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Showing 1 to 12 of 261 entries
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Aziridination of Cyclic Nitrones Targeting Constrained Iminosugars.

Organic letters

Tangara S, Aupic C, Kanazawa A, Poisson JF, Py S.
PMID: 28862453
Org Lett. 2017 Sep 15;19(18):4842-4845. doi: 10.1021/acs.orglett.7b02283. Epub 2017 Sep 01.

Rare C-7-substituted aziridinyl iminosugars can be synthesized through a short reaction sequence involving 1,3-cycloaddition of cyclic nitrones with alkynes and a Baldwin rearrangement of isoxazolines into bicyclic 2-acylaziridines. The method is efficient and completely diastereoselective, producing stable aziridinyl iminosugars...

Pd-Catalyzed Diastereoselective Trifluoromethylthiolation of Functionalized Acrylamides.

Organic letters

Zhao Q, Poisson T, Pannecoucke X, Bouillon JP, Besset T.
PMID: 28925266
Org Lett. 2017 Oct 06;19(19):5106-5109. doi: 10.1021/acs.orglett.7b02384. Epub 2017 Sep 19.

The Pd-catalyzed diastereoselective trifluoromethylthiolation of acrylamides was developed to allow the formation of the Z-isomer as a single product. Using a C-H bond functionalization strategy, the method was applied to a broad range of α-aryl, α-alkyl, and α,β-disubstituted acrylamides...

Tunable Approach for the Stereoselective Synthesis of 1-C-Diethylphosphono(difluoromethyl) Iminosugars as Glycosyl Phosphate Mimics.

The Journal of organic chemistry

Cocaud C, Nicolas C, Poisson T, Pannecoucke X, Legault CY, Martin OR.
PMID: 28221798
J Org Chem. 2017 Mar 03;82(5):2753-2763. doi: 10.1021/acs.joc.6b03071. Epub 2017 Feb 21.

An efficient methodology for the stereoselective and tunable addition of LiCF

Reactive and Inelastic Channels in the Ca*···FCH3 Transition State: A Simple Branching Mechanism.

The journal of physical chemistry. A

Briant M, Gloaguen E, Beswick A, Mestdagh JM, Stolte S, Poisson L, Pothier C, Soep B.
PMID: 25766058
J Phys Chem A. 2015 Jun 11;119(23):6099-110. doi: 10.1021/acs.jpca.5b00444. Epub 2015 Mar 25.

To study the excited state dynamics between a calcium atom and the CH3F molecule, a Ca···CH3F 1:1 complex has been prepared by a supersonic expansion with laser ablation of calcium metal in the gas phase. Tunable laser excitation of...

Rhodium-catalyzed cyclopropanation of fluorinated olefins: a straightforward route to highly functionalized fluorocyclopropanes.

Organic letters

Pons A, Beucher H, Ivashkin P, Lemonnier G, Poisson T, Charette AB, Jubault P, Pannecoucke X.
PMID: 25768041
Org Lett. 2015 Apr 03;17(7):1790-3. doi: 10.1021/acs.orglett.5b00576. Epub 2015 Mar 13.

An efficient access to highly functionalized monofluorocyclopropanes is described. The developed methodology allowed straightforward access to a large panel of polysubstituted fluorinated cyclopropanes in good to excellent yields and good diastereoselectivities. The Rh-catalyzed cyclopropanation proved to be efficient on...

New Prospects toward the Synthesis of Difluoromethylated Phosphate Mimics.

Chemistry (Weinheim an der Bergstrasse, Germany)

Ivanova MV, Bayle A, Besset T, Pannecoucke X, Poisson T.
PMID: 27334601
Chemistry. 2016 Jul 18;22(30):10284-93. doi: 10.1002/chem.201601310. Epub 2016 Jun 23.

The difluoromethyl phosphonate motif plays a crucial role in the development of bioactive molecules as it is considered as a phosphate bioisoster. Since 2010, a renewal of interest to enlarge the panel of reactions to access these difluoromethylated phosphonate-containing...

The Motion of Point Particles in Curved Spacetime.

Living reviews in relativity

Poisson E, Pound A, Vega I.
PMID: 28179832
Living Rev Relativ. 2011;14(1):7. doi: 10.12942/lrr-2011-7. Epub 2011 Sep 29.

This review is concerned with the motion of a point scalar charge, a point electric charge, and a point mass in a specified background spacetime. In each of the three cases the particle produces a field that behaves as...

