for its extremely short doubling time. Here we present the annotated draft genome sequence of Vibrio natriegens strain DSMZ 759, with the aim of providing insights about its high growth rate.

Computational approaches to shed light on molecular mechanisms in biological processes.

Theoretical chemistry accounts

Moro G, Bonati L, Bruschi M, Cosentino U, De Gioia L, Fantucci PC, Pandini A, Papaleo E, Pitea D, Saracino GA, Zampella G.
PMID: 21415934
Theor Chem Acc. 2007 May 01;117(5):723-741. doi: 10.1007/s00214-006-0203-4.

Computational approaches based on Molecular Dynamics simulations, Quantum Mechanical methods and 3D Quantitative Structure-Activity Relationships were employed by computational chemistry groups at the University of Milano-Bicocca to study biological processes at the molecular level. The paper reports the methodologies...

Global time-size distribution of volcanic eruptions on Earth.

Scientific reports

Papale P.
PMID: 29717232
Sci Rep. 2018 May 01;8(1):6838. doi: 10.1038/s41598-018-25286-y.

Volcanic eruptions differ enormously in their size and impacts, ranging from quiet lava flow effusions along the volcano flanks to colossal events with the potential to affect our entire civilization. Knowledge of the time and size distribution of volcanic...

Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms.

Cancer cell

Kleppe M, Koche R, Zou L, van Galen P, Hill CE, Dong L, De Groote S, Papalexi E, Hanasoge Somasundara AV, Cordner K, Keller M, Farnoud N, Medina J, McGovern E, Reyes J, Roberts J, Witkin M, Rapaport F, Teruya-Feldstein J, Qi J, Rampal R, Bernstein BE, Bradner JE, Levine RL.
PMID: 29634952
Cancer Cell. 2018 Apr 09;33(4):785-787. doi: 10.1016/j.ccell.2018.03.024.

No abstract available.

Acute Administration of URB597 Fatty Acid Amide Hydrolase Inhibitor Prevents Attentional Impairments by Distractors in Adolescent Mice.

Frontiers in pharmacology

Contarini G, Ferretti V, Papaleo F.
PMID: 31379568
Front Pharmacol. 2019 Jul 19;10:787. doi: 10.3389/fphar.2019.00787. eCollection 2019.

The maturation of attentional control during adolescence might influence later functional outcome or predisposition to psychiatric disorders. During adolescence, the cannabinoid system is particularly sensitive to pharmacological challenges, with potential impact on cognitive functions. Here, we used a recently...

Clinical Interest of LMO2 Testing for the Diagnosis of Aggressive Large B-Cell Lymphomas.

Cancers

Vazquez I, Papaleo N, Garcia E, Salido M, Salar A, Hernandez S, Calvo X, Colomo L.
PMID: 32260556
Cancers (Basel). 2020 Apr 05;12(4). doi: 10.3390/cancers12040884.

MYC rearrangements usually confer aggressive biological behavior to large B-cell lymphomas. In this study, we aimed to evaluate the relevance of LMO2 detection to the clinical approach to these tumors. First, the ability of LMO2 loss of expression to...

Lower Airway Microbiota.

Frontiers in pediatrics

Pulvirenti G, Parisi GF, Giallongo A, Papale M, Manti S, Savasta S, Licari A, Marseglia GL, Leonardi S.
PMID: 31612122
Front Pediatr. 2019 Sep 27;7:393. doi: 10.3389/fped.2019.00393. eCollection 2019.

During the last several years, the interest in the role of microbiota in human health has grown significantly. For many years, the lung was considered a sterile environment, and only recently, with the use of more sophisticated techniques, has...

AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.

Nature

Maiani E, Milletti G, Nazio F, Holdgaard SG, Bartkova J, Rizza S, Cianfanelli V, Lorente M, Simoneschi D, Di Marco M, D'Acunzo P, Di Leo L, Rasmussen R, Montagna C, Raciti M, De Stefanis C, Gabicagogeascoa E, Rona G, Salvador N, Pupo E, Merchut-Maya JM, Daniel CJ, Carinci M, Cesarini V, O'sullivan A, Jeong YT, Bordi M, Russo F, Campello S, Gallo A, Filomeni G, Lanzetti L, Sears RC, Hamerlik P, Bartolazzi A, Hynds RE, Pearce DR, Swanton C, Pagano M, Velasco G, Papaleo E, De Zio D, Maya-Mendoza A, Locatelli F, Bartek J, Cecconi F.
PMID: 33854232
Nature. 2021 Apr;592(7856):799-803. doi: 10.1038/s41586-021-03422-5. Epub 2021 Apr 14.

Mammalian development, adult tissue homeostasis and the avoidance of severe diseases including cancer require a properly orchestrated cell cycle, as well as error-free genome maintenance. The key cell-fate decision to replicate the genome is controlled by two major signalling...

Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling.

Acta neuropathologica

Nazio F, Po A, Abballe L, Ballabio C, Diomedi Camassei F, Bordi M, Camera A, Caruso S, Caruana I, Pezzullo M, Ferraina C, Milletti G, Gianesello M, Reddel S, De Luca CD, Ceglie D, Marinelli S, Campello S, Papaleo E, Miele E, Cacchione A, Carai A, Vinci M, Velardi E, De Angelis B, Tiberi L, Quintarelli C, Mastronuzzi A, Ferretti E, Locatelli F, Cecconi F.
PMID: 34302498
Acta Neuropathol. 2021 Sep;142(3):537-564. doi: 10.1007/s00401-021-02347-7. Epub 2021 Jul 24.

Medulloblastoma (MB) is a childhood malignant brain tumour comprising four main subgroups characterized by different genetic alterations and rate of mortality. Among MB subgroups, patients with enhanced levels of the c-MYC oncogene (MB

Importance of anti-SARS-CoV-2 assay antigenic composition as revealed by the results of the Belgian external quality assessment (EQA) scheme.

Diagnostic microbiology and infectious disease

Moerman A, Vernelen K, China B, Capron A, Bossche DVD, Mariën J, Ariën KK, Van Acker J, Delforge ML, Reynders M, Boel A, Depypere M, Van Gasse N, Vijgen S, Brauner J, Dujardin B, Padalko E.
PMID: 34773801
Diagn Microbiol Infect Dis. 2022 Feb;102(2):115561. doi: 10.1016/j.diagmicrobio.2021.115561. Epub 2021 Oct 11.

We report on sample IS/17575 since it generated highly divergent results in the Belgian SARS-CoV-2 serology external quality assessment scheme. Sample IS/17575 was serum originating from a 30 years old male patient. 124 diagnostic laboratories analysed this sample. A...

Ubiquitin Interacting Motifs: Duality Between Structured and Disordered Motifs.

Frontiers in molecular biosciences

Lambrughi M, Maiani E, Aykac Fas B, Shaw GS, Kragelund BB, Lindorff-Larsen K, Teilum K, Invernizzi G, Papaleo E.
PMID: 34262938
Front Mol Biosci. 2021 Jun 28;8:676235. doi: 10.3389/fmolb.2021.676235. eCollection 2021.

Ubiquitin is a small protein at the heart of many cellular processes, and several different protein domains are known to recognize and bind ubiquitin. A common motif for interaction with ubiquitin is the Ubiquitin Interacting Motif (UIM), characterized by...

Showing 1 to 12 of 174 entries