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Harem-holding males do not rise to the challenge: androgens respond to social but not to seasonal challenges in wild geladas.

Royal Society open science

Pappano DJ, Beehner JC.
PMID: 26064526
R Soc Open Sci. 2014 Sep 24;1(1):140081. doi: 10.1098/rsos.140081. eCollection 2014 Sep.

The challenge hypothesis has been enormously successful in predicting interspecific androgen profiles for vertebrate males. Nevertheless, in the absence of another theoretical framework, many researchers 'retrofit' the challenge hypothesis, so that its predictions also apply to intraspecific androgen comparisons....

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Pappano DJ, Beehner JC. Harem-holding males do not rise to the challenge: androgens respond to social but not to seasonal challenges in wild geladas. R Soc Open Sci. 2014;1(1):140081doi: 10.1098/rsos.140081.
Pappano, D. J., & Beehner, J. C. (2014). Harem-holding males do not rise to the challenge: androgens respond to social but not to seasonal challenges in wild geladas. Royal Society open science, 1(1), 140081. https://doi.org/10.1098/rsos.140081
Pappano, David J, and Beehner, Jacinta C. "Harem-holding males do not rise to the challenge: androgens respond to social but not to seasonal challenges in wild geladas." Royal Society open science vol. 1,1 (2014): 140081. doi: https://doi.org/10.1098/rsos.140081
Pappano DJ, Beehner JC. Harem-holding males do not rise to the challenge: androgens respond to social but not to seasonal challenges in wild geladas. R Soc Open Sci. 2014 Sep 24;1(1):140081. doi: 10.1098/rsos.140081. eCollection 2014 Sep. PMID: 26064526; PMCID: PMC4448764.
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Complexant efficiency of 2'-hydroxy-4-R-chalcones for Aluminium (III) and substituent's effect.

Talanta

Debattista NB, Pappano NB.
PMID: 18966941
Talanta. 1997 Nov;44(11):1967-71. doi: 10.1016/s0039-9140(96)02123-6.

The complexant efficiency with aluminium of 2'-hydroxy-4-R-chalcones, which depends on the nature and positions of the substituent was studied by a spectrophotometric method. The apparent formation constant was determined. The quantitative analysis of the substituent's influence on the complexation...

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Debattista NB, Pappano NB. Complexant efficiency of 2'-hydroxy-4-R-chalcones for Aluminium (III) and substituent's effect. Talanta. 1997;44(11):1967-71doi: 10.1016/s0039-9140(96)02123-6.
Debattista, N. B., & Pappano, N. B. (1997). Complexant efficiency of 2'-hydroxy-4-R-chalcones for Aluminium (III) and substituent's effect. Talanta, 44(11), 1967-71. https://doi.org/10.1016/s0039-9140(96)02123-6
Debattista, N B, and Pappano, N B. "Complexant efficiency of 2'-hydroxy-4-R-chalcones for Aluminium (III) and substituent's effect." Talanta vol. 44,11 (1997): 1967-71. doi: https://doi.org/10.1016/s0039-9140(96)02123-6
Debattista NB, Pappano NB. Complexant efficiency of 2'-hydroxy-4-R-chalcones for Aluminium (III) and substituent's effect. Talanta. 1997 Nov;44(11):1967-71. doi: 10.1016/s0039-9140(96)02123-6. PMID: 18966941.
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Rapid and accurate determination of chlorpheniramine maleate, noscapine hydrochloride and guaiphenesin in binary mixtures by derivative spectrophotometry.

Talanta

Pappano NB, De Micalizzi YC, Debattista NB, Ferretti FH.
PMID: 18966784
Talanta. 1997 Apr;44(4):633-9. doi: 10.1016/s0039-9140(96)02083-8.

Rapid and accurate binary mixture resolution of chlorpheniramine maleate-noscapine hydrochloride and chlorpheniramine maleate-guaiphenesin, was performed. Derivative spectrophotometry, by the zero-crossing measurements, was used due to the drugs closely overlapping absorption spectra. Neither sample pretreatment nor separation were required. Linear...

