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Conditional Depletion of the Chlamydomonas Chloroplast ClpP Protease Activates Nuclear Genes Involved in Autophagy and Plastid Protein Quality Control.

The Plant cell

Ramundo S, Casero D, Mühlhaus T, Hemme D, Sommer F, Crèvecoeur M, Rahire M, Schroda M, Rusch J, Goodenough U, Pellegrini M, Perez-Perez ME, Crespo JL, Schaad O, Civic N, Rochaix JD.
PMID: 24879428
Plant Cell. 2014 May;26(5):2201-2222. doi: 10.1105/tpc.114.124842. Epub 2014 May 30.

Plastid protein homeostasis is critical during chloroplast biogenesis and responses to changes in environmental conditions. Proteases and molecular chaperones involved in plastid protein quality control are encoded by the nucleus except for the catalytic subunit of ClpP, an evolutionarily...

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Ramundo S, Casero D, Mühlhaus T, et al. Conditional Depletion of the Chlamydomonas Chloroplast ClpP Protease Activates Nuclear Genes Involved in Autophagy and Plastid Protein Quality Control. Plant Cell. 2014;26(5):2201-2222doi: 10.1105/tpc.114.124842.
Ramundo, S., Casero, D., Mühlhaus, T., Hemme, D., Sommer, F., Crèvecoeur, M., Rahire, M., Schroda, M., Rusch, J., Goodenough, U., Pellegrini, M., Perez-Perez, M. E., Crespo, J. L., Schaad, O., Civic, N., & Rochaix, J. D. (2014). Conditional Depletion of the Chlamydomonas Chloroplast ClpP Protease Activates Nuclear Genes Involved in Autophagy and Plastid Protein Quality Control. The Plant cell, 26(5), 2201-2222. https://doi.org/10.1105/tpc.114.124842
Ramundo, Silvia, et al. "Conditional Depletion of the Chlamydomonas Chloroplast ClpP Protease Activates Nuclear Genes Involved in Autophagy and Plastid Protein Quality Control." The Plant cell vol. 26,5 (2014): 2201-2222. doi: https://doi.org/10.1105/tpc.114.124842
Ramundo S, Casero D, Mühlhaus T, Hemme D, Sommer F, Crèvecoeur M, Rahire M, Schroda M, Rusch J, Goodenough U, Pellegrini M, Perez-Perez ME, Crespo JL, Schaad O, Civic N, Rochaix JD. Conditional Depletion of the Chlamydomonas Chloroplast ClpP Protease Activates Nuclear Genes Involved in Autophagy and Plastid Protein Quality Control. Plant Cell. 2014 May;26(5):2201-2222. doi: 10.1105/tpc.114.124842. Epub 2014 May 30. PMID: 24879428; PMCID: PMC4079378.
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Community differentiation of the cutaneous microbiota in psoriasis.

Microbiome

Alekseyenko AV, Perez-Perez GI, De Souza A, Strober B, Gao Z, Bihan M, Li K, Methé BA, Blaser MJ.
PMID: 24451201
Microbiome. 2013 Dec 23;1(1):31. doi: 10.1186/2049-2618-1-31.

BACKGROUND: Psoriasis is a common chronic inflammatory disease of the skin. We sought to characterize and compare the cutaneous microbiota of psoriatic lesions (lesion group), unaffected contralateral skin from psoriatic patients (unaffected group), and similar skin loci in matched...

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Alekseyenko AV, Perez-Perez GI, De Souza A, et al. Community differentiation of the cutaneous microbiota in psoriasis. Microbiome. 2013;1(1):31doi: 10.1186/2049-2618-1-31.
Alekseyenko, A. V., Perez-Perez, G. I., De Souza, A., Strober, B., Gao, Z., Bihan, M., Li, K., Methé, B. A., & Blaser, M. J. (2013). Community differentiation of the cutaneous microbiota in psoriasis. Microbiome, 1(1), 31. https://doi.org/10.1186/2049-2618-1-31
Alekseyenko, Alexander V, et al. "Community differentiation of the cutaneous microbiota in psoriasis." Microbiome vol. 1,1 (2013): 31. doi: https://doi.org/10.1186/2049-2618-1-31
Alekseyenko AV, Perez-Perez GI, De Souza A, Strober B, Gao Z, Bihan M, Li K, Methé BA, Blaser MJ. Community differentiation of the cutaneous microbiota in psoriasis. Microbiome. 2013 Dec 23;1(1):31. doi: 10.1186/2049-2618-1-31. PMID: 24451201; PMCID: PMC4177411.
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Rapid identification of .

