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Assessing Rab5 Activation in Health and Disease.

Methods in molecular biology (Clifton, N.J.)

Pensalfini A, Jiang Y, Kim S, Nixon RA.
PMID: 34453725
Methods Mol Biol. 2021;2293:273-294. doi: 10.1007/978-1-0716-1346-7_20.

The endocytic pathway is a system of dynamically communicating vesicles, known as early endosomes, that internalize, sort, and traffic nutrients, trophic factors, and signaling molecules to sites throughout the cell. In all eukaryotic cells, early endosome functions are regulated...

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Pensalfini A, Jiang Y, Kim S, et al. Assessing Rab5 Activation in Health and Disease. Methods Mol Biol. 2021;2293:273-294doi: 10.1007/978-1-0716-1346-7_20.
Pensalfini, A., Jiang, Y., Kim, S., & Nixon, R. A. (2021). Assessing Rab5 Activation in Health and Disease. Methods in molecular biology (Clifton, N.J.), 2293273-294. https://doi.org/10.1007/978-1-0716-1346-7_20
Pensalfini, Anna, et al. "Assessing Rab5 Activation in Health and Disease." Methods in molecular biology (Clifton, N.J.) vol. 2293 (2021): 273-294. doi: https://doi.org/10.1007/978-1-0716-1346-7_20
Pensalfini A, Jiang Y, Kim S, Nixon RA. Assessing Rab5 Activation in Health and Disease. Methods Mol Biol. 2021;2293:273-294. doi: 10.1007/978-1-0716-1346-7_20. PMID: 34453725; PMCID: PMC8488988.
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Carbapenem-resistant bacteria in an intensive care unit during the coronavirus disease 2019 (COVID-19) pandemic: A multicenter before-and-after cross-sectional study.

Infection control and hospital epidemiology

Pascale R, Bussini L, Gaibani P, Bovo F, Fornaro G, Lombardo D, Ambretti S, Pensalfine G, Appolloni L, Bartoletti M, Tedeschi S, Tumietto F, Lewis R, Viale P, Giannella M.
PMID: 33858547
Infect Control Hosp Epidemiol. 2021 Apr 16;1-6. doi: 10.1017/ice.2021.144. Epub 2021 Apr 16.

OBJECTIVE: To assess the incidence of colonization and infection with carbapenemase-producing Enterobacteriaceae (CPE) and carbapenem-resistant Acinetobacter baumannii (CR-Ab) in the ICUs of our city hospitals before and during the coronavirus disease 2019 (COVID-19) pandemic.METHODS: We conducted a multicenter, before-and-after,...

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Pascale R, Bussini L, Gaibani P, et al. Carbapenem-resistant bacteria in an intensive care unit during the coronavirus disease 2019 (COVID-19) pandemic: A multicenter before-and-after cross-sectional study. Infect Control Hosp Epidemiol. 2021;1-6doi: 10.1017/ice.2021.144.
Pascale, R., Bussini, L., Gaibani, P., Bovo, F., Fornaro, G., Lombardo, D., Ambretti, S., Pensalfine, G., Appolloni, L., Bartoletti, M., Tedeschi, S., Tumietto, F., Lewis, R., Viale, P., & Giannella, M. (2021). Carbapenem-resistant bacteria in an intensive care unit during the coronavirus disease 2019 (COVID-19) pandemic: A multicenter before-and-after cross-sectional study. Infection control and hospital epidemiology, 1-6. https://doi.org/10.1017/ice.2021.144
Pascale, Renato, et al. "Carbapenem-resistant bacteria in an intensive care unit during the coronavirus disease 2019 (COVID-19) pandemic: A multicenter before-and-after cross-sectional study." Infection control and hospital epidemiology vol. (2021): 1-6. doi: https://doi.org/10.1017/ice.2021.144
Pascale R, Bussini L, Gaibani P, Bovo F, Fornaro G, Lombardo D, Ambretti S, Pensalfine G, Appolloni L, Bartoletti M, Tedeschi S, Tumietto F, Lewis R, Viale P, Giannella M. Carbapenem-resistant bacteria in an intensive care unit during the coronavirus disease 2019 (COVID-19) pandemic: A multicenter before-and-after cross-sectional study. Infect Control Hosp Epidemiol. 2021 Apr 16;1-6. doi: 10.1017/ice.2021.144. Epub 2021 Apr 16. PMID: 33858547; PMCID: PMC8365044.
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Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease.

Cell reports

Pensalfini A, Kim S, Subbanna S, Bleiwas C, Goulbourne CN, Stavrides PH, Jiang Y, Lee JH, Darji S, Pawlik M, Huo C, Peddy J, Berg MJ, Smiley JF, Basavarajappa BS, Nixon RA.
PMID: 33238112
Cell Rep. 2020 Nov 24;33(8):108420. doi: 10.1016/j.celrep.2020.108420.