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Pappano NB, De Micalizzi YC, Debattista NB, et al. Rapid and accurate determination of chlorpheniramine maleate, noscapine hydrochloride and guaiphenesin in binary mixtures by derivative spectrophotometry. Talanta. 1997;44(4):633-9doi: 10.1016/s0039-9140(96)02083-8.
Pappano, N. B., De Micalizzi, Y. C., Debattista, N. B., & Ferretti, F. H. (1997). Rapid and accurate determination of chlorpheniramine maleate, noscapine hydrochloride and guaiphenesin in binary mixtures by derivative spectrophotometry. Talanta, 44(4), 633-9. https://doi.org/10.1016/s0039-9140(96)02083-8
Pappano, N B, et al. "Rapid and accurate determination of chlorpheniramine maleate, noscapine hydrochloride and guaiphenesin in binary mixtures by derivative spectrophotometry." Talanta vol. 44,4 (1997): 633-9. doi: https://doi.org/10.1016/s0039-9140(96)02083-8
Pappano NB, De Micalizzi YC, Debattista NB, Ferretti FH. Rapid and accurate determination of chlorpheniramine maleate, noscapine hydrochloride and guaiphenesin in binary mixtures by derivative spectrophotometry. Talanta. 1997 Apr;44(4):633-9. doi: 10.1016/s0039-9140(96)02083-8. PMID: 18966784.
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New antimicrobial combinations: substituted chalcones- oxacillin against methicillin resistant Staphylococcus aureus.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]

Talia JM, Debattista NB, Pappano NB.
PMID: 24031657
Braz J Microbiol. 2011 Apr;42(2):470-5. doi: 10.1590/S1517-838220110002000010. Epub 2011 Jun 01.

Staphylococcus aureus, the most virulent Staphylococcus species, is also the prevalent pathogen isolated from hospitalized patients and the second most common from patients in outpatient settings. In general, bacteria have the genetic ability to transmit and acquire resistance to...

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Talia JM, Debattista NB, Pappano NB. New antimicrobial combinations: substituted chalcones- oxacillin against methicillin resistant Staphylococcus aureus. Braz J Microbiol. 2011;42(2):470-5doi: 10.1590/S1517-838220110002000010.
Talia, J. M., Debattista, N. B., & Pappano, N. B. (2011). New antimicrobial combinations: substituted chalcones- oxacillin against methicillin resistant Staphylococcus aureus. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 42(2), 470-5. https://doi.org/10.1590/S1517-838220110002000010
Talia, Juan Manuel, et al. "New antimicrobial combinations: substituted chalcones- oxacillin against methicillin resistant Staphylococcus aureus." Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] vol. 42,2 (2011): 470-5. doi: https://doi.org/10.1590/S1517-838220110002000010
Talia JM, Debattista NB, Pappano NB. New antimicrobial combinations: substituted chalcones- oxacillin against methicillin resistant Staphylococcus aureus. Braz J Microbiol. 2011 Apr;42(2):470-5. doi: 10.1590/S1517-838220110002000010. Epub 2011 Jun 01. PMID: 24031657; PMCID: PMC3769842.
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Erratum: The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex.

Nature chemical biology

He Y, Selvaraju S, Curtin ML, Jakob CG, Zhu H, Comess KM, Shaw B, The J, Lima-Fernandes E, Szewczyk MM, Cheng D, Klinge KL, Li HQ, Pliushchev M, Algire MA, Maag D, Guo J, Dietrich J, Panchal SC, Petros AM, Sweis RF, Torrent M, Bigelow LJ, Senisterra G, Li F, Kennedy S, Wu Q, Osterling DJ, Lindley DJ, Gao W, Galasinski S, Barsyte-Lovejoy D, Vedadi M, Buchanan FG, Arrowsmith CH, Chiang GG, Sun C, Pappano WN.
PMID: 28853738
Nat Chem Biol. 2017 Jul 18;13(8):922. doi: 10.1038/nchembio0817-922b.

No abstract available.