The journal of pathology. Clinical research

Demiray-Gürbüz E, Yılmaz Ö, Olivares AZ, Gönen C, Sarıoğlu S, Soytürk M, Tümer S, Altungöz O, Şimşek İ, Perez Perez GI.
PMID: 28138399
J Pathol Clin Res. 2016 Nov 26;3(1):29-37. doi: 10.1002/cjp2.57. eCollection 2017 Jan.

No abstract available.

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Demiray-Gürbüz E, Yılmaz Ö, Olivares AZ, et al. Rapid identification of . J Pathol Clin Res. 2016;3(1):29-37doi: 10.1002/cjp2.57.
Demiray-Gürbüz, E., Yılmaz, �. �., Olivares, A. Z., Gönen, C., Sarıoğlu, S., Soytürk, M., Tümer, S., Altungöz, O., Şimşek, �. �., & Perez Perez, G. I. (2017). Rapid identification of . The journal of pathology. Clinical research, 3(1), 29-37. https://doi.org/10.1002/cjp2.57
Demiray-Gürbüz, Ebru, et al. "Rapid identification of ." The journal of pathology. Clinical research vol. 3,1 (2017): 29-37. doi: https://doi.org/10.1002/cjp2.57
Demiray-Gürbüz E, Yılmaz Ö, Olivares AZ, Gönen C, Sarıoğlu S, Soytürk M, Tümer S, Altungöz O, Şimşek İ, Perez Perez GI. Rapid identification of . J Pathol Clin Res. 2016 Nov 26;3(1):29-37. doi: 10.1002/cjp2.57. eCollection 2017 Jan. PMID: 28138399; PMCID: PMC5259560.
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Hydroxychloroquine Proves Ineffective in Hamsters and Macaques Infected with SARS-CoV-2.

bioRxiv : the preprint server for biology

Rosenke K, Jarvis MA, Feldmann F, Schwarz B, Okumura A, Lovaglio J, Saturday G, Hanley PW, Meade-White K, Williamson BN, Hansen F, Perez-Perez L, Leventhal S, Tang-Huau TL, Nason M, Callison J, Haddock E, Scott D, Sewell G, Bosio CM, Hawman D, de Wit E, Feldmann H.
PMID: 32577633
bioRxiv. 2020 Jun 11; doi: 10.1101/2020.06.10.145144.

We remain largely without effective prophylactic/therapeutic interventions for COVID-19. Although many human clinical trials are ongoing, there remains a deficiency of supportive preclinical drug efficacy studies. Here we assessed the prophylactic/therapeutic efficacy of hydroxychloroquine (HCQ), a drug of interest...

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Rosenke K, Jarvis MA, Feldmann F, et al. Hydroxychloroquine Proves Ineffective in Hamsters and Macaques Infected with SARS-CoV-2. bioRxiv. 2020;doi: 10.1101/2020.06.10.145144.
Rosenke, K., Jarvis, M. A., Feldmann, F., Schwarz, B., Okumura, A., Lovaglio, J., Saturday, G., Hanley, P. W., Meade-White, K., Williamson, B. N., Hansen, F., Perez-Perez, L., Leventhal, S., Tang-Huau, T. L., Nason, M., Callison, J., Haddock, E., Scott, D., Sewell, G., Bosio, C. M., Hawman, D., de Wit, E., & Feldmann, H. (2020). Hydroxychloroquine Proves Ineffective in Hamsters and Macaques Infected with SARS-CoV-2. bioRxiv : the preprint server for biology, . https://doi.org/10.1101/2020.06.10.145144
Rosenke, Kyle, et al. "Hydroxychloroquine Proves Ineffective in Hamsters and Macaques Infected with SARS-CoV-2." bioRxiv : the preprint server for biology vol. (2020). doi: https://doi.org/10.1101/2020.06.10.145144
Rosenke K, Jarvis MA, Feldmann F, Schwarz B, Okumura A, Lovaglio J, Saturday G, Hanley PW, Meade-White K, Williamson BN, Hansen F, Perez-Perez L, Leventhal S, Tang-Huau TL, Nason M, Callison J, Haddock E, Scott D, Sewell G, Bosio CM, Hawman D, de Wit E, Feldmann H. Hydroxychloroquine Proves Ineffective in Hamsters and Macaques Infected with SARS-CoV-2. bioRxiv. 2020 Jun 11; doi: 10.1101/2020.06.10.145144. PMID: 32577633; PMCID: PMC7301902.
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Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome.

