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Showing 1 to 12 of 79 entries
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An NBD Derivative of the Selective Rat Toxicant Norbormide as a New Probe for Living Cell Imaging.

Frontiers in pharmacology

D'Amore C, Orso G, Fusi F, Pagano MA, Miotto G, Forgiarini A, De Martin S, Castellani G, Ribaudo G, Rennison D, Brimble MA, Hopkins B, Ferrarese A, Bova S.
PMID: 27721792
Front Pharmacol. 2016 Sep 23;7:315. doi: 10.3389/fphar.2016.00315. eCollection 2016.

Norbormide (NRB) is a unique compound that acts directly on rat vascular myocytes to trigger a contractile process, through an as yet unknown mechanism, which results in the selective contraction of rat peripheral arteries. To gain insight into the...

Regional variation of wall shear stress in ascending thoracic aortic aneurysms.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine

Rinaudo A, Pasta S.
PMID: 24942163
Proc Inst Mech Eng H. 2014 Jun;228(6):627-638. doi: 10.1177/0954411914540877. Epub 2014 Jun 18.

The development of an ascending thoracic aortic aneurysm is likely caused by excessive hemodynamic loads exerted on the aneurysmal wall. Computational fluid-dynamic analyses were performed on patient-specific ascending thoracic aortic aneurysms obtained from patients with either bicuspid aortic valve...

Racial Disparities in Virologic Failure and Tolerability During Firstline HIV Antiretroviral Therapy.

Open forum infectious diseases

Bhagwat P, Kapadia SN, Ribaudo HJ, Gulick RM, Currier JS.
PMID: 30793009
Open Forum Infect Dis. 2019 Feb 12;6(2):ofz022. doi: 10.1093/ofid/ofz022. eCollection 2019 Feb.

BACKGROUND: Racial/ethnic disparities in HIV outcomes have persisted despite effective antiretroviral therapy. In a study of initial regimens, we found viral suppression varied by race/ethnicity. In this exploratory analysis, we use clinical and socioeconomic data to assess factors associated...

Assessment of Obesity and Cardiometabolic Status by Integrase Inhibitor Use in REPRIEVE: A Propensity-Weighted Analysis of a Multinational Primary Cardiovascular Prevention Cohort of People With Human Immunodeficiency Virus.

Open forum infectious diseases

Kileel EM, Lo J, Malvestutto C, Fitch KV, Zanni MV, Fichtenbaum CJ, Overton ET, Okeke NL, Kumar P, Joao E, Aberg JA, Martinez E, Currier JS, Douglas PS, Ribaudo HJ, Grinspoon SK.
PMID: 34888395
Open Forum Infect Dis. 2021 Nov 20;8(12):ofab537. doi: 10.1093/ofid/ofab537. eCollection 2021 Dec.

BACKGROUND: Emerging data demonstrate that the use of integrase inhibitor (INSTI)-based antiretroviral treatment (ART) is associated with increased weight, but the cardiometabolic health consequences of increased weight remains poorly understood.METHODS: This analysis examined INSTI use (>6 months) at entry...

Assessment of Coronary Artery Disease With Computed Tomography Angiography and Inflammatory and Immune Activation Biomarkers Among Adults With HIV Eligible for Primary Cardiovascular Prevention.

JAMA network open

Hoffmann U, Lu MT, Foldyna B, Zanni MV, Karady J, Taron J, Zhai BK, Burdo T, Fitch KV, Kileel EM, Williams K, Fichtenbaum CJ, Overton ET, Malvestutto C, Aberg J, Currier J, Sponseller CA, Melbourne K, Floris-Moore M, Van Dam C, Keefer MC, Koletar SL, Douglas PS, Ribaudo H, Mayrhofer T, Grinspoon SK.
PMID: 34185068
JAMA Netw Open. 2021 Jun 01;4(6):e2114923. doi: 10.1001/jamanetworkopen.2021.14923.

IMPORTANCE: Cardiovascular disease (CVD) is increased among people with HIV (PWH), but little is known regarding the prevalence and extent of coronary artery disease (CAD) and associated biological factors in PWH with low to moderate traditional CVD risk.OBJECTIVES: To...

Infant mental health home visiting: intervention dosage and therapist experience interact to support improvements in maternal reflective functioning.

Attachment & human development

Stacks AM, Jester JM, Wong K, Huth-Bocks A, Brophy-Herb H, Lawler J, Riggs J, Ribaudo J, Muzik M, Rosenblum KL.
PMID: 33427582
Attach Hum Dev. 2021 Jan 11;1-23. doi: 10.1080/14616734.2020.1865606. Epub 2021 Jan 11.

