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Showing 1 to 12 of 42 entries
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rDNA Chromatin Activity Status as a Biomarker of Sensitivity to the RNA Polymerase I Transcription Inhibitor CX-5461.

Frontiers in cell and developmental biology

Son J, Hannan KM, Poortinga G, Hein N, Cameron DP, Ganley ARD, Sheppard KE, Pearson RB, Hannan RD, Sanij E.
PMID: 32719798
Front Cell Dev Biol. 2020 Jul 03;8:568. doi: 10.3389/fcell.2020.00568. eCollection 2020.

Hyperactivation of RNA polymerase I (Pol I) transcription of ribosomal RNA (rRNA) genes (rDNA) is a key determinant of growth and proliferation and a consistent feature of cancer cells. We have demonstrated that inhibition of rDNA transcription by the...

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

Balakirski G, Hischebeth G, Bieber T, Altengarten J, Poortinga S, Ralser-Isselstein V, Braun LM, Cunha TB, Hornung T, Engelhart S.
PMID: 34390144
J Dtsch Dermatol Ges. 2021 Aug;19(8):1211-1213. doi: 10.1111/ddg.14505_g.

No abstract available.

Interplay Between Geography and HIV Transmission Clusters in Los Angeles County.

Open forum infectious diseases

Skaathun B, Ragonnet-Cronin M, Poortinga K, Sheng Z, Hu YW, Wertheim JO.
PMID: 34159215
Open Forum Infect Dis. 2021 Apr 24;8(6):ofab211. doi: 10.1093/ofid/ofab211. eCollection 2021 Jun.

BACKGROUND: Clusters of HIV diagnoses in time and space and clusters of genetically linked cases can both serve as alerts for directing prevention and treatment activities. We assessed the interplay between geography and transmission across the Los Angeles County...

Absolute Psoriasis Area and Severity Index as a valuable marker to determine initial treatment response in psoriasis patients treated with guselkumab in routine clinical care.

Dermatologic therapy

Seidl U, Pinter A, Wilsmann-Theis D, Poortinga S, Morrison K, Mrowietz U, Gerdes S.
PMID: 34741783
Dermatol Ther. 2021 Nov 06;e15193. doi: 10.1111/dth.15193. Epub 2021 Nov 06.

Guselkumab is an anti-interleukin-23p19 monoclonal antibody approved as a first-line medication in patients with moderate-to-severe plaque-type psoriasis and second-line in active psoriatic arthritis. In the clinic, patients who have shown a lack of previous treatment efficacy and/or tolerability are...

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

Löser C, Fröhlich A, Poortinga S, Dippel E, Paul C, Czech CM, Wiemann LL, Bergmann L, Bieber T, Balakirski G.
PMID: 35040565
J Dtsch Dermatol Ges. 2022 Jan;20(1):121-128. doi: 10.1111/ddg.14648_g.

No abstract available.

Scientific truth or debate: On the link between perceived scientific consensus and belief in anthropogenic climate change.

Public understanding of science (Bristol, England)

Bertoldo R, Mays C, Böhm G, Poortinga W, Poumadère M, Tvinnereim E, Arnold A, Steentjes K, Pidgeon N.
PMID: 31359837
Public Underst Sci. 2019 Oct;28(7):778-796. doi: 10.1177/0963662519865448. Epub 2019 Jul 30.

Scientists overwhelmingly agree that climate change exists and is caused by human activity. It has been argued that communicating the consensus can counter climate scepticism, given that perceived scientific consensus is a major factor predicting public belief that climate...

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

Poortinga S, Wilsmann-Theis D, Bieber T, Wenzel J, Maier J, Sirokay J, Landsberg J, Altengarten J, Balakirski G.
PMID: 33373158
J Dtsch Dermatol Ges. 2020 Dec;18(12):1518-1521. doi: 10.1111/ddg.14168_g.

No abstract available.

Lack of effect of an externally applied electric field on bacterial adhesion to glass.

Colloids and surfaces. B, Biointerfaces

Poortinga AT, Bos R, Busscher HJ.
PMID: 11087991
Colloids Surf B Biointerfaces. 2001 Feb 01;20(2):189-194. doi: 10.1016/s0927-7765(00)00184-3.

Deposition to glass of Streptococcus salivarius HB-C12 and Staphylococcus epidermidis 3399 in a parallel plate flow chamber in the absence and presence of an externally applied electric field has been studied experimentally. No effect on bacterial adhesion, including initial...

Temporal factors in resource dilemmas.

Acta psychologica

Hendrickx L, Poortinga W, van der Kooij R.
PMID: 11569759
Acta Psychol (Amst). 2001 Sep;108(2):137-54. doi: 10.1016/s0001-6918(01)00032-4.

The conflict between present and future consumption lies at the heart of resource dilemmas (RDs), yet the role of time has received little attention in this research area. Emphasis was on factors related to the social rather than the...

Exploring the dimensionality of trust in risk regulation.

Risk analysis : an official publication of the Society for Risk Analysis

Poortinga W, Pidgeon NF.
PMID: 12969411
Risk Anal. 2003 Oct;23(5):961-72. doi: 10.1111/1539-6924.00373.

This article investigates possible differential levels of trust in government regulation across five different risk contexts and the relationship between a number of concepts that might be thought of as comprising distinctive "dimensions" of trust. It appeared that how...

Long-lived antibubbles: stable antibubbles through Pickering stabilization.

Langmuir : the ACS journal of surfaces and colloids

Poortinga AT.
PMID: 21250742
Langmuir. 2011 Mar 15;27(6):2138-41. doi: 10.1021/la1048419. Epub 2011 Jan 20.

Antibubbles, which are liquid droplets surrounded by a thin shell of gas in a liquid phase, have several promising applications, among which is encapsulation. A major hurdle toward these applications has hitherto been the inherent instability of antibubbles, leading...

Effect of Elicitors on the Plasmamembrane of Petunia hybrida Cell Suspensions : Role of DeltapH in Signal Transduction.

Plant physiology

Hagendoorn MJ, Poortinga AM, Sang HW, van der Plas LH, van Walraven HS.
PMID: 16668328
Plant Physiol. 1991 Aug;96(4):1261-7. doi: 10.1104/pp.96.4.1261.

Primary processes during elicitation of the phenylpropanoid pathway (PPP) were studied in Petunia hybrida cell suspensions. We tested the hypothesis that decrease of the proton gradient across the plasma membrane activates the PPP. Induction of the PPP was determined...

Showing 1 to 12 of 42 entries