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Comparison of enzymatic properties and small molecule inhibition of γ-glutamyltranspeptidases from pathogenic and commensal bacteria.

Biological chemistry

Bolz C, Bach NC, Meyer H, Müller G, Dawidowski M, Popowicz G, Sieber SA, Skerra A, Gerhard M.
PMID: 27636829
Biol Chem. 2017 Mar;398(3):341-357. doi: 10.1515/hsz-2016-0198.

Helicobacter pylori infects the stomach of 50% of the population worldwide, thus causing chronic gastritis. Although this infection can be cured by antibiotic treatment, therapeutic options are increasingly limited due to the development of resistances. The γ-glutamyl-transpeptidase (gGT) of...

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Bolz C, Bach NC, Meyer H, et al. Comparison of enzymatic properties and small molecule inhibition of γ-glutamyltranspeptidases from pathogenic and commensal bacteria. Biol Chem. 2017;398(3):341-357doi: 10.1515/hsz-2016-0198.
Bolz, C., Bach, N. C., Meyer, H., Müller, G., Dawidowski, M., Popowicz, G., Sieber, S. A., Skerra, A., & Gerhard, M. (2017). Comparison of enzymatic properties and small molecule inhibition of γ-glutamyltranspeptidases from pathogenic and commensal bacteria. Biological chemistry, 398(3), 341-357. https://doi.org/10.1515/hsz-2016-0198
Bolz, Christian, et al. "Comparison of enzymatic properties and small molecule inhibition of γ-glutamyltranspeptidases from pathogenic and commensal bacteria." Biological chemistry vol. 398,3 (2017): 341-357. doi: https://doi.org/10.1515/hsz-2016-0198
Bolz C, Bach NC, Meyer H, Müller G, Dawidowski M, Popowicz G, Sieber SA, Skerra A, Gerhard M. Comparison of enzymatic properties and small molecule inhibition of γ-glutamyltranspeptidases from pathogenic and commensal bacteria. Biol Chem. 2017 Mar;398(3):341-357. doi: 10.1515/hsz-2016-0198. PMID: 27636829.
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Quantum telescope: feasibility and constraints.

Optics letters

Kurek AR, Pięta T, Stebel T, Pollo A, Popowicz A.
PMID: 26977642
Opt Lett. 2016 Mar 15;41(6):1094-7. doi: 10.1364/OL.41.001094.

The quantum telescope is a recent idea aimed at beating the diffraction limit of spaceborne telescopes and possibly other distant target imaging systems. There is no agreement yet on the best setup of such devices, but some configurations have...

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Kurek AR, Pięta T, Stebel T, et al. Quantum telescope: feasibility and constraints. Opt Lett. 2016;41(6):1094-7doi: 10.1364/OL.41.001094.
Kurek, A. R., Pięta, T., Stebel, T., Pollo, A., & Popowicz, A. (2016). Quantum telescope: feasibility and constraints. Optics letters, 41(6), 1094-7. https://doi.org/10.1364/OL.41.001094
Kurek, A R, et al. "Quantum telescope: feasibility and constraints." Optics letters vol. 41,6 (2016): 1094-7. doi: https://doi.org/10.1364/OL.41.001094
Kurek AR, Pięta T, Stebel T, Pollo A, Popowicz A. Quantum telescope: feasibility and constraints. Opt Lett. 2016 Mar 15;41(6):1094-7. doi: 10.1364/OL.41.001094. PMID: 26977642.
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Unintentional intramuscular administration of tPA/DNase for pleural infection.

Respirology case reports

Popowicz N, Nash M, Lee YC.
PMID: 25530865
Respirol Case Rep. 2014 Dec;2(4):144-6. doi: 10.1002/rcr2.80. Epub 2014 Oct 10.

Intrapleural tissue plasminogen activator (tPA) and deoxyribonuclease (DNase) therapy has recently been shown to improve outcomes in pleural infection in a randomized trial. Published literature, to date, consists of only ∼50 patients who had received tPA/DNase. Safety data of...

