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Showing 1 to 12 of 202 entries
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Explaining forest productivity using tree functional traits and phylogenetic information: two sides of the same coin over evolutionary scale?.

Ecology and evolution

Paquette A, Joly S, Messier C.
PMID: 26140194
Ecol Evol. 2015 May;5(9):1774-83. doi: 10.1002/ece3.1456. Epub 2015 Mar 27.

Given evidences that diverse ecosystems provide more services than depauperate ones, much attention has now turned toward finding meaningful and operational diversity indices. We ask two questions: (1) Does phylogenetic diversity contain additional information not explained by functional traits?...

Cognitive evolution in natalizumab-treated multiple sclerosis patients.

Multiple sclerosis journal - experimental, translational and clinical

Jacques FH, Harel BT, Schembri AJ, Paquette C, Bilodeau B, Kalinowski P, Roy R.
PMID: 28607732
Mult Scler J Exp Transl Clin. 2016 Jun 07;2:2055217316657116. doi: 10.1177/2055217316657116. eCollection 2016.

BACKGROUND: Cognitive dysfunction affects up to 65% of multiple sclerosis (MS) patients and progresses over time. Natalizumab has been shown to be superior to placebo in preserving cognition for the first two years of therapy.OBJECTIVES: The objectives of this...

trans,anti,trans-Tetra(spirotetrahydrofuranyl)cyclohexane-1,2-dione. Stereocontrolled Synthesis and Definition of Its Susceptibility to Photoisomerization.

The Journal of organic chemistry

Paquette LA, Lowinger TB, Bolin DG, Branan BM.
PMID: 11667679
J Org Chem. 1996 Oct 18;61(21):7486-7491. doi: 10.1021/jo960961p.

The title alpha-diketone (18) has been synthesized in stereocontrolled fashion. The ability to introduce the four contiguous spirocyclic ether oxygens in extended trans fashion rests on the ability of the Normant reagent (ClMgCH(2)CH(2)CH(2)OMgCl) to engage in chelation control during...

Selected topics related to occupational exposures. Part II. Occupational infectious diseases.

Disease-a-month : DM

Leikin JB, Davis A, Klodd DA, Thunder T, Kelafant GA, Paquette DL, Rothe MJ, Rubin R.
PMID: 10830611
Dis Mon. 2000 Apr;46(4):256-75. doi: 10.1016/s0011-5029(00)90034-8.

No abstract available.

Selected topics related to occupational exposures. Part V. Occupational cardiovascular disease.

Disease-a-month : DM

Leikin JB, Davis A, Klodd DA, Thunder T, Kelafant GA, Paquette DL, Rothe MJ, Rubin R.
PMID: 10830614
Dis Mon. 2000 Apr;46(4):311-22. doi: 10.1016/s0011-5029(00)90037-3.

Cardiovascular disease is common in the United States. Several occupational exposures, such as carbon disulfide and organic nitrates, are believed to cause occupational cardiovascular disease. In addition some other agents, such as lead and cadmium, may indirectly cause cardiovascular...

An Enantioselective Ring Expansion Route Leading to Furanose and Pyranose Nucleosides Featuring Spirodiketopiperazines at the Anomeric Position.

The Journal of organic chemistry

Paquette LA, Brand S, Behrens C.
PMID: 11674296
J Org Chem. 1999 Mar 19;64(6):2010-2025. doi: 10.1021/jo982259u.

A study directed at the enantioselective synthesis of spirodiketopiperazine homologues of hydantocidin is described. Furanoid glycals, systems that are amenable to C-5 metalation in the presence of tert-butyllithium, are readily coupled to N-protected 2,3-azetidinediones provided that at least 1...

Utilization of the Phenylthio Substituent as a Multipurpose Synthetic Tool. Direct Application to the Enantioselective Construction of (-)-Salsolene Oxide.

The Journal of organic chemistry

Paquette LA, Sun LQ, Watson TJ, Friedrich D, Freeman BT.
PMID: 11671925
J Org Chem. 1997 Nov 14;62(23):8155-8161. doi: 10.1021/jo971244d.

