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Beneficial Effects of Remifentanil Against Excitotoxic Brain Damage in Newborn Mice.

Frontiers in neurology

Chollat C, Lecointre M, Leuillier M, Remy-Jouet I, Do Rego JC, Abily-Donval L, Ramdani Y, Richard V, Compagnon P, Dureuil B, Marret S, Gonzalez BJ, Jégou S, Tourrel F.
PMID: 31068895
Front Neurol. 2019 Apr 24;10:407. doi: 10.3389/fneur.2019.00407. eCollection 2019.

No abstract available.

The IL-1β Antibody Gevokizumab Limits Cardiac Remodeling and Coronary Dysfunction in Rats With Heart Failure.

JACC. Basic to translational science

Harouki N, Nicol L, Remy-Jouet I, Henry JP, Dumesnil A, Lejeune A, Renet S, Golding F, Djerada Z, Wecker D, Bolduc V, Bouly M, Roussel J, Richard V, Mulder P.
PMID: 30062160
JACC Basic Transl Sci. 2017 Aug 28;2(4):418-430. doi: 10.1016/j.jacbts.2017.06.005. eCollection 2017 Aug.

This study reports preclinical data showing that the interleukin (IL)-1β modulation is a new promising target in the pathophysiological context of heart failure. Indeed, in nondiabetic Wistar and diabetic Goto-Kakizaki rats with chronic heart failure induced by myocardial infarction,...

Short-and long-term administration of imeglimin counters cardiorenal dysfunction in a rat model of metabolic syndrome.

Endocrinology, diabetes & metabolism

Lachaux M, Soulié M, Hamzaoui M, Bailly A, Nicol L, Rémy-Jouet I, Renet S, Vendeville C, Gluais-Dagorn P, Hallakou-Bozec S, Monteil C, Richard V, Mulder P.
PMID: 32704553
Endocrinol Diabetes Metab. 2020 Apr 16;3(3):e00128. doi: 10.1002/edm2.128. eCollection 2020 Jul.

INTRODUCTION: Imeglimin, a glucose-lowering agent targeting mitochondrial bioenergetics, decreases reactive oxygen species (ROS) overproduction and improves glucose homeostasis. We investigated whether this is associated with protective effects on metabolic syndrome-related left ventricular (LV) and vascular dysfunctions.METHODS: We used Zucker...

Showing 1 to 3 of 3 entries