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Effects of histamine H(3)-ligands on the levodopa-induced turning behavior of hemiparkinsonian rats.

Parkinsonism & related disorders

Huotari M, Kukkonen K, Liikka N, Potasev T, Raasmaja A, Männistö PT.
PMID: 10817955
Parkinsonism Relat Disord. 2000 Jul 01;6(3):159-164. doi: 10.1016/s1353-8020(00)00007-9.

Histamine H(3)-receptors act as heteroreceptors on many neurons. The effects of H(3)-ligands (an agonist, R-alpha-methylhistamine and an antagonist, thioperamide) on levodopa-induced turning behavior in a rat model of Parkinson's disease were quite similar to those seen with alpha(2)-adrenoceptor ligands...

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Huotari M, Kukkonen K, Liikka N, et al. Effects of histamine H(3)-ligands on the levodopa-induced turning behavior of hemiparkinsonian rats. Parkinsonism Relat Disord. 2000;6(3):159-164doi: 10.1016/s1353-8020(00)00007-9.
Huotari, M., Kukkonen, K., Liikka, N., Potasev, T., Raasmaja, A., & Männistö, P. T. (2000). Effects of histamine H(3)-ligands on the levodopa-induced turning behavior of hemiparkinsonian rats. Parkinsonism & related disorders, 6(3), 159-164. https://doi.org/10.1016/s1353-8020(00)00007-9
Huotari, et al. "Effects of histamine H(3)-ligands on the levodopa-induced turning behavior of hemiparkinsonian rats." Parkinsonism & related disorders vol. 6,3 (2000): 159-164. doi: https://doi.org/10.1016/s1353-8020(00)00007-9
Huotari M, Kukkonen K, Liikka N, Potasev T, Raasmaja A, Männistö PT. Effects of histamine H(3)-ligands on the levodopa-induced turning behavior of hemiparkinsonian rats. Parkinsonism Relat Disord. 2000 Jul 01;6(3):159-164. doi: 10.1016/s1353-8020(00)00007-9. PMID: 10817955.
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High-fat diet associated sensitization to metabolic stress in Wfs1 heterozygous mice.

Molecular genetics and metabolism

Ivask M, Volke V, Raasmaja A, Kõks S.
PMID: 34312071
Mol Genet Metab. 2021 Sep-Oct;134(1):203-211. doi: 10.1016/j.ymgme.2021.07.002. Epub 2021 Jul 13.

Wolfram syndrome is a rare autosomal recessive disorder caused by mutations in the wolframin ER transmembrane glycoprotein (WFS1) gene and characterized by diabetes mellitus, diabetes insipidus, optic atrophy and deafness. In experimental models the homozygous Wfs1 mutant mice have...

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Ivask M, Volke V, Raasmaja A, et al. High-fat diet associated sensitization to metabolic stress in Wfs1 heterozygous mice. Mol Genet Metab. 2021;134(1):203-211doi: 10.1016/j.ymgme.2021.07.002.
Ivask, M., Volke, V., Raasmaja, A., & Kõks, S. (2021). High-fat diet associated sensitization to metabolic stress in Wfs1 heterozygous mice. Molecular genetics and metabolism, 134(1), 203-211. https://doi.org/10.1016/j.ymgme.2021.07.002
Ivask, Marilin, et al. "High-fat diet associated sensitization to metabolic stress in Wfs1 heterozygous mice." Molecular genetics and metabolism vol. 134,1 (2021): 203-211. doi: https://doi.org/10.1016/j.ymgme.2021.07.002
Ivask M, Volke V, Raasmaja A, Kõks S. High-fat diet associated sensitization to metabolic stress in Wfs1 heterozygous mice. Mol Genet Metab. 2021 Sep-Oct;134(1):203-211. doi: 10.1016/j.ymgme.2021.07.002. Epub 2021 Jul 13. PMID: 34312071.
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High correlation between in vivo [123I]β-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in rats.

EJNMMI research

Bäck S, Raki M, Tuominen RK, Raasmaja A, Bergström K, Männistö PT.
PMID: 23758882
EJNMMI Res. 2013 Jun 10;3(1):46. doi: 10.1186/2191-219X-3-46.

BACKGROUND: 6-Hydroxydopamine (6-OHDA) is widely used in pre-clinical animal studies to induce degeneration of midbrain dopamine neurons to create animal models of Parkinson's disease. The aim of our study was to evaluate the potential of combined single-photon emission computed...

