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University of Pennsylvania 11th annual conference on statistical issues in clinical trials: Estimands, missing data and sensitivity analysis (morning panel session).

Clinical trials (London, England)

Rockhold FW, Lindblad A, Siegel JP, Molenberghs G.
PMID: 31303021
Clin Trials. 2019 Aug;16(4):350-362. doi: 10.1177/1740774519853573. Epub 2019 Jul 13.

No abstract available.

Development of a competency model and tailored assessment method for high school science teachers utilizing a flipped learning approach.

Educational technology research and development : ETR & D

Barnard M, Dehon E, Compretta C, Notebaert A, Sparkmon W, Meyer E, Stray S, Taylor J, Sullivan D, Rockhold R.
PMID: 33737794
Educ Technol Res Dev. 2020 Oct;68(5):2595-2614. doi: 10.1007/s11423-020-09782-5. Epub 2020 May 22.

Many professional development programs aim to improve student outcomes by enhancing teacher competencies. Effective evaluation of these programs requires a clear delineation of the competencies to be gained. A competency model was developed to evaluate the impact of a...

Myocardial Infarction in the ISCHEMIA Trial: Impact of Different Definitions on Incidence, Prognosis, and Treatment Comparisons.

Circulation

Chaitman BR, Alexander KP, Cyr DD, Berger JS, Reynolds HR, Bangalore S, Boden WE, Lopes RD, Demkow M, Piero Perna G, Riezebos RK, McFalls EO, Banerjee S, Bagai A, Gosselin G, O'Brien SM, Rockhold FW, Waters DD, Thygesen KA, Stone GW, White HD, Maron DJ, Hochman JS.
PMID: 33267610
Circulation. 2021 Feb 23;143(8):790-804. doi: 10.1161/CIRCULATIONAHA.120.047987. Epub 2020 Dec 03.

BACKGROUND: In the ISCHEMIA trial (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches), an initial invasive strategy did not significantly reduce rates of cardiovascular events or all-cause mortality in comparison with a conservative strategy in patients...

Requiring 'independent' statistical analyses for industry sponsored trials?.

Pharmaceutical statistics

Rockhold FW.
PMID: 17080923
Pharm Stat. 2006 Jan-Mar;5(1):5-6. doi: 10.1002/pst.195.

No abstract available.

Gas-surface reactions of nitrate radicals with vinyl-terminated self-assembled monolayers.

Physical chemistry chemical physics : PCCP

Zhang Y, Chapleski RC, Lu JW, Rockhold TH, Troya D, Morris JR.
PMID: 24995705
Phys Chem Chem Phys. 2014 Aug 21;16(31):16659-70. doi: 10.1039/c4cp01982b.

Interfacial reactions between gas-phase nitrate radicals, a key nighttime atmospheric oxidant, and a model unsaturated organic surface have been investigated to determine the reaction kinetics and probable reaction mechanism. The experimental approach employs in situ reflection-absorption infrared spectroscopy (RAIRS)...

Myocardial Infarction in the ISCHEMIA Trial: Impact of Different Definitions on Incidence, Prognosis, and Treatment Comparisons.

Circulation

Chaitman BR, Alexander KP, Cyr DD, Berger JS, Reynolds HR, Bangalore S, Boden WE, Lopes RD, Demkow M, Piero Perna G, Riezebos RK, McFalls EO, Banerjee S, Bagai A, Gosselin G, O'Brien SM, Rockhold FW, Waters DD, Thygesen KA, Stone GW, White HD, Maron DJ, Hochman JS.
PMID: 33267610
Circulation. 2021 Feb 23;143(8):790-804. doi: 10.1161/CIRCULATIONAHA.120.047987. Epub 2020 Dec 03.

BACKGROUND: In the ISCHEMIA trial (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches), an initial invasive strategy did not significantly reduce rates of cardiovascular events or all-cause mortality in comparison with a conservative strategy in patients...

Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials.