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Popowicz N, Nash M, Lee YC. Unintentional intramuscular administration of tPA/DNase for pleural infection. Respirol Case Rep. 2014;2(4):144-6doi: 10.1002/rcr2.80.
Popowicz, N., Nash, M., & Lee, Y. C. (2014). Unintentional intramuscular administration of tPA/DNase for pleural infection. Respirology case reports, 2(4), 144-6. https://doi.org/10.1002/rcr2.80
Popowicz, Natalia, et al. "Unintentional intramuscular administration of tPA/DNase for pleural infection." Respirology case reports vol. 2,4 (2014): 144-6. doi: https://doi.org/10.1002/rcr2.80
Popowicz N, Nash M, Lee YC. Unintentional intramuscular administration of tPA/DNase for pleural infection. Respirol Case Rep. 2014 Dec;2(4):144-6. doi: 10.1002/rcr2.80. Epub 2014 Oct 10. PMID: 25530865; PMCID: PMC4263497.
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Trichotillomania and Trichophagia: Modern Diagnostic and Therapeutic Methods.

Dermatology and therapy

Cisoń H, Kuś A, Popowicz E, Szyca M, Reich A.
PMID: 30099694
Dermatol Ther (Heidelb). 2018 Sep;8(3):389-398. doi: 10.1007/s13555-018-0256-z. Epub 2018 Aug 11.

Trichotillomania is a chronic, mental disease of impulse control, characterized by repetitive, compulsive, and self-induced hair pulling. It can occur at any age but is observed more often in adolescents, with a strong predominance in females. Diagnosis of trichotillomania...

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Cisoń H, Kuś A, Popowicz E, et al. Trichotillomania and Trichophagia: Modern Diagnostic and Therapeutic Methods. Dermatol Ther (Heidelb). 2018;8(3):389-398doi: 10.1007/s13555-018-0256-z.
Cisoń, H., Kuś, A., Popowicz, E., Szyca, M., & Reich, A. (2018). Trichotillomania and Trichophagia: Modern Diagnostic and Therapeutic Methods. Dermatology and therapy, 8(3), 389-398. https://doi.org/10.1007/s13555-018-0256-z
Cisoń, Hanna, et al. "Trichotillomania and Trichophagia: Modern Diagnostic and Therapeutic Methods." Dermatology and therapy vol. 8,3 (2018): 389-398. doi: https://doi.org/10.1007/s13555-018-0256-z
Cisoń H, Kuś A, Popowicz E, Szyca M, Reich A. Trichotillomania and Trichophagia: Modern Diagnostic and Therapeutic Methods. Dermatol Ther (Heidelb). 2018 Sep;8(3):389-398. doi: 10.1007/s13555-018-0256-z. Epub 2018 Aug 11. PMID: 30099694; PMCID: PMC6109030.
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Usability of EU-TIRADS in the Diagnostics of Hürthle Cell Thyroid Nodules with Equivocal Cytology.

Journal of clinical medicine

Słowińska-Klencka D, Wysocka-Konieczna K, Klencki M, Popowicz B.
PMID: 33114341
J Clin Med. 2020 Oct 24;9(11). doi: 10.3390/jcm9113410.

The aim of this study was to compare the diagnostic effectiveness of EU-TIRADS in two groups of nodules with equivocal cytology (categories III-V of Bethesda system), with and without Hürthle cells (HC and non-HC). The study included 162 HC...

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Słowińska-Klencka D, Wysocka-Konieczna K, Klencki M, et al. Usability of EU-TIRADS in the Diagnostics of Hürthle Cell Thyroid Nodules with Equivocal Cytology. J Clin Med. 2020;9(11)doi: 10.3390/jcm9113410.
Słowińska-Klencka, D., Wysocka-Konieczna, K., Klencki, M., & Popowicz, B. (2020). Usability of EU-TIRADS in the Diagnostics of Hürthle Cell Thyroid Nodules with Equivocal Cytology. Journal of clinical medicine, 9(11), . https://doi.org/10.3390/jcm9113410
Słowińska-Klencka, Dorota, et al. "Usability of EU-TIRADS in the Diagnostics of Hürthle Cell Thyroid Nodules with Equivocal Cytology." Journal of clinical medicine vol. 9,11 (2020). doi: https://doi.org/10.3390/jcm9113410
Słowińska-Klencka D, Wysocka-Konieczna K, Klencki M, Popowicz B. Usability of EU-TIRADS in the Diagnostics of Hürthle Cell Thyroid Nodules with Equivocal Cytology. J Clin Med. 2020 Oct 24;9(11). doi: 10.3390/jcm9113410. PMID: 33114341; PMCID: PMC7690849.
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Validation of Four Thyroid Ultrasound Risk Stratification Systems in Patients with Hashimoto's Thyroiditis; Impact of Changes in the Threshold for Nodule's Shape Criterion.