medRxiv : the preprint server for health sciences

Sulaiman I, Chung M, Angel L, Tsay JJ, Wu BG, Yeung ST, Krolikowski K, Li Y, Duerr R, Schluger R, Thannickal SA, Koide A, Rafeq S, Barnett C, Postelnicu R, Wang C, Banakis S, Perez-Perez L, Jour G, Shen G, Meyn P, Carpenito J, Liu X, Ji K, Collazo D, Labarbiera A, Amoroso N, Brosnahan S, Mukherjee V, Kaufman D, Bakker J, Lubinsky A, Pradhan D, Sterman DH, Weiden M, Hegu A, Evans L, Uyeki TM, Clemente JC, De Wit E, Schmidt AM, Shopsin B, Desvignes L, Wang C, Li H, Zhang B, Forst CV, Koide S, Stapleford KA, Khanna KM, Ghedin E, Segal LN.
PMID: 33655261
medRxiv. 2021 Feb 26; doi: 10.1101/2021.02.23.21252221.

Mortality among patients with COVID-19 and respiratory failure is high and there are no known lower airway biomarkers that predict clinical outcome. We investigated whether bacterial respiratory infections and viral load were associated with poor clinical outcome and host...

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Sulaiman I, Chung M, Angel L, et al. Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome. medRxiv. 2021;doi: 10.1101/2021.02.23.21252221.
Sulaiman, I., Chung, M., Angel, L., Tsay, J. J., Wu, B. G., Yeung, S. T., Krolikowski, K., Li, Y., Duerr, R., Schluger, R., Thannickal, S. A., Koide, A., Rafeq, S., Barnett, C., Postelnicu, R., Wang, C., Banakis, S., Perez-Perez, L., Jour, G., Shen, G., Meyn, P., Carpenito, J., Liu, X., Ji, K., Collazo, D., Labarbiera, A., Amoroso, N., Brosnahan, S., Mukherjee, V., Kaufman, D., Bakker, J., Lubinsky, A., Pradhan, D., Sterman, D. H., Weiden, M., Hegu, A., Evans, L., Uyeki, T. M., Clemente, J. C., De Wit, E., Schmidt, A. M., Shopsin, B., Desvignes, L., Wang, C., Li, H., Zhang, B., Forst, C. V., Koide, S., Stapleford, K. A., Khanna, K. M., Ghedin, E., & Segal, L. N. (2021). Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome. medRxiv : the preprint server for health sciences, . https://doi.org/10.1101/2021.02.23.21252221
Sulaiman, Imran, et al. "Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome." medRxiv : the preprint server for health sciences vol. (2021). doi: https://doi.org/10.1101/2021.02.23.21252221
Sulaiman I, Chung M, Angel L, Tsay JJ, Wu BG, Yeung ST, Krolikowski K, Li Y, Duerr R, Schluger R, Thannickal SA, Koide A, Rafeq S, Barnett C, Postelnicu R, Wang C, Banakis S, Perez-Perez L, Jour G, Shen G, Meyn P, Carpenito J, Liu X, Ji K, Collazo D, Labarbiera A, Amoroso N, Brosnahan S, Mukherjee V, Kaufman D, Bakker J, Lubinsky A, Pradhan D, Sterman DH, Weiden M, Hegu A, Evans L, Uyeki TM, Clemente JC, De Wit E, Schmidt AM, Shopsin B, Desvignes L, Wang C, Li H, Zhang B, Forst CV, Koide S, Stapleford KA, Khanna KM, Ghedin E, Segal LN. Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome. medRxiv. 2021 Feb 26; doi: 10.1101/2021.02.23.21252221. PMID: 33655261; PMCID: PMC7924286.
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Subcutaneous REGEN-COV Antibody Combination in Early SARS-CoV-2 Infection.