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Bäck S, Raki M, Tuominen RK, et al. High correlation between in vivo [123I]β-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in rats. EJNMMI Res. 2013;3(1):46doi: 10.1186/2191-219X-3-46.
Bäck, S., Raki, M., Tuominen, R. K., Raasmaja, A., Bergström, K., & Männistö, P. T. (2013). High correlation between in vivo [123I]β-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in rats. EJNMMI research, 3(1), 46. https://doi.org/10.1186/2191-219X-3-46
Bäck, Susanne, et al. "High correlation between in vivo [123I]β-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in rats." EJNMMI research vol. 3,1 (2013): 46. doi: https://doi.org/10.1186/2191-219X-3-46
Bäck S, Raki M, Tuominen RK, Raasmaja A, Bergström K, Männistö PT. High correlation between in vivo [123I]β-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in rats. EJNMMI Res. 2013 Jun 10;3(1):46. doi: 10.1186/2191-219X-3-46. PMID: 23758882; PMCID: PMC3689076.
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Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease.

Brain and behavior

Bäck S, Peränen J, Galli E, Pulkkila P, Lonka-Nevalaita L, Tamminen T, Voutilainen MH, Raasmaja A, Saarma M, Männistö PT, Tuominen RK.
PMID: 23532969
Brain Behav. 2013 Mar;3(2):75-88. doi: 10.1002/brb3.117. Epub 2013 Jan 14.

Cerebral dopamine neurotrophic factor (CDNF) protein has been shown to protect the nigrostriatal dopaminergic pathway when given as intrastriatal infusions in rat and mouse models of Parkinson's disease (PD). In this study, we assessed the neuroprotective effect of CDNF...

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Bäck S, Peränen J, Galli E, et al. Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease. Brain Behav. 2013;3(2):75-88doi: 10.1002/brb3.117.
Bäck, S., Peränen, J., Galli, E., Pulkkila, P., Lonka-Nevalaita, L., Tamminen, T., Voutilainen, M. H., Raasmaja, A., Saarma, M., Männistö, P. T., & Tuominen, R. K. (2013). Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease. Brain and behavior, 3(2), 75-88. https://doi.org/10.1002/brb3.117
Bäck, Susanne, et al. "Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease." Brain and behavior vol. 3,2 (2013): 75-88. doi: https://doi.org/10.1002/brb3.117
Bäck S, Peränen J, Galli E, Pulkkila P, Lonka-Nevalaita L, Tamminen T, Voutilainen MH, Raasmaja A, Saarma M, Männistö PT, Tuominen RK. Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease. Brain Behav. 2013 Mar;3(2):75-88. doi: 10.1002/brb3.117. Epub 2013 Jan 14. PMID: 23532969; PMCID: PMC3607149.
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High-fat diet associated sensitization to metabolic stress in Wfs1 heterozygous mice.

Molecular genetics and metabolism

Ivask M, Volke V, Raasmaja A, Kõks S.
PMID: 34312071
Mol Genet Metab. 2021 Sep-Oct;134(1):203-211. doi: 10.1016/j.ymgme.2021.07.002. Epub 2021 Jul 13.

Wolfram syndrome is a rare autosomal recessive disorder caused by mutations in the wolframin ER transmembrane glycoprotein (WFS1) gene and characterized by diabetes mellitus, diabetes insipidus, optic atrophy and deafness. In experimental models the homozygous Wfs1 mutant mice have...

Cite
Ivask M, Volke V, Raasmaja A, et al. High-fat diet associated sensitization to metabolic stress in Wfs1 heterozygous mice. Mol Genet Metab. 2021;134(1):203-211doi: 10.1016/j.ymgme.2021.07.002.
Ivask, M., Volke, V., Raasmaja, A., & Kõks, S. (2021). High-fat diet associated sensitization to metabolic stress in Wfs1 heterozygous mice. Molecular genetics and metabolism, 134(1), 203-211. https://doi.org/10.1016/j.ymgme.2021.07.002
Ivask, Marilin, et al. "High-fat diet associated sensitization to metabolic stress in Wfs1 heterozygous mice." Molecular genetics and metabolism vol. 134,1 (2021): 203-211. doi: https://doi.org/10.1016/j.ymgme.2021.07.002
Ivask M, Volke V, Raasmaja A, Kõks S. High-fat diet associated sensitization to metabolic stress in Wfs1 heterozygous mice. Mol Genet Metab. 2021 Sep-Oct;134(1):203-211. doi: 10.1016/j.ymgme.2021.07.002. Epub 2021 Jul 13. PMID: 34312071.
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Showing 1 to 5 of 5 entries