Cancers

Słowińska-Klencka D, Klencki M, Wojtaszek-Nowicka M, Wysocka-Konieczna K, Woźniak-Oseła E, Popowicz B.
PMID: 34638380
Cancers (Basel). 2021 Sep 29;13(19). doi: 10.3390/cancers13194900.

The aim of the study was to validate thyroid US malignancy features, especially the nodule's shape, and selected Thyroid Imaging Reporting and Data Systems (EU-TIRADS; K-TIRADS; ACR-TIRADS, ATA guidelines) in patients with or without Hashimoto's thyroiditis (HT and non-HT...

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Słowińska-Klencka D, Klencki M, Wojtaszek-Nowicka M, et al. Validation of Four Thyroid Ultrasound Risk Stratification Systems in Patients with Hashimoto's Thyroiditis; Impact of Changes in the Threshold for Nodule's Shape Criterion. Cancers (Basel). 2021;13(19)doi: 10.3390/cancers13194900.
Słowińska-Klencka, D., Klencki, M., Wojtaszek-Nowicka, M., Wysocka-Konieczna, K., Woźniak-Oseła, E., & Popowicz, B. (2021). Validation of Four Thyroid Ultrasound Risk Stratification Systems in Patients with Hashimoto's Thyroiditis; Impact of Changes in the Threshold for Nodule's Shape Criterion. Cancers, 13(19), . https://doi.org/10.3390/cancers13194900
Słowińska-Klencka, Dorota, et al. "Validation of Four Thyroid Ultrasound Risk Stratification Systems in Patients with Hashimoto's Thyroiditis; Impact of Changes in the Threshold for Nodule's Shape Criterion." Cancers vol. 13,19 (2021). doi: https://doi.org/10.3390/cancers13194900
Słowińska-Klencka D, Klencki M, Wojtaszek-Nowicka M, Wysocka-Konieczna K, Woźniak-Oseła E, Popowicz B. Validation of Four Thyroid Ultrasound Risk Stratification Systems in Patients with Hashimoto's Thyroiditis; Impact of Changes in the Threshold for Nodule's Shape Criterion. Cancers (Basel). 2021 Sep 29;13(19). doi: 10.3390/cancers13194900. PMID: 34638380; PMCID: PMC8507673.
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Inhibitors of glycosomal protein import provide new leads against trypanosomiasis.

Microbial cell (Graz, Austria)

Kalel VC, Emmanouilidis L, Dawidowski M, Schliebs W, Sattler M, Popowicz GM, Erdmann R.
PMID: 28706938
Microb Cell. 2017 Jul 03;4(7):229-232. doi: 10.15698/mic2017.07.581.

Vector-borne trypanosomatid parasite infections in tropical and sub-tropical countries constitute a major threat to humans and livestock.

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Kalel VC, Emmanouilidis L, Dawidowski M, et al. Inhibitors of glycosomal protein import provide new leads against trypanosomiasis. Microb Cell. 2017;4(7):229-232doi: 10.15698/mic2017.07.581.
Kalel, V. C., Emmanouilidis, L., Dawidowski, M., Schliebs, W., Sattler, M., Popowicz, G. M., & Erdmann, R. (2017). Inhibitors of glycosomal protein import provide new leads against trypanosomiasis. Microbial cell (Graz, Austria), 4(7), 229-232. https://doi.org/10.15698/mic2017.07.581
Kalel, Vishal C, et al. "Inhibitors of glycosomal protein import provide new leads against trypanosomiasis." Microbial cell (Graz, Austria) vol. 4,7 (2017): 229-232. doi: https://doi.org/10.15698/mic2017.07.581
Kalel VC, Emmanouilidis L, Dawidowski M, Schliebs W, Sattler M, Popowicz GM, Erdmann R. Inhibitors of glycosomal protein import provide new leads against trypanosomiasis. Microb Cell. 2017 Jul 03;4(7):229-232. doi: 10.15698/mic2017.07.581. PMID: 28706938; PMCID: PMC5507685.
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Correction for Softley et al., "Structure and Molecular Recognition Mechanism of IMP-13 Metallo-β-Lactamase".

Antimicrobial agents and chemotherapy

Softley CA, Zak KM, Bostock MJ, Fino R, Zhou RX, Kolonko M, Mejdi-Nitiu R, Meyer H, Sattler M, Popowicz GM.
PMID: 32576598
Antimicrob Agents Chemother. 2020 Jun 23;64(7). doi: 10.1128/AAC.01077-20. Print 2020 Jun 23.