medRxiv : the preprint server for health sciences

O'Brien MP, Forleo-Neto E, Sarkar N, Isa F, Hou P, Chan KC, Musser BJ, Bar KJ, Barnabas RV, Barouch DH, Cohen MS, Hurt CB, Burwen DR, Marovich MA, Heirman I, Davis JD, Turner KC, Ramesh D, Mahmood A, Hooper AT, Hamilton JD, Kim Y, Purcell LA, Baum A, Kyratsous CA, Krainson J, Perez-Perez R, Mohseni R, Kowal B, DiCioccio AT, Stahl N, Lipsich L, Braunstein N, Herman G, Yancopoulos GD, Weinreich DM.
PMID: 34159343
medRxiv. 2021 Jun 14; doi: 10.1101/2021.06.14.21258569.

BACKGROUND: Casirivimab and imdevimab administered together (REGEN-COV™) markedly reduces the risk of hospitalization or death in high-risk, symptomatic individuals with COVID-19. Here, we report phase 3 results of early treatment of asymptomatic, SARS-CoV-2-positive adults and adolescents with subcutaneous REGEN-COV.METHODS:...

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O'Brien MP, Forleo-Neto E, Sarkar N, et al. Subcutaneous REGEN-COV Antibody Combination in Early SARS-CoV-2 Infection. medRxiv. 2021;doi: 10.1101/2021.06.14.21258569.
O'Brien, M. P., Forleo-Neto, E., Sarkar, N., Isa, F., Hou, P., Chan, K. C., Musser, B. J., Bar, K. J., Barnabas, R. V., Barouch, D. H., Cohen, M. S., Hurt, C. B., Burwen, D. R., Marovich, M. A., Heirman, I., Davis, J. D., Turner, K. C., Ramesh, D., Mahmood, A., Hooper, A. T., Hamilton, J. D., Kim, Y., Purcell, L. A., Baum, A., Kyratsous, C. A., Krainson, J., Perez-Perez, R., Mohseni, R., Kowal, B., DiCioccio, A. T., Stahl, N., Lipsich, L., Braunstein, N., Herman, G., Yancopoulos, G. D., & Weinreich, D. M. (2021). Subcutaneous REGEN-COV Antibody Combination in Early SARS-CoV-2 Infection. medRxiv : the preprint server for health sciences, . https://doi.org/10.1101/2021.06.14.21258569
O'Brien, Meagan P, et al. "Subcutaneous REGEN-COV Antibody Combination in Early SARS-CoV-2 Infection." medRxiv : the preprint server for health sciences vol. (2021). doi: https://doi.org/10.1101/2021.06.14.21258569
O'Brien MP, Forleo-Neto E, Sarkar N, Isa F, Hou P, Chan KC, Musser BJ, Bar KJ, Barnabas RV, Barouch DH, Cohen MS, Hurt CB, Burwen DR, Marovich MA, Heirman I, Davis JD, Turner KC, Ramesh D, Mahmood A, Hooper AT, Hamilton JD, Kim Y, Purcell LA, Baum A, Kyratsous CA, Krainson J, Perez-Perez R, Mohseni R, Kowal B, DiCioccio AT, Stahl N, Lipsich L, Braunstein N, Herman G, Yancopoulos GD, Weinreich DM. Subcutaneous REGEN-COV Antibody Combination in Early SARS-CoV-2 Infection. medRxiv. 2021 Jun 14; doi: 10.1101/2021.06.14.21258569. PMID: 34159343; PMCID: PMC8219113.
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Arithmetic Word-Problem Solving as Cognitive Marker of Progression in Pre-Manifest and Manifest Huntington's Disease.