The architecturally unprecedented sesquiterpene (-)-salsolene oxide (1) has been synthesized in enantioselective fashion from (R)-(-)-carvone. Generation of the phenylthio-substituted vinyl ketene 4 is followed by intramolecular cyclization to the functionalized cyclobutanone 9. Vinyllithium addition to this intermediate proceeds in...

Lithium ion-selective binding properties of a conformationally constrained tris(spirotetrahydrofuran) secured to an inositol orthoformate platform.

Organic letters

Tae J, Rogers RD, Paquette LA.
PMID: 10814266
Org Lett. 2000 Jan 27;2(2):139-42. doi: 10.1021/ol990342d.

[structure: see text] The C3V-symmetric triaxially locked trispirotetrahydrofuran 2 binds Li+ ions strongly and Na+ ions much less effectively. The observed discrimination factor is attributed to greater structural preorganiztion and lower solvation prior to selective complexation, and particularly to...

A convenient method for removing all highly-colored byproducts generated during olefin metathesis reactions.

Organic letters

Paquette LA, Schloss JD, Efremov I, Fabris F, Gallou F, Mendez-Andino J, Yang J.
PMID: 10810722
Org Lett. 2000 May 04;2(9):1259-61. doi: 10.1021/ol000036w.

[formula: see text] Addition of a very modest amount of lead tetraacetate (1.50 equiv relative to the amount of Grubbs catalyst) to ring-closing metathesis reaction mixtures effectively removes all colored ruthenium and phosphine impurities to deliver colories reaction products.

ansa-[(tert-Butylamino)(isodicyclopentadienyl)dimethylsilane]Zr(NMe2)2 prepared by an amine-elimination reaction.

Acta crystallographica. Section C, Crystal structure communications

Gallucci JC, Gentil S, Pirio N, Meunier P, Gallou F, Paquette LA.
PMID: 12682383
Acta Crystallogr C. 2003 Apr;59:M109-11. doi: 10.1107/s0108270103003172. Epub 2003 Mar 11.

An amine-elimination reaction was used to obtain the title compound, i.e. (N-tert-butyl-N-[[(1,2,3,3a,7a-eta)-4,5,6,7-tetrahydro-4,7-methano-1H-inden-2-yl]dimethylsilyl]amido-kappaN)bis(N-methylmethanaminato-kappaN)zirconium(IV) or [isodiCpSiMe(2)N-tert-butyl]Zr(NMe(2))(2) (Cp is cyclopentadienyl), [Zr(C(16)H(25)NSi)(C(2)H(6)N)(2)], in very good yield. Treatment of isodiCpHSiMe(2)NH-tert-butyl with Zr(NMe(2))(4) leads to the formation of a yellow solid that can be purified...

Contrasting diastereofacial selectivity associated with N-phenyltriazolinedione cycloadditions to oxaspirocycloheptatrienes.

Organic letters

Paquette LA, Webber P, Simpson I.
PMID: 12529134
Org Lett. 2003 Jan 23;5(2):177-80. doi: 10.1021/ol020223p.

[reaction: see text] The cycloaddition of N-phenyltriazolinedione to a pair of spirocyclic cycloheptatrienes featuring a tetrahydrofuran or tetrahydropyran ring is shown to proceed with opposite pi-facial stereoselectivity. In addition, the furan undergoes direct [4+2] cycloaddition to the cycloheptatriene whereas...

Dinuclear cobalt bis(dioxolene) complex exhibiting two sequential thermally induced valence tautomeric transitions.

Inorganic chemistry

Hearns NG, Korcok JL, Paquette MM, Preuss KE.
PMID: 17054329
Inorg Chem. 2006 Oct 30;45(22):8817-9. doi: 10.1021/ic0608997.

4,6-Di-2'-pyridylpyrimidine is employed as a bis(diimine) ligand bridging two cobalt bis(dioxolene) centers. The thermally induced valence tautomeric transitions of these two metal centers are coupled through the ligand. The result is that sequential switching from high-spin Co(II) to low-spin...

Showing 1 to 12 of 202 entries