Neuronal endosomal dysfunction, the earliest known pathobiology specific to Alzheimer's disease (AD), is mediated by the aberrant activation of Rab5 triggered by APP-β secretase cleaved C-terminal fragment (APP-βCTF). To distinguish pathophysiological consequences specific to overactivated Rab5 itself, we activate...

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Pensalfini A, Kim S, Subbanna S, et al. Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease. Cell Rep. 2020;33(8):108420doi: 10.1016/j.celrep.2020.108420.
Pensalfini, A., Kim, S., Subbanna, S., Bleiwas, C., Goulbourne, C. N., Stavrides, P. H., Jiang, Y., Lee, J. H., Darji, S., Pawlik, M., Huo, C., Peddy, J., Berg, M. J., Smiley, J. F., Basavarajappa, B. S., & Nixon, R. A. (2020). Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease. Cell reports, 33(8), 108420. https://doi.org/10.1016/j.celrep.2020.108420
Pensalfini, Anna, et al. "Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease." Cell reports vol. 33,8 (2020): 108420. doi: https://doi.org/10.1016/j.celrep.2020.108420
Pensalfini A, Kim S, Subbanna S, Bleiwas C, Goulbourne CN, Stavrides PH, Jiang Y, Lee JH, Darji S, Pawlik M, Huo C, Peddy J, Berg MJ, Smiley JF, Basavarajappa BS, Nixon RA. Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease. Cell Rep. 2020 Nov 24;33(8):108420. doi: 10.1016/j.celrep.2020.108420. PMID: 33238112; PMCID: PMC7714675.
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Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers.

Molecular neurodegeneration

Kayed R, Canto I, Breydo L, Rasool S, Lukacsovich T, Wu J, Albay R, Pensalfini A, Yeung S, Head E, Marsh JL, Glabe C.
PMID: 21144050
Mol Neurodegener. 2010 Dec 13;5:57. doi: 10.1186/1750-1326-5-57.

BACKGROUND: Age-related neurodegenerative diseases share a number of important pathological features, such as accumulation of misfolded proteins as amyloid oligomers and fibrils. Recent evidence suggests that soluble amyloid oligomers and not the insoluble amyloid fibrils may represent the primary...

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Kayed R, Canto I, Breydo L, et al. Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers. Mol Neurodegener. 2010;5:57doi: 10.1186/1750-1326-5-57.
Kayed, R., Canto, I., Breydo, L., Rasool, S., Lukacsovich, T., Wu, J., Albay, R., Pensalfini, A., Yeung, S., Head, E., Marsh, J. L., & Glabe, C. (2010). Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers. Molecular neurodegeneration, 557. https://doi.org/10.1186/1750-1326-5-57
Kayed, Rakez, et al. "Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers." Molecular neurodegeneration vol. 5 (2010): 57. doi: https://doi.org/10.1186/1750-1326-5-57
Kayed R, Canto I, Breydo L, Rasool S, Lukacsovich T, Wu J, Albay R, Pensalfini A, Yeung S, Head E, Marsh JL, Glabe C. Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers. Mol Neurodegener. 2010 Dec 13;5:57. doi: 10.1186/1750-1326-5-57. PMID: 21144050; PMCID: PMC3019145.
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Publisher Correction: Tear resistance of soft collagenous tissues.

Nature communications

Bircher K, Zündel M, Pensalfini M, Ehret AE, Mazza E.
PMID: 31147555
Nat Commun. 2019 May 30;10(1):2435. doi: 10.1038/s41467-019-10560-y.

The original version of this Article contained errors in the 'Computational material models' section of the Methods in which some values were displayed with incorrect units. As a result of this, a number of changes have been made to...

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Bircher K, Zündel M, Pensalfini M, et al. Publisher Correction: Tear resistance of soft collagenous tissues. Nat Commun. 2019;10(1):2435doi: 10.1038/s41467-019-10560-y.
Bircher, K., Zündel, M., Pensalfini, M., Ehret, A. E., & Mazza, E. (2019). Publisher Correction: Tear resistance of soft collagenous tissues. Nature communications, 10(1), 2435. https://doi.org/10.1038/s41467-019-10560-y
Bircher, Kevin, et al. "Publisher Correction: Tear resistance of soft collagenous tissues." Nature communications vol. 10,1 (2019): 2435. doi: https://doi.org/10.1038/s41467-019-10560-y
Bircher K, Zündel M, Pensalfini M, Ehret AE, Mazza E. Publisher Correction: Tear resistance of soft collagenous tissues. Nat Commun. 2019 May 30;10(1):2435. doi: 10.1038/s41467-019-10560-y. PMID: 31147555; PMCID: PMC6542790.
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Showing 1 to 5 of 5 entries