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Showing 1 to 12 of 35 entries
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An updated h-index measures both the primary and total scientific output of a researcher.

Discoveries (Craiova, Romania)

Bucur O, Almasan A, Zubarev R, Friedman M, Nicolson GL, Sumazin P, Leabu M, Nikolajczyk BS, Avram D, Kunej T, Calin GA, Godwin AK, Adami HO, Zaphiropoulos PG, Richardson DR, Schmitt-Ulms G, Westerblad H, Keniry M, Grau GE, Carbonetto S, Stan RV, Popa-Wagner A, Takhar K, Baron BW, Galardy PJ, Yang F, Data D, Fadare O, Yeo KJ, Gabreanu GR, Andrei S, Soare GR, Nelson MA, Liehn EA.
PMID: 26504901
Discoveries (Craiova). 2015 Jul-Sep;3(3). doi: 10.15190/d.2015.42. Epub 2015 Sep 30.

The growing interest in scientometry stems from ethical concerns related to the proper evaluation of scientific contributions of an author working in a hard science. In the absence of a consensus, institutions may use arbitrary methods for evaluating scientists...

Cerebrovascular disorders: role of aging.

Journal of aging research

Popa-Wagner A, Buga AM, Turner RC, Rosen CL, Toescu E.
PMID: 22523684
J Aging Res. 2012;2012:128146. doi: 10.1155/2012/128146. Epub 2012 Mar 19.

No abstract available.

Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice.

Frontiers in aging neuroscience

Popa-Wagner A, Sandu RE, Cristin C, Uzoni A, Welle KA, Hryhorenko JR, Ghaemmaghami S.
PMID: 29503614
Front Aging Neurosci. 2018 Feb 16;10:32. doi: 10.3389/fnagi.2018.00032. eCollection 2018.

Brain structures differ in the magnitude of age-related neuron loss with the cerebellum being more affected. An underlying cause could be an age-related decline in mitochondrial bioenergetics. Successful aging of mitochondria reflects a balanced turnover of proteins involved in...

Multicellular Crosstalk Between Exosomes and the Neurovascular Unit After Cerebral Ischemia. Therapeutic Implications.

Frontiers in neuroscience

Zagrean AM, Hermann DM, Opris I, Zagrean L, Popa-Wagner A.
PMID: 30459547
Front Neurosci. 2018 Nov 06;12:811. doi: 10.3389/fnins.2018.00811. eCollection 2018.

Restorative strategies after stroke are focused on the remodeling of cerebral endothelial cells and brain parenchymal cells. The latter, i.e., neurons, neural precursor cells and glial cells, synergistically interact with endothelial cells in the ischemic brain, providing a neurovascular...

Correction to: Genetic conversion of proliferative astroglia into neurons after cerebral ischemia: a new therapeutic tool for the aged brain?.

GeroScience

Popa-Wagner A, Hermann DM, Gresita A.
PMID: 31776884
Geroscience. 2020 Feb;42(1):373. doi: 10.1007/s11357-019-00136-5.

Unfortunately, the name of the second author was incorrectly captured in the published online paper.

Electric Stimulation of Neurogenesis Improves Behavioral Recovery After Focal Ischemia in Aged Rats.

Frontiers in neuroscience

Balseanu AT, Grigore M, Pinosanu LR, Slevin M, Hermann DM, Glavan D, Popa-Wagner A.
PMID: 32742258
Front Neurosci. 2020 Jul 09;14:732. doi: 10.3389/fnins.2020.00732. eCollection 2020.

The major aim of stroke therapies is to stimulate brain repair and to improve behavioral recuperation after cerebral ischemia. Despite remarkable advances in cell therapy for stroke, stem cell-based tissue replacement has not been achieved yet stimulating the search...

Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice.

Basic research in cardiology

Gregorius J, Wang C, Stambouli O, Hussner T, Qi Y, Tertel T, Börger V, Mohamud Yusuf A, Hagemann N, Yin D, Dittrich R, Mouloud Y, Mairinger FD, Magraoui FE, Popa-Wagner A, Kleinschnitz C, Doeppner TR, Gunzer M, Meyer HE, Giebel B, Hermann DM.
PMID: 34105014
Basic Res Cardiol. 2021 Jun 08;116(1):40. doi: 10.1007/s00395-021-00881-9.

