Molecular therapy oncolytics

Illingworth S, Di Y, Bauzon M, Lei J, Duffy MR, Alvis S, Champion B, Lieber A, Hermiston T, Seymour LW, Beadle J, Fisher K.
PMID: 28480328
Mol Ther Oncolytics. 2017 Mar 29;5:62-74. doi: 10.1016/j.omto.2017.03.003. eCollection 2017 Jun 16.

Enadenotucirev is an oncolytic group B adenovirus identified by a process of bio-selection for the ability to selectively propagate in and rapidly kill carcinoma cells. It is resistant to inactivation by human blood components, potentially enabling intravenous dosing in...

JMIR public health and surveillance

Hohl CM, Small SS, Peddie D, Badke K, Bailey C, Balka E.
PMID: 29487041
JMIR Public Health Surveill. 2018 Feb 27;4(1):e21. doi: 10.2196/publichealth.9282.

BACKGROUND: Adverse drug events are unintended and harmful events related to medications. Adverse drug events are important for patient care, quality improvement, drug safety research, and postmarketing surveillance, but they are vastly underreported.OBJECTIVE: Our objectives were to identify barriers...

The Canadian journal of hospital pharmacy

Dillon C, Peddle J, Twells L, Lester K, Midodzi W, Manning K, Murphy R, Pace D, Smith C, Boone D, Gregory D.
PMID: 25964682
Can J Hosp Pharm. 2015 Mar-Apr;68(2):113-20. doi: 10.4212/cjhp.v68i2.1436.

BACKGROUND: Patients who have undergone bariatric surgery generally need fewer medications as they experience improvement in, or even resolution of, various medical conditions, including type 2 diabetes mellitus, hypertension, and dyslipidemia. Published data on changes in medication use after...

Computational and structural biotechnology journal

Zaucha J, Heddle JG.
PMID: 28652896
Comput Struct Biotechnol J. 2017 May 30;15:351-358. doi: 10.1016/j.csbj.2017.05.002. eCollection 2017.

Biological molecules, like organisms themselves, are subject to genetic drift and may even become "extinct". Molecules that are no longer extant in living systems are of high interest for several reasons including insight into how existing life forms evolved...

Journal of cachexia, sarcopenia and muscle

Stewart Coats AJ, Ho GF, Prabhash K, von Haehling S, Tilson J, Brown R, Beadle J, Anker SD.
PMID: 27386169
J Cachexia Sarcopenia Muscle. 2016 Jun;7(3):355-65. doi: 10.1002/jcsm.12126. Epub 2016 Jul 01.

BACKGROUND: Cancer cachexia is a major cause of morbidity and mortality with no widely approved treatment.METHODS: The ACT-ONE trial is a randomized, double-blind, parallel group, placebo-controlled, phase II multicentre trial in patients (25-80 years) with stages III or IV...