Journal of Huntington's disease

Horta-Barba A, Martinez-Horta S, Perez-Perez J, Sampedro F, de Lucia N, De Michele G, Salvatore E, Kehrer S, Priller J, Migliore S, Squitieri F, Castaldo A, Mariotti C, Mañanes V, Lopez-Sendon JL, Rodriguez N, Martinez-Descals A, Júlio F, Janurio C, Delussi M, de Tommaso M, Noguera S, Ruiz-Idiago J, Sitek EJ, Wallner R, Nuzzi A, Pagonabarraga J, Kulisevsky J.
PMID: 34602494
J Huntingtons Dis. 2021;10(4):459-468. doi: 10.3233/JHD-210480.

BACKGROUND: Arithmetic word-problem solving depends on the interaction of several cognitive processes that may be affected early in the disease in gene-mutation carriers for Huntington's disease (HD).OBJECTIVE: Our goal was to examine the pattern of performance of arithmetic tasks...

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Horta-Barba A, Martinez-Horta S, Perez-Perez J, et al. Arithmetic Word-Problem Solving as Cognitive Marker of Progression in Pre-Manifest and Manifest Huntington's Disease. J Huntingtons Dis. 2021;10(4):459-468doi: 10.3233/JHD-210480.
Horta-Barba, A., Martinez-Horta, S., Perez-Perez, J., Sampedro, F., de Lucia, N., De Michele, G., Salvatore, E., Kehrer, S., Priller, J., Migliore, S., Squitieri, F., Castaldo, A., Mariotti, C., Mañanes, V., Lopez-Sendon, J. L., Rodriguez, N., Martinez-Descals, A., Júlio, F., Janurio, C., Delussi, M., de Tommaso, M., Noguera, S., Ruiz-Idiago, J., Sitek, E. J., Wallner, R., Nuzzi, A., Pagonabarraga, J., Kulisevsky, J. (2021). Arithmetic Word-Problem Solving as Cognitive Marker of Progression in Pre-Manifest and Manifest Huntington's Disease. Journal of Huntington's disease, 10(4), 459-468. https://doi.org/10.3233/JHD-210480
Horta-Barba, Andrea, et al. "Arithmetic Word-Problem Solving as Cognitive Marker of Progression in Pre-Manifest and Manifest Huntington's Disease." Journal of Huntington's disease vol. 10,4 (2021): 459-468. doi: https://doi.org/10.3233/JHD-210480
Horta-Barba A, Martinez-Horta S, Perez-Perez J, Sampedro F, de Lucia N, De Michele G, Salvatore E, Kehrer S, Priller J, Migliore S, Squitieri F, Castaldo A, Mariotti C, Mañanes V, Lopez-Sendon JL, Rodriguez N, Martinez-Descals A, Júlio F, Janurio C, Delussi M, de Tommaso M, Noguera S, Ruiz-Idiago J, Sitek EJ, Wallner R, Nuzzi A, Pagonabarraga J, Kulisevsky J. Arithmetic Word-Problem Solving as Cognitive Marker of Progression in Pre-Manifest and Manifest Huntington's Disease. J Huntingtons Dis. 2021;10(4):459-468. doi: 10.3233/JHD-210480. PMID: 34602494.
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The Small Metal-Binding Protein SmbP Simplifies the Recombinant Expression and Purification of the Antimicrobial Peptide LL-37.

Antibiotics (Basel, Switzerland)

Perez-Perez DA, Villanueva-Ramirez TJ, Hernandez-Pedraza AE, Casillas-Vega NG, Gonzalez-Barranco P, Zarate X.
PMID: 34680851
Antibiotics (Basel). 2021 Oct 19;10(10). doi: 10.3390/antibiotics10101271.

(1) Background: The cathelicidin peptide LL-37 is a prominent molecule with many biological activities, including antimicrobial. Due to its importance, here, we describe the production of LL-37 tagged with SmbP, a relatively new carrier protein that improves the production...

