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Showing 1 to 12 of 32 entries
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Trajectories and single-particle tracking data of intracellular vesicles loaded with either SNAP-Crb3A or SNAP-Crb3B.

Data in brief

Siebrasse JP, Djuric I, Schulze U, Schlüter MA, Pavenstädt H, Weide T, Kubitscheck U.
PMID: 27222870
Data Brief. 2016 Apr 29;7:1665-9. doi: 10.1016/j.dib.2016.04.058. eCollection 2016 Jun.

Using a combined approach of pulse chase labeling and single-particle tracking of Crb3A or 3B loaded vesicles we collected trajectories of different vesicle population in living podocyte cells and evaluated statistically their different mobility patterns. Differences in their intracellular...

A Low Tacrolimus Concentration/Dose Ratio Increases the Risk for the Development of Acute Calcineurin Inhibitor-Induced Nephrotoxicity.

Journal of clinical medicine

Thölking G, Schütte-Nütgen K, Schmitz J, Rovas A, Dahmen M, Bautz J, Jehn U, Pavenstädt H, Heitplatz B, Van Marck V, Suwelack B, Reuter S.
PMID: 31581670
J Clin Med. 2019 Oct 02;8(10). doi: 10.3390/jcm8101586.

Fast tacrolimus metabolism is linked to inferior outcomes such as rejection and lower renal function after kidney transplantation. Renal calcineurin-inhibitor toxicity is a common adverse effect of tacrolimus therapy. The present contribution hypothesized that tacrolimus-induced nephrotoxicity is related to...

Coronary artery calcium burden, carotid atherosclerotic plaque burden, and myocardial blood flow in patients with end-stage renal disease: A non-invasive imaging study combining PET/CT and 3D ultrasound.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Wenning C, Vrachimis A, Pavenstädt HJ, Reuter S, Schäfers M.
PMID: 32140994
J Nucl Cardiol. 2021 Dec;28(6):2660-2670. doi: 10.1007/s12350-020-02080-w. Epub 2020 Mar 05.

BACKGROUND: Imaging-based measures of atherosclerosis such as coronary artery calcium score (CACS) and coronary flow reserve (CFR) as well as carotid atherosclerotic plaque burden (cPB) are predictors of cardiovascular events in the general population. The objective of this study...

WWC Proteins: Important Regulators of Hippo Signaling in Cancer.

Cancers

Höffken V, Hermann A, Pavenstädt H, Kremerskothen J.
PMID: 33467643
Cancers (Basel). 2021 Jan 15;13(2). doi: 10.3390/cancers13020306.

The Hippo signaling pathway is known to regulate cell differentiation, proliferation and apoptosis. Whereas activation of the Hippo signaling pathway leads to phosphorylation and cytoplasmic retention of the transcriptional coactivator YAP, decreased Hippo signaling results in nuclear import of...

[Isolation precautions, diagnostics and organization in German emergency departments during the 2020 COVID-19 pandemic].

Medizinische Klinik, Intensivmedizin und Notfallmedizin

Finke M, Pin M, Bernhard M, Rovas A, Pavenstädt HJ, Kümpers P.
PMID: 33491106
Med Klin Intensivmed Notfmed. 2021 Jan 24; doi: 10.1007/s00063-021-00775-7. Epub 2021 Jan 24.

BACKGROUND: Since the beginning of the coronavirus disease 19 (COVID-19) pandemic, German emergency departments (ED) have been working in the area of conflict between high case load and demanding hygienic and organizational challenges. The aim of this study was...

Coronary artery calcium burden, carotid atherosclerotic plaque burden, and myocardial blood flow in patients with end-stage renal disease: A non-invasive imaging study combining PET/CT and 3D ultrasound.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Wenning C, Vrachimis A, Pavenstädt HJ, Reuter S, Schäfers M.
PMID: 32140994
J Nucl Cardiol. 2020 Mar 05; doi: 10.1007/s12350-020-02080-w. Epub 2020 Mar 05.

BACKGROUND: Imaging-based measures of atherosclerosis such as coronary artery calcium score (CACS) and coronary flow reserve (CFR) as well as carotid atherosclerotic plaque burden (cPB) are predictors of cardiovascular events in the general population. The objective of this study...