Physical review letters

Carman DS, Joo K, Mestayer MD, Raue BA, Adams G, Ambrozewicz P, Anciant E, Anghinolfi M, Armstrong DS, Asavapibhop B, Audit G, Auger T, Avakian H, Bagdasaryan H, Ball JP, Barrow SP, Battaglieri M, Beard K, Bektasoglu M, Bellis M, Bennhold C, Bianchi N, Biselli AS, Boiarinov S, Bonner BE, Bouchigny S, Bradford R, Branford D, Briscoe WJ, Brooks WK, Burkert VD, Butuceanu C, Calarco JR, Carnahan B, Cazes A, Cetina C, Ciciani L, Clark R, Cole PL, Coleman A, Cords D, Corvisiero P, Crabb D, Crannell H, Cummings JP, DeSanctis E, Degtyarenko PV, Denizli H, Dennis L, DeVita R, Dharmawardane KV, Dhuga KS, Djalali C, Dodge GE, Doughty D, Dragovitsch P, Dugger M, Dytman S, Dzyubak OP, Eckhause M, Egiyan H, Egiyan KS, Elouadrhiri L, Empl A, Eugenio P, Fatemi R, Fedotov G, Feuerbach RJ, Ficenec J, Forest TA, Funsten H, Gaff SJ, Gai M, Garçon M, Gavalian G, Gilad S, Gilfoyle GP, Giovanetti KL, Girard P, Golovach E, Gordon CI, Griffioen K, Grimes S, Guidal M, Guillo M, Guo L, Gyurjyan V, Hadjidakis C, Hakobyan RS, Hardie J, Heddle D, Heimberg P, Hersman FW, Hicks K, Hicks RS, Holtrop M, Hu J, Hyde-Wright CE, Ishkhanov B, Ito MM, Jenkins D, Kelley JH, Kellie JD, Khandaker M, Kim KY, Kim K, Kim W, Klein A, Klein FJ, Klimenko AV, Klusman M, Kossov M, Kramer LH, Kuang Y, Kuhn SE, Kuhn J, Lachniet J, Laget JM, Lawrence D, Li J, Livingston K, Longhi A, Lukashin K, Manak JJ, Marchand C, Mart T, McAleer S, McCarthy J, McNabb JW, Mecking BA, Mehrabyan S, Melone JJ, Meyer CA, Mikhailov K, Minehart R, Mirazita M, Miskimen R, Mokeev V, Morand L, Morrow SA, Mozer MU, Muccifora V, Mueller J, Murphy LY, Mutchler GS, Napolitano J, Nasseripour R, Nelson SO, Niccolai S, Niculescu G, Niculescu I, Niczyporuk BB, Niyazov RA, Nozar M, O'Rielly GV, Opper AK, Osipenko M, Park K, Paschke K, Pasyuk E, Peterson G, Pivnyuk N, Pocanic D, Pogorelko O, Polli E, Pozdniakov S, Preedom BM, Price JW, Prok Y, Protopopescu D, Qin LM, Riccardi G, Ricco G, Ripani M, Ritchie BG, Ronchetti F, Rossi P, Rowntree D, Rubin P, Sabatié F, Sabourov K, Salgado C, Santoro J, Sapunenko V, Schumacher RA, Serov VS, Sharabian YG, Shaw J, Simionatto S, Skabelin AV, Smith ES, Smith LC, Sober DI, Spraker M, Stavinsky A, Stepanyan S, Stoler P, Taiuti M, Taylor S, Tedeschi DJ, Thoma U, Thompson R, Todor L, Tur C, Ungaro M, Vineyard MF, Vlassov AV, Wang K, Weinstein LB, Weller H, Weygand DP, Whisnant CS, Wolin E, Wood MH, Yegneswaran A, Yun J, Zhang B, Zhao J, Zhou Z.
PMID: 12689277
Phys Rev Lett. 2003 Apr 04;90(13):131804. doi: 10.1103/PhysRevLett.90.131804. Epub 2003 Apr 04.

The first measurements of the transferred polarization for the exclusive e-->p-->e(')K+Lambda--> reaction have been performed at Jefferson Laboratory using the CLAS spectrometer. A 2.567 GeV beam was used to measure the hyperon polarization over Q2 from 0.3 to 1.5...