This study examined changes in parental reflective functioning (PRF) among mothers enrolled in Infant Mental Health-Home Visiting (IMH-HV) and explored whether parental risk, treatment dosage or therapist experience predicted change in PRF. Participants included 75 mothers and their children...

Amino-Acid-Anthraquinone Click Chemistry Conjugates Selectively Target Human Telomeric G-Quadruplexes.

ChemMedChem

Ongaro A, Desiderati G, Oselladore E, Auricchio D, Memo M, Ribaudo G, Sissi C, Gianoncelli A.
PMID: 34882992
ChemMedChem. 2021 Dec 09;e202100665. doi: 10.1002/cmdc.202100665. Epub 2021 Dec 09.

Guanine-rich sequences are known to fold into G-quadruplex (G4) arrangements, which are present in oncogenes and in the telomeric regions of chromosomes. In particular, G4s represent an obstacle to functioning of telomerase, an enzyme overexpressed in cancer cells causing...

Correction to: The androgen receptor-lncRNASAT1-AKT-p15 axis mediates androgen-induced cellular senescence in prostate cancer cells.

Oncogene

Mirzakhani K, Kallenbach J, Rasa SMM, Ribaudo F, Ungelenk M, Ehsani M, Gong W, Gassler N, Leeder M, Grimm MO, Neri F, Baniahmad A.
PMID: 34930998
Oncogene. 2021 Dec 20; doi: 10.1038/s41388-021-02125-5. Epub 2021 Dec 20.

No abstract available.

Combining Electrospray Mass Spectrometry (ESI-MS) and Computational Techniques in the Assessment of G-Quadruplex Ligands: A Hybrid Approach to Optimize Hit Discovery.

Journal of medicinal chemistry

Ribaudo G, Ongaro A, Oselladore E, Memo M, Gianoncelli A.
PMID: 34510895
J Med Chem. 2021 Sep 23;64(18):13174-13190. doi: 10.1021/acs.jmedchem.1c00962. Epub 2021 Sep 12.

Guanine-rich sequences forming G-quadruplexes (GQs) are present in several genomes, ranging from viral to human. Given their peculiar localization, the induction of GQ formation or GQ stabilization with small molecules represents a strategy for interfering with crucial biological functions....

Study of the phenolic profile of a grape pomace powder and its impact on delaying corn oil oxidation.

Natural product research

Cisneros-Yupanqui M, Zagotto A, Alberton A, Lante A, Zagotto G, Ribaudo G, Rizzi C.
PMID: 32552183
Nat Prod Res. 2022 Jan;36(1):455-459. doi: 10.1080/14786419.2020.1777414. Epub 2020 Jun 19.

The grape pomace, the main by-product from the winemaking industry, contains many bioactive substances that must be valorized. The aim of this study was to assess the total phenolic content (TPC), phenolics profile by using HPLC and the antioxidant...

Corrigendum: Invasive Aquatic Plants as Ecosystem Engineers in an Oligo-Mesotrophic Shallow Lake.

Frontiers in plant science

Ribaudo C, Tison-Rosebery J, Buquet D, Jan G, Jamoneau A, Abril G, Anschutz P, Bertrin V.
PMID: 33763104
Front Plant Sci. 2021 Mar 08;12:656314. doi: 10.3389/fpls.2021.656314. eCollection 2021.

[This corrects the article DOI: 10.3389/fpls.2018.01781.].

The mode of dexamethasone decoration influences avidin-nucleic-acid-nano-assembly organ biodistribution and in vivo drug persistence.

Nanomedicine : nanotechnology, biology, and medicine

Ongaro A, Violatto MB, Casarin E, Pellerani I, Marchini G, Ribaudo G, Salmona M, Carbone M, Passoni A, Gnodi E, Schiavon E, Mattarei A, Barisani D, Invernizzi P, Bigini P, Morpurgo M.
PMID: 34838993
Nanomedicine. 2021 Nov 26;40:102497. doi: 10.1016/j.nano.2021.102497. Epub 2021 Nov 26.

Avidin-Nucleic-Acid-NanoASsemblies (ANANAS) possess natural tropism for the liver and, when loaded with dexamethasone, reduce clinical progression in an autoimmune hepatitis murine model. Here, we investigated the linker chemistry (hydrazide-hydrazone, Hz-Hz, or carbamate hydrazide-hydrazone, Cb-Hz bond) and length (long, 5...

Showing 1 to 12 of 79 entries