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Correction: BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions.

eLife

Bery N, Cruz-Migoni A, Bataille CJ, Quevedo CE, Tulmin H, Miller A, Russell A, Phillips SE, Carr SB, Rabbitts TH.
PMID: 30074480
Elife. 2018 Aug 02;7. doi: 10.7554/eLife.40515.

No abstract available.

Cite
Bery N, Cruz-Migoni A, Bataille CJ, et al. Correction: BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions. Elife. 2018;7doi: 10.7554/eLife.40515.
Bery, N., Cruz-Migoni, A., Bataille, C. J., Quevedo, C. E., Tulmin, H., Miller, A., Russell, A., Phillips, S. E., Carr, S. B., & Rabbitts, T. H. (2018). Correction: BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions. eLife, 7. https://doi.org/10.7554/eLife.40515
Bery, Nicolas, et al. "Correction: BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions." eLife vol. 7 (2018). doi: https://doi.org/10.7554/eLife.40515
Bery N, Cruz-Migoni A, Bataille CJ, Quevedo CE, Tulmin H, Miller A, Russell A, Phillips SE, Carr SB, Rabbitts TH. Correction: BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions. Elife. 2018 Aug 02;7. doi: 10.7554/eLife.40515. PMID: 30074480; PMCID: PMC6075862.
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Immunopolymer Lipid Nanoparticles for Delivery of Macromolecules to Antigen-Expressing Cells.

ACS applied bio materials

Jain AK, Bataille CJR, Milhas S, Miller A, Zhang J, Rabbitts TH.
PMID: 35019618
ACS Appl Bio Mater. 2020 Dec 21;3(12):8481-8495. doi: 10.1021/acsabm.0c00857. Epub 2020 Nov 20.

Macromolecules such as antibodies and antibody fragments have been reported to interfere with intracellular targets, but their use is limited to delivery systems where expression is achieved from vectors such as plasmids or viruses. We have developed PEGylated nanoparticles...

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Jain AK, Bataille CJR, Milhas S, et al. Immunopolymer Lipid Nanoparticles for Delivery of Macromolecules to Antigen-Expressing Cells. ACS Appl Bio Mater. 2020;3(12):8481-8495doi: 10.1021/acsabm.0c00857.
Jain, A. K., Bataille, C. J. R., Milhas, S., Miller, A., Zhang, J., & Rabbitts, T. H. (2020). Immunopolymer Lipid Nanoparticles for Delivery of Macromolecules to Antigen-Expressing Cells. ACS applied bio materials, 3(12), 8481-8495. https://doi.org/10.1021/acsabm.0c00857
Jain, Arvind K, et al. "Immunopolymer Lipid Nanoparticles for Delivery of Macromolecules to Antigen-Expressing Cells." ACS applied bio materials vol. 3,12 (2020): 8481-8495. doi: https://doi.org/10.1021/acsabm.0c00857
Jain AK, Bataille CJR, Milhas S, Miller A, Zhang J, Rabbitts TH. Immunopolymer Lipid Nanoparticles for Delivery of Macromolecules to Antigen-Expressing Cells. ACS Appl Bio Mater. 2020 Dec 21;3(12):8481-8495. doi: 10.1021/acsabm.0c00857. Epub 2020 Nov 20. PMID: 35019618.
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Trajectories, risk factors, and impact of persistent pain after major musculoskeletal surgery in adolescents: a replication study.

The journal of pain

Ellyson AM, Gordon G, Zhou C, Rabbitts JA.
PMID: 34974171
J Pain. 2021 Dec 30; doi: 10.1016/j.jpain.2021.12.009. Epub 2021 Dec 30.

Studies have identified high rates of chronic postsurgical pain in adolescents. Characterizing patterns of pain in the transition from acute to chronic following major surgery may pinpoint critical periods of recovery. This observational study modelled pain trajectories over 1-year...

