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Showing 1 to 12 of 14 entries
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Combination of inflammatory and amlodipine induced gingival overgrowth in a patient with cardiovascular disease.

Avicenna journal of medicine

Pasupuleti MK, Musalaiah SV, Nagasree M, Kumar PA.
PMID: 24251234
Avicenna J Med. 2013 Jul;3(3):68-72. doi: 10.4103/2231-0770.118462.

Gingival overgrowth (GO) is among one of the most important clinical features of gingival pathology frequently seen in periodontal clinic. Amlodipine is a comparatively new calcium channel blocker and is being used with increasing frequency in the management of...

Advanced-Glycation End-Products Induce Podocyte Injury and Contribute to Proteinuria.

Frontiers in medicine

Nishad R, Tahaseen V, Kavvuri R, Motrapu M, Singh AK, Peddi K, Pasupulati AK.
PMID: 34277660
Front Med (Lausanne). 2021 Jul 01;8:685447. doi: 10.3389/fmed.2021.685447. eCollection 2021.

The prevalence of diabetes reaches epidemic proportions. Diabetes is the leading cause of end-stage kidney disease (ESKD) since 30-40% of diabetic patients develop diabetic nephropathy. Albuminuria and glomerular filtration rate used to assess kidney function are considered surrogate outcomes...

Structural features and oligomeric nature of human podocin domain.

Biochemistry and biophysics reports

Mulukala SKN, Irukuvajjula SS, Kumar K, Garai K, Venkatesu P, Vadrevu R, Pasupulati AK.
PMID: 32617419
Biochem Biophys Rep. 2020 Jun 25;23:100774. doi: 10.1016/j.bbrep.2020.100774. eCollection 2020 Sep.

Podocytes are crucial cells of the glomerular filtration unit and plays a vital role at the interface of the blood-urine barrier. Podocyte slit-diaphragm is a modified tight junction that facilitates size and charge-dependent permselectivity. Several proteins including podocin, nephrin,...

Novel Actions of Growth Hormone in Podocytes: Implications for Diabetic Nephropathy.

Frontiers in medicine

Mukhi D, Nishad R, Menon RK, Pasupulati AK.
PMID: 28748185
Front Med (Lausanne). 2017 Jul 12;4:102. doi: 10.3389/fmed.2017.00102. eCollection 2017.

The kidney regulates water, electrolyte, and acid-base balance and thus maintains body homeostasis. The kidney's potential to ensure ultrafiltered and almost protein-free urine is compromised in various metabolic and hormonal disorders such as diabetes mellitus (DM). Diabetic nephropathy (DN)...

Stabilization of hypoxia-inducible factor 1α by cobalt chloride impairs podocyte morphology and slit-diaphragm function.

Journal of cellular biochemistry

Nakuluri K, Mukhi D, Mungamuri SK, Pasupulati AK.
PMID: 30387200
J Cell Biochem. 2018 Nov 01; doi: 10.1002/jcb.28041. Epub 2018 Nov 01.

Glomerular podocytes are the major components of the renal filtration barrier, and altered podocyte permselectivity is a key event in the pathogenesis of proteinuric conditions. Clinical conditions such as ischemia and sleep apnea and extreme physiological conditions such as...

Virtual reality-based 3-dimensional localization of stereotactic EEG (SEEG) depth electrodes and related brain anatomy in pediatric epilepsy surgery.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Phan TN, Prakash KJ, Elliott RS, Pasupuleti A, Gaillard WD, Keating RF, Oluigbo CO.
PMID: 34718866
Childs Nerv Syst. 2021 Oct 30; doi: 10.1007/s00381-021-05403-5. Epub 2021 Oct 30.

INTRODUCTION: The increasing use of stereoelectroencephalography (SEEG) in the USA and the need for three-dimensional (3D) appreciation of complex spatial relationships between implanted stereotactic EEG depth electrodes and surrounding brain and cerebral vasculature are a challenge to clinicians who...