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He Y, Selvaraju S, Curtin ML, et al. Erratum: The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex. Nat Chem Biol. 2017;13(8):922doi: 10.1038/nchembio0817-922b.
He, Y., Selvaraju, S., Curtin, M. L., Jakob, C. G., Zhu, H., Comess, K. M., Shaw, B., The, J., Lima-Fernandes, E., Szewczyk, M. M., Cheng, D., Klinge, K. L., Li, H. Q., Pliushchev, M., Algire, M. A., Maag, D., Guo, J., Dietrich, J., Panchal, S. C., Petros, A. M., Sweis, R. F., Torrent, M., Bigelow, L. J., Senisterra, G., Li, F., Kennedy, S., Wu, Q., Osterling, D. J., Lindley, D. J., Gao, W., Galasinski, S., Barsyte-Lovejoy, D., Vedadi, M., Buchanan, F. G., Arrowsmith, C. H., Chiang, G. G., Sun, C., & Pappano, W. N. (2017). Erratum: The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex. Nature chemical biology, 13(8), 922. https://doi.org/10.1038/nchembio0817-922b
He, Yupeng, et al. "Erratum: The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex." Nature chemical biology vol. 13,8 (2017): 922. doi: https://doi.org/10.1038/nchembio0817-922b
He Y, Selvaraju S, Curtin ML, Jakob CG, Zhu H, Comess KM, Shaw B, The J, Lima-Fernandes E, Szewczyk MM, Cheng D, Klinge KL, Li HQ, Pliushchev M, Algire MA, Maag D, Guo J, Dietrich J, Panchal SC, Petros AM, Sweis RF, Torrent M, Bigelow LJ, Senisterra G, Li F, Kennedy S, Wu Q, Osterling DJ, Lindley DJ, Gao W, Galasinski S, Barsyte-Lovejoy D, Vedadi M, Buchanan FG, Arrowsmith CH, Chiang GG, Sun C, Pappano WN. Erratum: The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex. Nat Chem Biol. 2017 Jul 18;13(8):922. doi: 10.1038/nchembio0817-922b. PMID: 28853738.
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Dual effects of entomopathogenic fungi on control of the pest Lobesia botrana and the pathogenic fungus Eutypella microtheca on grapevine.

Biological research

Aguilera-Sammaritano J, Caballero J, Deymié M, Rosa M, Vazquez F, Pappano D, Lechner B, González-Teuber M.
PMID: 34952648
Biol Res. 2021 Dec 24;54(1):44. doi: 10.1186/s40659-021-00367-x.

BACKGROUND: Entomopathogenic fungi (EPF) are the natural enemies of insect pests. Nevertheless, research on the use of EPF for simultaneous prevention of pest and disease agents on the same crop is limited. In this study, we explored the potential...

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Aguilera-Sammaritano J, Caballero J, Deymié M, et al. Dual effects of entomopathogenic fungi on control of the pest Lobesia botrana and the pathogenic fungus Eutypella microtheca on grapevine. Biol Res. 2021;54(1):44doi: 10.1186/s40659-021-00367-x.
Aguilera-Sammaritano, J., Caballero, J., Deymié, M., Rosa, M., Vazquez, F., Pappano, D., Lechner, B., & González-Teuber, M. (2021). Dual effects of entomopathogenic fungi on control of the pest Lobesia botrana and the pathogenic fungus Eutypella microtheca on grapevine. Biological research, 54(1), 44. https://doi.org/10.1186/s40659-021-00367-x
Aguilera-Sammaritano, Juan, et al. "Dual effects of entomopathogenic fungi on control of the pest Lobesia botrana and the pathogenic fungus Eutypella microtheca on grapevine." Biological research vol. 54,1 (2021): 44. doi: https://doi.org/10.1186/s40659-021-00367-x
Aguilera-Sammaritano J, Caballero J, Deymié M, Rosa M, Vazquez F, Pappano D, Lechner B, González-Teuber M. Dual effects of entomopathogenic fungi on control of the pest Lobesia botrana and the pathogenic fungus Eutypella microtheca on grapevine. Biol Res. 2021 Dec 24;54(1):44. doi: 10.1186/s40659-021-00367-x. PMID: 34952648.
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Discovery and development of potent and selective inhibitors of histone methyltransferase g9a.