Physical review letters

Joo K, Smith LC, Burkert VD, Minehart R, Aznauryan IG, Elouadrhiri L, Stepanyan S, Adams GS, Amaryan MJ, Anciant E, Anghinolfi M, Armstrong DS, Asavapibhop B, Audit G, Auger T, Avakian H, Barrow S, Bagdasaryan H, Battaglieri M, Beard K, Bektasoglu M, Bertozzi W, Bianchi N, Biselli AS, Boiarinov S, Bonner BE, Brooks WK, Calarco JR, Capitani GP, Carman DS, Carnahan B, Cole PL, Coleman A, Cords D, Corvisiero P, Crabb D, Crannell H, Cummings J, De Sanctis E, De Vita R, Degtyarenko PV, Demirchyan RA, Denizli H, Dennis LC, Deppman A, Dharmawardane KV, Dhuga KS, Djalali C, Dodge GE, Doughty D, Dragovitsch P, Dugger M, Dytman S, Eckhause M, Efremenko YV, Egiyan H, Egiyan KS, Farhi L, Feuerbach RJ, Ficenec J, Fissum K, Forest TA, Funsten H, Gai M, Gavrilov VB, Gilad S, Gilfoyle GP, Giovanetti KL, Girard P, Griffioen KA, Guidal M, Guillo M, Gyurjyan V, Hancock D, Hardie J, Heddle D, Heisenberg J, Hersman FW, Hicks K, Hicks RS, Holtrop M, Hyde-Wright CE, Ito MM, Jenkins D, Kelley JH, Khandaker M, Kim KY, Kim W, Klein A, Klein FJ, Klusman M, Kossov M, Kuang Y, Kuhn SE, Laget JM, Lawrence D, Longhi A, Loukachine K, Lucas M, Major RW, Manak JJ, Marchand C, Matthews SK, McAleer S, McNabb JW, Mecking BA, Mestayer MD, Meyer CA, Mirazita M, Miskimen R, Muccifora V, Mueller J, Mutchler GS, Napolitano J, Niculescu G, Niczyporuk B, Niyazov RA, Ohandjanyan MS, Opper A, Patois Y, Peterson GA, Philips S, Pivnyuk N, Pocanic D, Pogorelko O, Polli E, Preedom BM, Price JW, Qin LM, Raue BA, Reolon AR, Riccardi G, Ricco G, Ripani M, Ritchie BG, Ronchetti F, Rossi P, Rowntree D, Rubin PD, Salgado CW, Sanzone M, Sapunenko V, Sargsyan M, Schumacher RA, Sharabian YG, Shaw J, Shuvalov SM, Skabelin A, Smith ES, Smith T, Sober DI, Spraker M, Stoler P, Taiuti M, Taylor S, Tedeschi D, Thompson R, Todor L, Tung TY, Vineyard MF, Vlassov A, Weller H, Weinstein LB, Welsh R, Weygand DP, Whisnant S, Witkowski M, Wolin E, Yegneswaran A, Yun J, Zhou Z, Zhao J.
PMID: 11909446
Phys Rev Lett. 2002 Mar 25;88(12):122001. doi: 10.1103/PhysRevLett.88.122001. Epub 2002 Mar 06.

Models of baryon structure predict a small quadrupole deformation of the nucleon due to residual tensor forces between quarks or distortions from the pion cloud. Sensitivity to quark versus pion degrees of freedom occurs through the Q2 dependence of...

Immunohematology

Haslam GM, Sajur J, Fournier Y, Aulph J, Persaud M, Heddle N.
PMID: 15447071
Immunohematology. 1995;11(1):8-10.

Two solid phase methods of antibody detection, Capture-R (CR) and Capture-R Ready-Screen (RS), were compared to determine their acceptability for use in prenatal antibody screening. Ninety-six serum samples, screened using a saline antiglobulin test, were coded and tested by...