Obtained from the right cell-type, mesenchymal stromal cell (MSC)-derived small extracellular vesicles (sEVs) promote stroke recovery. Within this process, microvascular remodeling plays a central role. Herein, we evaluated the effects of MSC-sEVs on the proliferation, migration, and tube formation...

Life style, Perfusion deficits and Co-morbidities Precipitate Inflammation and Cerebrovascular Disorders in Aged Subjects.

Discoveries (Craiova, Romania)

Uzoni A, Ciobanu O, Sandu RE, Buga AM, Popa-Wagner A.
PMID: 32309564
Discoveries (Craiova). 2015 Mar 31;3(1):e39. doi: 10.15190/d.2015.31.

Cerebrovascular diseases represent 2nd leading cause of death worldwide. Understanding how genetic predispositions and their interaction with environmental factors affect cerebrovascular diseases is fundamental for prevention, diagnosis and for the development of safe and efficient therapies. Cerebrovascular diseases have...

Identification of transcriptome alterations in the prefrontal cortex, hippocampus, amygdala and hippocampus of suicide victims.

Scientific reports

Glavan D, Gheorman V, Gresita A, Hermann DM, Udristoiu I, Popa-Wagner A.
PMID: 34552157
Sci Rep. 2021 Sep 22;11(1):18853. doi: 10.1038/s41598-021-98210-6.

Suicide is one of the leading causes of death globally for all ages, and as such presents a very serious problem for clinicians worldwide. However, the underlying neurobiological pathology remains to a large extent unknown. In order to address...

Mesenchymal stromal cell-derived small extracellular vesicles promote neurological recovery and brain remodeling after distal middle cerebral artery occlusion in aged rats.

GeroScience

Dumbrava DA, Surugiu R, Börger V, Ruscu M, Tertel T, Giebel B, Hermann DM, Popa-Wagner A.
PMID: 34757568
Geroscience. 2021 Nov 10; doi: 10.1007/s11357-021-00483-2. Epub 2021 Nov 10.

Small extracellular vesicles (sEVs) obtained from mesenchymal stromal cells (MSCs) promote neurological recovery after middle cerebral artery occlusion (MCAO) in young rodents. Ischemic stroke mainly affects aged humans. MSC-sEV effects on stroke recovery in aged rodents had not been...

Deactivation of ATP-Binding Cassette Transporters ABCB1 and ABCC1 Does Not Influence Post-ischemic Neurological Deficits, Secondary Neurodegeneration and Neurogenesis, but Induces Subtle Microglial Morphological Changes.

Frontiers in cellular neuroscience

Manrique-Castano D, Sardari M, Silva de Carvalho T, Doeppner TR, Popa-Wagner A, Kleinschnitz C, Chan A, Hermann DM.
PMID: 31572128
Front Cell Neurosci. 2019 Sep 12;13:412. doi: 10.3389/fncel.2019.00412. eCollection 2019.

ATP-binding cassette (ABC) transporters prevent the access of pharmacological compounds to the ischemic brain, thereby impeding the efficacy of stroke therapies. ABC transporters can be deactivated by selective inhibitors, which potently increase the brain accumulation of drugs. Concerns have...

Very Low Efficiency of Direct Reprogramming of Astrocytes Into Neurons in the Brains of Young and Aged Mice After Cerebral Ischemia.

Frontiers in aging neuroscience

Gresita A, Glavan D, Udristoiu I, Catalin B, Hermann DM, Popa-Wagner A.
PMID: 31849638
Front Aging Neurosci. 2019 Dec 03;11:334. doi: 10.3389/fnagi.2019.00334. eCollection 2019.

After cerebral ischemia, the ratio between astroglial cells and neurons in the neurovascular unit is disrupted in the perilesional area. We hypothesized that restoring the balance within the neurovascular unit may lead to an improved neurorestoration after focal ischemia....

Showing 1 to 12 of 35 entries