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Showing 1 to 12 of 24 entries
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Layered acoustofluidic resonators for the simultaneous optical and acoustic characterisation of cavitation dynamics, microstreaming, and biological effects.

Biomicrofluidics

Pereno V, Aron M, Vince O, Mannaris C, Seth A, de Saint Victor M, Lajoinie G, Versluis M, Coussios C, Carugo D, Stride E.
PMID: 29887932
Biomicrofluidics. 2018 May 30;12(3):034109. doi: 10.1063/1.5023729. eCollection 2018 May.

The study of the effects of ultrasound-induced acoustic cavitation on biological structures is an active field in biomedical research. Of particular interest for therapeutic applications is the ability of oscillating microbubbles to promote both cellular and tissue membrane permeabilisation...

Chronically elevated branched chain amino acid levels are pro-arrhythmic.

Cardiovascular research

Portero V, Nicol T, Podliesna S, Marchal GA, Baartscheer A, Casini S, Tadros R, Treur JL, Tanck MWT, Cox IJ, Probert F, Hough TA, Falcone S, Beekman L, Müller-Nurasyid M, Kastenmüller G, Gieger C, Peters A, Kääb S, Sinner MF, Blease A, Verkerk AO, Bezzina CR, Potter PK, Remme CA.
PMID: 34142125
Cardiovasc Res. 2021 Jun 17; doi: 10.1093/cvr/cvab207. Epub 2021 Jun 17.

AIM: Cardiac arrhythmias comprise a major health and economic burden and are associated with significant morbidity and mortality, including cardiac failure, stroke and sudden cardiac death (SCD). Development of efficient preventive and therapeutic strategies is hampered by incomplete knowledge...

A Multicenter Analysis of the Outcome of Cancer Patients with Neutropenia and COVID-19 Optionally Treated with Granulocyte-Colony Stimulating Factor (G-CSF): A Comparative Analysis.

Cancers

Sereno M, Jimenez-Gordo AM, Baena-Espinar J, Aguado C, Mielgo X, Pertejo A, Álvarez-Álvarez R, Sánchez A, López JL, Molina R, López-Alfonso A, Hernández B, Chiara LE, Martín AM, López-Martín A, Dorta M, Collazo-Lorduy A, Casado E, de Molina AR, Colmenarejo G.
PMID: 34439359
Cancers (Basel). 2021 Aug 20;13(16). doi: 10.3390/cancers13164205.

BACKGROUND: Approximately 15% of patients infected by SARS-CoV-2 develop a distress syndrome secondary to a host hyperinflammatory response induced by a cytokine storm. Myelosuppression is associated with a higher risk of infections and mortality. There are data to support...

Targeting the Microtubule EB1-CLASP2 Complex Modulates Na.

Circulation research

Marchal GA, Jouni M, Chiang DY, Pérez-Hernández M, Podliesna S, Yu N, Casini S, Potet F, Veerman CC, Klerk M, Lodder EM, Mengarelli I, Guan K, Vanoye CG, Rothenberg E, Charpentier F, Redon R, George AL, Verkerk AO, Bezzina CR, MacRae CA, Burridge PW, Delmar M, Galjart N, Portero V, Remme CA.
PMID: 34092082
Circ Res. 2021 Jul 23;129(3):349-365. doi: 10.1161/CIRCRESAHA.120.318643. Epub 2021 Jun 07.

[Figure: see text].

Publisher's Note: "Coherence imaging spectroscopy at Wendelstein 7-X for impurity flow measurements" [Rev. Sci. Instrum. 91, 013501 (2020)].

The Review of scientific instruments

Perseo V, Gradic D, König R, Ford OP, Killer C, Grulke O, Ennis DA.
PMID: 32113401
Rev Sci Instrum. 2020 Feb 01;91(2):029901. doi: 10.1063/1.5145122.

No abstract available.

The degree of abstraction in solving addition and subtraction problems.

The Spanish journal of psychology

Bermejo V, Díaz JJ.
PMID: 17992955
Span J Psychol. 2007 Nov;10(2):285-93. doi: 10.1017/s1138741600006557.

In this study, the incidence of the degree of abstraction in solving addition and subtraction problems with the unknown in the first term and in the result is analyzed. Ninety-six students from first grade to fourth grade in Primary...