Physical review letters

Stepanyan S, Hicks K, Carman DS, Pasyuk E, Schumacher RA, Smith ES, Tedeschi DJ, Todor L, Adams G, Ambrozewicz P, Anciant E, Anghinolfi M, Asavapibhop B, Audit G, Avakian H, Bagdasaryan H, Ball JP, Barrow SP, Battaglieri M, Beard K, Bektasoglu M, Bellis M, Berman BL, Bianchi N, Biselli AS, Boiarinov S, Bouchigny S, Bradford R, Branford D, Briscoe WJ, Brooks WK, Burkert VD, Butuceanu C, Calarco JR, Carnahan B, Chen S, Ciciani L, Cole PL, Coleman A, Cords D, Corvisiero P, Crabb D, Crannell H, Cummings JP, De Sanctis E, Degtyarenko PV, Denizli H, Dennis L, De Vita R, Dharmawardane KV, Dhuga KS, Djalali C, Dodge GE, Doughty D, Dragovitsch P, Dugger M, Dytman S, Dzyubak OP, Egiyan H, Egiyan KS, Elouadrhiri L, Empl A, Eugenio P, Fatemi R, Feuerbach RJ, Ficenec J, Forest TA, Funsten H, Garçon M, Gavalian G, Gilfoyle GP, Giovanetti KL, Gordon CI, Gothe R, Griffioen K, Guidal M, Guillo M, Guo L, Gyurjyan V, Hadjidakis C, Hakobyan RS, Hardie J, Heddle D, Heimberg P, Hersman FW, Hicks RS, Holtrop M, Hu J, Hyde-Wright CE, Ito MM, Jenkins D, Joo K, Juengst HG, Kellie JD, Khandaker M, Kim KY, Kim K, Kim W, Klein A, Klein FJ, Klimenko AV, Klusman M, Kossov M, Kramer LH, Kuang Y, Kubarovsky V, Kuhn SE, Kuhn J, Lachniet J, Lawrence D, Li J, Lima A, Livingston K, Lukashin K, Manak JJ, McAleer S, McNabb JW, Mecking BA, Mehrabyan S, Melone JJ, Mestayer MD, Meyer CA, Mikhailov K, Minehart R, Mirazita M, Miskimen R, Mokeev V, Morand L, Morrow S, Muccifora V, Mueller J, Murphy LY, Mutchler GS, Napolitano J, Nasseripour R, Niccolai S, Niculescu G, Niculescu I, Niczyporuk BB, Niyazov RA, Nozar M, O'Brien J, O'Rielly GV, Opper AK, Osipenko M, Park K, Peterson G, Philips SA, Pivnyuk N, Pocanic D, Pogorelko O, Polli E, Pozdniakov S, Preedom BM, Price JW, Prok Y, Protopopescu D, Qin LM, Raue BA, Riccardi G, Ricco G, Ripani M, Ritchie BG, Ronchetti F, Rossi P, Rowntree D, Rubin P, Sabatié F, Salgado C, Santoro J, Sapunenko V, Serov VS, Sharabian YG, Shaw J, Simionatto S, Skabelin AV, Smith LC, Sober DI, Strakovsky II, Stavinsky A, Stoler P, Suleiman R, Taiuti M, Taylor S, Thoma U, Thompson R, Tur C, Ungaro M, Vineyard MF, Vlassov AV, Wang K, Weinstein LB, Weller H, Weygand DP, Whisnant CS, Wolin E, Wood MH, Yegneswaran A, Yun J.
PMID: 14754107
Phys Rev Lett. 2003 Dec 19;91(25):252001. doi: 10.1103/PhysRevLett.91.252001. Epub 2003 Dec 19.

In an exclusive measurement of the reaction gammad-->K(+)K(-)pn, a narrow peak that can be attributed to an exotic baryon with strangeness S=+1 is seen in the K(+)n invariant mass spectrum. The peak is at 1.542+/-0.005 GeV/c(2) with a measured...

Journal of youth and adolescence

Harden KP, Mendle J, Hill JE, Turkheimer E, Emery RE.
PMID: 21479148
J Youth Adolesc. 2008 Apr;37(4):373-385. doi: 10.1007/s10964-007-9228-9.

The relation between timing of first sex and later delinquency was examined using a genetically informed sample of 534 same-sex twin pairs from the National Longitudinal Study of Adolescent Health, who were assessed at three time points over a...

Journal of diabetes science and technology

Adolfsson P, Ornhagen H, Jendle J.
PMID: 19885260
J Diabetes Sci Technol. 2008 Sep;2(5):778-84. doi: 10.1177/193229680800200505.

BACKGROUND: Our objective is to evaluate the Medtronic CGMS continuous glucose monitoring system and plasma glucose (PG) measurement performed in a monitoring schedule as tools to identify individuals with type 1 diabetes at risk when diving.METHODS: We studied 24...

