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Showing 1 to 12 of 84 entries
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Using Genetic Algorithms in a Large Nationally Representative American Sample to Abbreviate the Multidimensional Experiential Avoidance Questionnaire.

Frontiers in psychology

Sahdra BK, Ciarrochi J, Parker P, Scrucca L.
PMID: 26941672
Front Psychol. 2016 Feb 24;7:189. doi: 10.3389/fpsyg.2016.00189. eCollection 2016.

Genetic algorithms (GAs) are robust machine learning approaches for abbreviating a large set of variables into a shorter subset that maximally captures the variance in the original data. We employed a GA-based method to shorten the 62-item Multidimensional Experiential...

A Radical Approach to Asymmetric Aldol Synthesis.

The Journal of organic chemistry

Garner P, Leslie R, Anderson JT.
PMID: 11667557
J Org Chem. 1996 Oct 04;61(20):6754-6755. doi: 10.1021/jo961499b.

No abstract available.

S-(1-Oxido-2-pyridinyl)-1,1,3,3-tetramethylthiouronium Hexafluorophosphate. A New Reagent for Preparing Hindered Barton Esters.

The Journal of organic chemistry

Garner P, Anderson JT, Dey S, Youngs WJ, Galat K.
PMID: 11672163
J Org Chem. 1998 Aug 21;63(17):5732-5733. doi: 10.1021/jo980870n.

No abstract available.

Use of Silicon-Based Tethers to Control Diastereofacial Selectivity in Azomethine Ylide Cycloadditions(1).

The Journal of organic chemistry

Garner P, Cox PB, Anderson JT, Protasiewicz J, Zaniewski R.
PMID: 11671439
J Org Chem. 1997 Feb 07;62(3):493-498. doi: 10.1021/jo9609034.

A novel approach to controlling the diastereofacial selectivity of intramolecular dipolar cycloadditions of azomethine ylides (cf. 9 --> 8) by varying the structure a silicon-based tether is described. A correlation is found between the length of the tether dipolarophile...

A novel simulation model for the motor unit innervation process.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference

Jiang N, Englehart K, Parker P.
PMID: 17282872
Conf Proc IEEE Eng Med Biol Soc. 2005;2005:2993-6. doi: 10.1109/IEMBS.2005.1617103.

A simulation model for the Motor Unit Innervation Process (MUIP) is proposed. The model is based on the Hodgkin-Huxley (HH) model, which enables it to simulate the complex dynamics of MUIPs, such as the interactions between motor unit common...

Synthesis of highly functionalized pyrrolidines via a mild one-pot, three-component 1,3-dipolar cycloaddition process.

The Journal of organic chemistry

Garner P, Kaniskan HU.
PMID: 16356011
J Org Chem. 2005 Dec 23;70(26):10868-71. doi: 10.1021/jo051926y.

[reaction: see text] A simple and efficient one-pot, three-component synthesis of highly functionalized pyrrolidines via cascade imine --> azomethine ylide --> 1,3-dipolar cycloadditions is reported. Admixing a variety of aldehydes, dimethyl 2-aminomalonate, and electron deficient alkenes in THF leads...

Correlation between adherence rates measured by MEMS and self-reported questionnaires: a meta-analysis.

Health and quality of life outcomes

Shi L, Liu J, Fonseca V, Walker P, Kalsekar A, Pawaskar M.
PMID: 20836888
Health Qual Life Outcomes. 2010 Sep 13;8:99. doi: 10.1186/1477-7525-8-99.

PURPOSE: It is vital to understand the associations between the medication event monitoring systems (MEMS) and self-reported questionnaires (SRQs) because both are often used to measure medication adherence and can produce different results. In addition, the economic implication of...

SIMSUG 2011, Lancaster Environment Centre, 23-24 November, 2011.

Rapid communications in mass spectrometry : RCM

Barker P.
PMID: 22976202
Rapid Commun Mass Spectrom. 2012 Oct 30;26(20):2377. doi: 10.1002/rcm.6357.

No abstract available.

Validating the Copenhagen Psychosocial Questionnaire (COPSOQ-II) Using Set-ESEM: Identifying Psychosocial Risk Factors in a Sample of School Principals.

Frontiers in psychology

Dicke T, Marsh HW, Riley P, Parker PD, Guo J, Horwood M.
PMID: 29760670
Front Psychol. 2018 Apr 30;9:584. doi: 10.3389/fpsyg.2018.00584. eCollection 2018.

School principals world-wide report high levels of strain and attrition resulting in a shortage of qualified principals. It is thus crucial to identify psychosocial risk factors that reflect principals' occupational wellbeing. For this purpose, we used the Copenhagen Psychosocial...

Assessing tumor molecular profiling to guide treatments for patients with advanced female genital tract malignancy.

Oncotarget

Carter P, Alifrangis C, Cereser B, Chandrasinghe P, Del Bel Belluz L, Fotopoulou C, Frilling A, Herzog T, Moderau N, Tabassum N, Krell J, Stebbing J.
PMID: 29464050
Oncotarget. 2017 Dec 27;9(5):6007-6014. doi: 10.18632/oncotarget.23675. eCollection 2018 Jan 19.

Tumor molecular profiling has enabled selection of targeted therapies in a host of solid tumors. Here we used a retrospective clinical cohort, to evaluate the benefit of tailoring treatments for female genital tract malignancy, using tumor molecular profiles. Clinical...

How healthcare professionals can support older LGBTQ+ people living with dementia.

Nursing older people

Harper P.
PMID: 31468853
Nurs Older People. 2019 Sep 27;31(5):16-21. doi: 10.7748/nop.2019.e1115. Epub 2019 Jun 26.

Older lesbian, gay, bisexual, trans, queer and others (LGBTQ+) people living with dementia have specific needs related to their sexual orientation and identity that should be addressed to maintain their personhood. They may face challenges in health and social...

Design and Synthesis of Pyrrolidine-based Fragments That Sample Three-dimensional Molecular Space.

ACS medicinal chemistry letters

Garner P, Cox PB, Rathnayake U, Holloran N, Erdman P.
PMID: 31098004
ACS Med Chem Lett. 2019 Apr 12;10(5):811-815. doi: 10.1021/acsmedchemlett.9b00070. eCollection 2019 May 09.

Fragment-based drug discovery (FBDD) is a well-established technology for lead compound generation in drug discovery. As this technology has evolved, the design of fragments for screening has also evolved to engender not just an understanding of the role of...

Showing 1 to 12 of 84 entries