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Showing 1 to 12 of 64 entries
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Enantioselective Generation of Adjacent Stereocenters in a Copper-Catalyzed Three-Component Coupling of Imines, Allenes, and Diboranes.

Angewandte Chemie (International ed. in English)

Yeung K, Ruscoe RE, Rae J, Pulis AP, Procter DJ.
PMID: 27539673
Angew Chem Int Ed Engl. 2016 Sep 19;55(39):11912-6. doi: 10.1002/anie.201606710. Epub 2016 Aug 19.

A highly enantio- and diastereoselective copper-catalyzed three-component coupling affords the first general synthesis of homoallylic amines bearing adjacent stereocenters from achiral starting materials. The method utilizes a commercially available NHC ligand and copper source, operates at ambient temperature, couples...

Visualizing Hyperactivation in Neurodegeneration Based on Prefrontal Oxygenation: A Comparative Study of Mild Alzheimer's Disease, Mild Cognitive Impairment, and Healthy Controls.

Frontiers in aging neuroscience

Yap KH, Ung WC, Ebenezer EGM, Nordin N, Chin PS, Sugathan S, Chan SC, Yip HL, Kiguchi M, Tang TB.
PMID: 28919856
Front Aging Neurosci. 2017 Sep 01;9:287. doi: 10.3389/fnagi.2017.00287. eCollection 2017.

No abstract available.

Simultaneous occurrence of well differentiated papillary mesothelioma and endometrioid ovarian cancer: A case report.

Gynecologic oncology case reports

Gill SE, Ruple SM, Wolff CM, Puls LE.
PMID: 24371677
Gynecol Oncol Case Rep. 2013 Jan 23;4:53-5. doi: 10.1016/j.gynor.2013.01.003. eCollection 2013.

► We present a case of endometrioid ovarian cancer with concomitant well differentiated papillary mesothelioma of the peritoneum. ► Endometrioid ovarian cancer with concomitant well differentiated papillary mesothelioma is an extremely rare surgical finding of uncertain prognostic significance. ►...

An additional genus and two additional species of Forticulcitinae (Digenea: Haploporidae).

Folia parasitologica

Andres MJ, Curran SS, Fayton TJ, Pulis EE, Overstreet RM.
PMID: 25995330
Folia Parasitol (Praha). 2015 May 14;62. doi: 10.14411/fp.2015.025.

Forticulcita platana sp. n. and Forticulcita apiensis sp. n. are described from Mugil liza Valenciennes in Argentina, and from Mugil cephalus Linnaeus in Salt Springs, Florida, USA, respectively. Supplemental material relating to the hermaphroditic sac of Forticulcita gibsoni Blasco-Costa,...

Continuously coupled transcription-translation system for the production of rice cytoplasmic aldolase.

Biotechnology and bioengineering

Tulin EE, Tsutsumi K, Ejiri S.
PMID: 18623251
Biotechnol Bioeng. 1995 Mar 20;45(6):511-6. doi: 10.1002/bit.260450608.

A continuously coupled cell-free transcription-translation system was developed for the production of rice cytoplasmic aldolase, an enzyme involved in both glycolytic and gluconeogenic pathways in eukaryotic cells. The system works with a continuous flow of feeding solution containing nucleoside...

Dual vicinal functionalisation of heterocycles .

Chemical science

Šiaučiulis M, Sapmaz S, Pulis AP, Procter DJ.
PMID: 29629145
Chem Sci. 2017 Nov 17;9(3):754-759. doi: 10.1039/c7sc04723a. eCollection 2018 Jan 21.

A dual vicinal functionalisation cascade involving the union of heterocycles and allyl sulfoxides is described. In particular, the approach provides efficient one-step access to biologically relevant and synthetically important C3 thio, C2 carbo substituted indoles. The reaction operates under...

Space environment simulation and sensor calibration facility.

The Review of scientific instruments

Engelhart DP, Patton J, Plis E, Cooper R, Hoffmann R, Ferguson D, Hilmer RV, McGarity J, Holeman E.
PMID: 29495815
Rev Sci Instrum. 2018 Feb;89(2):023301. doi: 10.1063/1.4999944.

