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Showing 1 to 12 of 15 entries
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Survival and Surgical Approach among Women with Advanced Ovarian Cancer Treated with Neoadjuvant Chemotherapy.

Journal of minimally invasive gynecology

Persenaire C, Pyrzak A, Barber EL.
PMID: 34648931
J Minim Invasive Gynecol. 2021 Oct 11; doi: 10.1016/j.jmig.2021.09.716. Epub 2021 Oct 11.

STUDY OBJECTIVE: To evaluate the effect of surgical approach on overall survival (OS) for women with advanced, epithelial ovarian cancer (EOC) after neoadjuvant chemotherapy (NACT) and determine the sociodemographic and clinical factors associated with surgical approach.DESIGN: The primary exposure...

Decreased Thyroxine Levels during rhGH Therapy in Children with Growth Hormone Deficiency.

Journal of clinical medicine

Witkowska-Sędek E, Kucharska AM, Rumińska M, Paluchowska M, Pyrżak B.
PMID: 34768618
J Clin Med. 2021 Oct 30;10(21). doi: 10.3390/jcm10215100.

BACKGROUND: Hypothyroidism in children leads to growth retardation. However, there is some evidence that recombinant human growth hormone (rhGH) therapy could suppress thyroid function. The most common observation in rhGH-treated patients is a decrease in thyroxine levels, which is...

Chronic inflammation and the growth hormone/insulin-like growth factor-1 axis.

Central-European journal of immunology

Witkowska-Sędek E, Pyrżak B.
PMID: 33613096
Cent Eur J Immunol. 2020;45(4):469-475. doi: 10.5114/ceji.2020.103422. Epub 2021 Jan 30.

Interactions between growth hormone (GH), insulin-like growth factor-1 (IGF-1), and the immune system are complex, bidirectional, but not fully explained. Current reviews based on numerous studies have indicated that chronic inflammation could suppress the GH/IGF-1 axis via several mechanisms...

Changes in leukocyte profile and C-reactive protein concentration in overweight and obese adolescents after reduction of body weight.

Central-European journal of immunology

Rumińska M, Witkowska-Sędek E, Artemniak-Wojtowicz D, Krajewska M, Majcher A, Sobol M, Pyrżak B.
PMID: 31871419
Cent Eur J Immunol. 2019;44(3):307-315. doi: 10.5114/ceji.2019.89608. Epub 2019 Sep 30.

AIM OF THE STUDY: To assess the changes in the leukocyte profile and C-reactive protein (CRP) concentration in adolescents with excess fat mass after 6-12 months of dietary intervention.MATERIAL AND METHODS: The retrospective study included 99 overweight and obese...

Serum TSH level in obese children and its correlations with atherogenic lipid indicators and carotid intima media thickness.

Journal of ultrasonography

Rumińska M, Witkowska-Sędek E, Majcher A, Brzewski M, Krawczyk M, Pyrżak B.
PMID: 30763013
J Ultrason. 2018;18(75):296-301. doi: 10.15557/JoU.2018.0043.

No abstract available.

Peripheral blood picture and aminotransferase activity in children with newly diagnosed Graves' disease at baseline and after the initiation of antithyroid drug therapy.

Central-European journal of immunology

Artemniak-Wojtowicz D, Witkowska-Sędek E, Borowiec A, Pyrżak B.
PMID: 31530982
Cent Eur J Immunol. 2019;44(2):132-137. doi: 10.5114/ceji.2019.87063. Epub 2019 Jul 30.

AIM OF THE STUDY: Assessment of the peripheral blood picture and aminotransferase activity in children with newly diagnosed Graves' disease (GD) at baseline and 4-6 weeks after the initiation of antithyroid drug (ATD) therapy.MATERIAL AND METHODS: Data of 59...

Thyroid Hormone Changes Related to Growth Hormone Therapy in Growth Hormone Deficient Patients.

Journal of clinical medicine

Kucharska AM, Witkowska-Sędek E, Rumińska M, Pyrżak B.
PMID: 34830636
J Clin Med. 2021 Nov 17;10(22). doi: 10.3390/jcm10225354.

The alterations in thyroid function during recombinant human growth hormone (rhGH) treatment have been reported by many authors since this therapy became widely available for patients with growth hormone deficiency (GHD). Decrease of thyroxine level is the most frequent...

Thyroid function in children with growth hormone deficiency during long-term growth hormone replacement therapy.

Central-European journal of immunology

Witkowska-Sędek E, Borowiec A, Majcher A, Sobol M, Rumińska M, Pyrżak B.
PMID: 30588169
Cent Eur J Immunol. 2018;43(3):255-261. doi: 10.5114/ceji.2018.80043. Epub 2018 Oct 30.

AIM OF THE STUDY: The aim of this study was to investigate the effects of growth hormone (GH) therapy on thyroid function in a group of euthyroid children with isolated idiopathic growth hormone deficiency (GHD).MATERIAL AND METHODS: The study...

Adrenal abscess in a 3-week-old neonate - a case report.

Journal of ultrasonography

Rumińska M, Witkowska-Sędek E, Warchoł S, Dudek-Warchoł T, Brzewski M, Pyrżak B.
PMID: 26807300
J Ultrason. 2015 Dec;15(63):429-37. doi: 10.15557/JoU.2015.0040. Epub 2015 Dec 28.

The authors present a case of a 6-year-old boy operated on in the 4th week of life because of adrenal abscess. The diagnosis of an adrenal abscess in the neonatal period is challenging due to its rare occurrence and...

Efficacy and safety of sirolimus therapy in familial hypoinsulinemic hypoglycemia caused by AKT2 mutation inherited from the mosaic father.

European journal of medical genetics

Dushar M, Nowaczyk J, Pyrżak B, Akopyan H, Śmigiel R, Walczak A, Rydzanicz M, Płoski R, Szczałuba K.
PMID: 34673243
Eur J Med Genet. 2021 Dec;64(12):104368. doi: 10.1016/j.ejmg.2021.104368. Epub 2021 Oct 18.

Activating mutation in the insulin signal-transducing kinase AKT2 results in severe hypoinsulinemic hypoketotic hypoglycemia and a characteristic phenotype of possible overgrowth and, sometimes, acanthosis nigricans. Herein, we describe a metabolic and hormonal profile before and during treatment with sirolimus...

Obesity and chronic inflammation crosslinking.

Central-European journal of immunology

Artemniak-Wojtowicz D, Kucharska AM, Pyrżak B.
PMID: 33658893
Cent Eur J Immunol. 2020;45(4):461-468. doi: 10.5114/ceji.2020.103418. Epub 2021 Jan 30.

The adipose tissue has been recognized as an active organ involved in numerous metabolic, hormonal and immunological processes. Obesity and associated chronic inflammation leads to many metabolic and autoimmune disorders. The number of cells, their phenotype and distribution in...

Utility of leucocyte antigens in distinguishing between bacterial and viral infection in children.

Central-European journal of immunology

Stelmaszczyk-Emmel A, Sosnowska A, Kurkowiak J, Sagała M, Zawadzka-Głos L, PyrŻak B, Demkow U.
PMID: 30588170
Cent Eur J Immunol. 2018;43(3):262-269. doi: 10.5114/ceji.2018.80044. Epub 2018 Oct 30.

INTRODUCTION: Accurate diagnosis of bacterial and viral infection is very difficult. Unfortunately, there is still no quick and discriminative diagnostic test that would help clinicians in establishing the diagnosis and taking a decision on treatment. The aim of the...

Showing 1 to 12 of 15 entries