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Perez-Perez DA, Villanueva-Ramirez TJ, Hernandez-Pedraza AE, et al. The Small Metal-Binding Protein SmbP Simplifies the Recombinant Expression and Purification of the Antimicrobial Peptide LL-37. Antibiotics (Basel). 2021;10(10)doi: 10.3390/antibiotics10101271.
Perez-Perez, D. A., Villanueva-Ramirez, T. J., Hernandez-Pedraza, A. E., Casillas-Vega, N. G., Gonzalez-Barranco, P., & Zarate, X. (2021). The Small Metal-Binding Protein SmbP Simplifies the Recombinant Expression and Purification of the Antimicrobial Peptide LL-37. Antibiotics (Basel, Switzerland), 10(10), . https://doi.org/10.3390/antibiotics10101271
Perez-Perez, David A, et al. "The Small Metal-Binding Protein SmbP Simplifies the Recombinant Expression and Purification of the Antimicrobial Peptide LL-37." Antibiotics (Basel, Switzerland) vol. 10,10 (2021). doi: https://doi.org/10.3390/antibiotics10101271
Perez-Perez DA, Villanueva-Ramirez TJ, Hernandez-Pedraza AE, Casillas-Vega NG, Gonzalez-Barranco P, Zarate X. The Small Metal-Binding Protein SmbP Simplifies the Recombinant Expression and Purification of the Antimicrobial Peptide LL-37. Antibiotics (Basel). 2021 Oct 19;10(10). doi: 10.3390/antibiotics10101271. PMID: 34680851; PMCID: PMC8532731.
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Subcutaneous REGEN-COV Antibody Combination in Early Asymptomatic SARS-CoV-2 Infection: A Randomized Clinical Trial.

medRxiv : the preprint server for health sciences

O'Brien MP, Forleo-Neto E, Sarkar N, Isa F, Hou P, Chan KC, Musser BJ, Bar KJ, Barnabas RV, Barouch DH, Cohen MS, Hurt CB, Burwen DR, Marovich MA, Brown ER, Heirman I, Davis JD, Turner KC, Ramesh D, Mahmood A, Hooper AT, Hamilton JD, Kim Y, Purcell LA, Baum A, Kyratsous CA, Krainson J, Perez-Perez R, Mohseni R, Kowal B, DiCioccio AT, Stahl N, Lipsich L, Braunstein N, Herman G, Yancopoulos GD, Weinreich DM.
PMID: 34159343
medRxiv. 2021 Sep 18; doi: 10.1101/2021.06.14.21258569.

IMPORTANCE: Easy-to-administer antiviral treatments may be used to prevent progression from asymptomatic infection to COVID-19 and to reduce viral carriage.OBJECTIVE: Evaluate the efficacy and safety of subcutaneous casirivimab and imdevimab antibody combination (REGEN-COV) to prevent progression from early asymptomatic...

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O'Brien MP, Forleo-Neto E, Sarkar N, et al. Subcutaneous REGEN-COV Antibody Combination in Early Asymptomatic SARS-CoV-2 Infection: A Randomized Clinical Trial. medRxiv. 2021;doi: 10.1101/2021.06.14.21258569.
O'Brien, M. P., Forleo-Neto, E., Sarkar, N., Isa, F., Hou, P., Chan, K. C., Musser, B. J., Bar, K. J., Barnabas, R. V., Barouch, D. H., Cohen, M. S., Hurt, C. B., Burwen, D. R., Marovich, M. A., Brown, E. R., Heirman, I., Davis, J. D., Turner, K. C., Ramesh, D., Mahmood, A., Hooper, A. T., Hamilton, J. D., Kim, Y., Purcell, L. A., Baum, A., Kyratsous, C. A., Krainson, J., Perez-Perez, R., Mohseni, R., Kowal, B., DiCioccio, A. T., Stahl, N., Lipsich, L., Braunstein, N., Herman, G., Yancopoulos, G. D., Weinreich, D. M. (2021). Subcutaneous REGEN-COV Antibody Combination in Early Asymptomatic SARS-CoV-2 Infection: A Randomized Clinical Trial. medRxiv : the preprint server for health sciences, . https://doi.org/10.1101/2021.06.14.21258569
O'Brien, Meagan P, et al. "Subcutaneous REGEN-COV Antibody Combination in Early Asymptomatic SARS-CoV-2 Infection: A Randomized Clinical Trial." medRxiv : the preprint server for health sciences vol. (2021). doi: https://doi.org/10.1101/2021.06.14.21258569
O'Brien MP, Forleo-Neto E, Sarkar N, Isa F, Hou P, Chan KC, Musser BJ, Bar KJ, Barnabas RV, Barouch DH, Cohen MS, Hurt CB, Burwen DR, Marovich MA, Brown ER, Heirman I, Davis JD, Turner KC, Ramesh D, Mahmood A, Hooper AT, Hamilton JD, Kim Y, Purcell LA, Baum A, Kyratsous CA, Krainson J, Perez-Perez R, Mohseni R, Kowal B, DiCioccio AT, Stahl N, Lipsich L, Braunstein N, Herman G, Yancopoulos GD, Weinreich DM. Subcutaneous REGEN-COV Antibody Combination in Early Asymptomatic SARS-CoV-2 Infection: A Randomized Clinical Trial. medRxiv. 2021 Sep 18; doi: 10.1101/2021.06.14.21258569. PMID: 34159343; PMCID: PMC8219113.
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Effect of antibiotic pre-treatment and pathogen challenge on the intestinal microbiota in mice.