No abstract available.

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Softley CA, Zak KM, Bostock MJ, et al. Correction for Softley et al., "Structure and Molecular Recognition Mechanism of IMP-13 Metallo-β-Lactamase". Antimicrob Agents Chemother. 2020;64(7)doi: 10.1128/AAC.01077-20.
Softley, C. A., Zak, K. M., Bostock, M. J., Fino, R., Zhou, R. X., Kolonko, M., Mejdi-Nitiu, R., Meyer, H., Sattler, M., & Popowicz, G. M. (2020). Correction for Softley et al., "Structure and Molecular Recognition Mechanism of IMP-13 Metallo-β-Lactamase". Antimicrobial agents and chemotherapy, 64(7), . https://doi.org/10.1128/AAC.01077-20
Softley, Charlotte A, et al. "Correction for Softley et al., "Structure and Molecular Recognition Mechanism of IMP-13 Metallo-β-Lactamase"." Antimicrobial agents and chemotherapy vol. 64,7 (2020). doi: https://doi.org/10.1128/AAC.01077-20
Softley CA, Zak KM, Bostock MJ, Fino R, Zhou RX, Kolonko M, Mejdi-Nitiu R, Meyer H, Sattler M, Popowicz GM. Correction for Softley et al., "Structure and Molecular Recognition Mechanism of IMP-13 Metallo-β-Lactamase". Antimicrob Agents Chemother. 2020 Jun 23;64(7). doi: 10.1128/AAC.01077-20. Print 2020 Jun 23. PMID: 32576598; PMCID: PMC7318002.
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Repeat FNA Significantly Lowers Number of False Negative Results in Patients with Benign Nodular Thyroid Disease and Features of Chronic Thyroiditis.

International journal of endocrinology

Słowińska-Klencka D, Woźniak-Oseła E, Popowicz B, Sporny S, Klencki M.
PMID: 24812559
Int J Endocrinol. 2014;2014:967381. doi: 10.1155/2014/967381. Epub 2014 Apr 09.

Purpose. The aim of the study was to compare the risk of thyroid malignancy and efficacy of repeat FNA in patients with thyroid nodules diagnosed cytologically as benign lesion (BL) with features of chronic thyroiditis (BL-CT) and BL without...

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Słowińska-Klencka D, Woźniak-Oseła E, Popowicz B, et al. Repeat FNA Significantly Lowers Number of False Negative Results in Patients with Benign Nodular Thyroid Disease and Features of Chronic Thyroiditis. Int J Endocrinol. 2014;2014:967381doi: 10.1155/2014/967381.
Słowińska-Klencka, D., Woźniak-Oseła, E., Popowicz, B., Sporny, S., & Klencki, M. (2014). Repeat FNA Significantly Lowers Number of False Negative Results in Patients with Benign Nodular Thyroid Disease and Features of Chronic Thyroiditis. International journal of endocrinology, 2014967381. https://doi.org/10.1155/2014/967381
Słowińska-Klencka, Dorota, et al. "Repeat FNA Significantly Lowers Number of False Negative Results in Patients with Benign Nodular Thyroid Disease and Features of Chronic Thyroiditis." International journal of endocrinology vol. 2014 (2014): 967381. doi: https://doi.org/10.1155/2014/967381
Słowińska-Klencka D, Woźniak-Oseła E, Popowicz B, Sporny S, Klencki M. Repeat FNA Significantly Lowers Number of False Negative Results in Patients with Benign Nodular Thyroid Disease and Features of Chronic Thyroiditis. Int J Endocrinol. 2014;2014:967381. doi: 10.1155/2014/967381. Epub 2014 Apr 09. PMID: 24812559; PMCID: PMC4000634.
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Management of Common Bile Duct Stones Encountered During Cholecystectomy in Patients With Previous Gastric Bypass.

Frontiers in surgery

Popowicz A, Sanamrad S, Darkahi B, Zacharias R, Sandblom G.
PMID: 34957208
Front Surg. 2021 Dec 08;8:789231. doi: 10.3389/fsurg.2021.789231. eCollection 2021.

No abstract available.

