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Showing 1 to 12 of 17 entries
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Why and how to evaluate driving abilities in patients with neurodegenerative diseases?.

Geriatrie et psychologie neuropsychiatrie du vieillissement

Lazeras C, Cartier M, Bonnet M, Laurens B, Meissner WG, Planche V.
PMID: 34753708
Geriatr Psychol Neuropsychiatr Vieil. 2021 Nov 09; doi: 10.1684/pnv.2021.0975. Epub 2021 Nov 09.

Many studies have shown that individuals with neurodegenerative diseases are at risk of being involved in a traffic accident. However, driving is critical for social integration and independence in daily life. The lack of consensus and a standardised assessment...

Clinical and prognostic significance of antinuclear antibodies in primary antiphospholipid syndrome: A multicenter retrospective study.

Joint bone spine

Ricard L, Laurent C, Papo M, Deriaz S, Catano J, Alamowitch S, Kayem G, Chasset F, De Moreuil C, Boffa JJ, Gerotziafas G, Elalamy I, Bornes M, Maillot F, Audemard-Verger A, Planche V, Ballot E, Fain O, Mekinian A.
PMID: 34656751
Joint Bone Spine. 2021 Oct 14;89(2):105297. doi: 10.1016/j.jbspin.2021.105297. Epub 2021 Oct 14.

INTRODUCTION: The antiphospholipid syndrome (APS) (1) is defined by the development of vascular thrombosis, or pregnancy morbidity in the presence of persistent antiphospholipid antibodies (aPL). Antinuclear antibodies (ANA) can be detected in primary APS patients without any clinical systemic...

Distinct Hippocampal Subfields Atrophy in Older People With Vascular Brain Injuries.

Stroke

Pin G, Coupé P, Nadal L, Manjon JV, Helmer C, Amieva H, Mazoyer B, Dartigues JF, Catheline G, Planche V.
PMID: 33657856
Stroke. 2021 May;52(5):1741-1750. doi: 10.1161/STROKEAHA.120.031743. Epub 2021 Mar 04.

BACKGROUND AND PURPOSE: Many neurological or psychiatric diseases affect the hippocampus during aging. The study of hippocampal regional vulnerability may provide important insights into the pathophysiological mechanisms underlying these processes; however, little is known about the specific impact of...

Differential Gray Matter Vulnerability in the 1 Year Following a Clinically Isolated Syndrome.

Frontiers in neurology

Koubiyr I, Deloire M, Coupé P, Dulau C, Besson P, Moroso A, Planche V, Tourdias T, Brochet B, Ruet A.
PMID: 30364223
Front Neurol. 2018 Oct 11;9:824. doi: 10.3389/fneur.2018.00824. eCollection 2018.

No abstract available.

Clinical and prognostic significance of antinuclear antibodies in primary antiphospholipid syndrome: A multicenter retrospective study.

Joint bone spine

Ricard L, Laurent C, Papo M, Deriaz S, Catano J, Alamowitch S, Kayem G, Chasset F, De Moreuil C, Boffa JJ, Gerotziafas G, Elalamy I, Bornes M, Maillot F, Audemard-Verger A, Planche V, Ballot E, Fain O, Mekinian A.
PMID: 34656751
Joint Bone Spine. 2021 Oct 14;89(2):105297. doi: 10.1016/j.jbspin.2021.105297. Epub 2021 Oct 14.

INTRODUCTION: The antiphospholipid syndrome (APS) (1) is defined by the development of vascular thrombosis, or pregnancy morbidity in the presence of persistent antiphospholipid antibodies (aPL). Antinuclear antibodies (ANA) can be detected in primary APS patients without any clinical systemic...

US Food and Drug Administration Approval of Aducanumab-Is Amyloid Load a Valid Surrogate End Point for Alzheimer Disease Clinical Trials?.

JAMA neurology

Planche V, Villain N.
PMID: 34515750
JAMA Neurol. 2021 Nov 01;78(11):1307-1308. doi: 10.1001/jamaneurol.2021.3126.

No abstract available.

Lack of limbic-predominant age-related TDP-43 encephalopathy (LATE) neuropathological changes in aged macaques with memory impairment.

Neurobiology of aging

Darricau M, Canron MH, Bosc M, Arotçarena ML, Quang ML, Dehay B, Bezard E, Planche V.
PMID: 34384992
Neurobiol Aging. 2021 Nov;107:53-56. doi: 10.1016/j.neurobiolaging.2021.07.009. Epub 2021 Jul 21.

