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Population pharmacodynamic and pharmacokinetic modeling via mixed effects.

Current opinion in drug discovery & development

Piotrovsky VK.
PMID: 19649865
Curr Opin Drug Discov Devel. 2000 May;3(3):314-30.

Pharmacokinetics (PK) and pharmacodynamics (PD) are two scientific disciplines forming the basis of modern pharmaco- and chemotherapy. PK reflects what the body does to drugs and primarily deals with plasma concentration of drugs, whereas PD reflects what drugs do...

Model-independent definition of the initial volume of distribution of drugs in the body.

International journal of clinical pharmacology, therapy, and toxicology

Piotrovskii VK.
PMID: 3759276
Int J Clin Pharmacol Ther Toxicol. 1986 Aug;24(8):403-7.

Model-independent definition of the initial volume of distribution of drugs in the body as a limit of the ratio of the drug content in the body to its blood concentration with time from the start of drug administration tending...

Showing 1 to 2 of 2 entries