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Showing 1 to 12 of 297 entries
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A global landscape of neuroscience public engagement efforts and the potential nexus of neuroethics

Stem education interventions

Porcello D.
GSID: cC5MkjC6rKgJ
J Das, D Porcello - Philadelphia: National Informal STEM Education …, 2019 - nisenet.org

Neuroscience is rapidly advancing, presenting new frontiers for researchers, patients, and public audiences alike. A global community of international brain research projects has sought to embed neuroethics in both practical and theoretical aspects of scientific progress and technological development....

Tendon transfer for irreparable rotator cuff tears: indications and surgical rationale.

Muscles, ligaments and tendons journal

Merolla G, Chillemi C, Franceschini V, Cerciello S, Ippolito G, Paladini P, Porcellini G.
PMID: 25767779
Muscles Ligaments Tendons J. 2015 Feb 05;4(4):425-32. eCollection 2014.

BACKGROUND: treatment of symptomatic irreparable rotator cuff tears is extremely challenging because, at present, there are no ideal solutions to this problem. Many patients respond favorably to nonsurgical treatment. However, when conservative measures fail to improve the patient's pain...

Mutations in the Mitochondrial Citrate Carrier SLC25A1 are Associated with Impaired Neuromuscular Transmission.

Journal of neuromuscular diseases

Chaouch A, Porcelli V, Cox D, Edvardson S, Scarcia P, De Grassi A, Pierri CL, Cossins J, Laval SH, Griffin H, Müller JS, Evangelista T, Töpf A, Abicht A, Huebner A, von der Hagen M, Bushby K, Straub V, Horvath R, Elpeleg O, Palace J, Senderek J, Beeson D, Palmieri L, Lochmüller H.
PMID: 26870663
J Neuromuscul Dis. 2014;1(1):75-90. doi: 10.3233/JND-140021.

BACKGROUND AND OBJECTIVE: Congenital myasthenic syndromes are rare inherited disorders characterized by fatigable weakness caused by malfunction of the neuromuscular junction. We performed whole exome sequencing to unravel the genetic aetiology in an English sib pair with clinical features...

Variations in inflammatory genes are associated with periodontitis.

Immunity & ageing : I & A

Ianni M, Bruzzesi G, Pugliese D, Porcellini E, Carbone I, Schiavone A, Licastro F.
PMID: 24274085
Immun Ageing. 2013 Oct 01;10(1):39. doi: 10.1186/1742-4933-10-39.

BACKGROUND: Periodontitis is a multi-factorial disease and several risk-factors such as infections, inflammatory responses, oral hygiene, smoke, aging and individual predisposition are involved in the disease. Pathogens trigger chronic inflammation with cytokines release which in turn leads to the...

Robotics in shoulder rehabilitation.

Muscles, ligaments and tendons journal

Sicuri C, Porcellini G, Merolla G.
PMID: 25332937
Muscles Ligaments Tendons J. 2014 Jul 14;4(2):207-13. eCollection 2014 Apr.

In the last few decades, several researches have been conducted in the field of robotic rehabilitation to meet the intensive, repetitive and task-oriented training, with the goal to recover the motor function. Up to now, robotic rehabilitation studies of...

The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanisms.

Oncoimmunology

Porcellini S, Asperti C, Valentinis B, Tiziano E, Mangia P, Bordignon C, Rizzardi GP, Traversari C.
PMID: 26451306
Oncoimmunology. 2015 Jul 01;4(10):e1041700. doi: 10.1080/2162402X.2015.1041700. eCollection 2015 Oct.

NGR-TNF is a vascular targeting agent in advanced clinical development, coupling tumor necrosis factor-α (TNF) with the CNGRCG peptide, which targets a CD13 isoform specifically expressed by angiogenic vessels. Antitumor efficacy of NGR-TNF has been described in different transplantation...

Persistent infections, immune-senescence and Alzheimer's disease.

Oncoscience

Licastro F, Porcellini E.
PMID: 27489858
Oncoscience. 2016 Jun 30;3(5):135-42. doi: 10.18632/oncoscience.309. eCollection 2016.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. Classical hallmarks of AD such as amyloid deposition and neurofibrillary tangles do not completely explain AD pathogenesis. Recent investigations proposed Aβ peptide as an...

Automation in indirect immunofluorescence testing: a new step in the evolution of the autoimmunology laboratory.

Auto- immunity highlights

Tozzoli R, Antico A, Porcelli B, Bassetti D.
PMID: 26000128
Auto Immun Highlights. 2012 Jul 13;3(2):59-65. doi: 10.1007/s13317-012-0035-2. eCollection 2012 Aug.

Indirect immunofluorescence (IIF) plays an important role in immunological and immunometric assays for detecting and measuring autoantibodies. This technology was the first multiplex method used to detect cardinal autoantibodies for the diagnosis of autoimmune diseases. Over the last 20...

Erratum to: Assessment of a combination screening assay for celiac disease.

Auto- immunity highlights

Porcelli B, Ferretti F, Vindigni C, Scapellato C, Terzuoli L.
PMID: 26000621
Auto Immun Highlights. 2011 Oct 11;3(1):33. doi: 10.1007/s13317-011-0026-8. eCollection 2012 Apr.

[This corrects the article DOI: 10.1007/s13317-011-0020-1.].

Reverse Shoulder Arthroplasty in Patients Aged Sixty Years Old or Younger: Are we Really Doing the Best?.

Translational medicine @ UniSa

Merolla G, Porcellini G.
PMID: 24809038
Transl Med UniSa. 2014 Apr 24;9:66-7. eCollection 2014 Apr.

No abstract available.

Effects of deep freezing on the energy metabolism of bovine spermatozoa during in vitro capacitation: A cytochemical approach.

Theriogenology

Ferrandi B, Lange Consiglio A, Cremonesi F, Carnevali A, Porcelli F.
PMID: 16726499
Theriogenology. 1988 Sep;30(3):563-73. doi: 10.1016/0093-691x(88)90206-3.

In order to study the effects of deep freezing on the energy metabolism of bovine spermatozoa, a cytochemical quantitative study was carried out by a microdensitometric method on cytochrome oxidase and lactate dehydrogenase (LDH) activities. These were evaluated in...

Anthrax lethal toxin-mediated killing of human and murine dendritic cells impairs the adaptive immune response.

PLoS pathogens

Alileche A, Serfass ER, Muehlbauer SM, Porcelli SA, Brojatsch J.
PMID: 16254597
PLoS Pathog. 2005 Oct;1(2):e19. doi: 10.1371/journal.ppat.0010019. Epub 2005 Oct 28.

Many pathogens have acquired strategies to combat the immune response. Bacillus anthracis interferes with host defenses by releasing anthrax lethal toxin (LT), which inactivates mitogen-activated protein kinase pathways, rendering dendritic cells (DCs) and T lymphocytes nonresponsive to immune stimulation....

Showing 1 to 12 of 297 entries