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Ellyson AM, Gordon G, Zhou C, et al. Trajectories, risk factors, and impact of persistent pain after major musculoskeletal surgery in adolescents: a replication study. J Pain. 2021;doi: 10.1016/j.jpain.2021.12.009.
Ellyson, A. M., Gordon, G., Zhou, C., & Rabbitts, J. A. (2021). Trajectories, risk factors, and impact of persistent pain after major musculoskeletal surgery in adolescents: a replication study. The journal of pain, . https://doi.org/10.1016/j.jpain.2021.12.009
Ellyson, Alice M, et al. "Trajectories, risk factors, and impact of persistent pain after major musculoskeletal surgery in adolescents: a replication study." The journal of pain vol. (2021). doi: https://doi.org/10.1016/j.jpain.2021.12.009
Ellyson AM, Gordon G, Zhou C, Rabbitts JA. Trajectories, risk factors, and impact of persistent pain after major musculoskeletal surgery in adolescents: a replication study. J Pain. 2021 Dec 30; doi: 10.1016/j.jpain.2021.12.009. Epub 2021 Dec 30. PMID: 34974171.
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A cell-based screening method using an intracellular antibody for discovering small molecules targeting the translocation protein LMO2.

Science advances

Bery N, Bataille CJR, Russell A, Hayes A, Raynaud F, Milhas S, Anand S, Tulmin H, Miller A, Rabbitts TH.
PMID: 33837087
Sci Adv. 2021 Apr 09;7(15). doi: 10.1126/sciadv.abg1950. Print 2021 Apr.

Intracellular antibodies are tools that can be used directly for target validation by interfering with properties like protein-protein interactions. An alternative use of intracellular antibodies in drug discovery is developing small-molecule surrogates using antibody-derived (Abd) technology. We previously used...

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Bery N, Bataille CJR, Russell A, et al. A cell-based screening method using an intracellular antibody for discovering small molecules targeting the translocation protein LMO2. Sci Adv. 2021;7(15)doi: 10.1126/sciadv.abg1950.
Bery, N., Bataille, C. J. R., Russell, A., Hayes, A., Raynaud, F., Milhas, S., Anand, S., Tulmin, H., Miller, A., & Rabbitts, T. H. (2021). A cell-based screening method using an intracellular antibody for discovering small molecules targeting the translocation protein LMO2. Science advances, 7(15), . https://doi.org/10.1126/sciadv.abg1950
Bery, Nicolas, et al. "A cell-based screening method using an intracellular antibody for discovering small molecules targeting the translocation protein LMO2." Science advances vol. 7,15 (2021). doi: https://doi.org/10.1126/sciadv.abg1950
Bery N, Bataille CJR, Russell A, Hayes A, Raynaud F, Milhas S, Anand S, Tulmin H, Miller A, Rabbitts TH. A cell-based screening method using an intracellular antibody for discovering small molecules targeting the translocation protein LMO2. Sci Adv. 2021 Apr 09;7(15). doi: 10.1126/sciadv.abg1950. Print 2021 Apr. PMID: 33837087; PMCID: PMC8034850.
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Correction to: A digital health peri-operative cognitive-behavioral intervention to prevent transition from acute to chronic postsurgical pain in adolescents undergoing spinal fusion (SurgeryPal.

Trials

Rabbitts JA, Zhou C, de la Vega R, Aalfs H, Murray CB, Palermo TM.
PMID: 34548100
Trials. 2021 Sep 21;22(1):646. doi: 10.1186/s13063-021-05596-9.

No abstract available.

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Rabbitts JA, Zhou C, de la Vega R, et al. Correction to: A digital health peri-operative cognitive-behavioral intervention to prevent transition from acute to chronic postsurgical pain in adolescents undergoing spinal fusion (SurgeryPal. Trials. 2021;22(1):646doi: 10.1186/s13063-021-05596-9.
Rabbitts, J. A., Zhou, C., de la Vega, R., Aalfs, H., Murray, C. B., & Palermo, T. M. (2021). Correction to: A digital health peri-operative cognitive-behavioral intervention to prevent transition from acute to chronic postsurgical pain in adolescents undergoing spinal fusion (SurgeryPal. Trials, 22(1), 646. https://doi.org/10.1186/s13063-021-05596-9
Rabbitts, Jennifer A, et al. "Correction to: A digital health peri-operative cognitive-behavioral intervention to prevent transition from acute to chronic postsurgical pain in adolescents undergoing spinal fusion (SurgeryPal." Trials vol. 22,1 (2021): 646. doi: https://doi.org/10.1186/s13063-021-05596-9
Rabbitts JA, Zhou C, de la Vega R, Aalfs H, Murray CB, Palermo TM. Correction to: A digital health peri-operative cognitive-behavioral intervention to prevent transition from acute to chronic postsurgical pain in adolescents undergoing spinal fusion (SurgeryPal. Trials. 2021 Sep 21;22(1):646. doi: 10.1186/s13063-021-05596-9. PMID: 34548100; PMCID: PMC8454081.
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Antibody diversification by somatic mutation.

