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The murine appendiceal microbiome is altered in spontaneous colitis and its pathological progression.

Gut pathogens

Alkadhi S, Kunde D, Cheluvappa R, Randall-Demllo S, Eri R.
PMID: 25002910
Gut Pathog. 2014 Jun 21;6:25. doi: 10.1186/1757-4749-6-25. eCollection 2014.

BACKGROUND: Inflammatory bowel disease (comprising ulcerative colitis and Crohn's disease) is a multifactorial disease that is extensively associated with stool microbiome changes (dysbiosis). Appendicitis and appendectomy limits subsequent colitis, clinically, and in animal models. We wanted to examine how...

Intestinal epithelium and autophagy: partners in gut homeostasis.

Frontiers in immunology

Randall-Demllo S, Chieppa M, Eri R.
PMID: 24137160
Front Immunol. 2013 Sep 30;4:301. doi: 10.3389/fimmu.2013.00301.

One of the most significant challenges of cell biology is to understand how each type of cell copes with its specific workload without suffering damage. Among the most intriguing questions concerns intestinal epithelial cells in mammals; these cells act...

Showing 1 to 2 of 2 entries