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Showing 1 to 12 of 31 entries
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Chemical synthesis on SU-8.

Chemical communications (Cambridge, England)

Qvortrup K, Taveras KM, Thastrup O, Nielsen TE.
PMID: 21063592
Chem Commun (Camb). 2011 Jan 28;47(4):1309-11. doi: 10.1039/c0cc03876h. Epub 2010 Nov 09.

In this paper we describe a highly effective surface modification of SU-8 microparticles, the attachment of appropriate linkers for solid-supported synthesis, and the successful chemical modification of these particles via controlled multi-step organic synthesis leading to molecules attached in...

Subconjunctival Dirofilaria repens Infestation: A Light and Scanning Electron Microscopy Study.

The open ophthalmology journal

Melsom HA, Kurtzhals JA, Qvortrup K, Bargum R, Barfod TS, la Cour M, Heegaard S.
PMID: 21738560
Open Ophthalmol J. 2011;5:21-4. doi: 10.2174/1874364101105010021. Epub 2011 Apr 14.

BACKGROUND: To present a case of subconjunctival infestation with Dirofilaria repens which is very rare in Northern Europe.METHODS: A 61-year-old male presented with a swelling and redness of the left supraorbital region migrating to the eyelid and the left...

Correction: Gold-carbonyl group interactions in the electrochemistry of anthraquinone thiols self-assembled on Au(111)-surfaces.

Chemical science

Wagner M, Qvortrup K, Grier KE, Ottosen MR, Petersen JO, Tanner D, Ulstrup J, Zhang J.
PMID: 31293749
Chem Sci. 2019 May 09;10(21):5641. doi: 10.1039/c9sc90101a. eCollection 2019 Jun 07.

[This corrects the article DOI: 10.1039/C9SC00061E.].

Gold-carbonyl group interactions in the electrochemistry of anthraquinone thiols self-assembled on Au(111)-surfaces.

Chemical science

Wagner M, Qvortrup K, Grier KE, Ottosen MR, Petersen JO, Tanner D, Ulstrup J, Zhang J.
PMID: 31015932
Chem Sci. 2019 Mar 04;10(14):3927-3936. doi: 10.1039/c9sc00061e. eCollection 2019 Apr 14.

New anthraquinone derivatives with either a single or two thiol groups (AQ1 and AQ2) were synthesized and immobilized in self-assembled monolayers (SAMs) on Au(111) electrodes

Solid-phase synthesis and biological evaluation of piperazine-based novel bacterial topoisomerase inhibitors.

Bioorganic & medicinal chemistry letters

Flagstad T, Pedersen MT, Jakobsen TH, Felding J, Tolker-Nielsen T, Givskov M, Qvortrup K, Nielsen TE.
PMID: 34906671
Bioorg Med Chem Lett. 2022 Feb 01;57:128499. doi: 10.1016/j.bmcl.2021.128499. Epub 2021 Dec 11.

There is an emerging global need for new and more effective antibiotics against multi-resistant bacteria. This situation has led to massive industrial investigations on novel bacterial topoisomerase inhibitors (NBTIs) that target the vital bacterial enzymes DNA gyrase and topoisomerase...

SAR study of 4-arylazo-3,5-diamino-1.

RSC medicinal chemistry

Jansen CU, Uhd J, Andersen JB, Hultqvist LD, Jakobsen TH, Nilsson M, Nielsen TE, Givskov M, Tolker-Nielsen T, Qvortrup KM.
PMID: 34841247
RSC Med Chem. 2021 Sep 03;12(11):1868-1878. doi: 10.1039/d1md00275a. eCollection 2021 Nov 17.

By screening of a collection of 50 000 small-molecule compounds, we recently identified 4-arylazo-3,5-diamino-1

KRAS.

The Lancet. Oncology

Pfeiffer P, Qvortrup C.
PMID: 34919826
Lancet Oncol. 2021 Dec 14; doi: 10.1016/S1470-2045(21)00652-5. Epub 2021 Dec 14.

No abstract available.

KRAS.

The Lancet. Oncology

Pfeiffer P, Qvortrup C.
PMID: 34919826
Lancet Oncol. 2022 Jan;23(1):10-11. doi: 10.1016/S1470-2045(21)00652-5. Epub 2021 Dec 15.

No abstract available.

How to overcome resistance to therapy?.

Journal of gastrointestinal oncology

Qvortrup C, Tejpar S, Pfeiffer P.
PMID: 22811874
J Gastrointest Oncol. 2012 Jun;3(2):86-7. doi: 10.3978/j.issn.2078-6891.2012.015.

No abstract available.

Solid-phase synthesis and biological evaluation of piperazine-based novel bacterial topoisomerase inhibitors.

Bioorganic & medicinal chemistry letters

Flagstad T, Pedersen MT, Jakobsen TH, Felding J, Tolker-Nielsen T, Givskov M, Qvortrup K, Nielsen TE.
PMID: 34906671
Bioorg Med Chem Lett. 2021 Dec 11;57:128499. doi: 10.1016/j.bmcl.2021.128499. Epub 2021 Dec 11.

There is an emerging global need for new and more effective antibiotics against multi-resistant bacteria. This situation has led to massive industrial investigations on novel bacterial topoisomerase inhibitors (NBTIs) that target the vital bacterial enzymes DNA gyrase and topoisomerase...

Solid-phase synthesis and biological evaluation of piperazine-based novel bacterial topoisomerase inhibitors.

Bioorganic & medicinal chemistry letters

Flagstad T, Pedersen MT, Jakobsen TH, Felding J, Tolker-Nielsen T, Givskov M, Qvortrup K, Nielsen TE.
PMID: 34906671
Bioorg Med Chem Lett. 2021 Dec 11;57:128499. doi: 10.1016/j.bmcl.2021.128499. Epub 2021 Dec 11.

There is an emerging global need for new and more effective antibiotics against multi-resistant bacteria. This situation has led to massive industrial investigations on novel bacterial topoisomerase inhibitors (NBTIs) that target the vital bacterial enzymes DNA gyrase and topoisomerase...

Colorectal cancer screening in Europe: what are the next steps?.

The Lancet. Oncology

Gogenur I, Qvortrup C.
PMID: 34048687
Lancet Oncol. 2021 Jul;22(7):898-899. doi: 10.1016/S1470-2045(21)00276-X. Epub 2021 May 25.

No abstract available.

Showing 1 to 12 of 31 entries