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Showing 1 to 12 of 38 entries
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The gibberellin precursor GA12 acts as a long-distance growth signal in Arabidopsis.

Nature plants

Regnault T, Davière JM, Wild M, Sakvarelidze-Achard L, Heintz D, Carrera Bergua E, Lopez Diaz I, Gong F, Hedden P, Achard P.
PMID: 27250008
Nat Plants. 2015 Jun 01;1:15073. doi: 10.1038/nplants.2015.73.

The gibberellin (GA) phytohormones play important roles in plant growth and development, promoting seed germination, elongation growth and reproductive development(1). Over the years, substantial progress has been made in understanding the regulation of GA signalling and metabolism, which ensures...

Health Benefits of Supplementing Nursery Pig Diets with Microalgae or Fish Oil.

Animals : an open access journal from MDPI

Lee AV, You L, Oh SY, Li Z, Code A, Zhu C, Fisher-Heffernan RE, Regnault TRH, De Lange CFM, Huber LA, Karrow NA.
PMID: 30841603
Animals (Basel). 2019 Mar 05;9(3). doi: 10.3390/ani9030080.

Weaning stress can negatively impact a pig's performance; dietary supplementation with omega-3 polyunsaturated fatty acids (n-3 PUFA) reduces inflammatory stress and promotes nursery pig's health and growth. Fish oil (FO) is a major source of n-3 PUFA; however, microalgae...

Evaluating the Effectiveness of Yttrium-90 Glass Microspheres in the Treatment of Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma, and Metastatic Colorectal Cancer in Practice: Protocol for the Prospective PROACTIF Phase IV Registry Study in France.

Cardiovascular and interventional radiology

Garin E, Pinaquy JB, Bailly C, Sengel C, Mariano-Goulart D, Edeline J, Blanc JF, Bouvier A, Tordo J, Rode A, Becker S, Sefrioui D, de Baere T, Somma C, Mastier C, Goupil J, Chevallier P, Regnault H, Vibert E, Manfredi S, Vicaut E, Patel B, Boucher E, Guiu B.
PMID: 34796373
Cardiovasc Intervent Radiol. 2021 Nov 18; doi: 10.1007/s00270-021-03002-0. Epub 2021 Nov 18.

PRIMARY OBJECTIVE: Recently, selective internal radiation therapy using yttrium-90 (Y90) glass microspheres (TheraSphere™) was approved for reimbursement by health authorities in France. The PROACTIF study aims to gather data on effectiveness, patient quality of life, and safety with use...

Utility of Early Posttreatment PET/CT Evaluation Using FDG or .

AJR. American journal of roentgenology

Reizine E, Chalaye J, Mule S, Regnault H, Perrin C, Calderaro J, Laurent A, Amaddeo G, Kobeiter H, Tacher V, Itti E, Luciani A.
PMID: 34494448
AJR Am J Roentgenol. 2021 Dec 29;1-11. doi: 10.2214/AJR.21.26485. Epub 2021 Dec 29.

No abstract available.

Syncytialization and prolonged exposure to palmitate impacts BeWo respiration.

Reproduction (Cambridge, England)

Easton ZJW, Delhaes F, Mathers K, Zhao L, Vanderboor CMG, Regnault TRH.
PMID: 33151905
Reproduction. 2021 Jan;161(1):73-88. doi: 10.1530/REP-19-0433.

Placental villous trophoblast mitochondrial respiratory function is critical for a successful pregnancy and environmental influences such as maternal obesity have been associated with respiratory impairment at term. More recently, a gestational high fat diet independent of maternal body composition,...

Immune Profiling of Combined Hepatocellular- Cholangiocarcinoma Reveals Distinct Subtypes and Activation of Gene Signatures Predictive of Response to Immunotherapy.

Clinical cancer research : an official journal of the American Association for Cancer Research

Nguyen CT, Caruso S, Maille P, Beaufrère A, Augustin J, Favre L, Pujals A, Boulagnon-Rombi C, Rhaiem R, Amaddeo G, di Tommaso L, Luciani A, Regnault H, Brustia R, Scatton O, Charlotte F, Brochériou I, Sommacale D, Soussan P, Leroy V, Laurent A, Le VK, Ta VT, Trinh HS, Tran TL, Gentien D, Rapinat A, Nault JC, Allaire M, Mulé S, Zucman-Rossi J, Pawlotsky JM, Tournigand C, Lafdil F, Paradis V, Calderaro J.
PMID: 34785581
Clin Cancer Res. 2021 Nov 16; doi: 10.1158/1078-0432.CCR-21-1219. Epub 2021 Nov 16.