Physical review letters

Nozar M, Salgado C, Weygand DP, Guo L, Adams G, Li J, Eugenio P, Amaryan MJ, Anghinolfi M, Asryan G, Avakian H, Bagdasaryan H, Baillie N, Ball JP, Baltzell NA, Barrow S, Battaglieri M, Bedlinskiy I, Bektasoglu M, Bellis M, Benmouna N, Berman BL, Biselli AS, Blaszczyk L, Bonner BE, Bouchigny S, Boiarinov S, Bradford R, Branford D, Briscoe WJ, Brooks WK, Bültmann S, Burkert VD, Butuceanu C, Calarco JR, Careccia SL, Carman DS, Carnahan B, Casey L, Cazes A, Chen S, Cheng L, Cole PL, Collins P, Coltharp P, Cords D, Corvisiero P, Crabb D, Crannell H, Crede V, Cummings JP, Dale D, Dashyan N, De Masi R, De Vita R, De Sanctis E, Degtyarenko PV, Denizli H, Dennis L, Deur A, Dharmawardane KV, Dhuga KS, Dickson R, Djalali C, Dodge GE, Doughty D, Dugger M, Dytman S, Dzyubak OP, Egiyan H, Egiyan KS, El Fassi L, Elouadrhiri L, Fatemi R, Fedotov G, Feuerbach RJ, Forest TA, Fradi A, Funsten H, Garçon M, Gavalian G, Gevorgyan N, Gilfoyle GP, Giovanetti KL, Girod FX, Goetz JT, Gothe RW, Griffioen KA, Guidal M, Guillo M, Guler N, Gyurjyan V, Hadjidakis C, Hafidi K, Hakobyan H, Hanretty C, Hardie J, Hassall N, Heddle D, Hersman FW, Hicks K, Hleiqawi I, Holtrop M, Hyde-Wright CE, Ilieva Y, Ireland DG, Ishkhanov BS, Isupov EL, Ito MM, Jenkins D, Jo HS, Johnstone JR, Joo K, Juengst HG, Kalantarians N, Kellie JD, Khandaker M, Kim W, Klein A, Klein FJ, Kossov M, Krahn Z, Kramer LH, Kubarovsky V, Kuhn J, Kuhn SE, Kuleshov SV, Kuznetsov V, Lachniet J, Laget JM, Langheinrich J, Lawrence D, Livingston K, Lu HY, Maccormick M, Markov N, Mattione P, McAleer S, McKinnon B, McNabb JW, Mecking BA, Mehrabyan S, Mestayer MD, Meyer CA, Mibe T, Mikhailov K, Mirazita M, Miskimen R, Mokeev V, Moreno B, Moriya K, Morrow SA, Moteabbed M, Mueller J, Munevar E, Mutchler GS, Nadel-Turonski P, Nasseripour R, Niccolai S, Niculescu G, Niculescu I, Niczyporuk BB, Niroula MR, Niyazov RA, O'Rielly GV, Osipenko M, Ostrovidov AI, Park K, Pasyuk E, Paterson C, Anefalos Pereira S, Philips SA, Pierce J, Pivnyuk N, Pocanic D, Pogorelko O, Polli E, Popa I, Pozdniakov S, Preedom BM, Price JW, Prok Y, Protopopescu D, Qin LM, Raue BA, Riccardi G, Ricco G, Ripani M, Ritchie BG, Ronchetti F, Rosner G, Rossi P, Rubin PD, Sabatié F, Salamanca J, Santoro JP, Sapunenko V, Schumacher RA, Serov VS, Sharabian YG, Sharov D, Shvedunov NV, Skabelin AV, Smith ES, Smith LC, Sober DI, Sokhan D, Stavinsky A, Stepanyan SS, Stepanyan S, Stokes BE, Stoler P, Strakovsky II, Strauch S, Taiuti M, Tedeschi DJ, Thoma U, Tkabladze A, Tkachenko S, Todor L, Ungaro M, Vineyard MF, Vlassov AV, Watts DP, Weinstein LB, Williams M, Wolin E, Wood MH, Yegneswaran A, Zana L, Zhang J, Zhao B, Zhao ZW.
PMID: 19392105
Phys Rev Lett. 2009 Mar 13;102(10):102002. doi: 10.1103/PhysRevLett.102.102002. Epub 2009 Mar 12.

A search for exotic mesons in the pi;{+}pi;{+}pi;{-} system photoproduced by the charge exchange reaction gammap-->pi;{+}pi;{+}pi;{-}(n) was carried out by the CLAS Collaboration at Jefferson Lab. A tagged-photon beam with energies in the 4.8 to 5.4 GeV range, produced...