Immunology today

Rabbitts TH.
PMID: 25290454
Immunol Today. 1981 Nov;2(11):211-2. doi: 10.1016/0167-5699(81)90048-7.

No abstract available.

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Rabbitts TH. Antibody diversification by somatic mutation. Immunol Today. 1981;2(11):211-2doi: 10.1016/0167-5699(81)90048-7.
Rabbitts, T. H. (1981). Antibody diversification by somatic mutation. Immunology today, 2(11), 211-2. https://doi.org/10.1016/0167-5699(81)90048-7
Rabbitts, T H. "Antibody diversification by somatic mutation." Immunology today vol. 2,11 (1981): 211-2. doi: https://doi.org/10.1016/0167-5699(81)90048-7
Rabbitts TH. Antibody diversification by somatic mutation. Immunol Today. 1981 Nov;2(11):211-2. doi: 10.1016/0167-5699(81)90048-7. PMID: 25290454.
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Immunopolymer Lipid Nanoparticles for Delivery of Macromolecules to Antigen-Expressing Cells.

ACS applied bio materials

Jain AK, Bataille CJR, Milhas S, Miller A, Zhang J, Rabbitts TH.
PMID: 35019618
ACS Appl Bio Mater. 2020 Dec 21;3(12):8481-8495. doi: 10.1021/acsabm.0c00857. Epub 2020 Nov 20.

Macromolecules such as antibodies and antibody fragments have been reported to interfere with intracellular targets, but their use is limited to delivery systems where expression is achieved from vectors such as plasmids or viruses. We have developed PEGylated nanoparticles...

Cite
Jain AK, Bataille CJR, Milhas S, et al. Immunopolymer Lipid Nanoparticles for Delivery of Macromolecules to Antigen-Expressing Cells. ACS Appl Bio Mater. 2020;3(12):8481-8495doi: 10.1021/acsabm.0c00857.
Jain, A. K., Bataille, C. J. R., Milhas, S., Miller, A., Zhang, J., & Rabbitts, T. H. (2020). Immunopolymer Lipid Nanoparticles for Delivery of Macromolecules to Antigen-Expressing Cells. ACS applied bio materials, 3(12), 8481-8495. https://doi.org/10.1021/acsabm.0c00857
Jain, Arvind K, et al. "Immunopolymer Lipid Nanoparticles for Delivery of Macromolecules to Antigen-Expressing Cells." ACS applied bio materials vol. 3,12 (2020): 8481-8495. doi: https://doi.org/10.1021/acsabm.0c00857
Jain AK, Bataille CJR, Milhas S, Miller A, Zhang J, Rabbitts TH. Immunopolymer Lipid Nanoparticles for Delivery of Macromolecules to Antigen-Expressing Cells. ACS Appl Bio Mater. 2020 Dec 21;3(12):8481-8495. doi: 10.1021/acsabm.0c00857. Epub 2020 Nov 20. PMID: 35019618.
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Racial and ethnic differences in pediatric surgery utilization in the United States: A nationally representative cross-sectional analysis.

Journal of pediatric surgery

Groenewald CB, Lee HH, Jimenez N, Ehie O, Rabbitts JA.
PMID: 34742576
J Pediatr Surg. 2021 Oct 22; doi: 10.1016/j.jpedsurg.2021.10.011. Epub 2021 Oct 22.