The Motion of Point Particles in Curved Spacetime.

Living reviews in relativity

Poisson E.
PMID: 28179866
Living Rev Relativ. 2004;7(1):6. doi: 10.12942/lrr-2004-6. Epub 2004 May 27.

This review is concerned with the motion of a point scalar charge, a point electric charge, and a point mass in a specified background spacetime. In each of the three cases the particle produces a field that behaves as...

Photoionization of Benzophenone in the Gas Phase: Theory and Experiment.

The journal of physical chemistry. A

Khemiri N, Messaoudi S, Abderrabba M, Spighi G, Gaveau MA, Briant M, Soep B, Mestdagh JM, Hochlaf M, Poisson L.
PMID: 25866992
J Phys Chem A. 2015 Jun 11;119(23):6148-54. doi: 10.1021/acs.jpca.5b02706. Epub 2015 Apr 13.

We report on the single photoionization of jet-cooled benzophenone using a tunable source of VUV synchrotron radiation coupled with a photoion/photoelectron coincidence acquisition device. The assignment and the interpretation of the spectra are based on a characterization by ab...

LAGOS-NE: a multi-scaled geospatial and temporal database of lake ecological context and water quality for thousands of US lakes.

GigaScience

Soranno PA, Bacon LC, Beauchene M, Bednar KE, Bissell EG, Boudreau CK, Boyer MG, Bremigan MT, Carpenter SR, Carr JW, Cheruvelil KS, Christel ST, Claucherty M, Collins SM, Conroy JD, Downing JA, Dukett J, Fergus CE, Filstrup CT, Funk C, Gonzalez MJ, Green LT, Gries C, Halfman JD, Hamilton SK, Hanson PC, Henry EN, Herron EM, Hockings C, Jackson JR, Jacobson-Hedin K, Janus LL, Jones WW, Jones JR, Keson CM, King KBS, Kishbaugh SA, Lapierre JF, Lathrop B, Latimore JA, Lee Y, Lottig NR, Lynch JA, Matthews LJ, McDowell WH, Moore KEB, Neff BP, Nelson SJ, Oliver SK, Pace ML, Pierson DC, Poisson AC, Pollard AI, Post DM, Reyes PO, Rosenberry DO, Roy KM, Rudstam LG, Sarnelle O, Schuldt NJ, Scott CE, Skaff NK, Smith NJ, Spinelli NR, Stachelek JJ, Stanley EH, Stoddard JL, Stopyak SB, Stow CA, Tallant JM, Tan PN, Thorpe AP, Vanni MJ, Wagner T, Watkins G, Weathers KC, Webster KE, White JD, Wilmes MK, Yuan S.
PMID: 29053868
Gigascience. 2017 Dec 01;6(12):1-22. doi: 10.1093/gigascience/gix101.

Understanding the factors that affect water quality and the ecological services provided by freshwater ecosystems is an urgent global environmental issue. Predicting how water quality will respond to global changes not only requires water quality data, but also information...

Palladium-Catalyzed Synthesis of 3-Trifluoromethyl-Substituted 1,3-Butadienes by Means of Directed C-H Bond Functionalization.

Organic letters

Zhao Q, Tognetti V, Joubert L, Besset T, Pannecoucke X, Bouillon JP, Poisson T.
PMID: 28378584
Org Lett. 2017 Apr 21;19(8):2106-2109. doi: 10.1021/acs.orglett.7b00704. Epub 2017 Apr 05.

A palladium-catalyzed C-H bond functionalization of acrylamides was developed to build up stereoselectively trifluoromethylated 1,3-butadienes. Using a tertiary amide as a directing group, olefins were selectively functionalized with 2-bromo-3,3,3-trifluoropropene to access these important fluorinated compounds. The methodology was extended...

Recent Progress toward the Introduction of Functionalized Difluoromethylated Building Blocks onto C(sp(2) ) and C(sp) Centers.

Chemistry (Weinheim an der Bergstrasse, Germany)

Belhomme MC, Besset T, Poisson T, Pannecoucke X.
PMID: 26178870
Chemistry. 2015 Sep 07;21(37):12836-65. doi: 10.1002/chem.201501475. Epub 2015 Jul 14.

Fluorine chemistry is a field undergoing tremendous expansion. Although much attention has been paid to the introduction of the fluorine atom and the CF3 group, less interest has been devoted to the introduction of functionalized fluorinated building blocks, in...

Showing 1 to 12 of 261 entries