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Showing 1 to 12 of 21 entries
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On the Development of the SIMon Finite Element Head Model.

Stapp car crash journal

Takhounts EG, Eppinger RH, Campbell JQ, Tannous RE, Power ED, Shook LS.
PMID: 17096247
Stapp Car Crash J. 2003 Oct;47:107-33.

The SIMon (Simulated Injury Monitor) software package is being developed to advance the interpretation of injury mechanisms based on kinematic and kinetic data measured in the advanced anthropomorphic test dummy (AATD) and applying the measured dummy response to the...

Robotic Motion Compensation for Beating Heart Intracardiac Surgery.

The International journal of robotics research

Yuen SG, Kettler DT, Novotny PM, Plowes RD, Howe RD.
PMID: 20436927
Int J Rob Res. 2009 Oct 01;28(10):1355-1372. doi: 10.1177/0278364909104065.

3D ultrasound imaging has enabled minimally invasive, beating heart intracardiac procedures. However, rapid heart motion poses a serious challenge to the surgeon that is compounded by significant time delays and noise in 3D ultrasound. This paper investigates the concept...

Calculating Sample Size Requirements for Temporal Dynamics in Single-Cell Proteomics.

Molecular & cellular proteomics : MCP

Boekweg H, Guise AJ, Plowey ED, Kelly RT, Payne SH.
PMID: 33915259
Mol Cell Proteomics. 2021;20:100085. doi: 10.1016/j.mcpro.2021.100085. Epub 2021 Apr 27.

Single-cell measurements are uniquely capable of characterizing cell-to-cell heterogeneity and have been used to explore the large diversity of cell types and physiological functions present in tissues and other complex cell assemblies. An intriguing application of single-cell proteomics is...

Ultrasensitive single-cell proteomics workflow identifies >1000 protein groups per mammalian cell.

Chemical science

Cong Y, Motamedchaboki K, Misal SA, Liang Y, Guise AJ, Truong T, Huguet R, Plowey ED, Zhu Y, Lopez-Ferrer D, Kelly RT.
PMID: 34163866
Chem Sci. 2020 Nov 17;12(3):1001-1006. doi: 10.1039/d0sc03636f.

We report on the combination of nanodroplet sample preparation, ultra-low-flow nanoLC, high-field asymmetric ion mobility spectrometry (FAIMS), and the latest-generation Orbitrap Eclipse Tribrid mass spectrometer for greatly improved single-cell proteome profiling. FAIMS effectively filtered out singly charged ions for...

Structural characterization of KKT4, an unconventional microtubule-binding kinetochore protein.

Structure (London, England : 1993)

Ludzia P, Lowe ED, Marcianò G, Mohammed S, Redfield C, Akiyoshi B.
PMID: 33915106
Structure. 2021 Sep 02;29(9):1014-1028.e8. doi: 10.1016/j.str.2021.04.004. Epub 2021 Apr 28.

The kinetochore is the macromolecular machinery that drives chromosome segregation by interacting with spindle microtubules. Kinetoplastids (such as Trypanosoma brucei), a group of evolutionarily divergent eukaryotes, have a unique set of kinetochore proteins that lack any significant homology to...

Current Milestones Assessment Practices, Needs, and Challenges of Program Directors: A Collective Case Study in a Pediatric Hospital Setting.

Cureus

Lewis KO, Hathaway SB, Bratcher D, Blowey D, Knapp JF.
PMID: 33898152
Cureus. 2021 Apr 20;13(4):e14585. doi: 10.7759/cureus.14585.

Introduction Accreditation Council for Graduate Medical Education's (ACGME's) Milestones assessment requirement has placed new demands on Program Directors (PDs), especially those with limited knowledge of assessment and evaluation activities. There is a lack of clarity on how Program Director...

CCR2 deficiency alters activation of microglia subsets in traumatic brain injury.

Cell reports

Somebang K, Rudolph J, Imhof I, Li L, Niemi EC, Shigenaga J, Tran H, Gill TM, Lo I, Zabel BA, Schmajuk G, Wipke BT, Gyoneva S, Jandreski L, Craft M, Benedetto G, Plowey ED, Charo I, Campbell J, Ye CJ, Panter SS, Nakamura MC, Eckalbar W, Hsieh CL.
PMID: 34551293
Cell Rep. 2021 Sep 21;36(12):109727. doi: 10.1016/j.celrep.2021.109727.

In traumatic brain injury (TBI), a diversity of brain resident and peripherally derived myeloid cells have the potential to worsen damage and/or to assist in healing. We define the heterogeneity of microglia and macrophage phenotypes during TBI in wild-type...

Dermatologists for the nation: perspectives.

Archives of dermatology

Lowney ED.
PMID: 666339
Arch Dermatol. 1978 Jun;114(6):961-2.

No abstract available.

"Whatever I Have to Do That's Right:" Culture and the Precariousness of Personhood in a Poor Urban Neighborhood.

Ethos (Berkeley, Calif.)

Lowe ED.
PMID: 30416224
Ethos. 2018 Sep;46(3):311-329. doi: 10.1111/etho.12205. Epub 2018 Sep 04.

This article presents a person-centered case study of one woman's struggles to realize a meaningful sense of personhood in a low-income urban neighborhood in Milwaukee, Wisconsin. An analysis of longitudinal ethnographic data for this case reveals how everyday aspirations...

Calculating Sample Size Requirements for Temporal Dynamics in Single-Cell Proteomics.

Molecular & cellular proteomics : MCP

Boekweg H, Guise AJ, Plowey ED, Kelly RT, Payne SH.
PMID: 33915259
Mol Cell Proteomics. 2021 Apr 27;20:100085. doi: 10.1016/j.mcpro.2021.100085. Epub 2021 Apr 27.

Single-cell measurements are uniquely capable of characterizing cell-to-cell heterogeneity and have been used to explore the large diversity of cell types and physiological functions present in tissues and other complex cell assemblies. An intriguing application of single-cell proteomics is...

Features of Peptide Fragmentation Spectra in Single-Cell Proteomics.

Journal of proteome research

Boekweg H, Van Der Watt D, Truong T, Johnston SM, Guise AJ, Plowey ED, Kelly RT, Payne SH.
PMID: 34920664
J Proteome Res. 2022 Jan 07;21(1):182-188. doi: 10.1021/acs.jproteome.1c00670. Epub 2021 Dec 17.

The goal of proteomics is to identify and quantify the complete set of proteins in a biological sample. Single-cell proteomics specializes in the identification and quantitation of proteins for individual cells, often used to elucidate cellular heterogeneity. The significant...

Saliva Exhibits High Sensitivity and Specificity for the Detection of SARS-COV-2.

Diseases (Basel, Switzerland)

Warsi I, Khurshid Z, Shazam H, Umer MF, Imran E, Khan MO, Slowey PD, Goodson JM.
PMID: 34065171
Diseases. 2021 May 20;9(2). doi: 10.3390/diseases9020038.

In the wake of the COVID-19 pandemic, it is crucial to assess the application of a multitude of effective diagnostic specimens for conducting mass testing, for accurate diagnosis and to formulate strategies for its prevention and control. As one...

Showing 1 to 12 of 21 entries