ACS medicinal chemistry letters

Sweis RF, Pliushchev M, Brown PJ, Guo J, Li F, Maag D, Petros AM, Soni NB, Tse C, Vedadi M, Michaelides MR, Chiang GG, Pappano WN.
PMID: 24900801
ACS Med Chem Lett. 2014 Jan 02;5(2):205-9. doi: 10.1021/ml400496h. eCollection 2014 Feb 13.

G9a is a histone lysine methyltransferase responsible for the methylation of histone H3 lysine 9. The discovery of A-366 arose from a unique diversity screening hit, which was optimized by incorporation of a propyl-pyrrolidine subunit to occupy the enzyme...

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Sweis RF, Pliushchev M, Brown PJ, et al. Discovery and development of potent and selective inhibitors of histone methyltransferase g9a. ACS Med Chem Lett. 2014;5(2):205-9doi: 10.1021/ml400496h.
Sweis, R. F., Pliushchev, M., Brown, P. J., Guo, J., Li, F., Maag, D., Petros, A. M., Soni, N. B., Tse, C., Vedadi, M., Michaelides, M. R., Chiang, G. G., & Pappano, W. N. (2014). Discovery and development of potent and selective inhibitors of histone methyltransferase g9a. ACS medicinal chemistry letters, 5(2), 205-9. https://doi.org/10.1021/ml400496h
Sweis, Ramzi F, et al. "Discovery and development of potent and selective inhibitors of histone methyltransferase g9a." ACS medicinal chemistry letters vol. 5,2 (2014): 205-9. doi: https://doi.org/10.1021/ml400496h
Sweis RF, Pliushchev M, Brown PJ, Guo J, Li F, Maag D, Petros AM, Soni NB, Tse C, Vedadi M, Michaelides MR, Chiang GG, Pappano WN. Discovery and development of potent and selective inhibitors of histone methyltransferase g9a. ACS Med Chem Lett. 2014 Jan 02;5(2):205-9. doi: 10.1021/ml400496h. eCollection 2014 Feb 13. PMID: 24900801; PMCID: PMC4027767.
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Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8.

ACS medicinal chemistry letters

Judge RA, Zhu H, Upadhyay AK, Bodelle PM, Hutchins CW, Torrent M, Marin VL, Yu W, Vedadi M, Li F, Brown PJ, Pappano WN, Sun C, Petros AM.
PMID: 27994746
ACS Med Chem Lett. 2016 Oct 11;7(12):1102-1106. doi: 10.1021/acsmedchemlett.6b00303. eCollection 2016 Dec 08.

SETD8 is a histone H4-K20 methyltransferase that plays an essential role in the maintenance of genomic integrity during mitosis and in DNA damage repair, making it an intriguing target for cancer research. While some small molecule inhibitors for SETD8...

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Judge RA, Zhu H, Upadhyay AK, et al. Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8. ACS Med Chem Lett. 2016;7(12):1102-1106doi: 10.1021/acsmedchemlett.6b00303.
Judge, R. A., Zhu, H., Upadhyay, A. K., Bodelle, P. M., Hutchins, C. W., Torrent, M., Marin, V. L., Yu, W., Vedadi, M., Li, F., Brown, P. J., Pappano, W. N., Sun, C., & Petros, A. M. (2016). Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8. ACS medicinal chemistry letters, 7(12), 1102-1106. https://doi.org/10.1021/acsmedchemlett.6b00303
Judge, Russell A, et al. "Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8." ACS medicinal chemistry letters vol. 7,12 (2016): 1102-1106. doi: https://doi.org/10.1021/acsmedchemlett.6b00303
Judge RA, Zhu H, Upadhyay AK, Bodelle PM, Hutchins CW, Torrent M, Marin VL, Yu W, Vedadi M, Li F, Brown PJ, Pappano WN, Sun C, Petros AM. Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8. ACS Med Chem Lett. 2016 Oct 11;7(12):1102-1106. doi: 10.1021/acsmedchemlett.6b00303. eCollection 2016 Dec 08. PMID: 27994746; PMCID: PMC5150682.
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Feasibility and Acceptability of a Collaborative Lung Cancer Screening Educational Intervention Tailored for Individuals With Serious Mental Illness.

