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Showing 1 to 12 of 37 entries
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Electric field and temperature measurement using ultra wide bandwidth pigtailed electro-optic probes.

Applied optics

Bernier M, Gaborit G, Duvillaret L, Paupert A, Lasserre JL.
PMID: 18449315
Appl Opt. 2008 May 01;47(13):2470-6. doi: 10.1364/ao.47.002470.

We present pigtailed electro-optic probes that allow a simultaneous measurement of high frequency electric fields and temperature using a unique laser probe beam. This has been achieved by the development of a novel probe design associated with a fully...

Practical Considerations before Installing Ground-Based Geodetic Infrastructure for Integrated InSAR and cGNSS Monitoring of Vertical Land Motion.

Sensors (Basel, Switzerland)

Parker AL, Featherstone WE, Penna NT, Filmer MS, Garthwaite MC.
PMID: 28758970
Sensors (Basel). 2017 Jul 31;17(8). doi: 10.3390/s17081753.

Continuously operating Global Navigation Satellite Systems (cGNSS) can be used to convert relative values of vertical land motion (VLM) derived from Interferometric Synthetic Aperture Radar (InSAR) to absolute values in a global or regional reference frame. Artificial trihedral corner...

Histone deacetylase inhibitor trichostatin A sensitises cisplatin-resistant ovarian cancer cells to oncolytic adenovirus.

Oncotarget

Hulin-Curtis SL, Davies JA, Jones R, Hudson E, Hanna L, Chester JD, Parker AL.
PMID: 29899862
Oncotarget. 2018 May 29;9(41):26328-26341. doi: 10.18632/oncotarget.25242. eCollection 2018 May 29.

Ovarian cancer is often termed a silent killer due to the late onset of symptoms. Whilst patients initially respond to chemotherapy, they rapidly develop chemo-resistance. Oncolytic adenoviruses (OAds) are promising anti-cancer agents engineered to "hijack" the unique molecular machinery...

Designer Oncolytic Adenovirus: Coming of Age.

Cancers

Baker AT, Aguirre-Hernández C, Halldén G, Parker AL.
PMID: 29904022
Cancers (Basel). 2018 Jun 14;10(6). doi: 10.3390/cancers10060201.

The licensing of talimogene laherparepvec (T-Vec) represented a landmark moment for oncolytic virotherapy, since it provided unequivocal evidence for the long-touted potential of genetically modified replicating viruses as anti-cancer agents. Whilst T-Vec is promising as a locally delivered virotherapy,...

Author Correction: Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1.

Nature immunology

Crowther MD, Dolton G, Legut M, Caillaud ME, Lloyd A, Attaf M, Galloway SAE, Rius C, Farrell CP, Szomolay B, Ager A, Parker AL, Fuller A, Donia M, McCluskey J, Rossjohn J, Svane IM, Phillips JD, Sewell AK.
PMID: 32123375
Nat Immunol. 2020 Jun;21(6):695. doi: 10.1038/s41590-020-0640-6.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Enhanced seed defenses potentially relax selection by seed predators against serotiny in lodgepole pine.

Ecology and evolution

Parker AL, Benkman CW.
PMID: 32607207
Ecol Evol. 2020 May 09;10(12):6001-6008. doi: 10.1002/ece3.6339. eCollection 2020 Jun.

Serotiny, the retention of seeds in a canopy seed bank until high temperatures cause seeds to be released, is an important life history trait for many woody plants in fire-prone habitats. Serotiny provides a competitive advantage after fire but...

Trends and birth outcomes in adolescent refugees and migrants on the Thailand-Myanmar border, 1986-2016: an observational study.

Wellcome open research

Parker AL, Parker DM, Zan BN, Min AM, Gilder ME, Ringringulu M, Win E, Wiladphaingern J, Charunwatthana P, Nosten F, Lee SJ, McGready R.
PMID: 30027124
Wellcome Open Res. 2018 May 21;3:62. doi: 10.12688/wellcomeopenres.14613.1. eCollection 2018.

No abstract available.

Hitting the Target but Missing the Point: Recent Progress towards Adenovirus-Based Precision Virotherapies.

Cancers

Cunliffe TG, Bates EA, Parker AL.
PMID: 33187160
Cancers (Basel). 2020 Nov 11;12(11). doi: 10.3390/cancers12113327.

More people are surviving longer with cancer. Whilst this can be partially attributed to advances in early detection of cancers, there is little doubt that the improvement in survival statistics is also due to the expansion in the spectrum...

How medical students and residents describe the roles and characteristics of their influential clinical teachers.

Academic medicine : journal of the Association of American Medical Colleges

Paukert JL, Richards BF.
PMID: 10965865
Acad Med. 2000 Aug;75(8):843-5. doi: 10.1097/00001888-200008000-00019.

PURPOSE: This study sought to identify students' perceptions about characteristics of faculty who had positively influenced their clinical education and to determine whether the students' perceptions matched those published for residents.METHOD: On exit surveys in 1997 and 1998, students...

High temperature shock tube and theoretical studies on the thermal decomposition of dimethyl carbonate and its bimolecular reactions with H and D-atoms.

The journal of physical chemistry. A

Peukert SL, Sivaramakrishnan R, Michael JV.
PMID: 23510116
J Phys Chem A. 2013 May 09;117(18):3718-28. doi: 10.1021/jp312643k. Epub 2013 Apr 25.

The shock tube technique was used to study the high temperature thermal decomposition of dimethyl carbonate, CH3OC(O)OCH3 (DMC). The formation of H-atoms was measured behind reflected shock waves by using atomic resonance absorption spectrometry (ARAS). The experiments span a...

Tropism-modification strategies for targeted gene delivery using adenoviral vectors.

Viruses

Coughlan L, Alba R, Parker AL, Bradshaw AC, McNeish IA, Nicklin SA, Baker AH.
PMID: 21994621
Viruses. 2010 Oct;2(10):2290-355. doi: 10.3390/v2102290. Epub 2010 Oct 13.

Achieving high efficiency, targeted gene delivery with adenoviral vectors is a long-standing goal in the field of clinical gene therapy. To achieve this, platform vectors must combine efficient retargeting strategies with detargeting modifications to ablate native receptor binding (i.e....

In Vitro and In Vivo Evaluation of Human Adenovirus Type 49 as a Vector for Therapeutic Applications.

Viruses

Bates EA, Counsell JR, Alizert S, Baker AT, Suff N, Boyle A, Bradshaw AC, Waddington SN, Nicklin SA, Baker AH, Parker AL.
PMID: 34452348
Viruses. 2021 Jul 28;13(8). doi: 10.3390/v13081483.

The human adenovirus phylogenetic tree is split across seven species (A-G). Species D adenoviruses offer potential advantages for gene therapy applications, with low rates of pre-existing immunity detected across screened populations. However, many aspects of the basic virology of...

Showing 1 to 12 of 37 entries