Novel pyrrolobenzodiazepine and pyrroloquinazoline scaffolds synthesized by a simple and highly selective Ugi/cyclization sequence.

Organic & biomolecular chemistry

Pertejo P, Peña-Calleja P, Carreira-Barral I, Quesada R, Alejandro Cordero N, Javier Rodríguez F, García-Valverde M.
PMID: 28853757
Org Biomol Chem. 2017 Sep 20;15(36):7549-7557. doi: 10.1039/c7ob01807j.

Pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) and other benzo-fused N-heterocycles constitute privileged structures found in numerous bioactive compounds. Thus, developing simple and selective syntheses to furnish these derivatives from easily accessible starting materials is an important and challenging goal. In this work, novel...

Post-Ugi Transformations for the Access to Pyrrolobenzodiazepine Scaffolds with Different Degrees of Unsaturation.

The Journal of organic chemistry

Pertejo P, Carreira-Barral I, Peña-Calleja P, Quesada R, García-Valverde M.
PMID: 31927929
J Org Chem. 2020 Feb 21;85(4):2291-2302. doi: 10.1021/acs.joc.9b02995. Epub 2020 Jan 22.

The synthesis of three novel families of pyrrolo[2,1-

The Role of PEG-40-stearate in the Production, Morphology, and Stability of Microbubbles.

Langmuir : the ACS journal of surfaces and colloids

Owen J, Kamila S, Shrivastava S, Carugo D, Bernardino de la Serna J, Mannaris C, Pereno V, Browning R, Beguin E, McHale AP, Callan JF, Stride E.
PMID: 30485112
Langmuir. 2019 Aug 06;35(31):10014-10024. doi: 10.1021/acs.langmuir.8b02516. Epub 2018 Dec 10.

Phospholipid coated microbubbles are currently in widespread clinical use as ultrasound contrast agents and under investigation for therapeutic applications. Previous studies have demonstrated the importance of the coating nanostructure in determining microbubble stability and its dependence upon both composition...

One-Pot Synthesis of Enantiopure Pyrrolopiperazines.

The Journal of organic chemistry

Pertejo P, González-Saiz B, Quesada R, García-Valverde M.
PMID: 33052681
J Org Chem. 2020 Nov 06;85(21):14240-14245. doi: 10.1021/acs.joc.0c02103. Epub 2020 Oct 14.

A simple one-pot protocol for the synthesis of fused pyrrolopiperazines with a complete diastereoselectivity has been developed. This novel methodology combined the Ugi reaction with a spontaneous enamine alkylation on a multicomponent domino reaction, starting from nonprotected diamines and...

Targeting the Microtubule EB1-CLASP2 Complex Modulates Na.

Circulation research

Marchal GA, Jouni M, Chiang DY, Pérez-Hernández M, Podliesna S, Yu N, Casini S, Potet F, Veerman CC, Klerk M, Lodder EM, Mengarelli I, Guan K, Vanoye CG, Rothenberg E, Charpentier F, Redon R, George AL, Verkerk AO, Bezzina CR, MacRae CA, Burridge PW, Delmar M, Galjart N, Portero V, Remme CA.
PMID: 34092082
Circ Res. 2021 Jul 23;129(3):349-365. doi: 10.1161/CIRCRESAHA.120.318643. Epub 2021 Jun 07.

[Figure: see text].

Performance of the prototype LaBr.

The Review of scientific instruments

Rigamonti D, Muraro A, Nocente M, Perseo V, Boltruczyk G, Fernandes A, Figueiredo J, Giacomelli L, Gorini G, Gosk M, Kiptily V, Korolczuk S, Mianowski S, Murari A, Pereira RC, Cippo EP, Zychor I, Tardocchi M.
PMID: 27910639
Rev Sci Instrum. 2016 Nov;87(11):11E717. doi: 10.1063/1.4961060.

In this work, we describe the solution developed by the gamma ray camera upgrade enhancement project to improve the spectroscopic properties of the existing JET γ-ray camera. Aim of the project is to enable gamma-ray spectroscopy in JET deuterium-tritium...

Showing 1 to 12 of 24 entries