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An Amphotericin B Derivative Equally Potent to Amphotericin B and with Increased Safety.

PloS one

Antillón A, de Vries AH, Espinosa-Caballero M, Falcón-González JM, Flores Romero D, González-Damián J, Jiménez-Montejo FE, León-Buitimea A, López-Ortiz M, Magaña R, Marrink SJ, Morales-Nava R, Periole X, Reyes-Esparza J, Rodríguez Lozada J, Santiago-Angelino TM, Vargas González MC, Regla I, Carrillo-Tripp M, Fernández-Zertuche M, Rodríguez-Fragoso L, Ortega-Blake I.
PMID: 27683101
PLoS One. 2016 Sep 28;11(9):e0162171. doi: 10.1371/journal.pone.0162171. eCollection 2016.

Amphotericin B is the most potent antimycotic known to date. However due to its large collateral toxicity, its use, although long standing, had been limited. Many attempts have been made to produce derivatives with reduced collateral damage. The molecular...

Cite
Antillón A, de Vries AH, Espinosa-Caballero M, et al. An Amphotericin B Derivative Equally Potent to Amphotericin B and with Increased Safety. PLoS One. 2016;11(9):e0162171doi: 10.1371/journal.pone.0162171.
Antillón, A., de Vries, A. H., Espinosa-Caballero, M., Falcón-González, J. M., Flores Romero, D., González-Damián, J., Jiménez-Montejo, F. E., León-Buitimea, A., López-Ortiz, M., Magaña, R., Marrink, S. J., Morales-Nava, R., Periole, X., Reyes-Esparza, J., Rodríguez Lozada, J., Santiago-Angelino, T. M., Vargas González, M. C., Regla, I., Carrillo-Tripp, M., Fernández-Zertuche, M., Rodríguez-Fragoso, L., & Ortega-Blake, I. (2016). An Amphotericin B Derivative Equally Potent to Amphotericin B and with Increased Safety. PloS one, 11(9), e0162171. https://doi.org/10.1371/journal.pone.0162171
Antillón, Armando, et al. "An Amphotericin B Derivative Equally Potent to Amphotericin B and with Increased Safety." PloS one vol. 11,9 (2016): e0162171. doi: https://doi.org/10.1371/journal.pone.0162171
Antillón A, de Vries AH, Espinosa-Caballero M, Falcón-González JM, Flores Romero D, González-Damián J, Jiménez-Montejo FE, León-Buitimea A, López-Ortiz M, Magaña R, Marrink SJ, Morales-Nava R, Periole X, Reyes-Esparza J, Rodríguez Lozada J, Santiago-Angelino TM, Vargas González MC, Regla I, Carrillo-Tripp M, Fernández-Zertuche M, Rodríguez-Fragoso L, Ortega-Blake I. An Amphotericin B Derivative Equally Potent to Amphotericin B and with Increased Safety. PLoS One. 2016 Sep 28;11(9):e0162171. doi: 10.1371/journal.pone.0162171. eCollection 2016. PMID: 27683101; PMCID: PMC5040443.
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Immuno-modulator metallo-Peptide reduces inflammatory state in obese zucker fa/fa rats.

International journal of biomedical science : IJBS

Gómez-Solís A, Reyes-Esparza J, García-Vázquez F, Alvarez-Ayala E, Rodríguez-Fragoso L.
PMID: 25324698
Int J Biomed Sci. 2014 Sep;10(3):172-81.

Metabolic syndrome is a prothrombotic and proinflammatory chronic state. In obesity, the adipose tissue secretes various adipokines that take part in a variety of physiological and pathophysiological processes, including immunity and inflammation. Previous studies using a liver damage model...

Cite
Gómez-Solís A, Reyes-Esparza J, García-Vázquez F, et al. Immuno-modulator metallo-Peptide reduces inflammatory state in obese zucker fa/fa rats. Int J Biomed Sci. 2014;10(3):172-81
Gómez-Solís, A., Reyes-Esparza, J., García-Vázquez, F., Alvarez-Ayala, E., & Rodríguez-Fragoso, L. (2014). Immuno-modulator metallo-Peptide reduces inflammatory state in obese zucker fa/fa rats. International journal of biomedical science : IJBS, 10(3), 172-81.
Gómez-Solís, Antonieta, et al. "Immuno-modulator metallo-Peptide reduces inflammatory state in obese zucker fa/fa rats." International journal of biomedical science : IJBS vol. 10,3 (2014): 172-81.
Gómez-Solís A, Reyes-Esparza J, García-Vázquez F, Alvarez-Ayala E, Rodríguez-Fragoso L. Immuno-modulator metallo-Peptide reduces inflammatory state in obese zucker fa/fa rats. Int J Biomed Sci. 2014 Sep;10(3):172-81. PMID: 25324698; PMCID: PMC4198424.
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