Single-flap versus double-flap approach for periodontal pocket reduction in supraosseous defects: a comparative study.

Journal of periodontal & implant science

Mathala VL, Konathala SVR, Gottumukkala NVSS, Pasupuleti MK, Bypalli V, Korukonda R.
PMID: 34387044
J Periodontal Implant Sci. 2021 Aug;51(4):239-253. doi: 10.5051/jpis.2004200210.

PURPOSE: The single-flap approach (SFA) is a minimally invasive technique with limited mucoperiosteal flap elevation to gain access to the buccal/palatal aspects, thus limiting post-surgical complications. The purpose of the present study was to gain insights into the impact...

Emotional Health Status of Postgraduate Students of Periodontics in India During COVID Health Crisis-A Questionnaire-Based Study.

Journal of patient experience

Pasupuleti MK, Penmetsa GS, Gottumukkala SN, Vintha J, Santosh Vamsi E, Meghana G.
PMID: 34869837
J Patient Exp. 2021 Nov 26;8:23743735211056436. doi: 10.1177/23743735211056436. eCollection 2021.

Dental students, especially postgraduate students present a higher risk of getting infected because of their close contact with the patients during this pandemic. The objectives of the study include (a) the reasons for postgraduate students' altered emotional status during...

Microbiological tests to identify a link between periodontitis and acute myocardial infarction-an original research.

Iranian journal of microbiology

Pasupuleti MK, Nagireddy RR, Dinahalli R, Anumala D, Kishore Kumar A, Chavan V.
PMID: 25848510
Iran J Microbiol. 2013 Dec;5(4):391-5.

BACKGROUND AND OBJECTIVES: Gingival and periodontal diseases are associated with specific bacterial infections. The main aim of the study was to know whether the periodontitis is associated with an increased risk for acute myocardial infarction (AMI) and to know...

Intestinal HIF-2α regulates GLP-1 secretion via lipid sensing in L-cells.

Cellular and molecular gastroenterology and hepatology

Reddy Mooli RG, Mukhi D, Pasupulati AK, Evers SS, Sipula IJ, Jurczak M, Seeley RJ, Shah YM, Ramakrishnan SK.
PMID: 34902628
Cell Mol Gastroenterol Hepatol. 2021 Dec 10; doi: 10.1016/j.jcmgh.2021.12.004. Epub 2021 Dec 10.

BACKGROUND & AIMS: Compelling evidence shows that glucagon-like peptide-1 (GLP-1) has a profound effect in restoring normoglycemia in type 2 diabetic patients by increasing pancreatic insulin secretion. Although L-cells are the primary source of circulating GLP-1, the current therapies...

Ethical guidelines, animal profile, various animal models used in periodontal research with alternatives and future perspectives.

Journal of Indian Society of Periodontology

Pasupuleti MK, Molahally SS, Salwaji S.
PMID: 28298815
J Indian Soc Periodontol. 2016 Jul-Aug;20(4):360-368. doi: 10.4103/0972-124X.186931.

Laboratory animal models serve as a facilitator to investigate the etiopathogenesis of periodontal disease, are used to know the efficacy of reconstructive and regenerative procedures, and are also helpful in evaluation of newer therapeutic techniques including laser and implant...

A Systematic .

Current genomics

Nammi D, Yarla NS, Chubarev VN, Tarasov VV, Barreto GE, Pasupulati AMC, Aliev G, Neelapu NRR.
PMID: 29081700
Curr Genomics. 2017 Oct;18(5):450-465. doi: 10.2174/1389202918666170705160615.

BACKGROUND: Helicobacter pylori is associated with inflammation of different areas, such as the duodenum and stomach, causing gastritis and gastric ulcers leading to lymphoma and cancer. Pathogenic islands are a type of clustered mobile elements ranging from 10-200 Kb...

Showing 1 to 12 of 14 entries