Nature communications

Axfors C, Schmitt AM, Janiaud P, Van't Hooft J, Abd-Elsalam S, Abdo EF, Abella BS, Akram J, Amaravadi RK, Angus DC, Arabi YM, Azhar S, Baden LR, Baker AW, Belkhir L, Benfield T, Berrevoets MAH, Chen CP, Chen TC, Cheng SH, Cheng CY, Chung WS, Cohen YZ, Cowan LN, Dalgard O, de Almeida E Val FF, de Lacerda MVG, de Melo GC, Derde L, Dubee V, Elfakir A, Gordon AC, Hernandez-Cardenas CM, Hills T, Hoepelman AIM, Huang YW, Igau B, Jin R, Jurado-Camacho F, Khan KS, Kremsner PG, Kreuels B, Kuo CY, Le T, Lin YC, Lin WP, Lin TH, Lyngbakken MN, McArthur C, McVerry BJ, Meza-Meneses P, Monteiro WM, Morpeth SC, Mourad A, Mulligan MJ, Murthy S, Naggie S, Narayanasamy S, Nichol A, Novack LA, O'Brien SM, Okeke NL, Perez L, Perez-Padilla R, Perrin L, Remigio-Luna A, Rivera-Martinez NE, Rockhold FW, Rodriguez-Llamazares S, Rolfe R, Rosa R, Røsjø H, Sampaio VS, Seto TB, Shahzad M, Soliman S, Stout JE, Thirion-Romero I, Troxel AB, Tseng TY, Turner NA, Ulrich RJ, Walsh SR, Webb SA, Weehuizen JM, Velinova M, Wong HL, Wrenn R, Zampieri FG, Zhong W, Moher D, Goodman SN, Ioannidis JPA, Hemkens LG.
PMID: 33990619
Nat Commun. 2021 May 14;12(1):3001. doi: 10.1038/s41467-021-23559-1.

No abstract available.

Clinical Events Classification (CEC) in Clinical Trials: Report on the Current Landscape and Future Directions - Proceedings from the CEC Summit 2018.

American heart journal

Sharma A, Mahaffey KW, Gibson CM, Hicks KA, Alexander KP, Ali M, Chaitman BR, Held C, Hlatky M, Jones WS, Mehran R, Menon V, Rockhold FW, Seltzer J, Spitzer E, Wilson M, Lopes RD.
PMID: 34973948
Am Heart J. 2021 Dec 30; doi: 10.1016/j.ahj.2021.12.012. Epub 2021 Dec 30.

IMPORTANCE: Clinical events adjudication is pivotal for generating consistent and comparable evidence in clinical trials. The methodology of event adjudication is evolving, but research is needed to develop best practices and spur innovation.OBSERVATIONS: A meeting of stakeholders from regulatory...

Impact of chronic kidney disease on hemoglobin among patients with peripheral artery disease treated with P2Y.

Vascular medicine (London, England)

Hsia J, Kavanagh ST, Hopley CW, Baumgartner I, Berger JS, Fowkes GR, Jones WS, Mahaffey KW, Norgren L, Patel MR, Rockhold F, Blomster J, Katona BG, Hiatt WR, Bonaca MP.
PMID: 34082620
Vasc Med. 2021 Dec;26(6):608-612. doi: 10.1177/1358863X211017641. Epub 2021 Jun 03.

Patients with chronic kidney disease may develop new or more severe anemia when treated with antiplatelet agents due to blood loss in conjunction with impaired erythropoiesis. Because anemia independently predicts limb amputation and mortality among patients with peripheral artery...

Acute Cerebral Artery Constriction in the Spontaneously Hypertensive Rat following Blood and Plasma Administration into the Subarachnoid Space.

Journal of biomedical science

Acuff CG, Hoskins G, Moore NA, Rockhold RW.
PMID: 11725092
J Biomed Sci. 1996 Apr;3(2):117-125. doi: 10.1007/BF02255539.

The purpose of the present study was to demonstrate, using a vascular casting technique, acute vasoconstrictive changes in the cerebral vasculature 1 h following whole-blood or plasma infusion into the subarachnoid space of conscious spontaneously hypertensive rats. Vascular casts...

Rethinking CME: an imperative for academic medicine and faculty development.

Academic medicine : journal of the Association of American Medical Colleges

Davis DA, Prescott J, Fordis CM, Greenberg SB, Dewey CM, Brigham T, Lieberman SA, Rockhold RW, Lieff SJ, Tenner TE.
PMID: 21346497
Acad Med. 2011 Apr;86(4):468-73. doi: 10.1097/ACM.0b013e31820dfacf.

To help address the clinical care gap, a working group discussed the future of faculty development in academic medicine, explored problems within the large, current enterprise devoted to continuing medical education (CME), and described four domains core to its...

Open Science to Address COVID-19: Sharing Data to Make Our Research Investment Go Further.

Therapeutic innovation & regulatory science

Zariffa N, Haggstrom J, Rockhold F.
PMID: 33368019
Ther Innov Regul Sci. 2021 May;55(3):558-560. doi: 10.1007/s43441-020-00250-z. Epub 2020 Dec 24.

No abstract available.

Showing 1 to 12 of 26 entries