Gut pathogens

Iizumi T, Taniguchi T, Yamazaki W, Vilmen G, Alekseyenko AV, Gao Z, Perez Perez GI, Blaser MJ.
PMID: 27891184
Gut Pathog. 2016 Nov 18;8:60. doi: 10.1186/s13099-016-0143-z. eCollection 2016.

BACKGROUND: More than 50 years after the discovery of antibiotics, bacterial infections have decreased substantially; however, antibiotics also may have negative effects such as increasing susceptibility to pathogens. An intact microbiome is an important line of defense against pathogens....

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Iizumi T, Taniguchi T, Yamazaki W, et al. Effect of antibiotic pre-treatment and pathogen challenge on the intestinal microbiota in mice. Gut Pathog. 2016;8:60doi: 10.1186/s13099-016-0143-z.
Iizumi, T., Taniguchi, T., Yamazaki, W., Vilmen, G., Alekseyenko, A. V., Gao, Z., Perez Perez, G. I., & Blaser, M. J. (2016). Effect of antibiotic pre-treatment and pathogen challenge on the intestinal microbiota in mice. Gut pathogens, 860. https://doi.org/10.1186/s13099-016-0143-z
Iizumi, Tadasu, et al. "Effect of antibiotic pre-treatment and pathogen challenge on the intestinal microbiota in mice." Gut pathogens vol. 8 (2016): 60. doi: https://doi.org/10.1186/s13099-016-0143-z
Iizumi T, Taniguchi T, Yamazaki W, Vilmen G, Alekseyenko AV, Gao Z, Perez Perez GI, Blaser MJ. Effect of antibiotic pre-treatment and pathogen challenge on the intestinal microbiota in mice. Gut Pathog. 2016 Nov 18;8:60. doi: 10.1186/s13099-016-0143-z. eCollection 2016. PMID: 27891184; PMCID: PMC5116224.
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Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome.

Research square

Sulaiman I, Chung M, Angel L, Koralov S, Wu B, Yeung S, Krolikowski K, Li Y, Duerr R, Schluger R, Thannickal S, Koide A, Rafeq S, Barnett C, Postelnicu R, Wang C, Banakis S, Perez-Perez L, Jour G, Shen G, Meyn P, Carpenito J, Liu X, Ji K, Collazo D, Labarbiera A, Amoroso N, Brosnahan S, Mukherjee V, Kaufman D, Bakker J, Lubinsky A, Pradhan D, Sterman D, Heguy A, Uyeki T, Clemente J, de Wit E, Schmidt AM, Shopsin B, Desvignes L, Wang C, Li H, Zhang B, Forst C, Koide S, Stapleford K, Khanna K, Ghedin E, Weiden M, Segal L.
PMID: 33791687
Res Sq. 2021 Mar 29; doi: 10.21203/rs.3.rs-266050/v1.