The neuropathological changes of limbic-predominant age-related TDP-43 encephalopathy (LATE) are frequent in the aged population and are now recognized as a cause of memory impairment. However, it remains unknown if this proteinopathy is also present in other primate species....

Complement C3 mediates early hippocampal neurodegeneration and memory impairment in experimental multiple sclerosis.

Neurobiology of disease

Bourel J, Planche V, Dubourdieu N, Oliveira A, Séré A, Ducourneau EG, Tible M, Maitre M, Lesté-Lasserre T, Nadjar A, Desmedt A, Ciofi P, Oliet SH, Panatier A, Tourdias T.
PMID: 34673149
Neurobiol Dis. 2021 Dec;160:105533. doi: 10.1016/j.nbd.2021.105533. Epub 2021 Oct 19.

Memory impairment is one of the disabling manifestations of multiple sclerosis (MS) possibly present from the early stages of the disease and for which there is no specific treatment. Hippocampal synaptic dysfunction and dendritic loss, associated with microglial activation,...

Clinical and prognostic significance of antinuclear antibodies in primary antiphospholipid syndrome: A multicenter retrospective study.

Joint bone spine

Ricard L, Laurent C, Papo M, Deriaz S, Catano J, Alamowitch S, Kayem G, Chasset F, De Moreuil C, Boffa JJ, Gerotziafas G, Elalamy I, Bornes M, Maillot F, Audemard-Verger A, Planche V, Ballot E, Fain O, Mekinian A.
PMID: 34656751
Joint Bone Spine. 2021 Oct 14;89(2):105297. doi: 10.1016/j.jbspin.2021.105297. Epub 2021 Oct 14.

INTRODUCTION: The antiphospholipid syndrome (APS) (1) is defined by the development of vascular thrombosis, or pregnancy morbidity in the presence of persistent antiphospholipid antibodies (aPL). Antinuclear antibodies (ANA) can be detected in primary APS patients without any clinical systemic...

Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques.

Frontiers in bioengineering and biotechnology

Arotcarena ML, Dovero S, Biendon N, Dutheil N, Planche V, Bezard E, Dehay B.
PMID: 34869273
Front Bioeng Biotechnol. 2021 Nov 15;9:762209. doi: 10.3389/fbioe.2021.762209. eCollection 2021.

Adeno-associated virus (AAV) vectors are increasingly used as an effective and safe approach to deliver genetic material to the central nervous system (CNS). The AAV9-derived variants, AAV-PHP. B and AAV-PHP.eB, reportedly broadly transduce cells throughout the CNS compared to...

Lack of limbic-predominant age-related TDP-43 encephalopathy (LATE) neuropathological changes in aged macaques with memory impairment.

Neurobiology of aging

Darricau M, Canron MH, Bosc M, Arotçarena ML, Quang ML, Dehay B, Bezard E, Planche V.
PMID: 34384992
Neurobiol Aging. 2021 Nov;107:53-56. doi: 10.1016/j.neurobiolaging.2021.07.009. Epub 2021 Jul 21.

The neuropathological changes of limbic-predominant age-related TDP-43 encephalopathy (LATE) are frequent in the aged population and are now recognized as a cause of memory impairment. However, it remains unknown if this proteinopathy is also present in other primate species....

Clinical and prognostic significance of antinuclear antibodies in primary antiphospholipid syndrome: A multicenter retrospective study.

Joint bone spine

Ricard L, Laurent C, Papo M, Deriaz S, Catano J, Alamowitch S, Kayem G, Chasset F, De Moreuil C, Boffa JJ, Gerotziafas G, Elalamy I, Bornes M, Maillot F, Audemard-Verger A, Planche V, Ballot E, Fain O, Mekinian A.
PMID: 34656751
Joint Bone Spine. 2021 Oct 14;89(2):105297. doi: 10.1016/j.jbspin.2021.105297. Epub 2021 Oct 14.

INTRODUCTION: The antiphospholipid syndrome (APS) (1) is defined by the development of vascular thrombosis, or pregnancy morbidity in the presence of persistent antiphospholipid antibodies (aPL). Antinuclear antibodies (ANA) can be detected in primary APS patients without any clinical systemic...

Showing 1 to 12 of 17 entries