OBJECTIVES: Children of minority background have reduced access to surgery. This study assessed for racial/ethnic differences in surgical utilization by location.MATERIALS AND METHODS: We conducted a cross-sectional analysis of U.S. children (0-17 years of age) participating in the nationally...

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Groenewald CB, Lee HH, Jimenez N, et al. Racial and ethnic differences in pediatric surgery utilization in the United States: A nationally representative cross-sectional analysis. J Pediatr Surg. 2021;doi: 10.1016/j.jpedsurg.2021.10.011.
Groenewald, C. B., Lee, H. H., Jimenez, N., Ehie, O., & Rabbitts, J. A. (2021). Racial and ethnic differences in pediatric surgery utilization in the United States: A nationally representative cross-sectional analysis. Journal of pediatric surgery, . https://doi.org/10.1016/j.jpedsurg.2021.10.011
Groenewald, Cornelius B, et al. "Racial and ethnic differences in pediatric surgery utilization in the United States: A nationally representative cross-sectional analysis." Journal of pediatric surgery vol. (2021). doi: https://doi.org/10.1016/j.jpedsurg.2021.10.011
Groenewald CB, Lee HH, Jimenez N, Ehie O, Rabbitts JA. Racial and ethnic differences in pediatric surgery utilization in the United States: A nationally representative cross-sectional analysis. J Pediatr Surg. 2021 Oct 22; doi: 10.1016/j.jpedsurg.2021.10.011. Epub 2021 Oct 22. PMID: 34742576.
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NMR waterLOGSY as An Assay in Drug Development Programmes for Detecting Protein-Ligand Interactions-NMR waterLOGSY.

Bio-protocol

Bataille CJR, Rabbitts TH, Claridge TDW.
PMID: 33659336
Bio Protoc. 2020 Jul 05;10(13):e3666. doi: 10.21769/BioProtoc.3666. eCollection 2020 Jul 05.

In drug development programmes, multiple assays are needed for the determination of protein-compound interactions and evaluation of potential use in assays with protein-protein interactions. In this protocol we describe the waterLOGSY NMR method for confirming protein-ligand binding events.

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Bataille CJR, Rabbitts TH, Claridge TDW. NMR waterLOGSY as An Assay in Drug Development Programmes for Detecting Protein-Ligand Interactions-NMR waterLOGSY. Bio Protoc. 2020;10(13):e3666doi: 10.21769/BioProtoc.3666.
Bataille, C. J. R., Rabbitts, T. H., & Claridge, T. D. W. (2020). NMR waterLOGSY as An Assay in Drug Development Programmes for Detecting Protein-Ligand Interactions-NMR waterLOGSY. Bio-protocol, 10(13), e3666. https://doi.org/10.21769/BioProtoc.3666
Bataille, Carole J R, et al. "NMR waterLOGSY as An Assay in Drug Development Programmes for Detecting Protein-Ligand Interactions-NMR waterLOGSY." Bio-protocol vol. 10,13 (2020): e3666. doi: https://doi.org/10.21769/BioProtoc.3666
Bataille CJR, Rabbitts TH, Claridge TDW. NMR waterLOGSY as An Assay in Drug Development Programmes for Detecting Protein-Ligand Interactions-NMR waterLOGSY. Bio Protoc. 2020 Jul 05;10(13):e3666. doi: 10.21769/BioProtoc.3666. eCollection 2020 Jul 05. PMID: 33659336; PMCID: PMC7842718.
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LINGO-1 is a New Therapy Target and Biomarker for Ewing Sarcoma.

Clinics in oncology (Belmont, Calif.)

Jain A, Zhang J, Rabbitts T.
PMID: 30613826
Clin Oncol (Belmont). 2017 Jan 05;2:1183.

Ewing sarcoma is a predominantly paediatric cancer with a high rate of metastasis and reoccurrence. A new surface marker called LINGO-1 was recently identified on Ewing tumours as a potential target for antibody-mediated therapies. However, such targeting requires caution...