Journal of the American College of Radiology : JACR

Flores EJ, Neil JM, Tiersma KM, Pappano CR, Mulligan C, Van Alphen MU, Park ER, Irwin KE.
PMID: 34375628
J Am Coll Radiol. 2021 Dec;18(12):1624-1634. doi: 10.1016/j.jacr.2021.07.010. Epub 2021 Aug 07.

PURPOSE: Individuals with serious mental illness (SMI) experience disparities in lung cancer mortality. Using a two-phase, mixed-methods approach, we developed a person-centered lung cancer screening (LCS) educational intervention (phase 1) for individuals with SMI (schizophrenia and bipolar disorder) and...

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Flores EJ, Neil JM, Tiersma KM, et al. Feasibility and Acceptability of a Collaborative Lung Cancer Screening Educational Intervention Tailored for Individuals With Serious Mental Illness. J Am Coll Radiol. 2021;18(12):1624-1634doi: 10.1016/j.jacr.2021.07.010.
Flores, E. J., Neil, J. M., Tiersma, K. M., Pappano, C. R., Mulligan, C., Van Alphen, M. U., Park, E. R., & Irwin, K. E. (2021). Feasibility and Acceptability of a Collaborative Lung Cancer Screening Educational Intervention Tailored for Individuals With Serious Mental Illness. Journal of the American College of Radiology : JACR, 18(12), 1624-1634. https://doi.org/10.1016/j.jacr.2021.07.010
Flores, Efrén J, et al. "Feasibility and Acceptability of a Collaborative Lung Cancer Screening Educational Intervention Tailored for Individuals With Serious Mental Illness." Journal of the American College of Radiology : JACR vol. 18,12 (2021): 1624-1634. doi: https://doi.org/10.1016/j.jacr.2021.07.010
Flores EJ, Neil JM, Tiersma KM, Pappano CR, Mulligan C, Van Alphen MU, Park ER, Irwin KE. Feasibility and Acceptability of a Collaborative Lung Cancer Screening Educational Intervention Tailored for Individuals With Serious Mental Illness. J Am Coll Radiol. 2021 Dec;18(12):1624-1634. doi: 10.1016/j.jacr.2021.07.010. Epub 2021 Aug 07. PMID: 34375628.
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Improving Emergency Room Utilization During the COVID-19 Pandemic: A Telemedicine Social Determinants of Health Outreach Approach.

Journal of community hospital internal medicine perspectives

Austin S, Pappan N, Venkat D.
PMID: 34211654
J Community Hosp Intern Med Perspect. 2021 Jun 21;11(4):485-488. doi: 10.1080/20009666.2021.1936950.

High-risk patients over the age of 65, who had chronic medical conditions, and had not yet had a primary care visit within 2020 were identified. A subgroup of patients participated in a survey to assess social determinants of health...

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Austin S, Pappan N, Venkat D. Improving Emergency Room Utilization During the COVID-19 Pandemic: A Telemedicine Social Determinants of Health Outreach Approach. J Community Hosp Intern Med Perspect. 2021;11(4):485-488doi: 10.1080/20009666.2021.1936950.
Austin, S., Pappan, N., & Venkat, D. (2021). Improving Emergency Room Utilization During the COVID-19 Pandemic: A Telemedicine Social Determinants of Health Outreach Approach. Journal of community hospital internal medicine perspectives, 11(4), 485-488. https://doi.org/10.1080/20009666.2021.1936950
Austin, Scarlett, et al. "Improving Emergency Room Utilization During the COVID-19 Pandemic: A Telemedicine Social Determinants of Health Outreach Approach." Journal of community hospital internal medicine perspectives vol. 11,4 (2021): 485-488. doi: https://doi.org/10.1080/20009666.2021.1936950
Austin S, Pappan N, Venkat D. Improving Emergency Room Utilization During the COVID-19 Pandemic: A Telemedicine Social Determinants of Health Outreach Approach. J Community Hosp Intern Med Perspect. 2021 Jun 21;11(4):485-488. doi: 10.1080/20009666.2021.1936950. PMID: 34211654; PMCID: PMC8221136.
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Taking the time to get it bright: Use of ultrasound enhancing agent redirects clinical course of an unstable patient.