PURPOSE: Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a rare malignancy associated with an overall poor prognosis. We aimed to investigate the immune profile of cHCC-CCA and determine its impact on disease outcome.EXPERIMENTAL DESIGN: We performed a multicenter study of 96 patients...

Maternal Undernourishment in Guinea Pigs Leads to Fetal Growth Restriction with Increased Hypoxic Cells and Oxidative Stress in the Brain.

Developmental neuroscience

Maki Y, Nygard K, Hammond RR, Regnault TRH, Richardson BS.
PMID: 32316015
Dev Neurosci. 2019;41(5):290-299. doi: 10.1159/000506939. Epub 2020 Apr 21.

BACKGROUND: We determined whether maternal nutrient restriction (MNR) in guinea pigs leading to fetal growth restriction (FGR) impacts markers for brain hypoxia and oxidative stress.METHODS: Guinea pigs were fed ad libitum (control) or 70% of the control diet before...

Peroxisome Proliferator-Activated Receptor -β/δ, -γ Agonists and Resveratrol Modulate Hypoxia Induced Changes in Nuclear Receptor Activators of Muscle Oxidative Metabolism.

PPAR research

Regnault TR, Zhao L, Chiu JS, Gottheil SK, Foran A, Yee SP.
PMID: 21113404
PPAR Res. 2010;2010:129173. doi: 10.1155/2010/129173. Epub 2010 Nov 24.

PPAR-α, PPAR-β, and PPAR-γ, and RXR in conjunction with PGC-1α and SIRT1, activate oxidative metabolism genes determining insulin sensitivity. In utero, hypoxia is commonly observed in Intrauterine Growth Restriction (IUGR), and reduced insulin sensitivity is often observed in these...

Corrigendum to "population-based placental weight ratio distributions".

International journal of pediatrics

Macdonald EM, Koval JJ, Natale R, Regnault TR, Campbell MK.
PMID: 25722730
Int J Pediatr. 2015;2015:181257. doi: 10.1155/2015/181257. Epub 2015 Feb 02.

[This corrects the article DOI: 10.1155/2014/291846.].

Utility of Early Posttreatment PET/CT Evaluation Using FDG or .

AJR. American journal of roentgenology

Reizine E, Chalaye J, Mule S, Regnault H, Perrin C, Calderaro J, Laurent A, Amaddeo G, Kobeiter H, Tacher V, Itti E, Luciani A.
PMID: 34494448
AJR Am J Roentgenol. 2021 Sep 08; doi: 10.2214/AJR.21.26485. Epub 2021 Sep 08.

No abstract available.

Gestational age impacts birth to placental weight ratio and umbilical cord oxygen values with implications for the fetal oxygen margin of safety.

Early human development

Richardson BS, de Vrijer B, Brown HK, Stitt L, Choo S, Regnault TRH.
PMID: 34839188
Early Hum Dev. 2021 Nov 20;164:105511. doi: 10.1016/j.earlhumdev.2021.105511. Epub 2021 Nov 20.

BACKGROUND: We determined the impact of gestational age (GA) from near term to term to post-term on birth/placental weight ratio and cord oxygen values with implications for placental transport efficiency for oxygen, fetal OMATERIALS AND METHODS: A hospital database...

Hepatic cytochrome P450 function is reduced by life-long Western diet consumption in guinea pig independent of birth weight.

Life sciences

Wiese MD, Meakin AS, Varcoe TJ, Darby JRT, Sarr O, Kiser P, Bradshaw EL, Regnault TRH, Morrison JL.
PMID: 34774623
Life Sci. 2021 Dec 15;287:120133. doi: 10.1016/j.lfs.2021.120133. Epub 2021 Nov 11.

INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) is characterised by accumulation of triglycerides and cholesterol within the liver and dysregulation of specific hepatic cytochrome P450 (CYPs) activity. CYPs are involved in the metabolism of endogenous and exogenous chemicals. Hepatic CYP...

Showing 1 to 12 of 38 entries