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Jain A, Zhang J, Rabbitts T. LINGO-1 is a New Therapy Target and Biomarker for Ewing Sarcoma. Clin Oncol (Belmont). 2017;2:1183
Jain, A., Zhang, J., & Rabbitts, T. (2017). LINGO-1 is a New Therapy Target and Biomarker for Ewing Sarcoma. Clinics in oncology (Belmont, Calif.), 21183.
Jain, Arvind, et al. "LINGO-1 is a New Therapy Target and Biomarker for Ewing Sarcoma." Clinics in oncology (Belmont, Calif.) vol. 2 (2017): 1183.
Jain A, Zhang J, Rabbitts T. LINGO-1 is a New Therapy Target and Biomarker for Ewing Sarcoma. Clin Oncol (Belmont). 2017 Jan 05;2:1183. PMID: 30613826; PMCID: PMC6314441.
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Past and future impact of next-generation sequencing in head and neck cancer.

Head & neck

Sethi N, MacLennan K, Wood HM, Rabbitts P.
PMID: 25900457
Head Neck. 2016 Apr;38:E2395-402. doi: 10.1002/hed.24085. Epub 2015 Jul 20.

Progress in sequencing technology is intrinsically linked to progress in understanding cancer genomics. The purpose of this review was to discuss the development from Sanger sequencing to next-generation sequencing (NGS) technology. We highlight the technical considerations for understanding reports...

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Sethi N, MacLennan K, Wood HM, et al. Past and future impact of next-generation sequencing in head and neck cancer. Head Neck. 2015;38:E2395-402doi: 10.1002/hed.24085.
Sethi, N., MacLennan, K., Wood, H. M., & Rabbitts, P. (2016). Past and future impact of next-generation sequencing in head and neck cancer. Head & neck, 38E2395-402. https://doi.org/10.1002/hed.24085
Sethi, Neeraj, et al. "Past and future impact of next-generation sequencing in head and neck cancer." Head & neck vol. 38 (2016): E2395-402. doi: https://doi.org/10.1002/hed.24085
Sethi N, MacLennan K, Wood HM, Rabbitts P. Past and future impact of next-generation sequencing in head and neck cancer. Head Neck. 2016 Apr;38:E2395-402. doi: 10.1002/hed.24085. Epub 2015 Jul 20. PMID: 25900457.
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Evaluating the psychometric properties of the Widespread Pain Index and the Symptom Severity scale in youth with painful conditions.

Canadian journal of pain = Revue canadienne de la douleur

Dudeney J, Law EF, Meyyappan A, Palermo TM, Rabbitts JA.
PMID: 32051925
Can J Pain. 2019;3(1):137-147. doi: 10.1080/24740527.2019.1620097. Epub 2019 Jun 26.

BACKGROUND: Assessing features of centralized pain may prove to be clinically meaningful in pediatric populations. However, we are currently limited by the lack of validated pediatric measures.AIM: We examined the psychometric properties of the Widespread Pain Index (WPI) and...

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Dudeney J, Law EF, Meyyappan A, et al. Evaluating the psychometric properties of the Widespread Pain Index and the Symptom Severity scale in youth with painful conditions. Can J Pain. 2019;3(1):137-147doi: 10.1080/24740527.2019.1620097.
Dudeney, J., Law, E. F., Meyyappan, A., Palermo, T. M., & Rabbitts, J. A. (2019). Evaluating the psychometric properties of the Widespread Pain Index and the Symptom Severity scale in youth with painful conditions. Canadian journal of pain = Revue canadienne de la douleur, 3(1), 137-147. https://doi.org/10.1080/24740527.2019.1620097
Dudeney, Joanne, et al. "Evaluating the psychometric properties of the Widespread Pain Index and the Symptom Severity scale in youth with painful conditions." Canadian journal of pain = Revue canadienne de la douleur vol. 3,1 (2019): 137-147. doi: https://doi.org/10.1080/24740527.2019.1620097
Dudeney J, Law EF, Meyyappan A, Palermo TM, Rabbitts JA. Evaluating the psychometric properties of the Widespread Pain Index and the Symptom Severity scale in youth with painful conditions. Can J Pain. 2019;3(1):137-147. doi: 10.1080/24740527.2019.1620097. Epub 2019 Jun 26. PMID: 32051925; PMCID: PMC7015535.
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Showing 1 to 12 of 18 entries