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Showing 1 to 12 of 63 entries
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Applying, Evaluating and Refining Bioinformatics Core Competencies (An Update from the Curriculum Task Force of ISCB's Education Committee).

PLoS computational biology

Welch L, Brooksbank C, Schwartz R, Morgan SL, Gaeta B, Kilpatrick AM, Mietchen D, Moore BL, Mulder N, Pauley M, Pearson W, Radivojac P, Rosenberg N, Rosenwald A, Rustici G, Warnow T.
PMID: 27175996
PLoS Comput Biol. 2016 May 13;12(5):e1004943. doi: 10.1371/journal.pcbi.1004943. eCollection 2016 May.

No abstract available.

Synthetic Studies on Lepadiformine Using the 2-Azaallyl Anion Method.

The Journal of organic chemistry

Pearson WH, Ren Y.
PMID: 11674129
J Org Chem. 1999 Feb 05;64(3):688-689. doi: 10.1021/jo982120j.

No abstract available.

2,4,6-Tris-(4-fluoro-phen-yl)-2-(1-pyrid-yl)-boroxine.

Acta crystallographica. Section E, Structure reports online

Pearson WH, Lin S, Iovine PM.
PMID: 21200802
Acta Crystallogr Sect E Struct Rep Online. 2007 Dec 12;64:o235. doi: 10.1107/S1600536807064367.

Crystals of the title compound, C(23)H(17)B(3)F(3)NO(3), were obtained unintentionally by slow evaporation of a chloro-form solution of the preformed boroxine-pyridine adduct. The mol-ecule contains three fluoro-substituted benzene rings, each bonded to one of the three B atoms of a...

Multiple chronic conditions and the aging of america: challenge for primary care physicians.

Journal of primary care & community health

Pearson WS, Bhat-Schelbert K, Probst JC.
PMID: 23804855
J Prim Care Community Health. 2012 Jan 01;3(1):51-6. doi: 10.1177/2150131911414577. Epub 2011 Sep 07.

BACKGROUND: As the United States population ages, chronic conditions are becoming more prevalent and our healthcare system is faced with increasing costs. This aging population with increased multiple chronic conditions coupled with increased burden of disease will provide a...

Impact fragmentation of model flocks.

Physical review. E, Statistical, nonlinear, and soft matter physics

Miller PW, Ouellette NT.
PMID: 24827292
Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Apr;89(4):042806. doi: 10.1103/PhysRevE.89.042806. Epub 2014 Apr 15.

Predicting the bulk material properties of active matter is challenging since these materials are far from equilibrium and standard statistical-mechanics approaches may fail. We report a computational study of the surface properties of a well known active matter system:...

TRANSVENOUS ANEURYSMORRHAPHY: DESCRIPTION OF THE OPERATION.

British medical journal

Pearson W.
PMID: 20769515
Br Med J. 1919 Jun 14;1(3050):736-7. doi: 10.1136/bmj.1.3050.736.

No abstract available.

Application of the 2-Azaallyl Anion Cycloaddition Method to an Enantioselective Total Synthesis of (+)-Coccinine.

Angewandte Chemie (International ed. in English)

Pearson WH, Lian BW.
PMID: 29711499
Angew Chem Int Ed Engl. 1998 Jul 03;37(12):1724-1726. doi: 10.1002/(SICI)1521-3773(19980703)37:12<1724::AID-ANIE1724>3.0.CO;2-8.

A highly functionalized perhydroindole is formed by the intramolecular [π4s+π2s] cycloaddition of a 2-azaallyl anion with a vinyl sulfide [Eq. (a)]. This is the key step in the total synthesis of (+)-coccinine, the enantiomer of the Amaryllidaceae alkaloid (-)-coccinine.

Improvements resulting from respiratory-swallow phase training visualized in patient-specific computational analysis of swallowing mechanics.

Computer methods in biomechanics and biomedical engineering. Imaging & visualization

Tran TTA, Harris BM, Pearson WG.
PMID: 30581689
Comput Methods Biomech Biomed Eng Imaging Vis. 2018;6(5):532-538. doi: 10.1080/21681163.2016.1152567. Epub 2016 Mar 16.

The aim of this study was to visualize improved swallowing mechanics resulting from respiratory-swallow phase training using patient specific computational analysis of Modified Barium Swallow (MBS) videofluoroscopic images. Imaging from a single subject showing improved MBSImP

Functional Modules of Pharyngeal Swallowing Mechanics.

Laryngoscope investigative otolaryngology

Hosseini P, Tadavarthi Y, Martin-Harris B, Pearson WG.
PMID: 31236469
Laryngoscope Investig Otolaryngol. 2019 May 10;4(3):341-346. doi: 10.1002/lio2.273. eCollection 2019 Jun.

OBJECTIVES: The present retrospective cohort study aims to test the hypothesis that elements of swallowing mechanics including hyoid movement, laryngeal elevation, tongue base retraction, pharyngeal shortening, pharyngeal constriction, and head and neck extension can be grouped into functional modules,...

Geometry of Wave Propagation on Active Deformable Surfaces.

Physical review letters

Miller PW, Stoop N, Dunkel J.
PMID: 30004728
Phys Rev Lett. 2018 Jun 29;120(26):268001. doi: 10.1103/PhysRevLett.120.268001.

Fundamental biological and biomimetic processes, from tissue morphogenesis to soft robotics, rely on the propagation of chemical and mechanical surface waves to signal and coordinate active force generation. The complex interplay between surface geometry and contraction wave dynamics remains...

The Burden of and Trends in Pelvic Inflammatory Disease in the United States, 2006-2016.

The Journal of infectious diseases

Kreisel KM, Llata E, Haderxhanaj L, Pearson WS, Tao G, Wiesenfeld HC, Torrone EA.
PMID: 34396411
J Infect Dis. 2021 Aug 16;224(12):S103-S112. doi: 10.1093/infdis/jiaa771.

BACKGROUND: Pelvic inflammatory disease (PID) is an infection of the upper genital tract that has important reproductive consequences to women. We describe the burden of and trends in PID among reproductive-aged women in the United States during 2006-2016.METHODS: We...

Topological braiding and virtual particles on the cell membrane.

Proceedings of the National Academy of Sciences of the United States of America

Liu J, Totz JF, Miller PW, Hastewell AD, Chao YC, Dunkel J, Fakhri N.
PMID: 34417290
Proc Natl Acad Sci U S A. 2021 Aug 24;118(34). doi: 10.1073/pnas.2104191118.

Braiding of topological structures in complex matter fields provides a robust framework for encoding and processing information, and it has been extensively studied in the context of topological quantum computation. In living systems, topological defects are crucial for the...

Showing 1 to 12 of 63 entries