Journal of cardiology cases

Pappan N, Kyvernitakis A, Kashyap K, Grove E, Alpert CM, Biederman RWW, Hughes-Doichev RA.
PMID: 33437339
J Cardiol Cases. 2020 Sep 29;23(1):38-40. doi: 10.1016/j.jccase.2020.09.001. eCollection 2021 Jan.

The use of ultrasound enhancing agents (UEA) during echocardiography helps to optimize visualization in technically difficult studies, with improved left ventricular opacification and endocardial border definition. The use of these agents may often unveil critical data that drastically alter...

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Pappan N, Kyvernitakis A, Kashyap K, et al. Taking the time to get it bright: Use of ultrasound enhancing agent redirects clinical course of an unstable patient. J Cardiol Cases. 2020;23(1):38-40doi: 10.1016/j.jccase.2020.09.001.
Pappan, N., Kyvernitakis, A., Kashyap, K., Grove, E., Alpert, C. M., Biederman, R. W. W., & Hughes-Doichev, R. A. (2021). Taking the time to get it bright: Use of ultrasound enhancing agent redirects clinical course of an unstable patient. Journal of cardiology cases, 23(1), 38-40. https://doi.org/10.1016/j.jccase.2020.09.001
Pappan, Nikos, et al. "Taking the time to get it bright: Use of ultrasound enhancing agent redirects clinical course of an unstable patient." Journal of cardiology cases vol. 23,1 (2021): 38-40. doi: https://doi.org/10.1016/j.jccase.2020.09.001
Pappan N, Kyvernitakis A, Kashyap K, Grove E, Alpert CM, Biederman RWW, Hughes-Doichev RA. Taking the time to get it bright: Use of ultrasound enhancing agent redirects clinical course of an unstable patient. J Cardiol Cases. 2020 Sep 29;23(1):38-40. doi: 10.1016/j.jccase.2020.09.001. eCollection 2021 Jan. PMID: 33437339; PMCID: PMC7783554.
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Identifying Social Determinants of Health Leads to the Diagnoses of Scurvy in the Developed World. Case Report.

SN comprehensive clinical medicine

Pappan N, Sarma D, Rabe T, Petroccione R.
PMID: 33681707
SN Compr Clin Med. 2021 Feb 27;1-3. doi: 10.1007/s42399-021-00834-2. Epub 2021 Feb 27.

Identifying social determinants of health can help diagnose certain nutritional deficiencies. By overcoming these barriers, we can prevent future hospitalizations and better public health. We present a unique case where a 46-year-old man presents with bilateral lower extremity swelling...

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Pappan N, Sarma D, Rabe T, et al. Identifying Social Determinants of Health Leads to the Diagnoses of Scurvy in the Developed World. Case Report. SN Compr Clin Med. 2021;1-3doi: 10.1007/s42399-021-00834-2.
Pappan, N., Sarma, D., Rabe, T., & Petroccione, R. (2021). Identifying Social Determinants of Health Leads to the Diagnoses of Scurvy in the Developed World. Case Report. SN comprehensive clinical medicine, 1-3. https://doi.org/10.1007/s42399-021-00834-2
Pappan, Nikos, et al. "Identifying Social Determinants of Health Leads to the Diagnoses of Scurvy in the Developed World. Case Report." SN comprehensive clinical medicine vol. (2021): 1-3. doi: https://doi.org/10.1007/s42399-021-00834-2
Pappan N, Sarma D, Rabe T, Petroccione R. Identifying Social Determinants of Health Leads to the Diagnoses of Scurvy in the Developed World. Case Report. SN Compr Clin Med. 2021 Feb 27;1-3. doi: 10.1007/s42399-021-00834-2. Epub 2021 Feb 27. PMID: 33681707; PMCID: PMC7910790.
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