Sex-specific differences and long-term outcome of patients with coronary artery disease and chronic kidney disease: the Coronary Artery Disease and Renal Failure (CAD-REF) Registry.

Clinical research in cardiology : official journal of the German Cardiac Society

Engelbertz C, Pinnschmidt HO, Freisinger E, Reinecke H, Schmitz B, Fobker M, Schmieder RE, Wegscheider K, Breithardt G, Pavenstädt H, Brand E.
PMID: 34036426
Clin Res Cardiol. 2021 Oct;110(10):1625-1636. doi: 10.1007/s00392-021-01864-5. Epub 2021 May 26.

BACKGROUND: Cardiovascular morbidity and mortality are closely linked to chronic kidney disease (CKD). Sex-specific long-term outcome data of patients with coronary artery disease (CAD) and CKD are scarce.METHODS: In the prospective observational multicenter Coronary Artery Disease and REnal Failure...

Prognostic implication of myocardial perfusion and contractile reserve in end-stage renal disease: A direct comparison of myocardial perfusion scintigraphy and dobutamine stress echocardiography.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Bautz J, Stypmann J, Reiermann S, Pavenstädt HJ, Suwelack B, Stegger L, Rahbar K, Reuter S, Schäfers M.
PMID: 34750727
J Nucl Cardiol. 2021 Nov 08; doi: 10.1007/s12350-021-02844-y. Epub 2021 Nov 08.

BACKGROUND: We aimed to compare the prognostic value of myocardial perfusion scintigraphy (MPS) and dobutamine stress echocardiography (DSE) in patients with end-stage renal disease (ESRD) without known coronary artery disease.METHODS: Two-hundred twenty-nine ESRD patients who applied for kidney transplantation...

A Novel Homozygous Mutation in the .

Case reports in nephrology

Jehn U, Müller-Hofstede C, Heitplatz B, Van Marck V, Reuter S, Pavenstädt H, George B.
PMID: 35028164
Case Rep Nephrol. 2022 Jan 04;2022:5243137. doi: 10.1155/2022/5243137. eCollection 2022.

BACKGROUND: Alport syndrome results from a hereditary defect of collagen IV synthesis. This causes progressive glomerular disease, ocular abnormalities, and inner ear impairment. CONCLUSION: This case report highlights the awareness of atypical AS courses and emphasizes the importance of...

Coronary artery calcium burden, carotid atherosclerotic plaque burden, and myocardial blood flow in patients with end-stage renal disease: A non-invasive imaging study combining PET/CT and 3D ultrasound.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Wenning C, Vrachimis A, Pavenstädt HJ, Reuter S, Schäfers M.
PMID: 32140994
J Nucl Cardiol. 2021 Dec;28(6):2660-2670. doi: 10.1007/s12350-020-02080-w. Epub 2020 Mar 05.

BACKGROUND: Imaging-based measures of atherosclerosis such as coronary artery calcium score (CACS) and coronary flow reserve (CFR) as well as carotid atherosclerotic plaque burden (cPB) are predictors of cardiovascular events in the general population. The objective of this study...

α-Galactosidase a Deficiency in Fabry Disease Leads to Extensive Dysregulated Cellular Signaling Pathways in Human Podocytes.

International journal of molecular sciences

Jehn U, Bayraktar S, Pollmann S, Van Marck V, Weide T, Pavenstädt H, Brand E, Lenders M.
PMID: 34768768
Int J Mol Sci. 2021 Oct 20;22(21). doi: 10.3390/ijms222111339.

Fabry disease (FD) is caused by mutations in the α-galactosidase A (

Coronary artery calcium burden, carotid atherosclerotic plaque burden, and myocardial blood flow in patients with end-stage renal disease: A non-invasive imaging study combining PET/CT and 3D ultrasound.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Wenning C, Vrachimis A, Pavenstädt HJ, Reuter S, Schäfers M.
PMID: 32140994
J Nucl Cardiol. 2021 Dec;28(6):2660-2670. doi: 10.1007/s12350-020-02080-w. Epub 2020 Mar 05.

BACKGROUND: Imaging-based measures of atherosclerosis such as coronary artery calcium score (CACS) and coronary flow reserve (CFR) as well as carotid atherosclerotic plaque burden (cPB) are predictors of cardiovascular events in the general population. The objective of this study...

Showing 1 to 12 of 32 entries