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Popowicz A, Sanamrad S, Darkahi B, et al. Management of Common Bile Duct Stones Encountered During Cholecystectomy in Patients With Previous Gastric Bypass. Front Surg. 2021;8:789231doi: 10.3389/fsurg.2021.789231.
Popowicz, A., Sanamrad, S., Darkahi, B., Zacharias, R., & Sandblom, G. (2021). Management of Common Bile Duct Stones Encountered During Cholecystectomy in Patients With Previous Gastric Bypass. Frontiers in surgery, 8789231. https://doi.org/10.3389/fsurg.2021.789231
Popowicz, Agnieszka, et al. "Management of Common Bile Duct Stones Encountered During Cholecystectomy in Patients With Previous Gastric Bypass." Frontiers in surgery vol. 8 (2021): 789231. doi: https://doi.org/10.3389/fsurg.2021.789231
Popowicz A, Sanamrad S, Darkahi B, Zacharias R, Sandblom G. Management of Common Bile Duct Stones Encountered During Cholecystectomy in Patients With Previous Gastric Bypass. Front Surg. 2021 Dec 08;8:789231. doi: 10.3389/fsurg.2021.789231. eCollection 2021. PMID: 34957208; PMCID: PMC8694057.
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Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases.

Journal of molecular biology

Chrustowicz J, Sherpa D, Teyra J, Loke MS, Popowicz GM, Basquin J, Sattler M, Prabu JR, Sidhu SS, Schulman BA.
PMID: 34767800
J Mol Biol. 2021 Nov 09;434(2):167347. doi: 10.1016/j.jmb.2021.167347. Epub 2021 Nov 09.

N-degron E3 ubiquitin ligases recognize specific residues at the N-termini of substrates. Although molecular details of N-degron recognition are known for several E3 ligases, the range of N-terminal motifs that can bind a given E3 substrate binding domain remains...

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Chrustowicz J, Sherpa D, Teyra J, et al. Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases. J Mol Biol. 2021;434(2):167347doi: 10.1016/j.jmb.2021.167347.
Chrustowicz, J., Sherpa, D., Teyra, J., Loke, M. S., Popowicz, G. M., Basquin, J., Sattler, M., Prabu, J. R., Sidhu, S. S., & Schulman, B. A. (2021). Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases. Journal of molecular biology, 434(2), 167347. https://doi.org/10.1016/j.jmb.2021.167347
Chrustowicz, Jakub, et al. "Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases." Journal of molecular biology vol. 434,2 (2021): 167347. doi: https://doi.org/10.1016/j.jmb.2021.167347
Chrustowicz J, Sherpa D, Teyra J, Loke MS, Popowicz GM, Basquin J, Sattler M, Prabu JR, Sidhu SS, Schulman BA. Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases. J Mol Biol. 2021 Nov 09;434(2):167347. doi: 10.1016/j.jmb.2021.167347. Epub 2021 Nov 09. PMID: 34767800.
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Mepolizumab use in cystic fibrosis-associated allergic bronchopulmonary aspergillosis.

Respirology case reports

Boyle M, Mulrennan S, Morey S, Vekaria S, Popowicz N, Tai A.
PMID: 33304594
Respirol Case Rep. 2020 Dec 02;9(1):e00696. doi: 10.1002/rcr2.696. eCollection 2021 Jan.

Allergic bronchopulmonary aspergillosis (ABPA) is common in cystic fibrosis (CF). Treatment is challenging and the relapse rate is high. Standard therapy is oral steroids and antifungals. However, long-term systemic steroid often results in adverse effects and drug interactions between...

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Boyle M, Mulrennan S, Morey S, et al. Mepolizumab use in cystic fibrosis-associated allergic bronchopulmonary aspergillosis. Respirol Case Rep. 2020;9(1):e00696doi: 10.1002/rcr2.696.
Boyle, M., Mulrennan, S., Morey, S., Vekaria, S., Popowicz, N., & Tai, A. (2021). Mepolizumab use in cystic fibrosis-associated allergic bronchopulmonary aspergillosis. Respirology case reports, 9(1), e00696. https://doi.org/10.1002/rcr2.696
Boyle, Maeve, et al. "Mepolizumab use in cystic fibrosis-associated allergic bronchopulmonary aspergillosis." Respirology case reports vol. 9,1 (2021): e00696. doi: https://doi.org/10.1002/rcr2.696
Boyle M, Mulrennan S, Morey S, Vekaria S, Popowicz N, Tai A. Mepolizumab use in cystic fibrosis-associated allergic bronchopulmonary aspergillosis. Respirol Case Rep. 2020 Dec 02;9(1):e00696. doi: 10.1002/rcr2.696. eCollection 2021 Jan. PMID: 33304594; PMCID: PMC7710627.
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Showing 1 to 12 of 60 entries