Mortality among patients with COVID-19 and respiratory failure is high and there are no known lower airway biomarkers that predict clinical outcome. We investigated whether bacterial respiratory infections and viral load were associated with poor clinical outcome and host...

Cite
Sulaiman I, Chung M, Angel L, et al. Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome. Res Sq. 2021;doi: 10.21203/rs.3.rs-266050/v1.
Sulaiman, I., Chung, M., Angel, L., Koralov, S., Wu, B., Yeung, S., Krolikowski, K., Li, Y., Duerr, R., Schluger, R., Thannickal, S., Koide, A., Rafeq, S., Barnett, C., Postelnicu, R., Wang, C., Banakis, S., Perez-Perez, L., Jour, G., Shen, G., Meyn, P., Carpenito, J., Liu, X., Ji, K., Collazo, D., Labarbiera, A., Amoroso, N., Brosnahan, S., Mukherjee, V., Kaufman, D., Bakker, J., Lubinsky, A., Pradhan, D., Sterman, D., Heguy, A., Uyeki, T., Clemente, J., de Wit, E., Schmidt, A. M., Shopsin, B., Desvignes, L., Wang, C., Li, H., Zhang, B., Forst, C., Koide, S., Stapleford, K., Khanna, K., Ghedin, E., Weiden, M., & Segal, L. (2021). Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome. Research square, . https://doi.org/10.21203/rs.3.rs-266050/v1
Sulaiman, Imran, et al. "Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome." Research square vol. (2021). doi: https://doi.org/10.21203/rs.3.rs-266050/v1
Sulaiman I, Chung M, Angel L, Koralov S, Wu B, Yeung S, Krolikowski K, Li Y, Duerr R, Schluger R, Thannickal S, Koide A, Rafeq S, Barnett C, Postelnicu R, Wang C, Banakis S, Perez-Perez L, Jour G, Shen G, Meyn P, Carpenito J, Liu X, Ji K, Collazo D, Labarbiera A, Amoroso N, Brosnahan S, Mukherjee V, Kaufman D, Bakker J, Lubinsky A, Pradhan D, Sterman D, Heguy A, Uyeki T, Clemente J, de Wit E, Schmidt AM, Shopsin B, Desvignes L, Wang C, Li H, Zhang B, Forst C, Koide S, Stapleford K, Khanna K, Ghedin E, Weiden M, Segal L. Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome. Res Sq. 2021 Mar 29; doi: 10.21203/rs.3.rs-266050/v1. PMID: 33791687; PMCID: PMC8010736.
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Diabetes mellitus and cardiovascular disease.

European journal of internal medicine

Wagner AM, Martijnez-Rubio A, Ordonez-Llanos J, Perez-Perez A.
PMID: 11836079
Eur J Intern Med. 2002 Feb;13(1):15-30. doi: 10.1016/s0953-6205(01)00194-7.

Diabetes is associated with a high incidence and poor prognosis of cardiovascular disease, and with high short- and long-term mortality. Adequate treatment of cardiovascular disorders and aggressive management of coexisting risk factors have proved to be at least as...

Cite
Wagner AM, Martijnez-Rubio A, Ordonez-Llanos J, et al. Diabetes mellitus and cardiovascular disease. Eur J Intern Med. 2002;13(1):15-30doi: 10.1016/s0953-6205(01)00194-7.
Wagner, A. M., Martijnez-Rubio, A., Ordonez-Llanos, J., & Perez-Perez, A. (2002). Diabetes mellitus and cardiovascular disease. European journal of internal medicine, 13(1), 15-30. https://doi.org/10.1016/s0953-6205(01)00194-7
Wagner, A M., et al. "Diabetes mellitus and cardiovascular disease." European journal of internal medicine vol. 13,1 (2002): 15-30. doi: https://doi.org/10.1016/s0953-6205(01)00194-7
Wagner AM, Martijnez-Rubio A, Ordonez-Llanos J, Perez-Perez A. Diabetes mellitus and cardiovascular disease. Eur J Intern Med. 2002 Feb;13(1):15-30. doi: 10.1016/s0953-6205(01)00194-7. PMID: 11836079.
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