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Showing 1 to 12 of 20 entries
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An integrated methodology for recording uncertainties about environmental data.

Water science and technology : a journal of the International Association on Water Pollution Research

Brown JD, Heuvelink GB, Refsgaard JC.
PMID: 16304947
Water Sci Technol. 2005;52(6):153-60.

Understanding the limitations of environmental data is essential both for managing environmental systems effectively and for encouraging the responsible use of scientific research when knowledge is limited and priorities are varied. Using a combination of quantitative and qualitative techniques...

Clinical Outcomes and Response to Vericiguat According to Index Heart Failure Event: Insights From the VICTORIA Trial.

JAMA cardiology

Lam CSP, Giczewska A, Sliwa K, Edelmann F, Refsgaard J, Bocchi E, Ezekowitz JA, Hernandez AF, O'Connor CM, Roessig L, Patel MJ, Pieske B, Anstrom KJ, Armstrong PW.
PMID: 33185650
JAMA Cardiol. 2021 Jun 01;6(6):706-712. doi: 10.1001/jamacardio.2020.6455.

IMPORTANCE: The period following heart failure hospitalization (HFH) is a vulnerable time with high rates of death or recurrent HFH.OBJECTIVE: To evaluate clinical characteristics, outcomes, and treatment response to vericiguat according to prespecified index event subgroups and time from...

Mutation analysis of the candidate genes .

Applied & translational genomics

Refsgaard L, Olesen MS, Møller DV, Christiansen M, Haunsø S, Svendsen JH, Christensen AH.
PMID: 27896052
Appl Transl Genom. 2012 Oct 01;1:44-46. doi: 10.1016/j.atg.2012.06.001. eCollection 2012 Dec 01.

INTRODUCTION: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetically determined heart disease characterized by fibrofatty infiltrations in the myocardium, right and/or left ventricular involvement, and ventricular tachyarrhythmias. Although ten genes have been associated with ARVC, only about 40% of...

Effect of antianginal medication on resting myocardial perfusion and pharmacologically induced hyperemia.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Bøttcher M, Refsgaard J, Madsen MM, Randsbæk F, Kaltoft A, Bøtker HE, Nielsen TT.
PMID: 12734468
J Nucl Cardiol. 2000;10:E001-E008.

Background. Patients scheduled for myocardial perfusion imaging are often taking several antianginal drugs. There is presently no consensus concerning a regimen of discontinuation before either rest or pharmacologic stress myocardial perfusion imaging. Whether antianginal treatment affects diagnostic sensitivity and...

Effects of changes in land use and climate on aquatic ecosystems: Coupling of models and decomposition of uncertainties.

The Science of the total environment

Trolle D, Nielsen A, Andersen HE, Thodsen H, Olesen JE, Børgesen CD, Refsgaard JC, Sonnenborg TO, Karlsson IB, Christensen JP, Markager S, Jeppesen E.
PMID: 30677929
Sci Total Environ. 2019 Mar 20;657:627-633. doi: 10.1016/j.scitotenv.2018.12.055. Epub 2018 Dec 05.

To analyse the potential future ecological state of estuaries located in the temperate climate (here exemplified with the Odense Fjord estuary, Denmark), we combined end-of-the-century climate change projections from four different climate models, four contrasting land use scenarios ("Agriculture...

Shared care versus hospital-based cardiac rehabilitation: a cost-utility analysis based on a randomised controlled trial.

Open heart

Bertelsen JB, Dehbarez NT, Refsgaard J, Kanstrup H, Johnsen SP, Qvist I, Christensen B, Søgaard R, Christensen KL.
PMID: 29531754
Open Heart. 2018 Feb 07;5(1):e000584. doi: 10.1136/openhrt-2016-000584. eCollection 2018.

BACKGROUND: Changes in the organisation of chronic healthcare, an increased awareness of costs and challenges of low adherence in cardiac rehabilitation (CR) call for the exploration of more flexible CR programmes as alternatives to hospital-based CR (H-CR). A model...