The Mumbo space environment simulation chamber discussed here comprises a set of tools to calibrate a variety of low flux, low energy electron and ion detectors used in satellite-mounted particle sensors. The chamber features electron and ion beam sources,...

Twenty-Five Years of Cancer Follow-Up; Is the Data Worth the Effort?.

Annals of surgical oncology

Brajcich BC, Palis BE, McCabe R, Nogueira L, Boffa DJ, Lum SS, Harris JB, Hawhee V, Mullett TW, Bilimoria KY, Nelson H.
PMID: 34689251
Ann Surg Oncol. 2022 Feb;29(2):828-836. doi: 10.1245/s10434-021-10668-w. Epub 2021 Oct 24.

BACKGROUND: Substantial resources are dedicated to long-term follow-up within cancer registries; however, the completeness of these data is poorly characterized. Our objectives were to quantify long-term cancer follow-up data completeness and the effort required to collect these data using...

Trends in Patient Volume by Hospital Type and the Association of These Trends With Time to Cancer Treatment Initiation.

JAMA network open

Frosch ZAK, Illenberger N, Mitra N, Boffa DJ, Facktor MA, Nelson H, Palis BE, Bekelman JE, Shulman LN, Takvorian SU.
PMID: 34241630
JAMA Netw Open. 2021 Jul 01;4(7):e2115675. doi: 10.1001/jamanetworkopen.2021.15675.

IMPORTANCE: Increasing demand for cancer care may be outpacing the capacity of hospitals to provide timely treatment, particularly at referral centers such as National Cancer Institute (NCI)-designated and academic centers. Whether the rate of patient volume growth has strained...

Collaborative, dyadic, and individual planning and physical activity: A dyadic randomized controlled trial.

Health psychology : official journal of the Division of Health Psychology, American Psychological Association

Kulis E, Szczuka Z, Keller J, Banik A, Boberska M, Kruk M, Knoll N, Radtke T, Scholz U, Rhodes RE, Luszczynska A.
PMID: 34968130
Health Psychol. 2021 Dec 30; doi: 10.1037/hea0001124. Epub 2021 Dec 30.

RESULTS: At 1-week follow-up, there were no significant Time × Condition interaction effects among target persons and partners. At 36-week follow-up, target persons and partners in the dyadic planning conditions increased their MVPA, compared to the control condition.CONCLUSIONS: Individuals...

Evaluation of Ipatasertib Interactions with Itraconazole and Coproporphyrin I and III in a Single Drug Interaction Study in Healthy Subjects.

The Journal of pharmacology and experimental therapeutics

Sane RS, Cheung KWK, Cho E, Liederer BM, Hanover J, Malhi V, Plise E, Wong S, Musib L.
PMID: 34049965
J Pharmacol Exp Ther. 2021 Aug;378(2):87-95. doi: 10.1124/jpet.121.000620. Epub 2021 May 28.

Ipatasertib is a pan-AKT inhibitor in development for the treatment of cancer. Ipatasertib was metabolized by CYP3A4 to its major metabolite, M1 (G-037720), and was a P-gp substrate and OATP1B1/1B3 inhibitor in vitro. A phase I drug-drug interaction (DDI)...

Molecular phylogeny of Diplostomum, Tylodelphys, Austrodiplostomum and Paralaria (Digenea: Diplostomidae) necessitates systematic changes and reveals a history of evolutionary host switching events.

International journal for parasitology

Achatz TJ, Martens JR, Kostadinova A, Pulis EE, Orlofske SA, Bell JA, Fecchio A, Oyarzún-Ruiz P, Syrota YY, Tkach VV.
PMID: 34371018
Int J Parasitol. 2021 Aug 06; doi: 10.1016/j.ijpara.2021.06.002. Epub 2021 Aug 06.

The Diplostomidae Poirier, 1886 is a large, globally distributed family of digeneans parasitic in intestines of their definitive hosts. Diplostomum and Tylodelphys spp. are broadly distributed, commonly reported, and the most often sequenced diplostomid genera. The majority of published...

Showing 1 to 12 of 64 entries