"Future Patient" Telerehabilitation for Patients With Heart Failure: Protocol for a Randomized Controlled Trial.

JMIR research protocols

Dinesen B, Dittmann L, Gade JD, Jørgensen CK, Hollingdal M, Leth S, Melholt C, Spindler H, Refsgaard J.
PMID: 31538944
JMIR Res Protoc. 2019 Sep 19;8(9):e14517. doi: 10.2196/14517.

BACKGROUND: Cardiovascular disease is the leading cause of mortality worldwide, accounting for 13%-15% of all deaths. Cardiac rehabilitation has poor compliance and adherence. Telerehabilitation has been introduced to increase patients' participation, access, and adherence with the help of digital...

Motivating patients in cardiac rehabilitation programs: A multicenter randomized controlled trial.

International journal of telerehabilitation

Spindler H, Hollingdal M, Refsgaard J, Dinesen B.
PMID: 34345341
Int J Telerehabil. 2021 Jun 22;13(1):e6365. doi: 10.5195/ijt.2021.6365. eCollection 2021.

Concerns have been raised about motivation and psychological distress when implementing telerehabilitation in patients with heart failure. The current study compared conventional and telerehabilitation in two groups (n=67; n=70) of patients with heart failure at 0, 6, and 12...

Screening of the ito regulatory subunit klf15 in patients with early-onset lone atrial fibrillation.

Frontiers in genetics

Nielsen MW, Olesen MS, Refsgaard L, Haunsø S, Svendsen JH.
PMID: 23730307
Front Genet. 2013 May 17;4:88. doi: 10.3389/fgene.2013.00088. eCollection 2013.

Several studies have associated mutations in genes encoding potassium channels and accessory subunits involved in cardiac repolarization with increased susceptibility of atrial fibrillation (AF). Recently, the Krüppel-like factor 15 (Klf15) was found to transcriptionally control rhythmic expression of KChIP2,...

Local control on precipitation in a fully coupled climate-hydrology model.

Scientific reports

Larsen MA, Christensen JH, Drews M, Butts MB, Refsgaard JC.
PMID: 26960564
Sci Rep. 2016 Mar 10;6:22927. doi: 10.1038/srep22927.

The ability to simulate regional precipitation realistically by climate models is essential to understand and adapt to climate change. Due to the complexity of associated processes, particularly at unresolved temporal and spatial scales this continues to be a major...

Clinical Outcomes and Response to Vericiguat According to Index Heart Failure Event: Insights From the VICTORIA Trial.

JAMA cardiology

Lam CSP, Giczewska A, Sliwa K, Edelmann F, Refsgaard J, Bocchi E, Ezekowitz JA, Hernandez AF, O'Connor CM, Roessig L, Patel MJ, Pieske B, Anstrom KJ, Armstrong PW.
PMID: 33185650
JAMA Cardiol. 2021 Jun 01;6(6):706-712. doi: 10.1001/jamacardio.2020.6455.

IMPORTANCE: The period following heart failure hospitalization (HFH) is a vulnerable time with high rates of death or recurrent HFH.OBJECTIVE: To evaluate clinical characteristics, outcomes, and treatment response to vericiguat according to prespecified index event subgroups and time from...

Comparison and evaluation of model structures for the simulation of pollution fluxes in a tile-drained river basin.

Journal of environmental quality

Hoang L, van Griensven A, van der Keur P, Refsgaard JC, Troldborg L, Nilsson B, Mynett A.
PMID: 25602543
J Environ Qual. 2014 Jan;43(1):86-99. doi: 10.2134/jeq2011.0398.

The European Union Water Framework Directive requires an integrated pollution prevention plan at the river basin level. Hydrological river basin modeling tools are therefore promising tools to support the quantification of pollution originating from different sources. A limited number...

Showing 1 to 12 of 20 entries